| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Olanzapine perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Olanzapine_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.267579 |
| SMAD3 | SMAD family member 3 | 0.137259 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.110411 |
| MACC1 | metastasis associated in colon cancer 1 | 0.102503 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.100398 |
| SPATA13 | spermatogenesis associated 13 | 0.0903066 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.082535 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0767679 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0708988 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0618899 |
| CANX | calnexin | 0.0582202 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0549721 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0534934 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0529328 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0495878 |
| CTBP2 | C-terminal binding protein 2 | 0.0491759 |
| HKDC1 | hexokinase domain containing 1 | 0.0465404 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0459349 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0443876 |
| DST | dystonin | 0.0437069 |
| MYO1E | myosin IE | 0.0434954 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0428086 |
| VCL | vinculin | 0.0424359 |
| BCL2L1 | BCL2-like 1 | 0.0418873 |
| EZR | ezrin | 0.0418036 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0407721 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0396654 |
| ITGA6 | integrin, alpha 6 | 0.0391647 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0389382 |
| MYO10 | myosin X | 0.0387959 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.038488 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0376353 |
| KRT18 | keratin 18, type I | 0.0369676 |
| CCNL1 | cyclin L1 | 0.0366695 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0366048 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0359675 |
| TMC5 | transmembrane channel-like 5 | 0.0357528 |
| YAP1 | Yes-associated protein 1 | 0.0354463 |
| KYNU | kynureninase | 0.0343544 |
| AREG | amphiregulin | 0.0335099 |
| MYO5B | myosin VB | 0.0331092 |
| SLK | STE20-like kinase | 0.0330064 |
| DSPP | dentin sialophosphoprotein | 0.0329557 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0325415 |
| EREG | epiregulin | 0.0324853 |
| XDH | xanthine dehydrogenase | 0.0323536 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0321776 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0320467 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0319933 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0319372 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.031422 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0312889 |
| APP | amyloid beta (A4) precursor protein | 0.0308944 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0308699 |
| ADAR | adenosine deaminase, RNA-specific | 0.0303901 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0302308 |
| FNIP2 | folliculin interacting protein 2 | 0.0301991 |
| DUSP16 | dual specificity phosphatase 16 | 0.0299652 |
| ETV6 | ets variant 6 | 0.0299413 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0299075 |
| DIAPH1 | diaphanous-related formin 1 | 0.0299063 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0298515 |
| TJP2 | tight junction protein 2 | 0.0292489 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.029108 |
| COPA | coatomer protein complex, subunit alpha | 0.0290237 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0287857 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0284271 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0276632 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0274244 |
| USP54 | ubiquitin specific peptidase 54 | 0.0270364 |
| SEPTIN9 | septin 9 | 0.0269697 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0267728 |
| NEBL | nebulette | 0.0266363 |
| FAT1 | FAT atypical cadherin 1 | 0.0266236 |
| RBM47 | RNA binding motif protein 47 | 0.0261915 |
| FAM120A | family with sequence similarity 120A | 0.0258618 |
| TJP1 | tight junction protein 1 | 0.0257509 |
| SLMAP | sarcolemma associated protein | 0.0256905 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0256637 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0254355 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.024966 |
| ZNF292 | zinc finger protein 292 | 0.0249527 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.024903 |
| MLPH | melanophilin | 0.0247708 |
| STK24 | serine/threonine kinase 24 | 0.0244584 |
| EFNA5 | ephrin-A5 | 0.0240775 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0240378 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0239325 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0238175 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0236037 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.023223 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0231592 |
| IFNGR1 | interferon gamma receptor 1 | 0.0230466 |
| RND3 | Rho family GTPase 3 | 0.0229616 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0229454 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0227167 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0226996 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.022567 |
| DUSP10 | dual specificity phosphatase 10 | 0.022187 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0221457 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.138684 |
| INTS6 | integrator complex subunit 6 | -0.12679 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.115989 |
| HLA-B | major histocompatibility complex, class I, B | -0.108245 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.107021 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.101352 |
| XAF1 | XIAP associated factor 1 | -0.0946394 |
| NPSR1 | neuropeptide S receptor 1 | -0.0906734 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0886048 |
| PLSCR2 | phospholipid scramblase 2 | -0.0879719 |
| TXNIP | thioredoxin interacting protein | -0.0810449 |
| RPL35A | ribosomal protein L35a | -0.0765344 |
| LCN2 | lipocalin 2 | -0.0746564 |
| B2M | beta-2-microglobulin | -0.0707353 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0646833 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.064619 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0610233 |
| EGR1 | early growth response 1 | -0.0606013 |
| SQSTM1 | sequestosome 1 | -0.06019 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0587362 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0579047 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0560071 |
| ACTG1 | actin gamma 1 | -0.0555355 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0550271 |
| HLA-C | major histocompatibility complex, class I, C | -0.0548209 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0540134 |
| PRKCA | protein kinase C, alpha | -0.0540108 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0528717 |
| RPS6 | ribosomal protein S6 | -0.0518562 |
| RIGI | RNA sensor RIG-I | -0.0496568 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0488527 |
| MUC20 | mucin 20, cell surface associated | -0.0477875 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0473819 |
| SP100 | SP100 nuclear antigen | -0.046781 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0466307 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.045845 |
| MUC13 | mucin 13, cell surface associated | -0.044003 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0437181 |
| AHNAK | AHNAK nucleoprotein | -0.0433879 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0433456 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0428457 |
| RPL34 | ribosomal protein L34 | -0.0424032 |
| FHIT | fragile histidine triad | -0.0423177 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0417567 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0408343 |
| RPLP1 | ribosomal protein, large, P1 | -0.0403434 |
| HMGB1 | high mobility group box 1 | -0.0401908 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0400978 |
| PTMA | prothymosin, alpha | -0.0400904 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0397312 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | -0.0393472 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0384522 |
| AHI1 | Abelson helper integration site 1 | -0.0381649 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0377257 |
| NDRG1 | N-myc downstream regulated 1 | -0.037329 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.037221 |
| VMP1 | vacuole membrane protein 1 | -0.03696 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0368073 |
| RBM39 | RNA binding motif protein 39 | -0.0364142 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0354226 |
| TMSB10 | thymosin beta 10 | -0.0341895 |
| NF1 | neurofibromin 1 | -0.0341083 |
| MT2A | metallothionein 2A | -0.0340504 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.03344 |
| H3-3B | H3.3 histone B | -0.0334182 |
| SSH2 | slingshot protein phosphatase 2 | -0.0332624 |
| RPL12 | ribosomal protein L12 | -0.0331559 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0329364 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0326704 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0324202 |
| RRBP1 | ribosome binding protein 1 | -0.0324156 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0319177 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.031652 |
| RNF43 | ring finger protein 43 | -0.0315399 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0313679 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0312454 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0311904 |
| FUS | FUS RNA binding protein | -0.031137 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.0308498 |
| FBXO39 | F-box protein 39 | -0.0294078 |
| H1-0 | H1.0 linker histone | -0.0292846 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0292108 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0290543 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0286927 |
| GPX2 | glutathione peroxidase 2 | -0.0286517 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0284661 |
| EPCAM | epithelial cell adhesion molecule | -0.0284567 |
| ANXA4 | annexin A4 | -0.0283668 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.028019 |
| RAD51B | RAD51 paralog B | -0.0278598 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0277005 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0270657 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0269725 |
| S100A10 | S100 calcium binding protein A10 | -0.0269667 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0268419 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0267959 |
| MEIS2 | Meis homeobox 2 | -0.0267588 |
| PHF3 | PHD finger protein 3 | -0.0263348 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0259292 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0258229 |
