| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Olanzapine perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Olanzapine_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.0839021 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0731449 |
| CAPRIN2 | caprin family member 2 | 0.0663931 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0484363 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0478557 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0468907 |
| RUNX1 | runt-related transcription factor 1 | 0.0465826 |
| TP63 | tumor protein p63 | 0.045494 |
| PRELID2 | PRELI domain containing 2 | 0.0450914 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0423721 |
| FMNL2 | formin-like 2 | 0.0415151 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.040528 |
| RAD51B | RAD51 paralog B | 0.0392679 |
| RPS12 | ribosomal protein S12 | 0.0390972 |
| VCL | vinculin | 0.0386754 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0383446 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0383252 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0381235 |
| INTS6 | integrator complex subunit 6 | 0.0374882 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0374107 |
| TGM2 | transglutaminase 2 | 0.0344793 |
| CMIP | c-Maf inducing protein | 0.0322923 |
| PLEC | plectin | 0.0306363 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0295463 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0286988 |
| RPS17 | ribosomal protein S17 | 0.0285674 |
| RPL35A | ribosomal protein L35a | 0.0278765 |
| CADM2 | cell adhesion molecule 2 | 0.0274243 |
| RCOR1 | REST corepressor 1 | 0.026746 |
| NEK10 | NIMA-related kinase 10 | 0.0262867 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0262485 |
| HOMER1 | homer scaffolding protein 1 | 0.0258259 |
| KRT18 | keratin 18, type I | 0.0253039 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0250917 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0248621 |
| RNF213 | ring finger protein 213 | 0.0247378 |
| RPL31 | ribosomal protein L31 | 0.024722 |
| RPS19 | ribosomal protein S19 | 0.0246147 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0244176 |
| HLA-A | major histocompatibility complex, class I, A | 0.0236226 |
| HLA-B | major histocompatibility complex, class I, B | 0.0231981 |
| PDE10A | phosphodiesterase 10A | 0.0227763 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0227411 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0224909 |
| SP100 | SP100 nuclear antigen | 0.0222876 |
| RTTN | rotatin | 0.0219593 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.021479 |
| AEBP2 | AE binding protein 2 | 0.0208651 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0206386 |
| RPS10 | ribosomal protein S10 | 0.0205311 |
| ECE1 | endothelin converting enzyme 1 | 0.0203587 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0202327 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0201729 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0200951 |
| WDR27 | WD repeat domain 27 | 0.0200949 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0200295 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0197849 |
| DPYD | dihydropyrimidine dehydrogenase | 0.019784 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0196531 |
| SVIL | supervillin | 0.0196443 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0196431 |
| DNER | delta/notch-like EGF repeat containing | 0.01953 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0192702 |
| FTL | ferritin, light polypeptide | 0.0192397 |
| DPH6 | diphthamine biosynthesis 6 | 0.0191864 |
| PRKCE | protein kinase C, epsilon | 0.0188845 |
| RPL36 | ribosomal protein L36 | 0.0187569 |
| VEGFA | vascular endothelial growth factor A | 0.0187171 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0186621 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0185539 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0184658 |
| RPL37A | ribosomal protein L37a | 0.018441 |
| BEGAIN | brain-enriched guanylate kinase-associated | 0.0183533 |
| RPS23 | ribosomal protein S23 | 0.0182933 |
| CEP250 | centrosomal protein 250kDa | 0.0181199 |
| RPS27 | ribosomal protein S27 | 0.0180519 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0180423 |
| RPS29 | ribosomal protein S29 | 0.0175492 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0173488 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.017236 |
| HPCAL1 | hippocalcin-like 1 | 0.0170764 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0167256 |
| SYAP1 | synapse associated protein 1 | 0.0161905 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0160363 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0158388 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0158376 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0156558 |
| PCDH1 | protocadherin 1 | 0.0156224 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0156216 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0151909 |
| FHIT | fragile histidine triad | 0.0149446 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | 0.0149144 |
| SMAD3 | SMAD family member 3 | 0.0148896 |
| SEPTIN9 | septin 9 | 0.0148672 |
| RPS14 | ribosomal protein S14 | 0.0148314 |
| RPLP2 | ribosomal protein, large, P2 | 0.0148004 |
| MRPL13 | mitochondrial ribosomal protein L13 | 0.0147845 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0147534 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0143574 |
