| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | OTS514 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the OTS514_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0947379 |
| TLE4 | transducin-like enhancer of split 4 | 0.0868664 |
| IGF2 | insulin-like growth factor 2 | 0.0825504 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0680882 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0631649 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0610167 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0545768 |
| KLHL13 | kelch-like family member 13 | 0.0514936 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0511801 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0498002 |
| PCDH9 | protocadherin 9 | 0.0479725 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0455426 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.044425 |
| BPTF | bromodomain PHD finger transcription factor | 0.0424591 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0389922 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0387865 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0378118 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0375909 |
| GLCCI1 | glucocorticoid induced 1 | 0.0374545 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0367628 |
| SIK3 | SIK family kinase 3 | 0.0367274 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0366011 |
| AOPEP | aminopeptidase O (putative) | 0.0362213 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0360257 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.035735 |
| RNF213 | ring finger protein 213 | 0.0353393 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0342654 |
| HELZ | helicase with zinc finger | 0.0339865 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0334148 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0326237 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0322519 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0321265 |
| GAB2 | GRB2-associated binding protein 2 | 0.0319924 |
| NFIB | nuclear factor I/B | 0.0319011 |
| MEIS2 | Meis homeobox 2 | 0.0316314 |
| GATA3 | GATA binding protein 3 | 0.0310898 |
| FMN1 | formin 1 | 0.0309497 |
| FOXO3 | forkhead box O3 | 0.0306049 |
| MED13 | mediator complex subunit 13 | 0.0301907 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0300794 |
| RUNX1 | runt-related transcription factor 1 | 0.0298598 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0294682 |
| FHIT | fragile histidine triad | 0.0289146 |
| NPAS2 | neuronal PAS domain protein 2 | 0.028845 |
| SMYD3 | SET and MYND domain containing 3 | 0.0287116 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0286905 |
| LSAMP | limbic system-associated membrane protein | 0.0281517 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0278261 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0275927 |
| PTEN | phosphatase and tensin homolog | 0.027387 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0273405 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0273175 |
| PDE10A | phosphodiesterase 10A | 0.0268275 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0266508 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0261302 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0260917 |
| TBX2 | T-box 2 | 0.0259294 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0259264 |
| SPAG9 | sperm associated antigen 9 | 0.0257691 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0255912 |
| MMP2 | matrix metallopeptidase 2 | 0.0253225 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0251973 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0248621 |
| USP22 | ubiquitin specific peptidase 22 | 0.0248585 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0247788 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0243765 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0242535 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.0240454 |
| CUL3 | cullin 3 | 0.0234423 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.02344 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0231665 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0230364 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0229927 |
| RAD51B | RAD51 paralog B | 0.0229039 |
| GPHN | gephyrin | 0.0228679 |
| CCNL1 | cyclin L1 | 0.0227195 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0226563 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0226324 |
| PRKCA | protein kinase C, alpha | 0.0225789 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0224772 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0222793 |
| STOX2 | storkhead box 2 | 0.0221534 |
| CCAR1 | cell division cycle and apoptosis regulator 1 | 0.0221124 |
| NRP1 | neuropilin 1 | 0.0221018 |
| ZNF331 | zinc finger protein 331 | 0.0220353 |
| RALYL | RALY RNA binding protein-like | 0.0218266 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0218081 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0217044 |
| RBM33 | RNA binding motif protein 33 | 0.0215712 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0215553 |
| CREBBP | CREB binding protein | 0.0215268 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0215115 |
| DGKH | diacylglycerol kinase, eta | 0.0215031 |
| PALLD | palladin, cytoskeletal associated protein | 0.0214138 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0213936 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0212489 |
