| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Olanzapine perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Olanzapine_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.0900087 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0716199 |
| PLEC | plectin | 0.0703276 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0664793 |
| LMO7 | LIM domain 7 | 0.0604119 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0563809 |
| INTS6 | integrator complex subunit 6 | 0.0551171 |
| SMAD3 | SMAD family member 3 | 0.0545948 |
| VCL | vinculin | 0.0475093 |
| FLNA | filamin A, alpha | 0.0467279 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0451397 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0451155 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0431525 |
| LAMC2 | laminin, gamma 2 | 0.038579 |
| RASAL2 | RAS protein activator like 2 | 0.0375012 |
| AMOTL1 | angiomotin like 1 | 0.0372317 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0355516 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0333479 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0326408 |
| SEPTIN9 | septin 9 | 0.0310538 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.028764 |
| PRELID2 | PRELI domain containing 2 | 0.0285417 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0281432 |
| BLCAP | bladder cancer associated protein | 0.0276822 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0273925 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.027167 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0263344 |
| EFNB2 | ephrin-B2 | 0.026267 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0261183 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0260015 |
| CAPRIN2 | caprin family member 2 | 0.0258257 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0256274 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0251566 |
| CTBP2 | C-terminal binding protein 2 | 0.0249111 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0246856 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | 0.0241594 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0240125 |
| CLIC4 | chloride intracellular channel 4 | 0.0238999 |
| MSN | moesin | 0.0232176 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0229447 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0226488 |
| FN1 | fibronectin 1 | 0.022523 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0224875 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0222433 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0220031 |
| MCL1 | myeloid cell leukemia 1 | 0.0213015 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0211259 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0209396 |
| PLXNA2 | plexin A2 | 0.020855 |
| ACTN1 | actinin, alpha 1 | 0.020494 |
| CEP250 | centrosomal protein 250kDa | 0.0202712 |
| DST | dystonin | 0.0202374 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0200432 |
| EFNA5 | ephrin-A5 | 0.0199869 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0198759 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.019802 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0195403 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0195198 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0195157 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0193397 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0192541 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0191399 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0186872 |
| ASPH | aspartate beta-hydroxylase | 0.0183104 |
| DIAPH1 | diaphanous-related formin 1 | 0.0179537 |
| RCOR1 | REST corepressor 1 | 0.0178875 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0177901 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0177016 |
| ACTN4 | actinin, alpha 4 | 0.0174554 |
| EGFR | epidermal growth factor receptor | 0.0171641 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0167782 |
| BCL2L1 | BCL2-like 1 | 0.0164978 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0163764 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0163154 |
| ANO6 | anoctamin 6 | 0.0162819 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0159467 |
| GPR176 | G protein-coupled receptor 176 | 0.0158667 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0157015 |
| TJP1 | tight junction protein 1 | 0.0156797 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0156103 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0154999 |
| ZNF75D | zinc finger protein 75D | 0.0152544 |
| KRT6A | keratin 6A, type II | 0.0150209 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.015004 |
| EHBP1 | EH domain binding protein 1 | 0.0149948 |
| PODXL | podocalyxin-like | 0.0149761 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0149158 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0148806 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0146154 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0146007 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0144765 |
| SLC35H1 | solute carrier family 35 member H1 | 0.0142634 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 | 0.0141524 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0141354 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0140981 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.014098 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.0140351 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0139907 |
