| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | OTS514 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the OTS514_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.139939 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.139642 |
| FAM13A | family with sequence similarity 13, member A | 0.0770212 |
| NDRG1 | N-myc downstream regulated 1 | 0.0763291 |
| ARRDC3 | arrestin domain containing 3 | 0.0737744 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0680835 |
| ADM | adrenomedullin | 0.0619854 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0604524 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0604175 |
| CADM1 | cell adhesion molecule 1 | 0.0574495 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0475569 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0472469 |
| PKM | pyruvate kinase, muscle | 0.0466343 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0465071 |
| SETD5 | SET domain containing 5 | 0.0459069 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0447803 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0429634 |
| MT1X | metallothionein 1X | 0.0415667 |
| RNF145 | ring finger protein 145 | 0.0396134 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0388905 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0387004 |
| ZNF292 | zinc finger protein 292 | 0.0380866 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0374113 |
| H3-3B | H3.3 histone B | 0.0365871 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0357096 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0344572 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0342378 |
| SDC4 | syndecan 4 | 0.0341659 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0331758 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0326711 |
| ZNF207 | zinc finger protein 207 | 0.0318796 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0315651 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0314119 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0312025 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0307116 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0307065 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0304197 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0292296 |
| RBM39 | RNA binding motif protein 39 | 0.0292244 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0289093 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0282154 |
| HPCAL1 | hippocalcin-like 1 | 0.0281006 |
| C1D | C1D nuclear receptor corepressor | 0.0277378 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0276859 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0273064 |
| RPS6 | ribosomal protein S6 | 0.0270719 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0267099 |
| SEPTIN9 | septin 9 | 0.0266766 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0265576 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0265025 |
| MANBA | mannosidase, beta A, lysosomal | 0.0264877 |
| ACTN1 | actinin, alpha 1 | 0.0263847 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.026375 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.025968 |
| S100A9 | S100 calcium binding protein A9 | 0.025928 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0259099 |
| ZNF395 | zinc finger protein 395 | 0.0254345 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0253293 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0250211 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0247475 |
| RLF | rearranged L-myc fusion | 0.0243804 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0243795 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0242897 |
| SNX13 | sorting nexin 13 | 0.0242614 |
| XPO1 | exportin 1 | 0.0239637 |
| EXOC1 | exocyst complex component 1 | 0.0237544 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0237429 |
| VEGFA | vascular endothelial growth factor A | 0.0237365 |
| KCTD9 | potassium channel tetramerization domain containing 9 | 0.0234401 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0233941 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0233291 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0232709 |
| GOLGA4 | golgin A4 | 0.0232347 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0229796 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0228995 |
| SYNPO | synaptopodin | 0.0227989 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0225574 |
| AFF4 | AF4/FMR2 family, member 4 | 0.022278 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0222304 |
| CDK7 | cyclin-dependent kinase 7 | 0.0221955 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0221363 |
| PMM2 | phosphomannomutase 2 | 0.0221337 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0219785 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0218024 |
| DSTN | destrin (actin depolymerizing factor) | 0.0217275 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0215399 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0214708 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0211879 |
| TNPO3 | transportin 3 | 0.0207589 |
| RPL36 | ribosomal protein L36 | 0.0206509 |
| POM121C | POM121 transmembrane nucleoporin C | 0.0205784 |
| XPO6 | exportin 6 | 0.0204492 |
| RPL23 | ribosomal protein L23 | 0.0203836 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0203498 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.0202909 |
| CALR | calreticulin | 0.0202104 |
| SEC24B | SEC24 family member B | 0.0201514 |
| COPA | coatomer protein complex, subunit alpha | 0.0200642 |
| USP33 | ubiquitin specific peptidase 33 | 0.0200626 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0198978 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.257456 |
| FN1 | fibronectin 1 | -0.188272 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.162183 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.12856 |
| CDH13 | cadherin 13 | -0.11687 |
| VIM | vimentin | -0.115711 |
| PRSS23 | protease, serine, 23 | -0.0954847 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0945644 |
| NAV1 | neuron navigator 1 | -0.0794622 |
| VCL | vinculin | -0.0765206 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0706893 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0703035 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0681364 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0679472 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0644914 |
| COL1A2 | collagen, type I, alpha 2 | -0.064137 |
| ASPH | aspartate beta-hydroxylase | -0.0618427 |
| LOX | lysyl oxidase | -0.060726 |
| AHNAK | AHNAK nucleoprotein | -0.0606512 |
| STC1 | stanniocalcin 1 | -0.0579665 |
| CD44 | CD44 molecule (Indian blood group) | -0.0560302 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0558813 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0558734 |
| COL1A1 | collagen, type I, alpha 1 | -0.0535708 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0527318 |
| RAI14 | retinoic acid induced 14 | -0.0526108 |
| ACTG1 | actin gamma 1 | -0.0505446 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0488732 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0488534 |
| COL5A1 | collagen, type V, alpha 1 | -0.0461428 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0447553 |
| ENO1 | enolase 1, (alpha) | -0.0436528 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0434736 |
| TMSB10 | thymosin beta 10 | -0.041024 |
| DST | dystonin | -0.040296 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0394681 |
| GLIS3 | GLIS family zinc finger 3 | -0.0380441 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0376035 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0374736 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0373489 |
| UTRN | utrophin | -0.0371653 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0369966 |
| TPM4 | tropomyosin 4 | -0.0366206 |
| RASAL2 | RAS protein activator like 2 | -0.0361302 |
| CALU | calumenin | -0.0358344 |
| MAP1B | microtubule-associated protein 1B | -0.0356144 |
| KYNU | kynureninase | -0.0350664 |
| HLA-C | major histocompatibility complex, class I, C | -0.034898 |
| MAP4 | microtubule-associated protein 4 | -0.0338886 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.033833 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0334026 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0333 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0327757 |
| VEGFC | vascular endothelial growth factor C | -0.0316743 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0313761 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0313633 |
| HMGA2 | high mobility group AT-hook 2 | -0.0310939 |
| TNS3 | tensin 3 | -0.0307236 |
| LAMB3 | laminin, beta 3 | -0.0306315 |
| HDLBP | high density lipoprotein binding protein | -0.0303202 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0302955 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0298816 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.029862 |
| RRBP1 | ribosome binding protein 1 | -0.0297153 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0296454 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0285985 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0284282 |
| PTMA | prothymosin, alpha | -0.0282233 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0273209 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0270441 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0269867 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0269313 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0266952 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0262363 |
| OXR1 | oxidation resistance 1 | -0.0261114 |
| PCYOX1 | prenylcysteine oxidase 1 | -0.0259339 |
| NABP1 | nucleic acid binding protein 1 | -0.0256769 |
| TMSB4X | thymosin beta 4, X-linked | -0.0254835 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0254155 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0253322 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0253013 |
| CALD1 | caldesmon 1 | -0.0252724 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0251414 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0248422 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0248421 |
| ATG7 | autophagy related 7 | -0.02481 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0247442 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0243983 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0241544 |
| MKI67 | marker of proliferation Ki-67 | -0.0241196 |
| ROS1 | ROS proto-oncogene 1 , receptor tyrosine kinase | -0.023836 |
| SERINC3 | serine incorporator 3 | -0.0235038 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0234549 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0233949 |
| TUBA1B | tubulin, alpha 1b | -0.0233488 |
| TPM1 | tropomyosin 1 (alpha) | -0.0232237 |
| FBN1 | fibrillin 1 | -0.0225087 |
| ATXN1 | ataxin 1 | -0.0225077 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0225006 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0222661 |