| INF2 | inverted formin, FH2 and WH2 domain containing | 0.0142537 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.307168 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.169329 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.155258 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.113428 |
| RAI1 | retinoic acid induced 1 | -0.0980165 |
| TXNRD1 | thioredoxin reductase 1 | -0.0919476 |
| UBC | ubiquitin C | -0.0817953 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0779708 |
| AHNAK | AHNAK nucleoprotein | -0.07569 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0728095 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0678996 |
| RTN4 | reticulon 4 | -0.0632659 |
| APP | amyloid beta (A4) precursor protein | -0.0617932 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.059825 |
| ACTG1 | actin gamma 1 | -0.0596259 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0581847 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0570965 |
| CANX | calnexin | -0.0570525 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0556956 |
| EZR | ezrin | -0.0555806 |
| TMSB4X | thymosin beta 4, X-linked | -0.0535001 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0534741 |
| POTEF | POTE ankyrin domain family, member F | -0.0522953 |
| JUN | jun proto-oncogene | -0.0514454 |
| ENO1 | enolase 1, (alpha) | -0.0507229 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0498166 |
| VIM | vimentin | -0.0493388 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.047743 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0464713 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.046164 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0449482 |
| ANXA1 | annexin A1 | -0.0447515 |
| MT1X | metallothionein 1X | -0.0435486 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0427505 |
| CD44 | CD44 molecule (Indian blood group) | -0.0423195 |
| RPS27A | ribosomal protein S27a | -0.0419661 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0416659 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0415417 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0412323 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0410745 |
| SRGN | serglycin | -0.0407071 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.039881 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0397377 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0396585 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.038913 |
| PGK1 | phosphoglycerate kinase 1 | -0.038783 |
| PTMA | prothymosin, alpha | -0.0386514 |
| EREG | epiregulin | -0.038126 |
| ZFR | zinc finger RNA binding protein | -0.0371434 |
| RLF | rearranged L-myc fusion | -0.0370825 |
| RBM25 | RNA binding motif protein 25 | -0.0368675 |
| SEPTIN7 | septin 7 | -0.03651 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0364388 |
| LDHA | lactate dehydrogenase A | -0.0363735 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0361529 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0352667 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0351763 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0349521 |
| ZNF292 | zinc finger protein 292 | -0.0349508 |
| FBXO11 | F-box protein 11 | -0.0347486 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0347268 |
| EMP1 | epithelial membrane protein 1 | -0.0346274 |
| TMEM123 | transmembrane protein 123 | -0.0345218 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0343393 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0342845 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0341496 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0340289 |
| RIGI | RNA sensor RIG-I | -0.033949 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0338346 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0332532 |
| CEP170 | centrosomal protein 170kDa | -0.0331989 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0330108 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0327263 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0327086 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0326824 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0324279 |
| TMEM41B | transmembrane protein 41B | -0.0323459 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0323423 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0321035 |
| S100A6 | S100 calcium binding protein A6 | -0.0317949 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0314548 |
| S100A10 | S100 calcium binding protein A10 | -0.0311126 |
| TMSB10 | thymosin beta 10 | -0.0309478 |
| ANXA2 | annexin A2 | -0.030661 |
| CALU | calumenin | -0.0305028 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0303854 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0299309 |
| YBX3 | Y box binding protein 3 | -0.0298016 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0294962 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0291888 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0286037 |
| USP34 | ubiquitin specific peptidase 34 | -0.0285535 |
| WDR26 | WD repeat domain 26 | -0.0284534 |
| WDR45B | WD repeat domain 45B | -0.0284457 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0284302 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0279206 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0278159 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0275527 |
| WDR43 | WD repeat domain 43 | -0.0272614 |
| RPL5 | ribosomal protein L5 | -0.0271193 |
