| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | OTS514 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the OTS514_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | 0.0772819 |
| SMYD3 | SET and MYND domain containing 3 | 0.0465116 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.046472 |
| SMAD3 | SMAD family member 3 | 0.0440311 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0425377 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0413455 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0410976 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0410883 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0397538 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0366186 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0352289 |
| PRKCA | protein kinase C, alpha | 0.0332867 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0328371 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0326055 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0321934 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0321263 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0314282 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0313513 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0311911 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0306405 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0306372 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0298086 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0294705 |
| PCNX4 | pecanex 4 | 0.0292887 |
| CCNL1 | cyclin L1 | 0.0288497 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0286765 |
| NUP98 | nucleoporin 98kDa | 0.0270296 |
| FLNA | filamin A, alpha | 0.0266651 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.024437 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0243444 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0237869 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.023718 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0234592 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0229583 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0228561 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0228539 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.022667 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0225327 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0225082 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0223638 |
| SCGB2B2 | secretoglobin, family 2B, member 2 | 0.0222983 |
| OXSR1 | oxidative stress responsive 1 | 0.02217 |
| PKM | pyruvate kinase, muscle | 0.0219611 |
| FOSL1 | FOS-like antigen 1 | 0.0219084 |
| NUP153 | nucleoporin 153kDa | 0.0218206 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0216719 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0216372 |
| AEBP2 | AE binding protein 2 | 0.0216331 |
| RORA | RAR-related orphan receptor A | 0.0215641 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0215128 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0214812 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.021169 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0210042 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0207752 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0205985 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0204819 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0204165 |
| DENND4A | DENN/MADD domain containing 4A | 0.02014 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0199466 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0198258 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0197895 |
| DENND5A | DENN/MADD domain containing 5A | 0.0197035 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0196483 |
| SELENOI | selenoprotein I | 0.0196423 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.019519 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.0194999 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0193936 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0192691 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0192371 |
| CDK6 | cyclin-dependent kinase 6 | 0.0192045 |
| SIK2 | salt-inducible kinase 2 | 0.0191765 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0191458 |
| UST | uronyl-2-sulfotransferase | 0.0190993 |
| FOXN3 | forkhead box N3 | 0.0188826 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0188274 |
| KLF10 | Kruppel-like factor 10 | 0.0188121 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0187278 |
| PLD3 | phospholipase D family, member 3 | 0.018513 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0184973 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0184547 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0184181 |
| RUNX1 | runt-related transcription factor 1 | 0.0183604 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0178968 |
| ARL17B | ADP-ribosylation factor-like 17B | 0.0178925 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0178844 |
| MAP2K3 | mitogen-activated protein kinase kinase 3 | 0.0178292 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | 0.0177633 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0177201 |
| KIF1B | kinesin family member 1B | 0.017649 |
| GPHN | gephyrin | 0.0175491 |
| SF1 | splicing factor 1 | 0.017541 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0175285 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | 0.0175222 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0174944 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0174086 |
| MCU | mitochondrial calcium uniporter | 0.0173495 |
| FBXO38 | F-box protein 38 | 0.0173114 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0172818 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.0172572 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0172301 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.178858 |
| TMSB10 | thymosin beta 10 | -0.138236 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.111952 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0720336 |
| PTMA | prothymosin, alpha | -0.0674262 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0632304 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0625154 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0588792 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0556627 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.055168 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0548158 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0543719 |
| DST | dystonin | -0.0541444 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0534517 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0527499 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0507631 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0501631 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0462957 |
| ANGPTL4 | angiopoietin-like 4 | -0.0455982 |
| DNER | delta/notch-like EGF repeat containing | -0.0439475 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0420994 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0411294 |
| AHNAK | AHNAK nucleoprotein | -0.0410674 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0410076 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0395259 |
| MT2A | metallothionein 2A | -0.0395181 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.039331 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0393051 |
| TPM4 | tropomyosin 4 | -0.0392409 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0386509 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0385841 |
| NAV2 | neuron navigator 2 | -0.0374617 |
| SDC4 | syndecan 4 | -0.0372539 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0372057 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0365559 |
| RIGI | RNA sensor RIG-I | -0.0362968 |
| RBM39 | RNA binding motif protein 39 | -0.0359986 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0355372 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0353567 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0349912 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.034984 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0348735 |
| RPLP1 | ribosomal protein, large, P1 | -0.034801 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0347384 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0341557 |
| ANKRD11 | ankyrin repeat domain 11 | -0.033692 |
| NGLY1 | N-glycanase 1 | -0.0336791 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0324487 |
| RPL12 | ribosomal protein L12 | -0.0318314 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0315731 |
| SEPTIN7 | septin 7 | -0.0314114 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0308646 |
| IER3 | immediate early response 3 | -0.0305666 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0305314 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0303621 |
| ERBIN | erbb2 interacting protein | -0.0301699 |
| SBF2 | SET binding factor 2 | -0.0299469 |
| CEP170 | centrosomal protein 170kDa | -0.0290605 |
| FMN1 | formin 1 | -0.0289403 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.028838 |
| HLA-C | major histocompatibility complex, class I, C | -0.0286617 |
| FER | fer (fps/fes related) tyrosine kinase | -0.028364 |
| MAP4 | microtubule-associated protein 4 | -0.0282746 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0280364 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0279253 |
| KIF5B | kinesin family member 5B | -0.0279185 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0277808 |
| RIN2 | Ras and Rab interactor 2 | -0.0276369 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0271486 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0271219 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0265455 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0263129 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0260103 |
| LMO7 | LIM domain 7 | -0.0257834 |
| SVIL | supervillin | -0.0257399 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0255329 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0252262 |
| RAD51B | RAD51 paralog B | -0.0251588 |
| GPC6 | glypican 6 | -0.0249951 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0248435 |
| UBB | ubiquitin B | -0.0248087 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0247603 |
| RPL26 | ribosomal protein L26 | -0.0247543 |
| CD44 | CD44 molecule (Indian blood group) | -0.0245394 |
| SPAG9 | sperm associated antigen 9 | -0.0244468 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0244286 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0244028 |
| KLF6 | Kruppel-like factor 6 | -0.0242428 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0241159 |
| ASPH | aspartate beta-hydroxylase | -0.0240868 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0239254 |
| FLNB | filamin B, beta | -0.0236675 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0233438 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0232107 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0229417 |
| USP3 | ubiquitin specific peptidase 3 | -0.0226848 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0226761 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0226618 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0221365 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0218183 |