| MTAP | methylthioadenosine phosphorylase | 0.0139016 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0138264 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.233628 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.212116 |
| RPS6 | ribosomal protein S6 | -0.124485 |
| RPS21 | ribosomal protein S21 | -0.107168 |
| NDRG1 | N-myc downstream regulated 1 | -0.10016 |
| RPS8 | ribosomal protein S8 | -0.0932666 |
| PTMA | prothymosin, alpha | -0.0905502 |
| POTEF | POTE ankyrin domain family, member F | -0.0902076 |
| B2M | beta-2-microglobulin | -0.0842884 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0824013 |
| S100A10 | S100 calcium binding protein A10 | -0.0793206 |
| MEF2A | myocyte enhancer factor 2A | -0.0740132 |
| RPS13 | ribosomal protein S13 | -0.0720879 |
| TMSB4X | thymosin beta 4, X-linked | -0.0684504 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0656496 |
| RPL35A | ribosomal protein L35a | -0.0651034 |
| RPLP1 | ribosomal protein, large, P1 | -0.0646923 |
| RPLP2 | ribosomal protein, large, P2 | -0.0631242 |
| TMSB10 | thymosin beta 10 | -0.0631206 |
| MT2A | metallothionein 2A | -0.0612198 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0610046 |
| SULF1 | sulfatase 1 | -0.0596857 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.058942 |
| CLU | clusterin | -0.0584087 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0582133 |
| GNAS | GNAS complex locus | -0.0575351 |
| S100A9 | S100 calcium binding protein A9 | -0.0571423 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0564751 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0560802 |
| RPS19 | ribosomal protein S19 | -0.053572 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0531842 |
| GOLGA4 | golgin A4 | -0.0529428 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0523529 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0519068 |
| RPL34 | ribosomal protein L34 | -0.0518638 |
| FTL | ferritin, light polypeptide | -0.0511798 |
| MTSS1 | metastasis suppressor 1 | -0.0504898 |
| RPL8 | ribosomal protein L8 | -0.0490942 |
| IGF2 | insulin-like growth factor 2 | -0.0481079 |
| ENO1 | enolase 1, (alpha) | -0.0473745 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0469826 |
| RPL37 | ribosomal protein L37 | -0.0469246 |
| RPS25 | ribosomal protein S25 | -0.0450055 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0449793 |
| S100A6 | S100 calcium binding protein A6 | -0.0444677 |
| CD44 | CD44 molecule (Indian blood group) | -0.0440026 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0429089 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0421643 |
| HLA-B | major histocompatibility complex, class I, B | -0.0419028 |
| S100A11 | S100 calcium binding protein A11 | -0.0414257 |
| DSTN | destrin (actin depolymerizing factor) | -0.0403032 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0401594 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0398637 |
| RPL11 | ribosomal protein L11 | -0.0398241 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0398169 |
| ITGA6 | integrin, alpha 6 | -0.0392791 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0385328 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0377562 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0374513 |
| PGK1 | phosphoglycerate kinase 1 | -0.0369862 |
| RPL5 | ribosomal protein L5 | -0.0367942 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0366647 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0365284 |
| RPL12 | ribosomal protein L12 | -0.036231 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0361865 |
| RPL23 | ribosomal protein L23 | -0.036051 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0360237 |
| RPS23 | ribosomal protein S23 | -0.0356496 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0353317 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0351564 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0349141 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0348366 |
| RPS14 | ribosomal protein S14 | -0.0345934 |
| RPL30 | ribosomal protein L30 | -0.034336 |
| RPS29 | ribosomal protein S29 | -0.0342791 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0341162 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0339473 |
| RPL36 | ribosomal protein L36 | -0.0329385 |
| CD99 | CD99 molecule | -0.0326311 |
| S100A2 | S100 calcium binding protein A2 | -0.0326309 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0323618 |
| PFN1 | profilin 1 | -0.032355 |
| RPL31 | ribosomal protein L31 | -0.0323277 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0321673 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0315445 |
| RPL27A | ribosomal protein L27a | -0.03134 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0313334 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0312743 |
| RPS27 | ribosomal protein S27 | -0.030496 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.030494 |
| RPS3 | ribosomal protein S3 | -0.0304851 |
| RPLP0 | ribosomal protein, large, P0 | -0.0304312 |
| CSTB | cystatin B (stefin B) | -0.0303558 |
| RPL35 | ribosomal protein L35 | -0.030322 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0302072 |
| TPM4 | tropomyosin 4 | -0.029964 |
| RPL28 | ribosomal protein L28 | -0.0293891 |
| RPL37A | ribosomal protein L37a | -0.0292187 |
| RPS24 | ribosomal protein S24 | -0.0291601 |
| FOSL1 | FOS-like antigen 1 | -0.0290701 |
