ORC1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description origin recognition complex, subunit 1|The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is the largest subunit of the ORC complex. While other ORC subunits are stable throughout the cell cycle, the levels of this protein vary during the cell cycle, which has been shown to be controlled by ubiquitin-mediated proteolysis after initiation of DNA replication. This protein is found to be selectively phosphorylated during mitosis. It is also reported to interact with MYST histone acetyltransferase 2 (MyST2/HBO1), a protein involved in control of transcription silencing. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] (NCBI Entrez Gene Database, 4998)
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Genes

409 genes differentially expressed following the ORC1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
IL19 interleukin 19 2.70295
C2ORF66 chromosome 2 open reading frame 66 2.70295
ESR1 estrogen receptor 1 2.70295
OAZ3 ornithine decarboxylase antizyme 3 2.70295
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1 2.70295
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 2.70295
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) 2.70295
SYCP3 synaptonemal complex protein 3 2.70295
CSTL1 cystatin-like 1 2.70295
NUPR1 nuclear protein, transcriptional regulator, 1 2.70295
PLEKHN1 pleckstrin homology domain containing, family N member 1 2.70295
CFAP43 cilia and flagella associated protein 43 2.70295
ZNF536 zinc finger protein 536 2.70295
REC114 REC114 meiotic recombination protein 2.70295
TMIGD3 transmembrane and immunoglobulin domain containing 3 2.70295
HBZ hemoglobin, zeta 2.70295
RHOJ ras homolog family member J 2.70295
GALR3 galanin receptor 3 2.70295
EBI3 Epstein-Barr virus induced 3 2.70295
SLC39A12 solute carrier family 39 (zinc transporter), member 12 2.70295
EGFLAM EGF-like, fibronectin type III and laminin G domains 2.70295
CNR2 cannabinoid receptor 2 (macrophage) 2.70295
GP1BB glycoprotein Ib (platelet), beta polypeptide 2.70295
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 2.70295
EPOP elongin BC and polycomb repressive complex 2 associated protein 2.70295
PCDHGB6 protocadherin gamma subfamily B, 6 2.70288
CUBN cubilin (intrinsic factor-cobalamin receptor) 2.70288
TRH thyrotropin-releasing hormone 2.67655
GPR52 G protein-coupled receptor 52 2.67655
OR52A5 olfactory receptor, family 52, subfamily A, member 5 2.67655
IYD iodotyrosine deiodinase 2.67655
UMOD uromodulin 2.67655
RASA4B RAS p21 protein activator 4B 2.67655
BTC betacellulin 2.67655
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 2.67655
PRODH2 proline dehydrogenase (oxidase) 2 2.67655
BSND barttin CLCNK-type chloride channel accessory beta subunit 2.67655
TNNI1 troponin I type 1 (skeletal, slow) 2.67655
SLC46A3 solute carrier family 46, member 3 2.67655
BTLA B and T lymphocyte associated 2.67655
NCF1 neutrophil cytosolic factor 1 2.67655
NIPSNAP3B nipsnap homolog 3B (C. elegans) 2.67655
TM4SF20 transmembrane 4 L six family member 20 2.67655
OR10A3 olfactory receptor, family 10, subfamily A, member 3 2.67655
SLC25A45 solute carrier family 25, member 45 2.67655
SH2D7 SH2 domain containing 7 2.67655
DPPA3 developmental pluripotency associated 3 2.67655
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative) 2.67655
IL2RA interleukin 2 receptor, alpha 2.67655
LGALS4 lectin, galactoside-binding, soluble, 4 2.67655
