| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Olanzapine perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Olanzapine_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.158779 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0883578 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0865314 |
| MCL1 | myeloid cell leukemia 1 | 0.0828418 |
| KRT18 | keratin 18, type I | 0.0815595 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0750511 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0739463 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0726756 |
| PLEC | plectin | 0.0601549 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0589767 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0580918 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0556423 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0552029 |
| CES1 | carboxylesterase 1 | 0.0536947 |
| LAMA4 | laminin, alpha 4 | 0.0526368 |
| DSPP | dentin sialophosphoprotein | 0.0509011 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.049221 |
| TOP1 | topoisomerase (DNA) I | 0.0479962 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0479798 |
| MYOF | myoferlin | 0.0436055 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0434603 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.042608 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0423643 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0397593 |
| SMAD3 | SMAD family member 3 | 0.0393473 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.038234 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0367682 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0360102 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0358729 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0358552 |
| WWOX | WW domain containing oxidoreductase | 0.0357683 |
| MSN | moesin | 0.0352315 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0350052 |
| SLTM | SAFB-like, transcription modulator | 0.0348934 |
| MAGEA4 | melanoma antigen family A4 | 0.0344778 |
| FLNA | filamin A, alpha | 0.034147 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0341197 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0337213 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.033265 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0329272 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.032496 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0322244 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0316499 |
| TES | testin LIM domain protein | 0.0313687 |
| ATF4 | activating transcription factor 4 | 0.0312901 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0303508 |
| HYOU1 | hypoxia up-regulated 1 | 0.0294126 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0293631 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0293086 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0291155 |
| BMP6 | bone morphogenetic protein 6 | 0.0288829 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0287048 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0285621 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0285003 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0283973 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.028278 |
| MT2A | metallothionein 2A | 0.027813 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.027794 |
| PYGL | phosphorylase, glycogen, liver | 0.0273809 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0267579 |
| FAM13A | family with sequence similarity 13, member A | 0.0265654 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0264811 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0263352 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0258658 |
| SVIL | supervillin | 0.0258162 |
| SDC1 | syndecan 1 | 0.0257636 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0257407 |
| DST | dystonin | 0.0257324 |
| EZR | ezrin | 0.0256031 |
| HMGA2 | high mobility group AT-hook 2 | 0.0255919 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0253872 |
| RPL7 | ribosomal protein L7 | 0.0252665 |
| RPS4X | ribosomal protein S4, X-linked | 0.0250827 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0243557 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0238198 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0236441 |
| TPM3 | tropomyosin 3 | 0.0234055 |
| ATP11A | ATPase, class VI, type 11A | 0.023043 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0229961 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0228662 |
| RNF149 | ring finger protein 149 | 0.0226226 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0225105 |
| CANX | calnexin | 0.0224214 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0224099 |
| SIK3 | SIK family kinase 3 | 0.022346 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0221324 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0220385 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0219077 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0216627 |
| FLNB | filamin B, beta | 0.021494 |
| SEPTIN9 | septin 9 | 0.0213253 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0211766 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0210649 |
| ZNF281 | zinc finger protein 281 | 0.0209437 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0207637 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0207113 |
| IRS2 | insulin receptor substrate 2 | 0.0206978 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.020563 |
| DIAPH1 | diaphanous-related formin 1 | 0.0202906 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0202355 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.329652 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.264619 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.150042 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.126581 |
| UBC | ubiquitin C | -0.119841 |
| EGFR | epidermal growth factor receptor | -0.110838 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.102487 |
| ASPH | aspartate beta-hydroxylase | -0.0981821 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0778516 |
| NDRG1 | N-myc downstream regulated 1 | -0.0777525 |
| TMSB10 | thymosin beta 10 | -0.0736296 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0726284 |
| INTS6 | integrator complex subunit 6 | -0.0695534 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0649451 |
| EGR1 | early growth response 1 | -0.0613977 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0581961 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0564108 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0562115 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0557697 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0557499 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0549666 |
| LAMC2 | laminin, gamma 2 | -0.0540814 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0533799 |
| NABP1 | nucleic acid binding protein 1 | -0.0513143 |
| ACTG1 | actin gamma 1 | -0.0504111 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0502314 |
| EFNA5 | ephrin-A5 | -0.0497464 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0496995 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0496066 |
| RPS27A | ribosomal protein S27a | -0.0486599 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0478224 |
| AHNAK | AHNAK nucleoprotein | -0.0449011 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0431933 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0416186 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0416044 |
| TNS3 | tensin 3 | -0.0414582 |
| FBXO11 | F-box protein 11 | -0.0407613 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0390972 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0382827 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0380413 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0365208 |
| MGAT4C | MGAT4 family, member C | -0.035775 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0357698 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0353449 |
| MYO1D | myosin ID | -0.0346701 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0344808 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0336463 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0333899 |
| SP100 | SP100 nuclear antigen | -0.0329031 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0327041 |
| RPS24 | ribosomal protein S24 | -0.0323266 |
| OSMR | oncostatin M receptor | -0.0321949 |
| HLA-B | major histocompatibility complex, class I, B | -0.0320937 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0316828 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0315506 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0311663 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0303997 |
| SQSTM1 | sequestosome 1 | -0.0303354 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0300714 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0299894 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0299496 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0295452 |
| WDR45B | WD repeat domain 45B | -0.0294637 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0294101 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0293521 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0291492 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0288551 |
| GM2A | GM2 ganglioside activator | -0.0282692 |
| MYO1E | myosin IE | -0.027906 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0273736 |
| RPL34 | ribosomal protein L34 | -0.0272725 |
| USP53 | ubiquitin specific peptidase 53 | -0.0272187 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0271694 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0268389 |
| WASF2 | WAS protein family, member 2 | -0.0266134 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0263669 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0263591 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0261836 |
| CCNI | cyclin I | -0.0261727 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0261011 |
| CP | ceruloplasmin (ferroxidase) | -0.025844 |
| ANXA2 | annexin A2 | -0.0257592 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0257332 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0256368 |
| GPC6 | glypican 6 | -0.0253838 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0251864 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0251753 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0251608 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0250393 |
| B2M | beta-2-microglobulin | -0.0247825 |
| SDC4 | syndecan 4 | -0.0245726 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0242043 |
| GNAS | GNAS complex locus | -0.0240689 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0233883 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0231368 |
| H1-0 | H1.0 linker histone | -0.0230916 |
| S100A10 | S100 calcium binding protein A10 | -0.0229776 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0228475 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0226254 |
| RPL30 | ribosomal protein L30 | -0.0225747 |
