| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | OTS514 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the OTS514_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0508991 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0454403 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0446125 |
| CD109 | CD109 molecule | 0.0433223 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0404209 |
| OSMR | oncostatin M receptor | 0.0400404 |
| FLNA | filamin A, alpha | 0.0379586 |
| NRP1 | neuropilin 1 | 0.0370737 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0350094 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0341211 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0333702 |
| SMAD3 | SMAD family member 3 | 0.032741 |
| TMEM156 | transmembrane protein 156 | 0.0321134 |
| CAB39 | calcium binding protein 39 | 0.0317354 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0312624 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0312244 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0306913 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0294255 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0287759 |
| RTN4 | reticulon 4 | 0.0274409 |
| SMYD3 | SET and MYND domain containing 3 | 0.0273505 |
| FAT1 | FAT atypical cadherin 1 | 0.0270462 |
| ITGB5 | integrin, beta 5 | 0.0269876 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.026833 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0245975 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0243706 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0242938 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0239039 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0233249 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0233077 |
| CCNL1 | cyclin L1 | 0.0230652 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.022755 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.021942 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0218627 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0216716 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0213495 |
| PELO | pelota homolog (Drosophila) | 0.0210774 |
| CD44 | CD44 molecule (Indian blood group) | 0.0210636 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0209451 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0206893 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0206471 |
| MEF2D | myocyte enhancer factor 2D | 0.0203788 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0201736 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0200148 |
| ETNK1 | ethanolamine kinase 1 | 0.019991 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0199284 |
| RUNX1 | runt-related transcription factor 1 | 0.0198182 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.019692 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0194258 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0192446 |
| FOSL2 | FOS-like antigen 2 | 0.0190516 |
| PKM | pyruvate kinase, muscle | 0.0189889 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0189695 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0189387 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0189315 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0187036 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0186843 |
| SVIL | supervillin | 0.0183174 |
| OGA | O-GlcNAcase | 0.0182255 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0182231 |
| USP22 | ubiquitin specific peptidase 22 | 0.0180041 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0177258 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0176565 |
| EGFR | epidermal growth factor receptor | 0.0176113 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0174662 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0173939 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0173301 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0172587 |
| CUL3 | cullin 3 | 0.0170542 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0170194 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0169055 |
| WDR26 | WD repeat domain 26 | 0.0167726 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0166346 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0163975 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0163873 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | 0.0163717 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0161952 |
| CEP95 | centrosomal protein 95kDa | 0.01619 |
| SMOX | spermine oxidase | 0.0161205 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0160703 |
| IL6ST | interleukin 6 signal transducer | 0.0160355 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0159256 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0159211 |
| RBM25 | RNA binding motif protein 25 | 0.0155774 |
| SF1 | splicing factor 1 | 0.0155188 |
| TGM2 | transglutaminase 2 | 0.0153658 |
| ZFR | zinc finger RNA binding protein | 0.0153165 |
| ARRDC3 | arrestin domain containing 3 | 0.0152449 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0151912 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0151471 |
| ATP13A3 | ATPase type 13A3 | 0.0151118 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0151086 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0149402 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0149013 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0148703 |
| ERBIN | erbb2 interacting protein | 0.0148364 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0148042 |
| FRYL | FRY-like | 0.0147701 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0146285 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0146176 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.22761 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.19967 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.181257 |
| FN1 | fibronectin 1 | -0.172197 |
| PTMA | prothymosin, alpha | -0.139503 |
| TMSB10 | thymosin beta 10 | -0.106089 |
| SQSTM1 | sequestosome 1 | -0.104413 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.102575 |
| HMGA2 | high mobility group AT-hook 2 | -0.100207 |
| CANX | calnexin | -0.0968852 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0950292 |
| FTL | ferritin, light polypeptide | -0.0912316 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0732231 |
| TMSB4X | thymosin beta 4, X-linked | -0.0718758 |
| RAI14 | retinoic acid induced 14 | -0.058402 |
| VCL | vinculin | -0.0575038 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0538998 |
| PLIN2 | perilipin 2 | -0.0514959 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0508106 |
| S100A6 | S100 calcium binding protein A6 | -0.050122 |
| SYT1 | synaptotagmin I | -0.0479209 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0476589 |
| INTS6 | integrator complex subunit 6 | -0.0476546 |
| VIM | vimentin | -0.0472838 |
| HLA-B | major histocompatibility complex, class I, B | -0.0466072 |
| NDRG1 | N-myc downstream regulated 1 | -0.0460725 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0447764 |
| AEBP2 | AE binding protein 2 | -0.0429753 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0409713 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0399954 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0394479 |
| ASPH | aspartate beta-hydroxylase | -0.0393757 |
| B2M | beta-2-microglobulin | -0.036851 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0366061 |
| LMNA | lamin A/C | -0.0363088 |
| ENO1 | enolase 1, (alpha) | -0.0363051 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0362748 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0362602 |
| IER3 | immediate early response 3 | -0.0356239 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0349704 |
| LRRC23 | leucine rich repeat containing 23 | -0.0342806 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0335964 |
| RPL31 | ribosomal protein L31 | -0.0334711 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0326775 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.03205 |
| CADM1 | cell adhesion molecule 1 | -0.0319027 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0318648 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0300336 |
| ITGA1 | integrin, alpha 1 | -0.0296307 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0295704 |
| TENM4 | teneurin transmembrane protein 4 | -0.0294953 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0294298 |
| S100A10 | S100 calcium binding protein A10 | -0.0290209 |
| AHNAK | AHNAK nucleoprotein | -0.028993 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0286573 |
| TXNIP | thioredoxin interacting protein | -0.0282931 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0277727 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0267316 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0267097 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0260487 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.02571 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0255925 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0248903 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0243393 |
| STC2 | stanniocalcin 2 | -0.0241378 |
| RPS12 | ribosomal protein S12 | -0.0238222 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0235527 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0235421 |
| HLA-A | major histocompatibility complex, class I, A | -0.0233065 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0230891 |
| FBN1 | fibrillin 1 | -0.0221855 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0219802 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0219276 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0218256 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0207875 |
| GOLGB1 | golgin B1 | -0.0205871 |
| RACK1 | receptor for activated C kinase 1 | -0.0204769 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.020427 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0203955 |
| MORF4L2 | mortality factor 4 like 2 | -0.0202075 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0198299 |
| EFNA5 | ephrin-A5 | -0.0196282 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0195807 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0195687 |
| GLUL | glutamate-ammonia ligase | -0.0194822 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0193812 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0192758 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0192605 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0191873 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0191199 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0191003 |
| RPS3 | ribosomal protein S3 | -0.0188335 |
| TPI1 | triosephosphate isomerase 1 | -0.0187774 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0186346 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0185479 |
| RPLP1 | ribosomal protein, large, P1 | -0.0182312 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0180722 |
| MT2A | metallothionein 2A | -0.0180142 |
| CENPF | centromere protein F, 350/400kDa | -0.0179388 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.017812 |
