OTSSP167 Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
Similar Terms
Downloads & Tools

Genes

150 kinases inhibited by the OTSSP167 small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
AURKB aurora kinase B 1.36211
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.36211
BMPR1B bone morphogenetic protein receptor, type IB 1.36211
RET ret proto-oncogene 1.36211
PLK1 polo-like kinase 1 1.36211
ADCK3 aarF domain containing kinase 3 1.36211
EPHA8 EPH receptor A8 1.36211
ULK3 unc-51 like kinase 3 1.36211
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.36211
STK36 serine/threonine kinase 36 1.36211
RIPK4 receptor-interacting serine-threonine kinase 4 1.36211
ULK2 unc-51 like autophagy activating kinase 2 1.35325
EPHB1 EPH receptor B1 1.35325
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 1.35325
TAOK3 TAO kinase 3 1.35325
CSNK1E casein kinase 1, epsilon 1.35325
GRK1 G protein-coupled receptor kinase 1 1.35325
CDKL3 cyclin-dependent kinase-like 3 1.35325
CDK7 cyclin-dependent kinase 7 1.34449
TAOK2 TAO kinase 2 1.34449
ITK IL2-inducible T-cell kinase 1.34449
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 1.34449
HIPK2 homeodomain interacting protein kinase 2 1.34449
EPHA1 EPH receptor A1 1.34449
STK26 serine/threonine protein kinase 26 1.33582
PTK2 protein tyrosine kinase 2 1.33582
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 1.33582
NUAK2 NUAK family, SNF1-like kinase, 2 1.33582
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 1.33582
DCLK3 doublecortin-like kinase 3 1.33582
MAP3K6 mitogen-activated protein kinase kinase kinase 6 1.33582
LCK LCK proto-oncogene, Src family tyrosine kinase 1.32726
ICK intestinal cell (MAK-like) kinase 1.32726
HIPK1 homeodomain interacting protein kinase 1 1.32726
TAOK1 TAO kinase 1 1.32726
LYN LYN proto-oncogene, Src family tyrosine kinase 1.32726
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 1.31878
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.31878
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.31878
MAP3K11 mitogen-activated protein kinase kinase kinase 11 1.31878
CDK11B cyclin-dependent kinase 11B 1.31878
EPHA7 EPH receptor A7 1.31878
ACVR1 activin A receptor, type I 1.3104
BLK BLK proto-oncogene, Src family tyrosine kinase 1.3104
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 1.30212
SIK3 SIK family kinase 3 1.30212
HIPK3 homeodomain interacting protein kinase 3 1.30212
HCK HCK proto-oncogene, Src family tyrosine kinase 1.30212
FGR FGR proto-oncogene, Src family tyrosine kinase 1.30212
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.29393
CDKL5 cyclin-dependent kinase-like 5 1.29393
CDK14 cyclin-dependent kinase 14 1.28583
CDK15 cyclin-dependent kinase 15 1.28583
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.28583
MUSK muscle, skeletal, receptor tyrosine kinase 1.28583
CSNK1A1L casein kinase 1, alpha 1-like 1.28583
YES1 YES proto-oncogene 1, Src family tyrosine kinase 1.28583
EPHA5 EPH receptor A5 1.27782
FES FES proto-oncogene, tyrosine kinase 1.26991
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.26991
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like) 1.26991
CDK8 cyclin-dependent kinase 8 1.26991
ERBB3 erb-b2 receptor tyrosine kinase 3 1.26209
FER fer (fps/fes related) tyrosine kinase 1.26209
SIK1 salt-inducible kinase 1 1.26209
EPHA6 EPH receptor A6 1.25436
TNK2 tyrosine kinase, non-receptor, 2 1.25436
CDK3 cyclin-dependent kinase 3 1.25436
TXK TXK tyrosine kinase 1.25436
EPHB4 EPH receptor B4 1.25436
MAPK7 mitogen-activated protein kinase 7 1.25436
MAPK15 mitogen-activated protein kinase 15 1.24671
SLK STE20-like kinase 1.24671
MINK1 misshapen-like kinase 1 1.23916
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.22432