CPLX1 complexin 1 2.67655
FGF5 fibroblast growth factor 5 2.67655
THSD1 thrombospondin, type I, domain containing 1 2.67655
LUZP2 leucine zipper protein 2 2.67655
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 2.67655
RNF39 ring finger protein 39 2.67655
RTP1 receptor (chemosensory) transporter protein 1 2.67655
TTPA tocopherol (alpha) transfer protein 2.67655
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 2.67655
CA10 carbonic anhydrase X 2.67655
DUSP10 dual specificity phosphatase 10 2.67655
VSTM2A V-set and transmembrane domain containing 2A 2.67655
C19ORF25 chromosome 19 open reading frame 25 2.67655
FOLR2 folate receptor 2 (fetal) 2.67655
GPR20 G protein-coupled receptor 20 2.67655
TRIM74 tripartite motif containing 74 2.67655
STRA8 stimulated by retinoic acid 8 2.67655
F7 coagulation factor VII (serum prothrombin conversion accelerator) 2.67655
EDDM3A epididymal protein 3A 2.67655
PERP PERP, TP53 apoptosis effector 2.67655
ARRDC2 arrestin domain containing 2 2.67655
EPHB3 EPH receptor B3 2.67655
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.67655
SPMIP2 sperm microtubule inner protein 2 2.67655
SPATS1 spermatogenesis associated, serine-rich 1 2.67655
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 2.67655
ALDOB aldolase B, fructose-bisphosphate 2.67655
KY kyphoscoliosis peptidase 2.67655
RHCG Rh family, C glycoprotein 2.67655
DUSP8 dual specificity phosphatase 8 2.67655
RD3 retinal degeneration 3 2.67655
PLCZ1 phospholipase C, zeta 1 2.67655
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 2.67655
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 2.67655
ARL14EPL ADP-ribosylation factor-like 14 effector protein-like 2.67655
GATA2 GATA binding protein 2 2.67655
EIF2S3B eukaryotic translation initiation factor 2 subunit gamma B 2.67655
GGTA1 glycoprotein alpha-galactosyltransferase 1 (inactive) 2.67655
GPRASP3 G protein-coupled receptor associated sorting protein family member 3 2.67655
FAM240C family with sequence similarity 240 member C 2.67655
FAM240A family with sequence similarity 240 member A 2.67655
CSP2 CS pseudogene 2 2.67655
LOC122526780 uncharacterized LOC122526780 2.67655
LOC124903372 uncharacterized LOC124903372 2.67655
LOC124902436 talanin 2.67655
CFAP276 cilia and flagella associated protein 276 2.67655
CBY2 chibby family member 2 2.67655
PCARE photoreceptor cilium actin regulator 2.67655
CFAP100 cilia and flagella associated protein 100 2.67655
TAFA3 TAFA chemokine like family member 3 2.67655
AJM1 apical junction component 1 homolog 2.67655
CCDC42 coiled-coil domain containing 42 2.67655
LGSN lengsin, lens protein with glutamine synthetase domain 2.67655
GDF6 growth differentiation factor 6 2.67655
LIPC lipase, hepatic 2.67655
ATP13A4 ATPase type 13A4 2.67655
ZNF177 zinc finger protein 177 2.67655
ISM2 isthmin 2 2.67655
MEP1B meprin A, beta 2.67655
NRN1 neuritin 1 2.67655
KLHL35 kelch-like family member 35 2.67655
NCBP2L nuclear cap binding protein subunit 2-like 2.67655
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.67655
SIX3 SIX homeobox 3 2.67655
HLF hepatic leukemia factor 2.67655
FOLR1 folate receptor 1 (adult) 2.67655
ZNF436 zinc finger protein 436 2.67655
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 2.67655
TRIM60 tripartite motif containing 60 2.67655
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1 2.67655
FRK fyn-related Src family tyrosine kinase 2.67655
CDSN corneodesmosin 2.67655
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 2.67655
