| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | OTS514 perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the OTS514_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.196623 |
| CAPRIN2 | caprin family member 2 | 0.0878577 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0846412 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0739134 |
| HMGA1 | high mobility group AT-hook 1 | 0.0734052 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0704376 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0605912 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0556334 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0550601 |
| MT1E | metallothionein 1E | 0.0547151 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0472233 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0470898 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0458582 |
| CCNL1 | cyclin L1 | 0.0428708 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0414778 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0405854 |
| RPS6 | ribosomal protein S6 | 0.0399873 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0361074 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.035632 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0344628 |
| TMEM41B | transmembrane protein 41B | 0.0321025 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0313624 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0312236 |
| CALU | calumenin | 0.0301588 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0293232 |
| MT2A | metallothionein 2A | 0.028097 |
| PODXL | podocalyxin-like | 0.0280237 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0279617 |
| SEC24A | SEC24 family member A | 0.0271261 |
| RPL37A | ribosomal protein L37a | 0.0258674 |
| MT1X | metallothionein 1X | 0.025855 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0254482 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0250688 |
| TXNRD1 | thioredoxin reductase 1 | 0.0248334 |
| PXDN | peroxidasin | 0.0243521 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0243295 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0239018 |
| EGR1 | early growth response 1 | 0.0236897 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0236311 |
| USP12 | ubiquitin specific peptidase 12 | 0.0224871 |
| RPL23 | ribosomal protein L23 | 0.0224798 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0218574 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0214016 |
| RTN4 | reticulon 4 | 0.021144 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0211068 |
| COPA | coatomer protein complex, subunit alpha | 0.0210526 |
| RPL27 | ribosomal protein L27 | 0.0209003 |
| TXNIP | thioredoxin interacting protein | 0.0208236 |
| TUBB6 | tubulin, beta 6 class V | 0.0207869 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0207602 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0206073 |
| CALR | calreticulin | 0.0205574 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0202716 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0202182 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0197432 |
| RPL37 | ribosomal protein L37 | 0.0196863 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0194361 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0193376 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0192517 |
| ANGPTL4 | angiopoietin-like 4 | 0.0190875 |
| RPS12 | ribosomal protein S12 | 0.0190719 |
| RAI1 | retinoic acid induced 1 | 0.0189144 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.018746 |
| RPL9 | ribosomal protein L9 | 0.0187338 |
| LOXL2 | lysyl oxidase-like 2 | 0.0186405 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.018627 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0186158 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0184919 |
| LDHA | lactate dehydrogenase A | 0.0183066 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0180249 |
| TGM2 | transglutaminase 2 | 0.0178291 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0177763 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0176898 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0176598 |
| RPS25 | ribosomal protein S25 | 0.0175865 |
| RPL35A | ribosomal protein L35a | 0.0175841 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0175802 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0174078 |
| FOSL1 | FOS-like antigen 1 | 0.0173018 |
| RPL4 | ribosomal protein L4 | 0.0171067 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0169295 |
| RPL36 | ribosomal protein L36 | 0.0166099 |
| RPS13 | ribosomal protein S13 | 0.0162351 |
| RPL30 | ribosomal protein L30 | 0.0158496 |
| SFTPA2 | surfactant protein A2 | 0.0155556 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0151699 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0150189 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0149677 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0149114 |
| RPL36A | ribosomal protein L36a | 0.0148714 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0148484 |
| CD68 | CD68 molecule | 0.0146106 |
| PGM3 | phosphoglucomutase 3 | 0.0146083 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0145935 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.01425 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0142123 |
| RPS27 | ribosomal protein S27 | 0.0141072 |
| USP36 | ubiquitin specific peptidase 36 | 0.0140627 |
| PCDH1 | protocadherin 1 | 0.0139292 |
| BARX2 | BARX homeobox 2 | 0.0139191 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TP63 | tumor protein p63 | -0.148307 |
| TMSB4X | thymosin beta 4, X-linked | -0.117599 |
| PTMA | prothymosin, alpha | -0.112727 |
| TMSB10 | thymosin beta 10 | -0.111281 |
| VIM | vimentin | -0.105803 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0967924 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0924776 |
| RAD51B | RAD51 paralog B | -0.0896265 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.073655 |
| EHBP1 | EH domain binding protein 1 | -0.0680756 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0673572 |
| FMNL2 | formin-like 2 | -0.0627586 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0619192 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.061117 |
| EXOC4 | exocyst complex component 4 | -0.0585179 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0580645 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0573207 |
| CADM2 | cell adhesion molecule 2 | -0.0561344 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0500196 |
| RIGI | RNA sensor RIG-I | -0.0497374 |
| DST | dystonin | -0.0483712 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0479048 |
| TNS3 | tensin 3 | -0.047331 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0471802 |
| AHNAK | AHNAK nucleoprotein | -0.0460979 |
| PRELID2 | PRELI domain containing 2 | -0.0458514 |
| DPH6 | diphthamine biosynthesis 6 | -0.0454436 |
| ZNF217 | zinc finger protein 217 | -0.0449378 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0420222 |
| CD44 | CD44 molecule (Indian blood group) | -0.041341 |
| PTK2 | protein tyrosine kinase 2 | -0.0413024 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0411252 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0397735 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0394414 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0390929 |
| VCL | vinculin | -0.0390839 |
| ZNF292 | zinc finger protein 292 | -0.0390148 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0390007 |
| PARD3 | par-3 family cell polarity regulator | -0.0387067 |
| RNF213 | ring finger protein 213 | -0.0381746 |
| CENPF | centromere protein F, 350/400kDa | -0.0374404 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0373964 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0373893 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0372741 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0371456 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0351549 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0347231 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0345572 |
| DIAPH3 | diaphanous-related formin 3 | -0.0343399 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0337951 |
| SRGN | serglycin | -0.0336857 |
| NEK10 | NIMA-related kinase 10 | -0.0329938 |
| OGA | O-GlcNAcase | -0.0329477 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0327924 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.032279 |
| HDAC9 | histone deacetylase 9 | -0.0321165 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0320172 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0319042 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0317959 |
| CANX | calnexin | -0.0315903 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0314299 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0312299 |
| RBM39 | RNA binding motif protein 39 | -0.0306403 |
| APP | amyloid beta (A4) precursor protein | -0.0303918 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0302885 |
| NF1 | neurofibromin 1 | -0.0296487 |
| CDK6 | cyclin-dependent kinase 6 | -0.0295023 |
| DENND1A | DENN/MADD domain containing 1A | -0.02931 |
| RBM25 | RNA binding motif protein 25 | -0.0291256 |
| H1-0 | H1.0 linker histone | -0.0290386 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0290066 |
| YBX1 | Y box binding protein 1 | -0.0289111 |
| SMAD3 | SMAD family member 3 | -0.0286869 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0285985 |
| SP100 | SP100 nuclear antigen | -0.0284187 |
| COL5A2 | collagen, type V, alpha 2 | -0.0283999 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0282065 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0278139 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0277524 |
| SEPTIN7 | septin 7 | -0.0276325 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0274773 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.027264 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0271723 |
| XPO1 | exportin 1 | -0.0269119 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0269031 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0267874 |
| STAG2 | stromal antigen 2 | -0.0264302 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0262553 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0261965 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0260153 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0258898 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0256768 |
| MATR3 | matrin 3 | -0.0255219 |
| ECE1 | endothelin converting enzyme 1 | -0.0252253 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0250268 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.02502 |
| ECT2 | epithelial cell transforming 2 | -0.0249011 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0246698 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0246199 |
| ANLN | anillin, actin binding protein | -0.0245557 |
