| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Olanzapine perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Olanzapine_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.145601 |
| CDH13 | cadherin 13 | 0.130069 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0590922 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0549905 |
| COL5A1 | collagen, type V, alpha 1 | 0.0465506 |
| VEGFA | vascular endothelial growth factor A | 0.0382545 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0366469 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0362651 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0343129 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0329919 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0304712 |
| GLIS3 | GLIS family zinc finger 3 | 0.0270914 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0268551 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0261747 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0259845 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0259708 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0252854 |
| HDAC9 | histone deacetylase 9 | 0.0249243 |
| PDLIM5 | PDZ and LIM domain 5 | 0.024373 |
| EFNA5 | ephrin-A5 | 0.0242476 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0242394 |
| VCL | vinculin | 0.0238053 |
| EGFR | epidermal growth factor receptor | 0.0237535 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0226138 |
| ATXN1 | ataxin 1 | 0.0225246 |
| RND3 | Rho family GTPase 3 | 0.0217671 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.021641 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0209178 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0206157 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.020572 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0205603 |
| PLEC | plectin | 0.0204897 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0203694 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0192815 |
| ATF4 | activating transcription factor 4 | 0.0188461 |
| SDC2 | syndecan 2 | 0.0184326 |
| NAV2 | neuron navigator 2 | 0.0183873 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0182667 |
| NAV1 | neuron navigator 1 | 0.018254 |
| FBN1 | fibrillin 1 | 0.0179874 |
| NEK10 | NIMA-related kinase 10 | 0.017982 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0179134 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0178698 |
| CNTN5 | contactin 5 | 0.0171766 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0171437 |
| MYO10 | myosin X | 0.0171119 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0168751 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0166427 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0165101 |
| CALD1 | caldesmon 1 | 0.0163403 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0161789 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0160923 |
| STC2 | stanniocalcin 2 | 0.0159146 |
| GOLGB1 | golgin B1 | 0.0154999 |
| FOXP1 | forkhead box P1 | 0.0151507 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0150642 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0148615 |
| EXOC4 | exocyst complex component 4 | 0.0148242 |
| HMGA2 | high mobility group AT-hook 2 | 0.0144864 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.0141942 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0140363 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0139383 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0138797 |
| FLNA | filamin A, alpha | 0.0137732 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0137345 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0136216 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0134283 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0131615 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0131172 |
| SETBP1 | SET binding protein 1 | 0.013025 |
| FNIP1 | folliculin interacting protein 1 | 0.0130076 |
| INTS6 | integrator complex subunit 6 | 0.0128908 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0127504 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0127035 |
| GRB10 | growth factor receptor-bound protein 10 | 0.012618 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0125619 |
| CUX1 | cut-like homeobox 1 | 0.012415 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0123684 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0123049 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0122956 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0121479 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0121325 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0121283 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.012108 |
| RSU1 | Ras suppressor protein 1 | 0.0120999 |
| RBPMS | RNA binding protein with multiple splicing | 0.0120563 |
| EPHB1 | EPH receptor B1 | 0.0118815 |
| DGKI | diacylglycerol kinase, iota | 0.0118692 |
| DST | dystonin | 0.0114486 |
| ZNF644 | zinc finger protein 644 | 0.0114462 |
| RUNX1 | runt-related transcription factor 1 | 0.0113964 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0112003 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0110939 |
| PRKCA | protein kinase C, alpha | 0.0110521 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0109118 |
| CLMP | CXADR-like membrane protein | 0.0108303 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0108094 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0107629 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0107012 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0103703 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.266892 |
| COL1A1 | collagen, type I, alpha 1 | -0.186078 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.133485 |
| CD44 | CD44 molecule (Indian blood group) | -0.119937 |
| ENO1 | enolase 1, (alpha) | -0.109819 |
| MT2A | metallothionein 2A | -0.107494 |
| UBC | ubiquitin C | -0.101131 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0922885 |
| VIM | vimentin | -0.0774592 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0745313 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0637284 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0600654 |
| PTMA | prothymosin, alpha | -0.0568098 |
| COL1A2 | collagen, type I, alpha 2 | -0.0560101 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0553384 |
| LDHA | lactate dehydrogenase A | -0.0551611 |
| CALR | calreticulin | -0.0503799 |
| TMSB10 | thymosin beta 10 | -0.0497368 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0481609 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0458887 |
| STC1 | stanniocalcin 1 | -0.045764 |
| PKM | pyruvate kinase, muscle | -0.0444808 |
| CALU | calumenin | -0.0444219 |
| ATP13A3 | ATPase type 13A3 | -0.0421236 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0361207 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0352593 |
| B2M | beta-2-microglobulin | -0.0348708 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0345451 |
| RPS27A | ribosomal protein S27a | -0.0343831 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0339552 |
| ARRDC3 | arrestin domain containing 3 | -0.0336376 |
| SMAD3 | SMAD family member 3 | -0.0331311 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0315552 |
| AHNAK | AHNAK nucleoprotein | -0.0312146 |
| MT1X | metallothionein 1X | -0.0307714 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0291772 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0286161 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0285002 |
| SPAG9 | sperm associated antigen 9 | -0.0283292 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0282395 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0278137 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0271269 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0268213 |
| RPS8 | ribosomal protein S8 | -0.0264605 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.026147 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0260231 |
| ZNF292 | zinc finger protein 292 | -0.0250935 |
| HLA-B | major histocompatibility complex, class I, B | -0.0250515 |
| CLIC4 | chloride intracellular channel 4 | -0.0249472 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0240477 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0237811 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0233516 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0230983 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0229556 |
| PTK2 | protein tyrosine kinase 2 | -0.022809 |
| IL6 | interleukin 6 | -0.0222579 |
| ANXA2 | annexin A2 | -0.0218876 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0217864 |
| TPM4 | tropomyosin 4 | -0.0214463 |
| GOLGA4 | golgin A4 | -0.0213235 |
| POSTN | periostin, osteoblast specific factor | -0.0212673 |
| S100A6 | S100 calcium binding protein A6 | -0.0212159 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0210876 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.020912 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0204634 |
| MAP1B | microtubule-associated protein 1B | -0.0204047 |
| POTEF | POTE ankyrin domain family, member F | -0.0202551 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0198979 |
| MX2 | MX dynamin-like GTPase 2 | -0.0198267 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.019419 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0193953 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0193056 |
| ACTG1 | actin gamma 1 | -0.0193011 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0192342 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0191695 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0191399 |
| PCBP2 | poly(rC) binding protein 2 | -0.0191355 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0191141 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0190812 |
| IER3 | immediate early response 3 | -0.019042 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0189701 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0189408 |
| YBX1 | Y box binding protein 1 | -0.0185994 |
| RPL8 | ribosomal protein L8 | -0.0185935 |
| JUN | jun proto-oncogene | -0.0184902 |
| INHBA | inhibin, beta A | -0.0182992 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0182774 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0179448 |
| LOX | lysyl oxidase | -0.0178927 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0177192 |
| SRGN | serglycin | -0.017693 |
| TAGLN2 | transgelin 2 | -0.0175729 |
| AXL | AXL receptor tyrosine kinase | -0.0170092 |
| RACK1 | receptor for activated C kinase 1 | -0.0169939 |
| VCAN | versican | -0.0169685 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0169339 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0169215 |
| RLF | rearranged L-myc fusion | -0.01679 |
| RPL23 | ribosomal protein L23 | -0.0165126 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0164854 |