| IRS1 | insulin receptor substrate 1 | 0.0211637 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0208466 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0204735 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0203961 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.453433 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.154416 |
| PTMA | prothymosin, alpha | -0.140309 |
| VIM | vimentin | -0.126204 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0925137 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0721096 |
| CANX | calnexin | -0.0647427 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0629064 |
| IER3 | immediate early response 3 | -0.0622512 |
| RPL23 | ribosomal protein L23 | -0.0595479 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0546014 |
| RPS24 | ribosomal protein S24 | -0.0509535 |
| RPL31 | ribosomal protein L31 | -0.0472833 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0463499 |
| COL3A1 | collagen, type III, alpha 1 | -0.0440304 |
| SCG2 | secretogranin II | -0.0431885 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0412224 |
| LPIN1 | lipin 1 | -0.0405146 |
| RPL19 | ribosomal protein L19 | -0.0399604 |
| RPS19 | ribosomal protein S19 | -0.0378244 |
| GPC5 | glypican 5 | -0.0366702 |
| TMSB10 | thymosin beta 10 | -0.0363267 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0360102 |
| ENO1 | enolase 1, (alpha) | -0.0328658 |
| MCL1 | myeloid cell leukemia 1 | -0.0328289 |
| MAP4 | microtubule-associated protein 4 | -0.0323496 |
| GOLGB1 | golgin B1 | -0.0322894 |
| CENPF | centromere protein F, 350/400kDa | -0.0317736 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0315319 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0307752 |
| RPS5 | ribosomal protein S5 | -0.0304764 |
| FN1 | fibronectin 1 | -0.0297293 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0294339 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0294123 |
| ATRNL1 | attractin-like 1 | -0.0293376 |
| CCDC47 | coiled-coil domain containing 47 | -0.0288229 |
| LMNA | lamin A/C | -0.028398 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0278414 |
| MAP1B | microtubule-associated protein 1B | -0.0278184 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0275021 |
| EGR1 | early growth response 1 | -0.0274198 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0272823 |
| RPLP1 | ribosomal protein, large, P1 | -0.026989 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0261063 |
| RPL12 | ribosomal protein L12 | -0.0260849 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0258479 |
| RO60 | Ro60, Y RNA binding protein | -0.0256376 |
| RPS12 | ribosomal protein S12 | -0.0256368 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0255198 |
| FAM13A | family with sequence similarity 13, member A | -0.0248472 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0247722 |
| RPS6 | ribosomal protein S6 | -0.0247617 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0247427 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0244716 |
| MTPN | myotrophin | -0.0240328 |
| NPR2 | natriuretic peptide receptor 2 | -0.0239516 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0239033 |
| RSF1 | remodeling and spacing factor 1 | -0.0238695 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0238649 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.023824 |
| RPL34 | ribosomal protein L34 | -0.0236316 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0236135 |
| CRH | corticotropin releasing hormone | -0.0235927 |
| DNM3 | dynamin 3 | -0.023478 |
| SRP72 | signal recognition particle 72kDa | -0.0233061 |
| VCL | vinculin | -0.0231288 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0230575 |
| YBX1 | Y box binding protein 1 | -0.022974 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0229661 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0229606 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0229368 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0228436 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0226247 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0226159 |
| RPS8 | ribosomal protein S8 | -0.0225445 |
| TKT | transketolase | -0.0223343 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0223106 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0223088 |
| RPL32 | ribosomal protein L32 | -0.0221732 |
| RPLP0 | ribosomal protein, large, P0 | -0.0217811 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0216609 |
| RPL7A | ribosomal protein L7a | -0.0215041 |
| RPS27 | ribosomal protein S27 | -0.0212122 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0209573 |
| TPI1 | triosephosphate isomerase 1 | -0.0209535 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0209077 |
| STC1 | stanniocalcin 1 | -0.0208096 |
| RPS14 | ribosomal protein S14 | -0.0207851 |
| DTNA | dystrobrevin, alpha | -0.0205868 |
| UBB | ubiquitin B | -0.0204666 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.020442 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0203149 |
| SUCO | SUN domain containing ossification factor | -0.0202486 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0195534 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0195028 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0194887 |
| RPL38 | ribosomal protein L38 | -0.0194868 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0194491 |
| AHR | aryl hydrocarbon receptor | -0.0194015 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0193324 |