PDE1B phosphodiesterase 1B, calmodulin-dependent 2.67655
BHLHA9 basic helix-loop-helix family, member a9 2.67655
TFEC transcription factor EC 2.67655
HAPLN2 hyaluronan and proteoglycan link protein 2 2.67655
OR11A1 olfactory receptor, family 11, subfamily A, member 1 2.67655
TMEM236 transmembrane protein 236 2.67655
SP140 SP140 nuclear body protein 2.67655
OLAH oleoyl-ACP hydrolase 2.67655
PARP3 poly (ADP-ribose) polymerase family, member 3 2.67655
OR9Q1 olfactory receptor, family 9, subfamily Q, member 1 2.67655
KRT222 keratin 222, type II 2.67655
GOLGA6B golgin A6 family, member B 2.67655
AKNAD1 AKNA domain containing 1 2.67655
PCDHGA7 protocadherin gamma subfamily A, 7 2.67655
PCDHGA3 protocadherin gamma subfamily A, 3 2.67655
VWA3B von Willebrand factor A domain containing 3B 2.67655
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) 2.67655
VWA7 von Willebrand factor A domain containing 7 2.67655
DSC1 desmocollin 1 2.67655
SEC14L4 SEC14-like 4 (S. cerevisiae) 2.67655
SSC5D scavenger receptor cysteine rich family, 5 domains 2.67655
BTNL8 butyrophilin-like 8 2.67655
BTNL2 butyrophilin-like 2 2.67655
IL13RA2 interleukin 13 receptor, alpha 2 2.67655
ALAS2 5'-aminolevulinate synthase 2 2.67655
CABP7 calcium binding protein 7 2.67655
APOB apolipoprotein B 2.67655
PCDHGB1 protocadherin gamma subfamily B, 1 2.67655
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 2.67655
KCNK9 potassium channel, two pore domain subfamily K, member 9 2.67655
ARHGAP20 Rho GTPase activating protein 20 2.67655
MRLN myoregulin 2.67655
CSTA cystatin A (stefin A) 2.67655
CST1 cystatin SN 2.67655
ZCCHC12 zinc finger, CCHC domain containing 12 2.67655
SIAH3 siah E3 ubiquitin protein ligase family member 3 2.67655
DCDC2C doublecortin domain containing 2C 2.67655
HMGB4 high mobility group box 4 2.67655
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 2.67655
GBX2 gastrulation brain homeobox 2 2.67655
CXORF58 chromosome X open reading frame 58 2.67655
ADRA2B adrenoceptor alpha 2B 2.67655
BTG4 B-cell translocation gene 4 2.67655
LRRC24 leucine rich repeat containing 24 2.67655
LRRC26 leucine rich repeat containing 26 2.67655
FOXS1 forkhead box S1 2.67655
CFI complement factor I 2.67655
CFH complement factor H 2.67655
CALY calcyon neuron-specific vesicular protein 2.67655
PRAC1 prostate cancer susceptibility candidate 1 2.67655
FBXO47 F-box protein 47 2.67655
GTF2A1L general transcription factor IIA, 1-like 2.67655
ZFP92 ZFP92 zinc finger protein 2.67655
TEX11 testis expressed 11 2.67655
ASTL astacin-like metallo-endopeptidase (M12 family) 2.67655
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 2.67655
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 2.67655
NTN5 netrin 5 2.67655
DLX5 distal-less homeobox 5 2.67655
PRSS37 protease, serine, 37 2.67655
CD27 CD27 molecule 2.67655
ITGA8 integrin, alpha 8 2.67655
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 2.67655
FCAR Fc fragment of IgA receptor 2.67655
PAGE2B P antigen family, member 2B 2.67655
PATE2 prostate and testis expressed 2 2.67655
FOXG1 forkhead box G1 2.67655
ICA1L islet cell autoantigen 1,69kDa-like 2.67655
TRAF3IP3 TRAF3 interacting protein 3 2.67655
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 2.67655
OR56B1 olfactory receptor, family 56, subfamily B, member 1 2.67655
RERGL RERG/RAS-like 2.67655
LRRC74B leucine rich repeat containing 74B 2.67655
TMEM86A transmembrane protein 86A 2.67655
