| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Olanzapine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Olanzapine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.219024 |
| VIM | vimentin | 0.112127 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0988427 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0899047 |
| WWOX | WW domain containing oxidoreductase | 0.0824815 |
| MCL1 | myeloid cell leukemia 1 | 0.0799382 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0608125 |
| FLNA | filamin A, alpha | 0.0596834 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0518472 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.051721 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0516251 |
| FNDC3B | fibronectin type III domain containing 3B | 0.050229 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.050077 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0499816 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0472699 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0472522 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0425021 |
| ATXN1 | ataxin 1 | 0.0414485 |
| RPS12 | ribosomal protein S12 | 0.0396721 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0390818 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.038269 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0380705 |
| FAM107B | family with sequence similarity 107, member B | 0.037652 |
| BMP6 | bone morphogenetic protein 6 | 0.0358951 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0332493 |
| PRELID2 | PRELI domain containing 2 | 0.0325561 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0318629 |
| RRM2 | ribonucleotide reductase M2 | 0.0314815 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0308186 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0307472 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0307209 |
| RPL23 | ribosomal protein L23 | 0.0306658 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0300146 |
| FHIT | fragile histidine triad | 0.0289972 |
| PDE8A | phosphodiesterase 8A | 0.0282347 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.027898 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0269124 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0266319 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0263999 |
| DOCK5 | dedicator of cytokinesis 5 | 0.026281 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0261393 |
| MSN | moesin | 0.025242 |
| RPS3 | ribosomal protein S3 | 0.0251751 |
| RAD51B | RAD51 paralog B | 0.0251287 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0248866 |
| FMNL2 | formin-like 2 | 0.0247795 |
| RPS4X | ribosomal protein S4, X-linked | 0.0244391 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.0242053 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0241573 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0238929 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0235153 |
| TPM3 | tropomyosin 3 | 0.0224575 |
| CMIP | c-Maf inducing protein | 0.0217242 |
| RPL13A | ribosomal protein L13a | 0.0215615 |
| PRKCE | protein kinase C, epsilon | 0.0211148 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0210243 |
| INTS6 | integrator complex subunit 6 | 0.0209433 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0208888 |
| CABIN1 | calcineurin binding protein 1 | 0.0207697 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0206714 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0205173 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0204619 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0204244 |
| CEP250 | centrosomal protein 250kDa | 0.02041 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0203502 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0200904 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.019963 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0199561 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.01994 |
| SMAD3 | SMAD family member 3 | 0.0199019 |
| CPNE1 | copine I | 0.0198831 |
| SEPTIN9 | septin 9 | 0.0198561 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0197983 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0197725 |
| RPL7 | ribosomal protein L7 | 0.0194958 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0194098 |
| GPC6 | glypican 6 | 0.0192053 |
| UTRN | utrophin | 0.019159 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0189561 |
| PLEC | plectin | 0.0189055 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0184223 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0183253 |
| RPL11 | ribosomal protein L11 | 0.0182018 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0180366 |
| EFNA5 | ephrin-A5 | 0.0180039 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0178863 |
| HYOU1 | hypoxia up-regulated 1 | 0.017834 |
| RPS7 | ribosomal protein S7 | 0.0174216 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0174173 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0173195 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0172395 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0170797 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0169332 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0169107 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0165906 |
| FAT1 | FAT atypical cadherin 1 | 0.0165605 |
| ACLY | ATP citrate lyase | 0.0165375 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0164379 |
| KYNU | kynureninase | 0.0164097 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0163984 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.405073 |
| TXNRD1 | thioredoxin reductase 1 | -0.171662 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.146191 |
| IGF2 | insulin-like growth factor 2 | -0.138275 |
| ACTG1 | actin gamma 1 | -0.12646 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.123146 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0742741 |
| ERBIN | erbb2 interacting protein | -0.0686748 |
| POTEF | POTE ankyrin domain family, member F | -0.0648698 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0616791 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0572998 |
| S100A6 | S100 calcium binding protein A6 | -0.0531673 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.052467 |
| IER3 | immediate early response 3 | -0.0508459 |
| S100A10 | S100 calcium binding protein A10 | -0.0504242 |
| TPM4 | tropomyosin 4 | -0.0499998 |
| EGR1 | early growth response 1 | -0.0499074 |
| TMSB10 | thymosin beta 10 | -0.0480391 |
| OSMR | oncostatin M receptor | -0.047898 |
| GRAMD1B | GRAM domain containing 1B | -0.0454391 |
| HDAC9 | histone deacetylase 9 | -0.0453947 |
| MT2A | metallothionein 2A | -0.0451666 |
| RPL35A | ribosomal protein L35a | -0.0434035 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0429313 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0400545 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0384137 |
| CAVIN1 | caveolae associated protein 1 | -0.0380523 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0380215 |
| RBM39 | RNA binding motif protein 39 | -0.0377607 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0371698 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0351279 |
| GLG1 | golgi glycoprotein 1 | -0.0344194 |
| AK1 | adenylate kinase 1 | -0.0335811 |
| STC1 | stanniocalcin 1 | -0.0334442 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0333867 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0331258 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.03276 |
| PYGL | phosphorylase, glycogen, liver | -0.0325179 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.031623 |
| CFDP1 | craniofacial development protein 1 | -0.0311386 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0309352 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0303633 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0303583 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0303069 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0301883 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0293272 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0288565 |
| RBM25 | RNA binding motif protein 25 | -0.0287127 |
| NAV3 | neuron navigator 3 | -0.0284075 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0280927 |
| CD99 | CD99 molecule | -0.0275588 |
| RAB10 | RAB10, member RAS oncogene family | -0.0275018 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0270625 |
| SNX14 | sorting nexin 14 | -0.0270487 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0264463 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0264403 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0261934 |
| KIF5B | kinesin family member 5B | -0.0261843 |
| RPS6 | ribosomal protein S6 | -0.0256923 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0253182 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0253082 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0248298 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0247209 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0245206 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0243749 |
| RIN2 | Ras and Rab interactor 2 | -0.0242199 |
| ZNF207 | zinc finger protein 207 | -0.0238311 |
| ATXN3 | ataxin 3 | -0.0233516 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0233221 |
| RHOA | ras homolog family member A | -0.0223606 |
| PTMA | prothymosin, alpha | -0.0222364 |
| CENPF | centromere protein F, 350/400kDa | -0.0220573 |
| GNAS | GNAS complex locus | -0.0220089 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0219996 |
| INO80 | INO80 complex subunit | -0.0219441 |
| CA2 | carbonic anhydrase II | -0.0219261 |
| RPS15 | ribosomal protein S15 | -0.02186 |
| RPL34 | ribosomal protein L34 | -0.021854 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.021599 |
| DENND5B | DENN/MADD domain containing 5B | -0.0215981 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0215693 |
| AHNAK | AHNAK nucleoprotein | -0.021531 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0214919 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0213787 |
| FBXO11 | F-box protein 11 | -0.0213469 |
| ETFA | electron-transfer-flavoprotein, alpha polypeptide | -0.0211918 |
| RPL8 | ribosomal protein L8 | -0.0210721 |
| YY1 | YY1 transcription factor | -0.0210452 |
| S100A9 | S100 calcium binding protein A9 | -0.0209142 |
| NOP58 | NOP58 ribonucleoprotein | -0.0207716 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0206535 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.020644 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0205485 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0205287 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0203202 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0202861 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0202538 |
| HLA-B | major histocompatibility complex, class I, B | -0.0200896 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0200614 |
| BICC1 | BicC family RNA binding protein 1 | -0.0196817 |
