| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | OTS514 perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the OTS514_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.124297 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0700819 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0669551 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0642089 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0628943 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0565133 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0559036 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0481091 |
| CCNL1 | cyclin L1 | 0.0451743 |
| SMAD3 | SMAD family member 3 | 0.0438659 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0437197 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0424178 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0419228 |
| FNIP1 | folliculin interacting protein 1 | 0.0415859 |
| AHI1 | Abelson helper integration site 1 | 0.0408124 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0396683 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0380649 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0352751 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0345099 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0344508 |
| COG6 | component of oligomeric golgi complex 6 | 0.0331705 |
| YAP1 | Yes-associated protein 1 | 0.0328937 |
| CALR | calreticulin | 0.0328436 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0324679 |
| PDZD8 | PDZ domain containing 8 | 0.0320777 |
| SEC24D | SEC24 family member D | 0.0317821 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0310775 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0305796 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0296066 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0292264 |
| RNF43 | ring finger protein 43 | 0.0289942 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0284296 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0282455 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0274492 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0274487 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0272768 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0260971 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0252487 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0250959 |
| DST | dystonin | 0.02501 |
| LCN2 | lipocalin 2 | 0.0249773 |
| UBAP1 | ubiquitin associated protein 1 | 0.0245125 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0243191 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.023907 |
| GOLGA4 | golgin A4 | 0.0236518 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0236269 |
| UFM1 | ubiquitin-fold modifier 1 | 0.0233524 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0233102 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0231888 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0231467 |
| UBL3 | ubiquitin-like 3 | 0.0230209 |
| HELZ | helicase with zinc finger | 0.0229513 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0228203 |
| FNIP2 | folliculin interacting protein 2 | 0.0227421 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.022702 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0223233 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0223212 |
| PMM2 | phosphomannomutase 2 | 0.022247 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0221621 |
| DNM2 | dynamin 2 | 0.0221559 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0220989 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0220527 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0220373 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0219726 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0218259 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0214645 |
| SRP54 | signal recognition particle 54kDa | 0.0214592 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0214398 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0213559 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | 0.0212534 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0211618 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0210125 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0203202 |
| TRIM2 | tripartite motif containing 2 | 0.0200148 |
| RAB1A | RAB1A, member RAS oncogene family | 0.019955 |
| ZNF207 | zinc finger protein 207 | 0.0199524 |
| MEIS2 | Meis homeobox 2 | 0.0199304 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0198772 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0198698 |
| RBM33 | RNA binding motif protein 33 | 0.0196633 |
| TMEM39A | transmembrane protein 39A | 0.0196319 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0193207 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0193052 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0192825 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0192495 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0191819 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0189662 |
| USPL1 | ubiquitin specific peptidase like 1 | 0.0187372 |
| TOX3 | TOX high mobility group box family member 3 | 0.0187084 |
| AGR2 | anterior gradient 2 | 0.0186564 |
| COPA | coatomer protein complex, subunit alpha | 0.0185246 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0184688 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0184388 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0184301 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0183852 |
| AOPEP | aminopeptidase O (putative) | 0.0183366 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.018322 |
| RBM47 | RNA binding motif protein 47 | 0.0181994 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0180806 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0180214 |
| Symbol | Name | Standardized Value |
|---|---|---|
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.113965 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0934756 |
| RIGI | RNA sensor RIG-I | -0.0865093 |
| B2M | beta-2-microglobulin | -0.082869 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0775431 |
| LYZ | lysozyme | -0.0722541 |
| PLSCR2 | phospholipid scramblase 2 | -0.0684524 |
| MX1 | MX dynamin-like GTPase 1 | -0.0678603 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0663135 |
| PTMA | prothymosin, alpha | -0.0655399 |
| EZR | ezrin | -0.064772 |
| MX2 | MX dynamin-like GTPase 2 | -0.0631737 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0627041 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0626243 |
| NPSR1 | neuropeptide S receptor 1 | -0.0614579 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0596474 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0567547 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0565205 |
| SP100 | SP100 nuclear antigen | -0.0546687 |
| LAMA4 | laminin, alpha 4 | -0.052882 |
| VCL | vinculin | -0.0522684 |
| PLSCR1 | phospholipid scramblase 1 | -0.0518263 |
| XAF1 | XIAP associated factor 1 | -0.046343 |
| ITGA6 | integrin, alpha 6 | -0.046269 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.044384 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0429257 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0409864 |
| PERP | PERP, TP53 apoptosis effector | -0.0402187 |
| ANXA2 | annexin A2 | -0.0391192 |
| RNF213 | ring finger protein 213 | -0.0389244 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0385849 |
| TMSB10 | thymosin beta 10 | -0.0376818 |
| ASPH | aspartate beta-hydroxylase | -0.0364759 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0340646 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0338883 |
| NCKAP5 | NCK-associated protein 5 | -0.0335202 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0333925 |
| APOL1 | apolipoprotein L, 1 | -0.0330273 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0328548 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0323191 |
| IFNGR1 | interferon gamma receptor 1 | -0.0315029 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0314391 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0311257 |
| HLA-E | major histocompatibility complex, class I, E | -0.0309912 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.030635 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.030446 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0303144 |
| AHNAK | AHNAK nucleoprotein | -0.0296138 |
| HLA-B | major histocompatibility complex, class I, B | -0.0290357 |
| TNS4 | tensin 4 | -0.0289912 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0289262 |
| SDC4 | syndecan 4 | -0.0288042 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0285855 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0285726 |
| LAP3 | leucine aminopeptidase 3 | -0.028397 |
| EPCAM | epithelial cell adhesion molecule | -0.0279791 |
| TSC22D1 | TSC22 domain family, member 1 | -0.027632 |
| INTS6 | integrator complex subunit 6 | -0.0274233 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.027404 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0273925 |
| ENO1 | enolase 1, (alpha) | -0.0268568 |
| MCL1 | myeloid cell leukemia 1 | -0.0259603 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.025632 |
| CST3 | cystatin C | -0.0253665 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0252215 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0251519 |
| PMP22 | peripheral myelin protein 22 | -0.0247646 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0247456 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0246108 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0243315 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0242141 |
| TPM4 | tropomyosin 4 | -0.0238196 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0237627 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0233381 |
| SQSTM1 | sequestosome 1 | -0.0230968 |
| FBXO39 | F-box protein 39 | -0.0228424 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0227255 |
| TFRC | transferrin receptor | -0.0223386 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.022309 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0221413 |
| DSPP | dentin sialophosphoprotein | -0.0219352 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0217397 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0213891 |
| S100A10 | S100 calcium binding protein A10 | -0.0213203 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0212447 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0211708 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0206874 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0206853 |
| POU2F2 | POU class 2 homeobox 2 | -0.0203411 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0203019 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0199963 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0196951 |
| EGR1 | early growth response 1 | -0.0196267 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0191128 |
| SSH2 | slingshot protein phosphatase 2 | -0.0189578 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0188021 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0187485 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0184895 |
| TUFT1 | tuftelin 1 | -0.0184524 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0180829 |
