| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | OTS514 perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the OTS514_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MTSS1 | metastasis suppressor 1 | 0.137404 |
| TGM2 | transglutaminase 2 | 0.0789929 |
| PODXL | podocalyxin-like | 0.0721865 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0637733 |
| MSN | moesin | 0.0536622 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0491897 |
| MT1E | metallothionein 1E | 0.0462915 |
| LAMA5 | laminin, alpha 5 | 0.0449044 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0443484 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0437918 |
| PCDH1 | protocadherin 1 | 0.0416044 |
| NAV2 | neuron navigator 2 | 0.0406178 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0397629 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.039388 |
| INTS6 | integrator complex subunit 6 | 0.0393251 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0364634 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0315206 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0312964 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0307209 |
| SMAD3 | SMAD family member 3 | 0.0303752 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.030293 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0278022 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0273715 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0270573 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0261813 |
| DOK5 | docking protein 5 | 0.0251125 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0241556 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0239798 |
| FNIP1 | folliculin interacting protein 1 | 0.0238402 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0236604 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0234922 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0234568 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0233402 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0233345 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0233178 |
| CLIC4 | chloride intracellular channel 4 | 0.0230464 |
| RNF217 | ring finger protein 217 | 0.0229049 |
| VEGFA | vascular endothelial growth factor A | 0.0224124 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.022346 |
| LYST | lysosomal trafficking regulator | 0.0215051 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.02142 |
| IGF2 | insulin-like growth factor 2 | 0.0214114 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0214026 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0211336 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0211027 |
| AOPEP | aminopeptidase O (putative) | 0.0207908 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0205299 |
| RAD51B | RAD51 paralog B | 0.0198489 |
| OSMR | oncostatin M receptor | 0.0197889 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0197738 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.019749 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0196259 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.0195453 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0195222 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0195086 |
| MXRA5 | matrix-remodelling associated 5 | 0.0194126 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0190816 |
| ATP9A | ATPase, class II, type 9A | 0.0188203 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0187953 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0186441 |
| NDRG1 | N-myc downstream regulated 1 | 0.0186215 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.0183808 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0182436 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.01811 |
| CD68 | CD68 molecule | 0.0180679 |
| C1D | C1D nuclear receptor corepressor | 0.0180666 |
| PLS3 | plastin 3 | 0.0180005 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0179833 |
| COG6 | component of oligomeric golgi complex 6 | 0.0179109 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | 0.017866 |
| FLNA | filamin A, alpha | 0.0178528 |
| CSMD2 | CUB and Sushi multiple domains 2 | 0.0176272 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0175591 |
| YOD1 | YOD1 deubiquitinase | 0.0171429 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0170524 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0169817 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0165468 |
| TRIM25 | tripartite motif containing 25 | 0.0162363 |
| TBC1D2 | TBC1 domain family, member 2 | 0.0161899 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0161299 |
| EGFR | epidermal growth factor receptor | 0.0160814 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0160328 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0159878 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.015953 |
| LUZP1 | leucine zipper protein 1 | 0.0156431 |
| EFNA5 | ephrin-A5 | 0.0155822 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0154694 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0154037 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0153962 |
| RELA | v-rel avian reticuloendotheliosis viral oncogene homolog A | 0.0151126 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0151079 |
| MT2A | metallothionein 2A | 0.0149154 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0148438 |
| RCOR1 | REST corepressor 1 | 0.01472 |