MST1R macrophage stimulating 1 receptor 2.67655
SLX1B SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) 2.67655
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 2.67655
SNTN sentan, cilia apical structure protein 2.67655
GRAPL GRB2-related adaptor protein-like 2.67655
ASCL3 achaete-scute family bHLH transcription factor 3 2.67655
OR52A1 olfactory receptor, family 52, subfamily A, member 1 2.67655
MFSD6L major facilitator superfamily domain containing 6-like 2.67655
FGF8 fibroblast growth factor 8 (androgen-induced) 2.67655
NPR3 natriuretic peptide receptor 3 2.67655
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.67655
PRR15L proline rich 15-like 2.67655
SCIN scinderin 2.67655
THEM5 thioesterase superfamily member 5 2.67655
ARL16 ADP-ribosylation factor-like 16 2.67655
ZMYND10 zinc finger, MYND-type containing 10 2.67655
ASCL1 achaete-scute family bHLH transcription factor 1 2.67655
EXOSC6 exosome component 6 2.67655
MROH1 maestro heat-like repeat family member 1 2.61237
TOX2 TOX high mobility group box family member 2 2.60552
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 2.5831
PFN2 profilin 2 2.54541
ULK3 unc-51 like kinase 3 2.51945
WDR72 WD repeat domain 72 2.51258
FCGBP Fc fragment of IgG binding protein 2.51258
FRMD1 FERM domain containing 1 2.51258
S1PR2 sphingosine-1-phosphate receptor 2 2.51258
HCRTR1 hypocretin (orexin) receptor 1 2.51258
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 2.51258
NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1 2.47687
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 2.47687
LEFTY1 left-right determination factor 1 2.47488
ACOT12 acyl-CoA thioesterase 12 2.4741
FDX2 ferredoxin 2 2.43371
OGG1 8-oxoguanine DNA glycosylase 2.42757
TAPBPL TAP binding protein-like 2.42755
MLIP muscular LMNA-interacting protein 2.42755
IRGM immunity-related GTPase family, M 2.42755
SCARA3 scavenger receptor class A, member 3 2.4236
BTBD7 BTB (POZ) domain containing 7 2.42326
RSPRY1 ring finger and SPRY domain containing 1 2.42252
CAPZB capping protein (actin filament) muscle Z-line, beta 2.42072
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 2.41036
SERTAD4 SERTA domain containing 4 2.40019
GID8 GID complex subunit 8 2.37294
TOR1AIP1 torsin A interacting protein 1 2.3572
ZNF337 zinc finger protein 337 2.34602
IGSF9B immunoglobulin superfamily, member 9B 2.32478
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 2.32475
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) 2.32326
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 2.31504
LATS1 large tumor suppressor kinase 1 2.30074
CBX2 chromobox homolog 2 2.29515
TXLNA taxilin alpha 2.29143
IFT57 intraflagellar transport 57 2.2787
PNPLA7 patatin-like phospholipase domain containing 7 2.27863
ZNF579 zinc finger protein 579 2.26825
LRRC75A leucine rich repeat containing 75A 2.25622
TUBGCP5 tubulin, gamma complex associated protein 5 2.22579
PSPH phosphoserine phosphatase 2.20977
DCP2 decapping mRNA 2 2.20977
GASK1A golgi associated kinase 1A 2.20395
DCPH1 damage control phosphatase 1 2.20395
TMEM260 transmembrane protein 260 2.19292
FAAP100 FA core complex associated protein 100 2.18529
SETDB2 SET domain, bifurcated 2 2.18335
MARVELD3 MARVEL domain containing 3 2.17529
AAGAB alpha- and gamma-adaptin binding protein 2.16834
ENC1 ectodermal-neural cortex 1 (with BTB domain) 2.15258
CDK11B cyclin-dependent kinase 11B 2.1377
CLIC1 chloride intracellular channel 1 2.12157
GMPS guanine monphosphate synthase 2.11742
