| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | OTS514 perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the OTS514_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | 0.188881 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.111506 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0996162 |
| CD44 | CD44 molecule (Indian blood group) | 0.0800797 |
| LOX | lysyl oxidase | 0.0755597 |
| FLNA | filamin A, alpha | 0.0750632 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0660207 |
| THBS2 | thrombospondin 2 | 0.0620542 |
| LOXL2 | lysyl oxidase-like 2 | 0.0568974 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0495759 |
| PLAT | plasminogen activator, tissue | 0.0478013 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0437042 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0420211 |
| C1D | C1D nuclear receptor corepressor | 0.0411814 |
| L1CAM | L1 cell adhesion molecule | 0.039933 |
| COL5A1 | collagen, type V, alpha 1 | 0.0392895 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0382425 |
| FLNB | filamin B, beta | 0.0380548 |
| PKM | pyruvate kinase, muscle | 0.0366868 |
| LDHA | lactate dehydrogenase A | 0.0364984 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0353228 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0319915 |
| PGK1 | phosphoglycerate kinase 1 | 0.0313062 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0287326 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0284635 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0282406 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0276423 |
| GLIS3 | GLIS family zinc finger 3 | 0.0275663 |
| MB21D2 | Mab-21 domain containing 2 | 0.0272505 |
| SEPTIN9 | septin 9 | 0.0265577 |
| MYADM | myeloid-associated differentiation marker | 0.0257211 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0256041 |
| NAV1 | neuron navigator 1 | 0.0252004 |
| ATP13A3 | ATPase type 13A3 | 0.0250246 |
| APP | amyloid beta (A4) precursor protein | 0.0244669 |
| TLE4 | transducin-like enhancer of split 4 | 0.0241357 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.024097 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0239346 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0237326 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0234864 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0230405 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0226839 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0210537 |
| NEK7 | NIMA-related kinase 7 | 0.0210183 |
| CTSB | cathepsin B | 0.0207739 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0207414 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0207273 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.020486 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0204332 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0203605 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0202262 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0199218 |
| GANAB | glucosidase, alpha; neutral AB | 0.0198998 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0189391 |
| ZNF207 | zinc finger protein 207 | 0.0185319 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.018454 |
| PLEC | plectin | 0.0183114 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.018109 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0178972 |
| ERBIN | erbb2 interacting protein | 0.0177706 |
| FAT1 | FAT atypical cadherin 1 | 0.0177338 |
| AUTS2 | autism susceptibility candidate 2 | 0.0176565 |
| EXOC6B | exocyst complex component 6B | 0.0174361 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0174193 |
| GSE1 | Gse1 coiled-coil protein | 0.0173227 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0170791 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0170764 |
| NCKAP1 | NCK-associated protein 1 | 0.0170294 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0167363 |
| RNF213 | ring finger protein 213 | 0.016658 |
| RUNX1 | runt-related transcription factor 1 | 0.0166336 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0161829 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0161496 |
| DST | dystonin | 0.0161099 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0160666 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0159796 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0158959 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.015815 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.015812 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0157006 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0155954 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0155591 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0154036 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.0148433 |
| PTK2 | protein tyrosine kinase 2 | 0.0147212 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0146966 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.0146705 |
| DCLK2 | doublecortin-like kinase 2 | 0.0143401 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0142545 |
| NAV2 | neuron navigator 2 | 0.0142417 |
| SMYD3 | SET and MYND domain containing 3 | 0.0141803 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0141083 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0140638 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.0139508 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0135854 |
| TGFB1 | transforming growth factor, beta 1 | 0.0135737 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0135115 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0134847 |
| RRM2 | ribonucleotide reductase M2 | 0.0133788 |
| HDAC9 | histone deacetylase 9 | 0.0133242 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.351384 |
| TMSB10 | thymosin beta 10 | -0.278292 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.269236 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.245378 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.180604 |
| PTMA | prothymosin, alpha | -0.101943 |
| AHNAK | AHNAK nucleoprotein | -0.0967827 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0783147 |
| S100A10 | S100 calcium binding protein A10 | -0.0740732 |
| TPM4 | tropomyosin 4 | -0.0679284 |
| CANX | calnexin | -0.0659481 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0613167 |
| CSTB | cystatin B (stefin B) | -0.0556235 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0538135 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0530621 |
| LMNA | lamin A/C | -0.0518555 |
| B2M | beta-2-microglobulin | -0.0500335 |
| S100A6 | S100 calcium binding protein A6 | -0.0498402 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0422368 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0410134 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0408649 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0399035 |
| SUCNR1 | succinate receptor 1 | -0.0397869 |
| FTL | ferritin, light polypeptide | -0.0387332 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.037914 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0375279 |
| CENPF | centromere protein F, 350/400kDa | -0.0367996 |
| TMSB4X | thymosin beta 4, X-linked | -0.035836 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0328831 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0326614 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0321221 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0297648 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0295537 |
| SEPTIN7 | septin 7 | -0.0288296 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0288165 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0287507 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0285715 |
| INSIG1 | insulin induced gene 1 | -0.0278542 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0276506 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0272291 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0270138 |
| HLA-B | major histocompatibility complex, class I, B | -0.025928 |
| GOLGB1 | golgin B1 | -0.025914 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0258439 |
| RRBP1 | ribosome binding protein 1 | -0.025803 |
| SEC61G | Sec61 gamma subunit | -0.0257706 |
| MAP1B | microtubule-associated protein 1B | -0.0241764 |
| RPS24 | ribosomal protein S24 | -0.0240566 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0239571 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0235541 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0234248 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0229348 |
| ENO1 | enolase 1, (alpha) | -0.0226509 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0225427 |
| LRRC17 | leucine rich repeat containing 17 | -0.0222204 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0219767 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0218884 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0216475 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0208163 |
| RPS19 | ribosomal protein S19 | -0.0205625 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0205346 |
| FN1 | fibronectin 1 | -0.020397 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0202755 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0202389 |
| GOLGA4 | golgin A4 | -0.0199429 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0199178 |
| E2F7 | E2F transcription factor 7 | -0.0196482 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0195105 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0195075 |
| RPS8 | ribosomal protein S8 | -0.0191366 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0191062 |
| IL7R | interleukin 7 receptor | -0.0190067 |
| FLT1 | fms-related tyrosine kinase 1 | -0.01894 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0188917 |
| TAGLN2 | transgelin 2 | -0.0187838 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0187633 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0186917 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0185902 |
| CALD1 | caldesmon 1 | -0.0184263 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.018413 |
| RPL37A | ribosomal protein L37a | -0.0183996 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0183321 |
| UBC | ubiquitin C | -0.0182636 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0182218 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0180865 |
| KRT81 | keratin 81, type II | -0.0180146 |
| MX2 | MX dynamin-like GTPase 2 | -0.0176957 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0176857 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0173806 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.017323 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0173043 |
| CBX3 | chromobox homolog 3 | -0.0171297 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0167262 |
| POTEF | POTE ankyrin domain family, member F | -0.0167 |
| RPL31 | ribosomal protein L31 | -0.0166599 |
| S100A11 | S100 calcium binding protein A11 | -0.016603 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0165255 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.016386 |
| RPL34 | ribosomal protein L34 | -0.0163563 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0162529 |
