| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| Description | A homodetic cyclic peptide that has formula C49H66N10O10S2. (Chemical Entities of Biological Interest Ontology, CHEBI_7726) |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/448601 |
| Similar Terms | |
| Downloads & Tools |
200 proteins with high or low expression in Octreotide relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL17A1 | collagen, type XVII, alpha 1 | 1.31 |
| KLHL20 | kelch-like family member 20 | 0.75 |
| BSN | bassoon presynaptic cytomatrix protein | 0.51 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.48 |
| MPV17 | MpV17 mitochondrial inner membrane protein | 0.41 |
| TCEA3 | transcription elongation factor A (SII), 3 | 0.41 |
| FAM110A | family with sequence similarity 110, member A | 0.37 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.35 |
| ABHD14A | abhydrolase domain containing 14A | 0.34 |
| CCDC150 | coiled-coil domain containing 150 | 0.34 |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 | 0.33 |
| C11ORF98 | chromosome 11 open reading frame 98 | 0.33 |
| LYST | lysosomal trafficking regulator | 0.31 |
| INO80D | INO80 complex subunit D | 0.3 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.3 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 | 0.28 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.28 |
| FAM241B | family with sequence similarity 241 member B | 0.28 |
| KCTD6 | potassium channel tetramerization domain containing 6 | 0.28 |
| PPP1R11 | protein phosphatase 1, regulatory (inhibitor) subunit 11 | 0.28 |
| BORCS7 | BLOC-1 related complex subunit 7 | 0.27 |
| PRDM4 | PR domain containing 4 | 0.27 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 0.26 |
| PLCB4 | phospholipase C, beta 4 | 0.26 |
| VWA5A | von Willebrand factor A domain containing 5A | 0.26 |
| HYPK | huntingtin interacting protein K | 0.26 |
| NLGN2 | neuroligin 2 | 0.26 |
| CCNF | cyclin F | 0.26 |
| SET | SET nuclear proto-oncogene | 0.25 |
| PWWP2B | PWWP domain containing 2B | 0.25 |
| SP100 | SP100 nuclear antigen | 0.25 |
| TRAF3IP2 | TRAF3 interacting protein 2 | 0.25 |
| ACTN4 | actinin, alpha 4 | 0.24 |
| NABP2 | nucleic acid binding protein 2 | 0.24 |
| SH2B2 | SH2B adaptor protein 2 | 0.24 |
| DTWD2 | DTW domain containing 2 | 0.24 |
| REXO1 | REX1, RNA exonuclease 1 homolog (S. cerevisiae) | 0.24 |
| ZNF165 | zinc finger protein 165 | 0.23 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.23 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit | 0.23 |
| MDM4 | MDM4, p53 regulator | 0.22 |
| NOVA1 | neuro-oncological ventral antigen 1 | 0.22 |
| SRD5A3 | steroid 5 alpha-reductase 3 | 0.22 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.22 |
| DDTL | D-dopachrome tautomerase-like | 0.22 |
| KCTD2 | potassium channel tetramerization domain containing 2 | 0.21 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.21 |
| ZXDB | zinc finger, X-linked, duplicated B | 0.21 |
| PARPBP | PARP1 binding protein | 0.21 |
| PFDN1 | prefoldin subunit 1 | 0.21 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.21 |
| BRK1 | BRICK1, SCAR/WAVE actin-nucleating complex subunit | 0.21 |
| ZBTB46 | zinc finger and BTB domain containing 46 | 0.2 |
| RHOA | ras homolog family member A | 0.2 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.2 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.2 |
| HSP90AB3P | heat shock protein 90kDa alpha (cytosolic), class B member 3, pseudogene | 0.19 |
| TNNC2 | troponin C type 2 (fast) | 0.19 |
| PRR3 | proline rich 3 | 0.19 |
| WDR60 | WD repeat domain 60 | 0.19 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.19 |