SLBP stem-loop binding protein 2.11273
MPG N-methylpurine-DNA glycosylase 2.11273
ADGRG6 adhesion G protein-coupled receptor G6 2.09538
TMSB10 thymosin beta 10 2.08326
ZNF644 zinc finger protein 644 2.07572
MINDY4 MINDY lysine 48 deubiquitinase 4 2.0708
TMEM132A transmembrane protein 132A 2.04882
GFM2 G elongation factor, mitochondrial 2 2.04623
MEAK7 MTOR associated protein, eak-7 homolog 2.04226
MRFAP1 Morf4 family associated protein 1 2.04138
LRRC20 leucine rich repeat containing 20 2.03721
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 2.02951
SCGN secretagogin, EF-hand calcium binding protein 2.0176
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 2.01573
LYPD3 LY6/PLAUR domain containing 3 2.01305
OMG oligodendrocyte myelin glycoprotein 2.01305
RGS17 regulator of G-protein signaling 17 2.00586
GPR141 G protein-coupled receptor 141 2.0055
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 2.00222
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 2.00158

decreased expression

Symbol Name Standardized Value
KLB klotho beta -2.70295
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 -2.70295
OR2A7 olfactory receptor, family 2, subfamily A, member 7 -2.70295
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.70295
ZBTB7B zinc finger and BTB domain containing 7B -2.70295
SYT4 synaptotagmin IV -2.70295
ZNF837 zinc finger protein 837 -2.70295
HAP1 huntingtin-associated protein 1 -2.70295
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 -2.67655
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 -2.67655
ICAM5 intercellular adhesion molecule 5, telencephalin -2.67655
KIF19 kinesin family member 19 -2.67655
C1ORF146 chromosome 1 open reading frame 146 -2.67655
SGMS2 sphingomyelin synthase 2 -2.67655
IL17C interleukin 17C -2.67655
GGN gametogenetin -2.67655
EIF3CL eukaryotic translation initiation factor 3, subunit C-like -2.67655
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 -2.67655
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -2.67655
RHOXF2 Rhox homeobox family, member 2 -2.67655
CPNE5 copine V -2.67655
MANSC4 MANSC domain containing 4 -2.67655
TTC39B tetratricopeptide repeat domain 39B -2.67655
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -2.67655
ZNF468 zinc finger protein 468 -2.67655
GFRA3 GDNF family receptor alpha 3 -2.67655
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) -2.67655
COLEC10 collectin sub-family member 10 (C-type lectin) -2.67655
TP73 tumor protein p73 -2.67655
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1 -2.67655
RYR3 ryanodine receptor 3 -2.67655
OVGP1 oviductal glycoprotein 1, 120kDa -2.67655
AKR1C1 aldo-keto reductase family 1, member C1 -2.67655
ZNF34 zinc finger protein 34 -2.67655
DIABLO diablo, IAP-binding mitochondrial protein -2.67655
GABRD gamma-aminobutyric acid (GABA) A receptor, delta -2.67655
ACSL6 acyl-CoA synthetase long-chain family member 6 -2.67655
KIF3C kinesin family member 3C -2.67655
TOP6BL TOP6B like initiator of meiotic double strand breaks -2.67655
ALS2CL ALS2 C-terminal like -2.67655
TTC19 tetratricopeptide repeat domain 19 -2.67655
AMH anti-Mullerian hormone -2.67655
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma -2.67655
FCHSD2 FCH and double SH3 domains 2 -2.67655
NFIA nuclear factor I/A -2.67655
PLPP3 phospholipid phosphatase 3 -2.67655
SMIM36 small integral membrane protein 36 -2.67655
CCDC191 coiled-coil domain containing 191 -2.67655