MAP3K3 mitogen-activated protein kinase kinase kinase 3 1.22432
EPHA2 EPH receptor A2 1.22432
MERTK MER proto-oncogene, tyrosine kinase 1.22432
CDK5 cyclin-dependent kinase 5 1.21703
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 1.20271
CDK11A cyclin-dependent kinase 11A 1.19918
PLK2 polo-like kinase 2 1.19568
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.19568
FYN FYN proto-oncogene, Src family tyrosine kinase 1.19568
MKNK2 MAP kinase interacting serine/threonine kinase 2 1.19568
STK24 serine/threonine kinase 24 1.18873
AAK1 AP2 associated kinase 1 1.18873
ANKK1 ankyrin repeat and kinase domain containing 1 1.18873
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 1.18186
FRK fyn-related Src family tyrosine kinase 1.18186
NUAK1 NUAK family, SNF1-like kinase, 1 1.17508
DDR1 discoidin domain receptor tyrosine kinase 1 1.16838
BMX BMX non-receptor tyrosine kinase 1.16838
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 1.16838
CDK18 cyclin-dependent kinase 18 1.16177
EPHB6 EPH receptor B6 1.15523
CDK2 cyclin-dependent kinase 2 1.15523
CSNK1G3 casein kinase 1, gamma 3 1.1424
SYK spleen tyrosine kinase 1.1424
IRAK1 interleukin-1 receptor-associated kinase 1 1.1424
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 1.1424
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 1.1424
CIT citron rho-interacting serine/threonine kinase 1.1361
GRK7 G protein-coupled receptor kinase 7 1.1361
LATS2 large tumor suppressor kinase 2 1.12988
TLK2 tousled-like kinase 2 1.12988
BMP2K BMP2 inducible kinase 1.11767
CLK4 CDC-like kinase 4 1.11767
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 1.11767
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 1.11167
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 1.10576
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.09992
TNK1 tyrosine kinase, non-receptor, 1 1.09992
ULK1 unc-51 like autophagy activating kinase 1 1.09415
ZAK sterile alpha motif and leucine zipper containing kinase AZK 1.09415
MYLK myosin light chain kinase 1.09129
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) 1.08283
PTK2B protein tyrosine kinase 2 beta 1.08283
MAP3K9 mitogen-activated protein kinase kinase kinase 9 1.0718
DCLK1 doublecortin-like kinase 1 1.05577
LATS1 large tumor suppressor kinase 1 1.05057
FGFR1 fibroblast growth factor receptor 1 1.05057
TBK1 TANK-binding kinase 1 1.03041
TNIK TRAF2 and NCK interacting kinase 1.02553
TEK TEK tyrosine kinase, endothelial 1.02553
MARK3 MAP/microtubule affinity-regulating kinase 3 1.02071
LTK leukocyte receptor tyrosine kinase 1.02071
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.01127
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 1.01127
MELK maternal embryonic leucine zipper kinase 1.00664
GSK3B glycogen synthase kinase 3 beta 0.993117
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 0.993117
HUNK hormonally up-regulated Neu-associated kinase 0.975893
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.967615
ALK anaplastic lymphoma receptor tyrosine kinase 0.959553
EPHB3 EPH receptor B3 0.959553
MYLK4 myosin light chain kinase family, member 4 0.9517
DMPK dystrophia myotonica-protein kinase 0.936602
MYLK2 myosin light chain kinase 2 0.929345
CDK9 cyclin-dependent kinase 9 0.925786
BTK Bruton agammaglobulinemia tyrosine kinase 0.922275
FLT3 fms-related tyrosine kinase 3 0.922275
HIPK4 homeodomain interacting protein kinase 4 0.915387
TEC tec protein tyrosine kinase 0.902136
INSR insulin receptor 0.883492
CSNK1D casein kinase 1, delta 0.866209
STK17A serine/threonine kinase 17a 0.860727
TNNI3K TNNI3 interacting kinase 0.858037
STK35 serine/threonine kinase 35 0.850157
PDPK1 3-phosphoinositide dependent protein kinase 1 0.850157