| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Olanzapine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Olanzapine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0873919 |
| SMAD3 | SMAD family member 3 | 0.0865678 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0857695 |
| PCBP2 | poly(rC) binding protein 2 | 0.0812737 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0782386 |
| FN1 | fibronectin 1 | 0.0692378 |
| TGM2 | transglutaminase 2 | 0.0628404 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0556543 |
| SEPTIN9 | septin 9 | 0.05462 |
| NTN4 | netrin 4 | 0.0530264 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0529849 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0526768 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.052018 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0491 |
| INTS6 | integrator complex subunit 6 | 0.0463934 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0459035 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0458408 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0455329 |
| AADAC | arylacetamide deacetylase | 0.0425775 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0425046 |
| VEGFA | vascular endothelial growth factor A | 0.0423971 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0423446 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0412511 |
| NAV2 | neuron navigator 2 | 0.0387433 |
| KSR1 | kinase suppressor of ras 1 | 0.0380642 |
| LOXL2 | lysyl oxidase-like 2 | 0.037583 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0367237 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0366707 |
| ECE1 | endothelin converting enzyme 1 | 0.0358787 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0348416 |
| FLNA | filamin A, alpha | 0.034076 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0339438 |
| MYO10 | myosin X | 0.0331075 |
| STK38L | serine/threonine kinase 38 like | 0.0326535 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0322298 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0319492 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0313251 |
| CEP250 | centrosomal protein 250kDa | 0.0311801 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0311761 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0311222 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0308537 |
| HMGA2 | high mobility group AT-hook 2 | 0.0305653 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0298214 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0295663 |
| PLEC | plectin | 0.0281241 |
| MCL1 | myeloid cell leukemia 1 | 0.0277163 |
| ATXN1 | ataxin 1 | 0.0276793 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0273441 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0273346 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0263083 |
| RHCG | Rh family, C glycoprotein | 0.0259641 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.025922 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0257792 |
| ASPH | aspartate beta-hydroxylase | 0.0252698 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0249272 |
| TGFB1 | transforming growth factor, beta 1 | 0.0248861 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0240635 |
| CTBP2 | C-terminal binding protein 2 | 0.0240282 |
| COL7A1 | collagen, type VII, alpha 1 | 0.024027 |
| CPNE1 | copine I | 0.0238011 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0235372 |
| IFI44L | interferon-induced protein 44-like | 0.0233574 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0231751 |
| IL1R1 | interleukin 1 receptor, type I | 0.0230497 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0229338 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0220533 |
| BRD2 | bromodomain containing 2 | 0.0216302 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0215681 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0215669 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0215603 |
| WLS | wntless Wnt ligand secretion mediator | 0.0215521 |
| NEBL | nebulette | 0.0214551 |
| PRKCA | protein kinase C, alpha | 0.0211452 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0211335 |
| CORO1C | coronin, actin binding protein, 1C | 0.0206885 |
| NOTCH2 | notch 2 | 0.0200611 |
| HDAC4 | histone deacetylase 4 | 0.0200422 |
| RNF144A | ring finger protein 144A | 0.0199366 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0198313 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0196142 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0192428 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0191649 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0191609 |
| YBX1 | Y box binding protein 1 | 0.0191591 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0188983 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0188606 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0186917 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0185647 |
| PKM | pyruvate kinase, muscle | 0.0184417 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0184364 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0184284 |
| DIAPH1 | diaphanous-related formin 1 | 0.0181272 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0179544 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0179263 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.017845 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0178065 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0177727 |
| RCOR1 | REST corepressor 1 | 0.0177348 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0175063 |
| SIK3 | SIK family kinase 3 | 0.0174504 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.239545 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.203446 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.172914 |
| TMSB10 | thymosin beta 10 | -0.167918 |
| OSMR | oncostatin M receptor | -0.117499 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.113203 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.112851 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.102405 |
| STC1 | stanniocalcin 1 | -0.0952075 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0942274 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0897917 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0842866 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0827748 |
| RBM39 | RNA binding motif protein 39 | -0.0784855 |
| USP34 | ubiquitin specific peptidase 34 | -0.0747766 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0743292 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0694587 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0690642 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0657546 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0657508 |
| IER3 | immediate early response 3 | -0.0656855 |
| GOLGA4 | golgin A4 | -0.0653416 |
| NRG1 | neuregulin 1 | -0.0606071 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0602027 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0594913 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0594233 |
| LOX | lysyl oxidase | -0.0590369 |
| VIM | vimentin | -0.0587851 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0577733 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0557764 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0543726 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0522208 |
| S100A6 | S100 calcium binding protein A6 | -0.0515672 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0498724 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0492624 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0486517 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0482677 |
| PTMA | prothymosin, alpha | -0.0477849 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0475174 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0472987 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0468628 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0468236 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0461925 |
| IL1B | interleukin 1, beta | -0.0457451 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.045565 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0452963 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0450225 |
| TMEM165 | transmembrane protein 165 | -0.0439929 |
| CDCP1 | CUB domain containing protein 1 | -0.042989 |
| CDH13 | cadherin 13 | -0.0427285 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0416767 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0416722 |
| EREG | epiregulin | -0.0414739 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0411568 |
| MEF2A | myocyte enhancer factor 2A | -0.0404752 |
| RAI14 | retinoic acid induced 14 | -0.0399956 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0398867 |
| NF1 | neurofibromin 1 | -0.0386443 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0382602 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0381237 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.037675 |
| TMEM263 | transmembrane protein 263 | -0.0375522 |
| ENOSF1 | enolase superfamily member 1 | -0.0371551 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0366973 |
| RPLP1 | ribosomal protein, large, P1 | -0.0366068 |
| PGK1 | phosphoglycerate kinase 1 | -0.0365476 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0364357 |
| SNX9 | sorting nexin 9 | -0.0362541 |
| RPL35A | ribosomal protein L35a | -0.036077 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0359541 |
| ETV6 | ets variant 6 | -0.0355924 |
| HLA-B | major histocompatibility complex, class I, B | -0.035578 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0354067 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0353083 |
| GNAS | GNAS complex locus | -0.0348903 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0348768 |
| RUNX2 | runt-related transcription factor 2 | -0.0346169 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0342327 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0336378 |
| MTSS1 | metastasis suppressor 1 | -0.0334278 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.033363 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0333445 |
| DENND4A | DENN/MADD domain containing 4A | -0.0330604 |
| ENO1 | enolase 1, (alpha) | -0.0326811 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0326365 |
| RPS24 | ribosomal protein S24 | -0.0324731 |
| NGLY1 | N-glycanase 1 | -0.0323949 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0321888 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0321422 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0320873 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0320594 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0319185 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0317261 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0316974 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0315239 |
| GPC6 | glypican 6 | -0.0314092 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0311601 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0310771 |
| RPL34 | ribosomal protein L34 | -0.0310081 |
| VRK2 | vaccinia related kinase 2 | -0.0309536 |