C20ORF204 chromosome 20 open reading frame 204 -2.67655
ARPC5L actin related protein 2/3 complex, subunit 5-like -2.67655
TAPBP TAP binding protein (tapasin) -2.67655
OAF OAF homolog (Drosophila) -2.67655
C1QTNF2 C1q and tumor necrosis factor related protein 2 -2.67655
FICD FIC domain containing -2.67655
PMP22 peripheral myelin protein 22 -2.67655
PILRA paired immunoglobin-like type 2 receptor alpha -2.67655
ZNF541 zinc finger protein 541 -2.67655
TNN tenascin N -2.67655
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) -2.67655
RAB37 RAB37, member RAS oncogene family -2.67655
PRKD1 protein kinase D1 -2.67655
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 -2.67655
RAB3B RAB3B, member RAS oncogene family -2.67655
NHLH1 nescient helix loop helix 1 -2.67655
CCDC177 coiled-coil domain containing 177 -2.67655
ZNF81 zinc finger protein 81 -2.6305
CUZD1 CUB and zona pellucida-like domains 1 -2.62969
ZNF395 zinc finger protein 395 -2.58738
GLYATL1 glycine-N-acyltransferase-like 1 -2.55932
LRRC58 leucine rich repeat containing 58 -2.55701
HAUS3 HAUS augmin-like complex, subunit 3 -2.5526
ABTB3 ankyrin repeat and BTB domain containing 3 -2.49112
REXO5 RNA exonuclease 5 -2.49112
SKAP1 src kinase associated phosphoprotein 1 -2.49112
RIBC2 RIB43A domain with coiled-coils 2 -2.49112
MFSD12 major facilitator superfamily domain containing 12 -2.4298
ZIC2 Zic family member 2 -2.42755
SF3B5 splicing factor 3b, subunit 5, 10kDa -2.4236
SIK3 SIK family kinase 3 -2.4236
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 -2.41394
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 -2.40895
IGHMBP2 immunoglobulin mu binding protein 2 -2.35619
OTUD7A OTU deubiquitinase 7A -2.31504
GRB2 growth factor receptor-bound protein 2 -2.31504
UNC80 unc-80 homolog (C. elegans) -2.30556
SMCO2 single-pass membrane protein with coiled-coil domains 2 -2.30324
SNX30 sorting nexin family member 30 -2.29785
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.2935
FGF12 fibroblast growth factor 12 -2.25069
GAN gigaxonin -2.24083
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -2.22848
CHN1 chimerin 1 -2.22345
ZFP36L2 ZFP36 ring finger protein-like 2 -2.21861
DENND6A DENN/MADD domain containing 6A -2.20977
LPAR4 lysophosphatidic acid receptor 4 -2.20977
INTU inturned planar cell polarity protein -2.18832
RLN2 relaxin 2 -2.17816
FHOD3 formin homology 2 domain containing 3 -2.15749
GAR1 GAR1 ribonucleoprotein -2.15258
MRPL23 mitochondrial ribosomal protein L23 -2.15167
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2 -2.1377
NBPF11 neuroblastoma breakpoint family, member 11 -2.11076
METTL17 methyltransferase like 17 -2.10944
OLFM2 olfactomedin 2 -2.10944
TTL tubulin tyrosine ligase -2.10141
NRXN3 neurexin 3 -2.09712
MALL mal, T-cell differentiation protein-like -2.08752
IGFLR1 IGF-like family receptor 1 -2.08703
TMEM63B transmembrane protein 63B -2.08627
ING5 inhibitor of growth family, member 5 -2.07618
KIDINS220 kinase D-interacting substrate, 220kDa -2.06765
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -2.06307
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 -2.06286
ATN1 atrophin 1 -2.05539
KCNK13 potassium channel, two pore domain subfamily K, member 13 -2.03937
TRUB1 TruB pseudouridine (psi) synthase family member 1 -2.03415
RNF185 ring finger protein 185 -2.0055
RYK receptor-like tyrosine kinase -2.00535
RBM34 RNA binding motif protein 34 -2.00535
HIPK2 homeodomain interacting protein kinase 2 -2.00026