OPTC Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description opticin|Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1). [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 26254)
External Link http://www.ncbi.nlm.nih.gov/gene/26254
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Genes

2 interacting proteins for OPTC from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
CRK v-crk avian sarcoma virus CT10 oncogene homolog
OSGEP O-sialoglycoprotein endopeptidase