| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Olanzapine perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Olanzapine_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.223494 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.117478 |
| MYOF | myoferlin | 0.101586 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0800331 |
| SEPTIN9 | septin 9 | 0.0736702 |
| TJP1 | tight junction protein 1 | 0.0725229 |
| EZR | ezrin | 0.0665451 |
| EMP1 | epithelial membrane protein 1 | 0.0662016 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0632773 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0631476 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0623107 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0618258 |
| SMAD3 | SMAD family member 3 | 0.060979 |
| CAPN8 | calpain 8 | 0.0608187 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0607707 |
| ACTN4 | actinin, alpha 4 | 0.0592894 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0587916 |
| ASPH | aspartate beta-hydroxylase | 0.0553419 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0549698 |
| ANXA2 | annexin A2 | 0.0544595 |
| GDA | guanine deaminase | 0.051465 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0506448 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0506201 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0494204 |
| PLEC | plectin | 0.0479681 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0474235 |
| BCL2L1 | BCL2-like 1 | 0.0472047 |
| LAMA4 | laminin, alpha 4 | 0.0463688 |
| CTBP2 | C-terminal binding protein 2 | 0.0460893 |
| MYO1E | myosin IE | 0.0457307 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0456338 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0446021 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0436031 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0430719 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0424714 |
| RNF213 | ring finger protein 213 | 0.040865 |
| FLNA | filamin A, alpha | 0.0408247 |
| ANXA11 | annexin A11 | 0.0401826 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0401362 |
| ATXN1 | ataxin 1 | 0.040031 |
| AHR | aryl hydrocarbon receptor | 0.0387735 |
| INTS6 | integrator complex subunit 6 | 0.0385837 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0380264 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0372042 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0370206 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.036504 |
| FAT1 | FAT atypical cadherin 1 | 0.0361403 |
| ECT2 | epithelial cell transforming 2 | 0.0358219 |
| POF1B | premature ovarian failure, 1B | 0.0355117 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0352383 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0350852 |
| FLNB | filamin B, beta | 0.0349732 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0341382 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0338362 |
| MCU | mitochondrial calcium uniporter | 0.0336034 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0334962 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0333321 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 0.0333014 |
| EFNB2 | ephrin-B2 | 0.0328877 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0326179 |
| DSPP | dentin sialophosphoprotein | 0.0325349 |
| RBM47 | RNA binding motif protein 47 | 0.0324998 |
| SNX9 | sorting nexin 9 | 0.0324219 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0318526 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.031695 |
| FBXO11 | F-box protein 11 | 0.0312618 |
| RCOR1 | REST corepressor 1 | 0.0311206 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0308899 |
| SGMS2 | sphingomyelin synthase 2 | 0.0307828 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0301367 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0299534 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0296008 |
| LIPH | lipase, member H | 0.0294217 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0289464 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0289301 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.028745 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0283512 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0283004 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0282173 |
| KRT18 | keratin 18, type I | 0.0281236 |
| MYO5B | myosin VB | 0.0277074 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0276292 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0275741 |
| DST | dystonin | 0.0275129 |
| TGFA | transforming growth factor, alpha | 0.0274651 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0274482 |
| MED13 | mediator complex subunit 13 | 0.0273379 |
| MCL1 | myeloid cell leukemia 1 | 0.0271617 |
| RASEF | RAS and EF-hand domain containing | 0.027101 |
| CMIP | c-Maf inducing protein | 0.0268589 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0264882 |
| WWOX | WW domain containing oxidoreductase | 0.0259207 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0255496 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0250824 |
| VCL | vinculin | 0.0249957 |
| EFNA5 | ephrin-A5 | 0.0249941 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0248977 |
| STK24 | serine/threonine kinase 24 | 0.0248144 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0247286 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0244929 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.123863 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.121839 |
