Oestrogen Receptor Positive Breast Cancer Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C2938924
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Genes

461 genes associated with the disease Oestrogen Receptor Positive Breast Cancer in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACTB actin, beta
ADAM29 ADAM metallopeptidase domain 29
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ADRM1 adhesion regulating molecule 1
AGFG1 ArfGAP with FG repeats 1
AGO2 argonaute RISC catalytic component 2
AGR2 anterior gradient 2
AKR1C1 aldo-keto reductase family 1, member C1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALX3 ALX homeobox 3
ANGPT2 angiopoietin 2
ANKLE2 ankyrin repeat and LEM domain containing 2
ANO1 anoctamin 1, calcium activated chloride channel
AOC3 amine oxidase, copper containing 3
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APP amyloid beta (A4) precursor protein
APRT adenine phosphoribosyltransferase
AQP3 aquaporin 3 (Gill blood group)
AR androgen receptor
AREG amphiregulin
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARSA arylsulfatase A
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASCC1 activating signal cointegrator 1 complex subunit 1
ASPH aspartate beta-hydroxylase
ATM ATM serine/threonine kinase
AURKA aurora kinase A
AXIN1 axin 1
BAG1 BCL2-associated athanogene
BARD1 BRCA1 associated RING domain 1
BAX BCL2-associated X protein
BCAS2 breast carcinoma amplified sequence 2
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BECN1 beclin 1, autophagy related
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP6 bone morphogenetic protein 6
BMP7 bone morphogenetic protein 7
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BTG2 BTG family, member 2
C1ORF64 chromosome 1 open reading frame 64
CA9 carbonic anhydrase IX
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CBFB core-binding factor, beta subunit
CCDC170 coiled-coil domain containing 170
CCDC6 coiled-coil domain containing 6
CCL2 chemokine (C-C motif) ligand 2
CCN1 cellular communication network factor 1
CCND1 cyclin D1
CCNE2 cyclin E2
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CD82 CD82 molecule
CDC20 cell division cycle 20
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK1 cyclin-dependent kinase 1
CDK3 cyclin-dependent kinase 3
CDK4 cyclin-dependent kinase 4
CDK7 cyclin-dependent kinase 7
CDK8 cyclin-dependent kinase 8
CDK9 cyclin-dependent kinase 9
CDKN2A cyclin-dependent kinase inhibitor 2A
CENPA centromere protein A
CENPI centromere protein I
CETP cholesteryl ester transfer protein, plasma
CHEK2 checkpoint kinase 2
CHKA choline kinase alpha
CHP1 calcineurin-like EF-hand protein 1
CHUK conserved helix-loop-helix ubiquitous kinase
CIP2A cellular inhibitor of PP2A
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLOCK clock circadian regulator
COL11A2 collagen, type XI, alpha 2
COL18A1 collagen, type XVIII, alpha 1
COL1A1 collagen, type I, alpha 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
COMT catechol-O-methyltransferase
CPA1 carboxypeptidase A1 (pancreatic)
CRB3 crumbs family member 3
CREBBP CREB binding protein
CRH corticotropin releasing hormone
CRHR1 corticotropin releasing hormone receptor 1
CRHR2 corticotropin releasing hormone receptor 2
CRY2 cryptochrome circadian clock 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSD cathepsin D
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXXC5 CXXC finger protein 5
CYC1 cytochrome c-1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DCAF1 DDB1 and CUL4 associated factor 1
DCTN3 dynactin 3 (p22)
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEK DEK proto-oncogene
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLC1 DLC1 Rho GTPase activating protein
DLX4 distal-less homeobox 4
DNASE1 deoxyribonuclease I
DNER delta/notch-like EGF repeat containing
DPP3 dipeptidyl-peptidase 3
DUSP7 dual specificity phosphatase 7
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
E2F3 E2F transcription factor 3
E2F7 E2F transcription factor 7
E2F8 E2F transcription factor 8
ECT2 epithelial cell transforming 2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4B eukaryotic translation initiation factor 4B
EIF4E eukaryotic translation initiation factor 4E
EMSY EMSY transcriptional repressor, BRCA2 interacting
EPCAM epithelial cell adhesion molecule
EPHB2 EPH receptor B2
EPN3 epsin 3
EPRS1 glutamyl-prolyl-tRNA synthetase 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
EREG epiregulin
ERLIN2 ER lipid raft associated 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESRP1 epithelial splicing regulatory protein 1
ESRRB estrogen-related receptor beta
ESRRG estrogen-related receptor gamma
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F9 coagulation factor IX
