| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Olanzapine perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Olanzapine_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.170735 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0780591 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0753831 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0749156 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0729806 |
| VEGFA | vascular endothelial growth factor A | 0.0669102 |
| TF | transferrin | 0.0622472 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0605094 |
| FAM107B | family with sequence similarity 107, member B | 0.0548083 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0525327 |
| DSPP | dentin sialophosphoprotein | 0.0524663 |
| PLIN2 | perilipin 2 | 0.0501824 |
| INTS6 | integrator complex subunit 6 | 0.0496954 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0463323 |
| ATXN1 | ataxin 1 | 0.0454228 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0447706 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0402071 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.038762 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0383322 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0375324 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.035963 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0345997 |
| FLNA | filamin A, alpha | 0.0340061 |
| KYNU | kynureninase | 0.0337972 |
| TNS1 | tensin 1 | 0.0323415 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0321643 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.030631 |
| PLEC | plectin | 0.0296146 |
| RPS12 | ribosomal protein S12 | 0.0285404 |
| KRT18 | keratin 18, type I | 0.0281136 |
| SVIL | supervillin | 0.0280814 |
| DIAPH1 | diaphanous-related formin 1 | 0.0274297 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0272371 |
| MYO1E | myosin IE | 0.027015 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0267728 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0264684 |
| DTNA | dystrobrevin, alpha | 0.0263376 |
| TLE4 | transducin-like enhancer of split 4 | 0.0262617 |
| HMGA1 | high mobility group AT-hook 1 | 0.0261636 |
| PALLD | palladin, cytoskeletal associated protein | 0.0260426 |
| STC2 | stanniocalcin 2 | 0.0259718 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0246225 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0241598 |
| RBM19 | RNA binding motif protein 19 | 0.0240696 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.023866 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0237406 |
| SEPTIN9 | septin 9 | 0.0237097 |
| ASPH | aspartate beta-hydroxylase | 0.0233986 |
| FERMT2 | fermitin family member 2 | 0.0228528 |
| DUSP16 | dual specificity phosphatase 16 | 0.0227365 |
| FAT1 | FAT atypical cadherin 1 | 0.0217478 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0211996 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0211867 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0201413 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.020122 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0198153 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0197703 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0197236 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.0197156 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0197154 |
| CANX | calnexin | 0.01906 |
| CLIC4 | chloride intracellular channel 4 | 0.0190487 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0189846 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.018716 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0186851 |
| HSPA8 | heat shock 70kDa protein 8 | 0.018603 |
| RPL3 | ribosomal protein L3 | 0.0185933 |
| KRT19 | keratin 19, type I | 0.0183585 |
| STK17A | serine/threonine kinase 17a | 0.0182085 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0180995 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0180504 |
| USP47 | ubiquitin specific peptidase 47 | 0.0174667 |
| EFNA1 | ephrin-A1 | 0.0174059 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.017132 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0170462 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0169823 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0169264 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0168758 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.016799 |
| AHSG | alpha-2-HS-glycoprotein | 0.0167794 |
| TOP1 | topoisomerase (DNA) I | 0.0167195 |
| LMO7 | LIM domain 7 | 0.0166492 |
| EGFR | epidermal growth factor receptor | 0.0166223 |
| KIF21A | kinesin family member 21A | 0.0165602 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0163987 |
| MCL1 | myeloid cell leukemia 1 | 0.016352 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0163481 |
| NDRG1 | N-myc downstream regulated 1 | 0.0163478 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0163072 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0163046 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0160448 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.015729 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0156294 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 0.0155739 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0155639 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.015335 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0153331 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0153135 |
| RPS7 | ribosomal protein S7 | 0.0152463 |
| CCNYL1 | cyclin Y-like 1 | 0.0150664 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.385642 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.182164 |
| APOB | apolipoprotein B | -0.170548 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.16946 |
| GPC3 | glypican 3 | -0.137791 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.114456 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.103238 |
| MT2A | metallothionein 2A | -0.102036 |
| GPC6 | glypican 6 | -0.100666 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0941142 |
| EHBP1 | EH domain binding protein 1 | -0.0910898 |
| APOA2 | apolipoprotein A-II | -0.0877037 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.083775 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0780053 |
| SLC38A2 | solute carrier family 38, member 2 | -0.077074 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0743849 |
| RBM39 | RNA binding motif protein 39 | -0.0689888 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0635115 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0623448 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0611106 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0597095 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0591731 |
| JMJD1C | jumonji domain containing 1C | -0.0568549 |
| TMEM123 | transmembrane protein 123 | -0.0536141 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.053428 |
| DST | dystonin | -0.0504677 |
| TRIM26 | tripartite motif containing 26 | -0.050053 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0500469 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0496799 |
| OSMR | oncostatin M receptor | -0.0485373 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0482177 |
| ITGA1 | integrin, alpha 1 | -0.0481582 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0470912 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0459396 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0455114 |
| RPLP1 | ribosomal protein, large, P1 | -0.0450426 |
| FRMD5 | FERM domain containing 5 | -0.0448238 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0444096 |
| RPS21 | ribosomal protein S21 | -0.0441553 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0437898 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0433352 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0423036 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0422711 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0422067 |
| EGR1 | early growth response 1 | -0.0418214 |
| FN1 | fibronectin 1 | -0.0417213 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0416602 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0416123 |
| FTL | ferritin, light polypeptide | -0.041046 |
| RUNX1 | runt-related transcription factor 1 | -0.0409036 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0406794 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0389498 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0385621 |
| RPL35A | ribosomal protein L35a | -0.0376282 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0372049 |
| RRBP1 | ribosome binding protein 1 | -0.0362682 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0357576 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0356288 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0351574 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.03499 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0347263 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0343512 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0341409 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0338335 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0336747 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.03288 |
| TPM4 | tropomyosin 4 | -0.0325142 |
| GNAS | GNAS complex locus | -0.0322263 |
| SDC4 | syndecan 4 | -0.031434 |
| RPL34 | ribosomal protein L34 | -0.0312272 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.0300775 |
| CP | ceruloplasmin (ferroxidase) | -0.0299563 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.0296607 |
| NFIA | nuclear factor I/A | -0.0295908 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | -0.0294609 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0294134 |
| ENO1 | enolase 1, (alpha) | -0.029346 |
| FERMT1 | fermitin family member 1 | -0.0291402 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0289617 |
| RPL11 | ribosomal protein L11 | -0.0288175 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0282807 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0281266 |
| IER3 | immediate early response 3 | -0.0279902 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0277737 |
| CTSB | cathepsin B | -0.0276913 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0276493 |
| H1-0 | H1.0 linker histone | -0.0273905 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0272328 |
| RPL32 | ribosomal protein L32 | -0.0269644 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0266075 |
| RIGI | RNA sensor RIG-I | -0.0263074 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0262462 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0259298 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0259285 |
| PHF21A | PHD finger protein 21A | -0.0258829 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0257436 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0257365 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0257293 |
| RPS13 | ribosomal protein S13 | -0.0253534 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | -0.0251633 |