| PTMA | prothymosin, alpha | -0.116833 |
| RPS6 | ribosomal protein S6 | -0.114719 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.101668 |
| RPL35A | ribosomal protein L35a | -0.0922505 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0851002 |
| TMSB10 | thymosin beta 10 | -0.0842252 |
| FTL | ferritin, light polypeptide | -0.0780335 |
| POTEF | POTE ankyrin domain family, member F | -0.0627855 |
| AGR2 | anterior gradient 2 | -0.061826 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0597763 |
| RPS25 | ribosomal protein S25 | -0.0589258 |
| WDR45B | WD repeat domain 45B | -0.057706 |
| GOLGA4 | golgin A4 | -0.0576383 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0559093 |
| S100A6 | S100 calcium binding protein A6 | -0.0524736 |
| RPLP1 | ribosomal protein, large, P1 | -0.0523521 |
| RPS8 | ribosomal protein S8 | -0.0510054 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0498426 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0495223 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.045723 |
| B2M | beta-2-microglobulin | -0.0430947 |
| NDRG1 | N-myc downstream regulated 1 | -0.0423031 |
| RPS3 | ribosomal protein S3 | -0.0414712 |
| RPL23 | ribosomal protein L23 | -0.0406356 |
| RPL19 | ribosomal protein L19 | -0.0406165 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0405862 |
| RPS19 | ribosomal protein S19 | -0.0400843 |
| RPL34 | ribosomal protein L34 | -0.0383638 |
| PGK1 | phosphoglycerate kinase 1 | -0.0379053 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0373648 |
| HLA-A | major histocompatibility complex, class I, A | -0.0372862 |
| ZNF292 | zinc finger protein 292 | -0.0366981 |
| TMEM123 | transmembrane protein 123 | -0.0352416 |
| S100A9 | S100 calcium binding protein A9 | -0.0347438 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0346258 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0342288 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0339384 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0337319 |
| VEGFA | vascular endothelial growth factor A | -0.0335205 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0330918 |
| RPS12 | ribosomal protein S12 | -0.0328531 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0319757 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0317217 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0315553 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0312954 |
| RPL26 | ribosomal protein L26 | -0.031284 |
| ATF5 | activating transcription factor 5 | -0.0312432 |
| RPL12 | ribosomal protein L12 | -0.0310158 |
| RPS16 | ribosomal protein S16 | -0.0307098 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0305601 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0297481 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0296883 |
| RPL36A | ribosomal protein L36a | -0.0295581 |
| RPL37A | ribosomal protein L37a | -0.0294145 |
| RPS29 | ribosomal protein S29 | -0.0292791 |
| PKM | pyruvate kinase, muscle | -0.028941 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0287763 |
| ENO1 | enolase 1, (alpha) | -0.0286782 |
| RPS21 | ribosomal protein S21 | -0.0286737 |
| HM13 | histocompatibility (minor) 13 | -0.0279071 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0276016 |
| DSTN | destrin (actin depolymerizing factor) | -0.0274737 |
| ITGB4 | integrin, beta 4 | -0.0273201 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0271378 |
| RPL9 | ribosomal protein L9 | -0.0270074 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0269433 |
| RPS27A | ribosomal protein S27a | -0.0268014 |
| RPS13 | ribosomal protein S13 | -0.0267156 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0265482 |
| RPL11 | ribosomal protein L11 | -0.026494 |
| THOC2 | THO complex 2 | -0.0264365 |
| FAM13A | family with sequence similarity 13, member A | -0.0263714 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0262512 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0262299 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.026127 |
| RPL8 | ribosomal protein L8 | -0.026111 |
| RPS17 | ribosomal protein S17 | -0.025092 |
| CDK6 | cyclin-dependent kinase 6 | -0.0248 |
| COG5 | component of oligomeric golgi complex 5 | -0.0247629 |
| RPS24 | ribosomal protein S24 | -0.0242238 |
| CBX3 | chromobox homolog 3 | -0.0241539 |
| DEK | DEK proto-oncogene | -0.0240594 |
| RPL31 | ribosomal protein L31 | -0.0240573 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0240116 |
| RPS11 | ribosomal protein S11 | -0.0237568 |
| RPS27 | ribosomal protein S27 | -0.0236267 |
| EPCAM | epithelial cell adhesion molecule | -0.0236261 |
| RPS20 | ribosomal protein S20 | -0.0235452 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0234726 |
| RPL5 | ribosomal protein L5 | -0.0233858 |
| RPLP0 | ribosomal protein, large, P0 | -0.0232843 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0232689 |
| S100P | S100 calcium binding protein P | -0.0231081 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0230427 |
| HLA-B | major histocompatibility complex, class I, B | -0.023016 |
| SETD5 | SET domain containing 5 | -0.0228866 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0227387 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.0227253 |