FASN fatty acid synthase
FBXL22 F-box and leucine-rich repeat protein 22
FES FES proto-oncogene, tyrosine kinase
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF2 fibroblast growth factor 2 (basic)
FGF7 fibroblast growth factor 7
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FKBPL FK506 binding protein like
FLOT2 flotillin 2
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FOXC1 forkhead box C1
FOXM1 forkhead box M1
FOXP3 forkhead box P3
FTO fat mass and obesity associated
FYN FYN proto-oncogene, Src family tyrosine kinase
G0S2 G0/G1 switch 2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GARS glycyl-tRNA synthetase
GATA3 GATA binding protein 3
GDE1 glycerophosphodiester phosphodiesterase 1
GDNF glial cell derived neurotrophic factor
GFRA1 GDNF family receptor alpha 1
GGNBP2 gametogenetin binding protein 2
GHR growth hormone receptor
GHRH growth hormone releasing hormone
GJA1 gap junction protein, alpha 1, 43kDa
GLB1 galactosidase, beta 1
GLI1 GLI family zinc finger 1
GLI2 GLI family zinc finger 2
GLS glutaminase
GPER1 G protein-coupled estrogen receptor 1
GRB2 growth factor receptor-bound protein 2
GRM1 glutamate receptor, metabotropic 1
GRN granulin
GRPR gastrin-releasing peptide receptor
GSN gelsolin
GSTK1 glutathione S-transferase kappa 1
GSTO1 glutathione S-transferase omega 1
GSTP1 glutathione S-transferase pi 1
HDAC2 histone deacetylase 2
HDAC5 histone deacetylase 5
HDAC6 histone deacetylase 6
HEATR6 HEAT repeat containing 6
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HOXB13 homeobox B13
HOXB3 homeobox B3
HOXB5 homeobox B5
HPSE heparanase
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB8 heat shock 22kDa protein 8
IDO1 indoleamine 2,3-dioxygenase 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNB1 interferon, beta 1, fibroblast
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2R insulin-like growth factor 2 receptor
IGFBP4 insulin-like growth factor binding protein 4
IGFBP5 insulin-like growth factor binding protein 5
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL10 interleukin 10
IL17RB interleukin 17 receptor B
IL6 interleukin 6
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IRS1 insulin receptor substrate 1
ISG20 interferon stimulated exonuclease gene 20kDa
JAG1 jagged 1
JMJD6 jumonji domain containing 6
KDM5B lysine (K)-specific demethylase 5B
KDR kinase insert domain receptor
KIF17 kinesin family member 17
KIF18A kinesin family member 18A
KIF23 kinesin family member 23
KLF5 Kruppel-like factor 5 (intestinal)
KMT2C lysine (K)-specific methyltransferase 2C
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT5 keratin 5, type II
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
LEP leptin
LGR6 leucine-rich repeat containing G protein-coupled receptor 6
LHCGR luteinizing hormone/choriogonadotropin receptor
LOX lysyl oxidase
LUM lumican
LYN LYN proto-oncogene, Src family tyrosine kinase
MAOA monoamine oxidase A
MAP2K1 mitogen-activated protein kinase kinase 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPT microtubule-associated protein tau
MARCKS myristoylated alanine-rich protein kinase C substrate
MASTL microtubule associated serine/threonine kinase-like
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MEN1 multiple endocrine neoplasia I
MGC57346-CRHR1 MGC57346-CRHR1 readthrough
MGP matrix Gla protein
MKI67 marker of proliferation Ki-67
MMP1 matrix metallopeptidase 1
MNAT1 MNAT CDK-activating kinase assembly factor 1
MRPS30 mitochondrial ribosomal protein S30
MSI2 musashi RNA-binding protein 2
MSN moesin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NCOA1 nuclear receptor coactivator 1
NCOA3 nuclear receptor coactivator 3
NCOR2 nuclear receptor corepressor 2
NF2 neurofibromin 2 (merlin)
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NNAT neuronatin
NOS2 nitric oxide synthase 2, inducible
NOTCH3 notch 3
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR5A2 nuclear receptor subfamily 5, group A, member 2
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
OCIAD1 OCIA domain containing 1
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
ORAI3 ORAI calcium release-activated calcium modulator 3
OSM oncostatin M
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PADI2 peptidyl arginine deiminase, type II
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PCBP4 poly(rC) binding protein 4
PCNA proliferating cell nuclear antigen
PCSK6 proprotein convertase subtilisin/kexin type 6
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PEA15 phosphoprotein enriched in astrocytes 15
PELP1 proline, glutamate and leucine rich protein 1
PER3 period circadian clock 3
PGR progesterone receptor
PHB prohibitin