| SLC38A2 | solute carrier family 38, member 2 | 0.014706 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.014668 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0146435 |
| ATXN1 | ataxin 1 | 0.0143708 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0143687 |
| ZNF395 | zinc finger protein 395 | 0.014226 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.17157 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.166617 |
| AHNAK | AHNAK nucleoprotein | -0.147623 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.129866 |
| PTMA | prothymosin, alpha | -0.12608 |
| TMSB10 | thymosin beta 10 | -0.122853 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.115171 |
| TMSB4X | thymosin beta 4, X-linked | -0.103928 |
| S100A10 | S100 calcium binding protein A10 | -0.0944089 |
| EMP1 | epithelial membrane protein 1 | -0.0940394 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0926616 |
| LMNA | lamin A/C | -0.0916152 |
| FLNB | filamin B, beta | -0.0907086 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0867504 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0854132 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0848447 |
| ITGA6 | integrin, alpha 6 | -0.0848394 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0808155 |
| SULF1 | sulfatase 1 | -0.0730844 |
| CLU | clusterin | -0.0707531 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0683821 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0658593 |
| EZR | ezrin | -0.0650165 |
| ENO1 | enolase 1, (alpha) | -0.0635158 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0633108 |
| ANXA2 | annexin A2 | -0.0629754 |
| H1-0 | H1.0 linker histone | -0.0629451 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0592329 |
| KRT17 | keratin 17, type I | -0.058431 |
| ANLN | anillin, actin binding protein | -0.0578082 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0571855 |
| RPS21 | ribosomal protein S21 | -0.0569659 |
| CANX | calnexin | -0.0567574 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0547811 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0535394 |
| RBM39 | RNA binding motif protein 39 | -0.0503663 |
| NEK7 | NIMA-related kinase 7 | -0.0502855 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0476634 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0457836 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0456716 |
| RPS8 | ribosomal protein S8 | -0.0455726 |
| OGA | O-GlcNAcase | -0.0454665 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.04391 |
| CAVIN1 | caveolae associated protein 1 | -0.0431336 |
| MYOF | myoferlin | -0.0422989 |
| ANXA1 | annexin A1 | -0.041409 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0406814 |
| KRT6A | keratin 6A, type II | -0.0402467 |
| MECOM | MDS1 and EVI1 complex locus | -0.0402096 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0397011 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0395841 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0395436 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0393829 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0384962 |
| RPL8 | ribosomal protein L8 | -0.0384576 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0381944 |
| RPLP1 | ribosomal protein, large, P1 | -0.0375421 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0370629 |
| CUL4B | cullin 4B | -0.036905 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0367793 |
| NRG1 | neuregulin 1 | -0.0365161 |
| TPX2 | TPX2, microtubule-associated | -0.0360372 |
| MKI67 | marker of proliferation Ki-67 | -0.036024 |
| RPLP2 | ribosomal protein, large, P2 | -0.035973 |
| RPS3 | ribosomal protein S3 | -0.0356347 |
| GNAS | GNAS complex locus | -0.0344122 |
| S100A2 | S100 calcium binding protein A2 | -0.0340558 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0340328 |
| RLF | rearranged L-myc fusion | -0.0327811 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.032624 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0325765 |
| S100A6 | S100 calcium binding protein A6 | -0.0324699 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.032365 |
| SERINC3 | serine incorporator 3 | -0.03218 |
| RPL11 | ribosomal protein L11 | -0.0319494 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.031941 |
| CALU | calumenin | -0.0319372 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0313913 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0313693 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0312467 |
| MORF4L2 | mortality factor 4 like 2 | -0.0311536 |
| YBX3 | Y box binding protein 3 | -0.0310522 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0308109 |
| RPS24 | ribosomal protein S24 | -0.0306276 |
| PALLD | palladin, cytoskeletal associated protein | -0.0305495 |
| GOLGA4 | golgin A4 | -0.0303982 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0303437 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0296927 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0296827 |
| BCL2L1 | BCL2-like 1 | -0.0292362 |
| RRBP1 | ribosome binding protein 1 | -0.0291798 |
| TKT | transketolase | -0.029125 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0289895 |
| RPS27A | ribosomal protein S27a | -0.0289345 |
| FOXP1 | forkhead box P1 | -0.0286529 |
| YBX1 | Y box binding protein 1 | -0.0284155 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0284032 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.028285 |
| RPS19 | ribosomal protein S19 | -0.0282781 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0281885 |