| TLE2 | transducin-like enhancer of split 2 | 0.19 |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) | 0.19 |
| MRAS | muscle RAS oncogene homolog | 0.19 |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.19 |
| ERH | enhancer of rudimentary homolog (Drosophila) | 0.19 |
| GNG5 | guanine nucleotide binding protein (G protein), gamma 5 | 0.19 |
| ZBED8L | ZBED8 like | 0.19 |
| PLA2G4B | phospholipase A2, group IVB (cytosolic) | 0.18 |
| ZBED8 | zinc finger, BED-type containing 8 | 0.18 |
| VMA21 | VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) | 0.18 |
| BANF1 | barrier to autointegration factor 1 | 0.18 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.18 |
| ARL4D | ADP-ribosylation factor-like 4D | 0.18 |
| SELENOW | selenoprotein W | 0.18 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 | 0.18 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.18 |
| STC2 | stanniocalcin 2 | 0.18 |
| ZBTB45 | zinc finger and BTB domain containing 45 | 0.18 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 0.18 |
| FAM135A | family with sequence similarity 135, member A | 0.17 |
| JMJD4 | jumonji domain containing 4 | 0.17 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.17 |
| METAP2 | methionyl aminopeptidase 2 | 0.17 |
| FAM162A | family with sequence similarity 162, member A | 0.17 |
| TMEM200A | transmembrane protein 200A | 0.17 |
| DCLRE1B | DNA cross-link repair 1B | 0.17 |
| CDC42 | cell division cycle 42 | 0.17 |
| ZNF480 | zinc finger protein 480 | 0.17 |
| PRKCQ | protein kinase C, theta | 0.16 |
| EAF2 | ELL associated factor 2 | 0.16 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | 0.16 |
| PITX2 | paired-like homeodomain 2 | 0.16 |
| PCBD2 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 | 0.16 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.16 |
| DNAH6 | dynein, axonemal, heavy chain 6 | 0.16 |
| B9D1 | B9 protein domain 1 | 0.16 |
| NHP2 | NHP2 ribonucleoprotein | 0.16 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.16 |
| ITGA6 | integrin, alpha 6 | 0.16 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZG16B | zymogen granule protein 16B | -11.46 |
| COL7A1 | collagen, type VII, alpha 1 | -2.32 |
| PIP | prolactin-induced protein | -1.88 |
| SBSN | suprabasin | -1.12 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.78 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 | -0.7 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | -0.68 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | -0.59 |
| SMTN | smoothelin | -0.59 |
| PARD6A | par-6 family cell polarity regulator alpha | -0.57 |
| BLOC1S2 | biogenesis of lysosomal organelles complex-1, subunit 2 | -0.57 |
| TTN | titin | -0.52 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.51 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | -0.5 |
| SUSD1 | sushi domain containing 1 | -0.48 |
| RNF19B | ring finger protein 19B | -0.48 |
| IFI30 | interferon, gamma-inducible protein 30 | -0.48 |
| RBL2 | retinoblastoma-like 2 | -0.47 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 | -0.46 |
| ZNF611 | zinc finger protein 611 | -0.43 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.43 |
| ZBED6 | zinc finger, BED-type containing 6 | -0.43 |
| ERCC6 | excision repair cross-complementation group 6 | -0.42 |
| RPP25 | ribonuclease P/MRP 25kDa subunit | -0.41 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | -0.41 |
| EHF | ets homologous factor | -0.41 |
| C9ORF40 | chromosome 9 open reading frame 40 | -0.4 |
| CCDC28A | coiled-coil domain containing 28A | -0.4 |
| ANKRD10 | ankyrin repeat domain 10 | -0.39 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.39 |
| F8 | coagulation factor VIII, procoagulant component | -0.38 |