PHB2 prohibitin 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIAS3 protein inhibitor of activated STAT, 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PITPNB phosphatidylinositol transfer protein, beta
PKM pyruvate kinase, muscle
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
PON1 paraoxonase 1
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPIF peptidylprolyl isomerase F
PRCP prolylcarboxypeptidase (angiotensinase C)
PRDX1 peroxiredoxin 1
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit
PRL prolactin
PRMT2 protein arginine methyltransferase 2
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTK2B protein tyrosine kinase 2 beta
PTK6 protein tyrosine kinase 6
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTTG1 pituitary tumor-transforming 1
PTTG1IP pituitary tumor-transforming 1 interacting protein
PXN paxillin
RAB27B RAB27B, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
RAD51 RAD51 recombinase
RAI2 retinoic acid induced 2
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RASAL2 RAS protein activator like 2
RBBP8 retinoblastoma binding protein 8
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBM38 RNA binding motif protein 38
RBP2 retinol binding protein 2, cellular
RET ret proto-oncogene
RGCC regulator of cell cycle
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPAIN RPA interacting protein
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RUNX1 runt-related transcription factor 1
RUNX3 runt-related transcription factor 3
S100A7 S100 calcium binding protein A7
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDCBP syndecan binding protein (syntenin)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEPT4 septin 4
SET SET nuclear proto-oncogene
SETD1A SET domain containing 1A
SFMBT2 Scm-like with four mbt domains 2
SFRP1 secreted frizzled-related protein 1
SGK3 serum/glucocorticoid regulated kinase family, member 3
SGSM2 small G protein signaling modulator 2
SHARPIN SHANK-associated RH domain interactor
SHBG sex hormone-binding globulin
SHOX2 short stature homeobox 2
SIAH2 siah E3 ubiquitin protein ligase 2
SIPA1 signal-induced proliferation-associated 1
SIRT1 sirtuin 1
SIRT4 sirtuin 4
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SLU7 SLU7 splicing factor homolog (S. cerevisiae)
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNAI2 snail family zinc finger 2
SOST sclerostin
SOX2 SRY (sex determining region Y)-box 2
SP1 Sp1 transcription factor
SPDEF SAM pointed domain containing ETS transcription factor
SPHK1 sphingosine kinase 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRSF6 serine/arginine-rich splicing factor 6
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STAR steroidogenic acute regulatory protein
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STC2 stanniocalcin 2
STING1 stimulator of interferon response cGAMP interactor 1
STS steroid sulfatase (microsomal), isozyme S
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TADA3 transcriptional adaptor 3
TARBP2 TAR (HIV-1) RNA binding protein 2
TAS2R38 taste receptor, type 2, member 38
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFAM transcription factor A, mitochondrial
TFF3 trefoil factor 3 (intestinal)
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TK1 thymidine kinase 1, soluble
TLR9 toll-like receptor 9
TMEM14A transmembrane protein 14A
TMPO thymopoietin
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TOP2A topoisomerase (DNA) II alpha 170kDa
TOX3 TOX high mobility group box family member 3
TP53 tumor protein p53
TRIM25 tripartite motif containing 25
TRIM28 tripartite motif containing 28
TRIM29 tripartite motif containing 29
TRIP10 thyroid hormone receptor interactor 10
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TWIST1 twist family bHLH transcription factor 1
TXNIP thioredoxin interacting protein
TXNRD1 thioredoxin reductase 1
UBASH3B ubiquitin associated and SH3 domain containing B
UBE2I ubiquitin-conjugating enzyme E2I
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
VEGFA vascular endothelial growth factor A
VRK1 vaccinia related kinase 1
WBP2 WW domain binding protein 2
WDR7 WD repeat domain 7
WISP2 WNT1 inducible signaling pathway protein 2
WNT1 wingless-type MMTV integration site family, member 1
WNT5A wingless-type MMTV integration site family, member 5A
WNT7A wingless-type MMTV integration site family, member 7A
WWC1 WW and C2 domain containing 1
WWP1 WW domain containing E3 ubiquitin protein ligase 1
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
YBX1 Y box binding protein 1
YPEL3 yippee-like 3 (Drosophila)
ZBTB12 zinc finger and BTB domain containing 12
ZEB1 zinc finger E-box binding homeobox 1
ZFHX3 zinc finger homeobox 3
ZNF217 zinc finger protein 217
ZNF365 zinc finger protein 365
ZNF366 zinc finger protein 366
ZNF423 zinc finger protein 423
ZNF645 zinc finger protein 645