| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | OTS514 perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the OTS514_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0901964 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0892288 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.069102 |
| MYO1E | myosin IE | 0.0635707 |
| MUC13 | mucin 13, cell surface associated | 0.0474737 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0470225 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0459403 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0445072 |
| B2M | beta-2-microglobulin | 0.0444141 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0403179 |
| MT2A | metallothionein 2A | 0.038674 |
| EXT1 | exostosin glycosyltransferase 1 | 0.038484 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0369573 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0358625 |
| RPS6 | ribosomal protein S6 | 0.0350322 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0350111 |
| NEBL | nebulette | 0.0331366 |
| RIGI | RNA sensor RIG-I | 0.0324168 |
| PGK1 | phosphoglycerate kinase 1 | 0.0311651 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0301315 |
| RPL35A | ribosomal protein L35a | 0.0281837 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0280127 |
| RPS12 | ribosomal protein S12 | 0.0279038 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0269424 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0263856 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0245741 |
| LMO7 | LIM domain 7 | 0.0244247 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0241427 |
| RPLP0 | ribosomal protein, large, P0 | 0.0236328 |
| RPS27 | ribosomal protein S27 | 0.0234223 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0231148 |
| LOC112694756 | uncharaterized LOC112694756 | 0.02305 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.022941 |
| TFF1 | trefoil factor 1 | 0.0226075 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0222996 |
| RPL34 | ribosomal protein L34 | 0.0221624 |
| MT1E | metallothionein 1E | 0.0216486 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0215978 |
| RPL30 | ribosomal protein L30 | 0.0214936 |
| AHI1 | Abelson helper integration site 1 | 0.0213918 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0212158 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0201816 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0201629 |
| RPL37 | ribosomal protein L37 | 0.0198371 |
| RPLP1 | ribosomal protein, large, P1 | 0.0197277 |
| BMP4 | bone morphogenetic protein 4 | 0.0194358 |
| CD63 | CD63 molecule | 0.019412 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0189053 |
| RPL9 | ribosomal protein L9 | 0.0187479 |
| CTSB | cathepsin B | 0.0186871 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0186019 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0185523 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0183606 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0179568 |
| CRY1 | cryptochrome circadian clock 1 | 0.0179509 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0177216 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.017708 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0173755 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0172824 |
| RPS25 | ribosomal protein S25 | 0.0172469 |
| LONP1 | lon peptidase 1, mitochondrial | 0.0172039 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0170688 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0170266 |
| MXD1 | MAX dimerization protein 1 | 0.0170196 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0169324 |
| LDHA | lactate dehydrogenase A | 0.0169009 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0168286 |
| CDK13 | cyclin-dependent kinase 13 | 0.016254 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0162256 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0161665 |
| SFTPA2 | surfactant protein A2 | 0.016041 |
| FOXO1 | forkhead box O1 | 0.0157716 |
| SNX9 | sorting nexin 9 | 0.0157702 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0157688 |
| TMC5 | transmembrane channel-like 5 | 0.0157547 |
| GANAB | glucosidase, alpha; neutral AB | 0.0156579 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0155833 |
| MUC3B | mucin 3B, cell surface associated | 0.0155721 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0153631 |
| CYP2S1 | cytochrome P450, family 2, subfamily S, polypeptide 1 | 0.0152776 |
| NUCB2 | nucleobindin 2 | 0.0152745 |
| HM13 | histocompatibility (minor) 13 | 0.0152527 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0151316 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0150197 |
| PDZD8 | PDZ domain containing 8 | 0.0148231 |
| SERINC2 | serine incorporator 2 | 0.0146381 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0146133 |
| TMEM65 | transmembrane protein 65 | 0.0146091 |
| CMIP | c-Maf inducing protein | 0.0145604 |
| RPN1 | ribophorin I | 0.0145276 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0141879 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0141868 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0141503 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0140662 |
| RPS2 | ribosomal protein S2 | 0.0139814 |
| LASP1 | LIM and SH3 protein 1 | 0.0136618 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0136445 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0135877 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0135068 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0134922 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.266678 |