| HYAL2 | hyaluronoglucosaminidase 2 | -0.37 |
| ZBTB4 | zinc finger and BTB domain containing 4 | -0.37 |
| SPIDR | scaffolding protein involved in DNA repair | -0.37 |
| RGPD2 | RANBP2-like and GRIP domain containing 2 | -0.36 |
| MGMT | O-6-methylguanine-DNA methyltransferase | -0.36 |
| CEP70 | centrosomal protein 70kDa | -0.36 |
| ZC3H6 | zinc finger CCCH-type containing 6 | -0.35 |
| PRPF40B | PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) | -0.34 |
| KLHL17 | kelch-like family member 17 | -0.33 |
| ZNF226 | zinc finger protein 226 | -0.33 |
| SLC35B1 | solute carrier family 35, member B1 | -0.33 |
| SNX33 | sorting nexin 33 | -0.32 |
| MISO1 | mitochondrial inner membrane subdomain organizer 1 | -0.32 |
| AZI2 | 5-azacytidine induced 2 | -0.32 |
| ZNF776 | zinc finger protein 776 | -0.32 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.32 |
| TEN1 | TEN1 CST complex subunit | -0.32 |
| PTK6 | protein tyrosine kinase 6 | -0.32 |
| SH2B3 | SH2B adaptor protein 3 | -0.31 |
| ROGDI | rogdi homolog (Drosophila) | -0.31 |
| STYX | serine/threonine/tyrosine interacting protein | -0.31 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 | -0.31 |
| ZSCAN29 | zinc finger and SCAN domain containing 29 | -0.31 |
| TSPAN6 | tetraspanin 6 | -0.31 |
| BAIAP2 | BAI1-associated protein 2 | -0.31 |
| FCHO1 | FCH domain only 1 | -0.31 |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase | -0.3 |
| TUBAL3 | tubulin, alpha-like 3 | -0.3 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.3 |
| ENDOV | endonuclease V | -0.3 |
| RAB26 | RAB26, member RAS oncogene family | -0.3 |
| C1D | C1D nuclear receptor corepressor | -0.3 |
| ZNF600 | zinc finger protein 600 | -0.29 |
| ZNF724 | zinc finger protein 724 | -0.29 |
| FKBPL | FK506 binding protein like | -0.28 |
| IFFO2 | intermediate filament family orphan 2 | -0.28 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide | -0.28 |
| ABHD15 | abhydrolase domain containing 15 | -0.28 |
| BMP8A | bone morphogenetic protein 8a | -0.28 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.28 |
| HAPLN3 | hyaluronan and proteoglycan link protein 3 | -0.28 |
| CRYBG2 | crystallin beta-gamma domain containing 2 | -0.27 |
| TLE5 | TLE family member 5, transcriptional modulator | -0.27 |
| OSER1 | oxidative stress responsive serine-rich 1 | -0.27 |
| ZNF341 | zinc finger protein 341 | -0.27 |
| PGK2 | phosphoglycerate kinase 2 | -0.27 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | -0.27 |
| VGF | VGF nerve growth factor inducible | -0.27 |
| ARSD | arylsulfatase D | -0.27 |
| KMT2B | lysine (K)-specific methyltransferase 2B | -0.27 |
| S100A14 | S100 calcium binding protein A14 | -0.27 |
| TYSND1 | trypsin domain containing 1 | -0.27 |
| THEMIS2 | thymocyte selection associated family member 2 | -0.27 |
| C1ORF43 | chromosome 1 open reading frame 43 | -0.26 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | -0.26 |
| SZT2 | seizure threshold 2 homolog (mouse) | -0.26 |
| RAET1G | retinoic acid early transcript 1G | -0.26 |
| TRIM39 | tripartite motif containing 39 | -0.26 |
| TATDN2 | TatD DNase domain containing 2 | -0.26 |
| CES2 | carboxylesterase 2 | -0.26 |
| WDR5B | WD repeat domain 5B | -0.26 |
| ARHGEF19 | Rho guanine nucleotide exchange factor (GEF) 19 | -0.26 |
| BLOC1S4 | biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino | -0.26 |
| CCDC110 | coiled-coil domain containing 110 | -0.25 |
| DUS4L | dihydrouridine synthase 4-like (S. cerevisiae) | -0.25 |
| EPHX4 | epoxide hydrolase 4 | -0.25 |
| DPP4 | dipeptidyl-peptidase 4 | -0.25 |
| DCHS1 | dachsous cadherin-related 1 | -0.25 |
| GMCL2 | germ cell-less 2, spermatogenesis associated | -0.25 |
