| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | OTS514 perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the OTS514_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SDK1 | sidekick cell adhesion molecule 1 | 0.106836 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.101554 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0851579 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0849569 |
| NAV2 | neuron navigator 2 | 0.0831996 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.075123 |
| CDH13 | cadherin 13 | 0.0750378 |
| IFI44L | interferon-induced protein 44-like | 0.0647095 |
| NRP1 | neuropilin 1 | 0.0640052 |
| GLCCI1 | glucocorticoid induced 1 | 0.0632995 |
| MTSS1 | metastasis suppressor 1 | 0.0588114 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0550781 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.05456 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0514091 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0509712 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0477525 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0467442 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0463628 |
| HMGA2 | high mobility group AT-hook 2 | 0.0458856 |
| SMAD3 | SMAD family member 3 | 0.0442468 |
| FAM20C | family with sequence similarity 20, member C | 0.0407195 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0406508 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0403071 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.039819 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0395153 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0380993 |
| EFNA5 | ephrin-A5 | 0.0380179 |
| PTK2 | protein tyrosine kinase 2 | 0.0369196 |
| INTS6 | integrator complex subunit 6 | 0.0366281 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0364486 |
| ANXA10 | annexin A10 | 0.0350838 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0346426 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0345345 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0341102 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0334163 |
| SEPTIN9 | septin 9 | 0.0331967 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0329582 |
| CLMP | CXADR-like membrane protein | 0.0319048 |
| LDHA | lactate dehydrogenase A | 0.0318943 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0314527 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0313518 |
| PKM | pyruvate kinase, muscle | 0.0310973 |
| LOX | lysyl oxidase | 0.0307851 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0304044 |
| LOXL2 | lysyl oxidase-like 2 | 0.0302288 |
| ZNF638 | zinc finger protein 638 | 0.0295967 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0294899 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0294711 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0293195 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.028807 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0282623 |
| NHSL1 | NHS-like 1 | 0.028092 |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.0276888 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0275202 |
| EGFR | epidermal growth factor receptor | 0.0272672 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0272484 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0270592 |
| ASPH | aspartate beta-hydroxylase | 0.0269199 |
| PODXL | podocalyxin-like | 0.0268252 |
| WLS | wntless Wnt ligand secretion mediator | 0.0256498 |
| HMGA1 | high mobility group AT-hook 1 | 0.0255984 |
| SVIL | supervillin | 0.0253631 |
| PRKCA | protein kinase C, alpha | 0.0253113 |
| ZFHX3 | zinc finger homeobox 3 | 0.0252487 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0250651 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0249079 |
| ZNF804A | zinc finger protein 804A | 0.0242759 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0241952 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0236376 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0233706 |
| TRIOBP | TRIO and F-actin binding protein | 0.0230052 |
| RARB | retinoic acid receptor, beta | 0.0229891 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0224458 |
| CTBP2 | C-terminal binding protein 2 | 0.0222142 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0221019 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0220665 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0220408 |
| TGM2 | transglutaminase 2 | 0.0217894 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0217264 |
| ATF7 | activating transcription factor 7 | 0.0216536 |
| RASAL2 | RAS protein activator like 2 | 0.021488 |
| NRG1 | neuregulin 1 | 0.0214344 |
| NLK | nemo-like kinase | 0.0214343 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0213899 |
| TRIM25 | tripartite motif containing 25 | 0.0213451 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0212491 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0212307 |
| CUX1 | cut-like homeobox 1 | 0.0212137 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0211718 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0211451 |
| HDAC4 | histone deacetylase 4 | 0.020919 |
| ARHGAP17 | Rho GTPase activating protein 17 | 0.0207016 |
| RNF213 | ring finger protein 213 | 0.0205022 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0203203 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0201583 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0201238 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0200561 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0199347 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0199005 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0198324 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.191135 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.14652 |
| TMSB10 | thymosin beta 10 | -0.118161 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0868183 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0852779 |
| RBM39 | RNA binding motif protein 39 | -0.0818904 |
| VIM | vimentin | -0.0805398 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0794775 |
| GOLGA4 | golgin A4 | -0.0729392 |
| CD44 | CD44 molecule (Indian blood group) | -0.0725798 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0723156 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0694051 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0683846 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.068282 |
| PTMA | prothymosin, alpha | -0.0618097 |
| EGR1 | early growth response 1 | -0.0617228 |
| IER3 | immediate early response 3 | -0.0614855 |
| FTL | ferritin, light polypeptide | -0.0603485 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0597118 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0512599 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0510776 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0496023 |
| CANX | calnexin | -0.0490177 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0488795 |
| SYAP1 | synapse associated protein 1 | -0.0478175 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0473385 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0457664 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0445548 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0444028 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0439703 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0436312 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0432984 |
| OGA | O-GlcNAcase | -0.0430587 |
| FAM13A | family with sequence similarity 13, member A | -0.0418475 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0403509 |
| OSMR | oncostatin M receptor | -0.039682 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0388566 |
| KYNU | kynureninase | -0.0388145 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0387153 |
| SPAG9 | sperm associated antigen 9 | -0.0385139 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0378881 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0371536 |
| TNNC1 | troponin C type 1 (slow) | -0.0367081 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0353059 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0349129 |
| SBF2 | SET binding factor 2 | -0.0348003 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0337835 |
| VCL | vinculin | -0.0324982 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0322821 |
| YME1L1 | YME1-like 1 ATPase | -0.0319124 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0317036 |
| RIOK3 | RIO kinase 3 | -0.0316993 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0315477 |
| TMSB4X | thymosin beta 4, X-linked | -0.0309928 |
| S100A10 | S100 calcium binding protein A10 | -0.030775 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0305164 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0295068 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.0290366 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0289356 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.028648 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0276976 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0276936 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0276683 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0275829 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0269796 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0268933 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0266713 |
| ARF4 | ADP-ribosylation factor 4 | -0.026351 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0261243 |
| ETV6 | ets variant 6 | -0.0252422 |
| VMP1 | vacuole membrane protein 1 | -0.0248979 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0247676 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0246558 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | -0.024484 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0244513 |
| KLF6 | Kruppel-like factor 6 | -0.0242456 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0241351 |
| PRKCSH | protein kinase C substrate 80K-H | -0.0239531 |
| ABI1 | abl-interactor 1 | -0.0239281 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0237375 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0236491 |
| WDR45B | WD repeat domain 45B | -0.0234517 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0233903 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0233036 |
| TMEM87A | transmembrane protein 87A | -0.023265 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0232608 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0231759 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0229804 |
| ATP13A3 | ATPase type 13A3 | -0.0229479 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.022941 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0228481 |
| TPM4 | tropomyosin 4 | -0.0228066 |
| CDK17 | cyclin-dependent kinase 17 | -0.0225683 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0224379 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0222499 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0221541 |
| EZR | ezrin | -0.0221442 |
| AHNAK | AHNAK nucleoprotein | -0.0218115 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0217254 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0215367 |