| ITGA6 | integrin, alpha 6 | -0.160958 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.126167 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.12581 |
| PTMA | prothymosin, alpha | -0.118615 |
| AHNAK | AHNAK nucleoprotein | -0.114942 |
| VCL | vinculin | -0.108617 |
| ANXA2 | annexin A2 | -0.0991337 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0982809 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0854261 |
| ASPH | aspartate beta-hydroxylase | -0.0839328 |
| FLNB | filamin B, beta | -0.0816366 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0812848 |
| GPHN | gephyrin | -0.0802901 |
| EZR | ezrin | -0.0783011 |
| TMSB10 | thymosin beta 10 | -0.0768138 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0712341 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0697005 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0693812 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0692892 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0685055 |
| LAMA4 | laminin, alpha 4 | -0.066819 |
| PRELID2 | PRELI domain containing 2 | -0.065324 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0638433 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0611628 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0607657 |
| DENND1A | DENN/MADD domain containing 1A | -0.0599314 |
| KRT18 | keratin 18, type I | -0.0574286 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0569107 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0568758 |
| DSPP | dentin sialophosphoprotein | -0.0567963 |
| ACTN4 | actinin, alpha 4 | -0.0557493 |
| FAM13A | family with sequence similarity 13, member A | -0.0553332 |
| VMP1 | vacuole membrane protein 1 | -0.0552887 |
| SLC35F3 | solute carrier family 35, member F3 | -0.05467 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.054129 |
| FHIT | fragile histidine triad | -0.0538189 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0527281 |
| MED13L | mediator complex subunit 13-like | -0.0521676 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0516629 |
| TNS4 | tensin 4 | -0.0499979 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0489258 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0482571 |
| ECT2 | epithelial cell transforming 2 | -0.0472995 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0456948 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.045459 |
| RNF217 | ring finger protein 217 | -0.0454174 |
| CALB1 | calbindin 1, 28kDa | -0.0451604 |
| CCNY | cyclin Y | -0.0451502 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0450156 |
| SBF2 | SET binding factor 2 | -0.0446896 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0433162 |
| NRXN3 | neurexin 3 | -0.0432352 |
| TXNIP | thioredoxin interacting protein | -0.0431633 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0427473 |
| MLEC | malectin | -0.0427248 |
| NDRG1 | N-myc downstream regulated 1 | -0.0426956 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.042303 |
| CENPF | centromere protein F, 350/400kDa | -0.0418215 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0417757 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0413701 |
| SERINC5 | serine incorporator 5 | -0.04117 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0408764 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0404845 |
| EHBP1 | EH domain binding protein 1 | -0.0395037 |
| KRT8 | keratin 8, type II | -0.0394931 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0394792 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0388021 |
| ENO1 | enolase 1, (alpha) | -0.0385872 |
| DIAPH3 | diaphanous-related formin 3 | -0.0384891 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0382665 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0375338 |
| EPCAM | epithelial cell adhesion molecule | -0.0371782 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0369919 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0366337 |
| ZNF292 | zinc finger protein 292 | -0.0365508 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0361521 |
| SETD5 | SET domain containing 5 | -0.0360471 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0357651 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0356211 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0352823 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0351128 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0350509 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0348466 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0347444 |
| YBX1 | Y box binding protein 1 | -0.0345162 |
| CADPS | Ca++-dependent secretion activator | -0.0341598 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0341489 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0333378 |
| DIAPH2 | diaphanous-related formin 2 | -0.0332148 |
| MYO1D | myosin ID | -0.0327809 |
| RAD51B | RAD51 paralog B | -0.0327077 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0326719 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0325455 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0323523 |
| RNF43 | ring finger protein 43 | -0.0322623 |
| POTEF | POTE ankyrin domain family, member F | -0.0321238 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0315436 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0313754 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0311745 |
