| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Olanzapine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Olanzapine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.122554 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.114361 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.110257 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.103976 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0902439 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0864359 |
| VEGFA | vascular endothelial growth factor A | 0.077929 |
| DSPP | dentin sialophosphoprotein | 0.0685581 |
| CANX | calnexin | 0.0629207 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0593059 |
| PLEC | plectin | 0.0577922 |
| TPM3 | tropomyosin 3 | 0.0508031 |
| FLNA | filamin A, alpha | 0.0494691 |
| MSN | moesin | 0.0480638 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0475451 |
| VIM | vimentin | 0.0443453 |
| TMF1 | TATA element modulatory factor 1 | 0.0440753 |
| KRT18 | keratin 18, type I | 0.0423405 |
| FBXO32 | F-box protein 32 | 0.0407329 |
| MCL1 | myeloid cell leukemia 1 | 0.0407246 |
| RAI14 | retinoic acid induced 14 | 0.0376933 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0363319 |
| PCBP2 | poly(rC) binding protein 2 | 0.0362501 |
| HDGF | hepatoma-derived growth factor | 0.034963 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.034774 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0347419 |
| MX1 | MX dynamin-like GTPase 1 | 0.0346335 |
| FLNB | filamin B, beta | 0.0340147 |
| GOLGB1 | golgin B1 | 0.0337168 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0327302 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0323368 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0319861 |
| PGBD5 | piggyBac transposable element derived 5 | 0.031781 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0313022 |
| RPS12 | ribosomal protein S12 | 0.0308983 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0306209 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0303615 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.030344 |
| NAV2 | neuron navigator 2 | 0.0301552 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0294611 |
| PTMA | prothymosin, alpha | 0.0292505 |
| BRD2 | bromodomain containing 2 | 0.0291523 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0279507 |
| JUP | junction plakoglobin | 0.0278522 |
| RCOR1 | REST corepressor 1 | 0.0271712 |
| SEPTIN9 | septin 9 | 0.0271642 |
| RAD51B | RAD51 paralog B | 0.0271194 |
| CALR | calreticulin | 0.0266627 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0261888 |
| CTBP2 | C-terminal binding protein 2 | 0.0254281 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0252251 |
| STC2 | stanniocalcin 2 | 0.025082 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0250748 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0245892 |
| BBX | bobby sox homolog (Drosophila) | 0.0241496 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0239276 |
| GRB10 | growth factor receptor-bound protein 10 | 0.023874 |
| RNF213 | ring finger protein 213 | 0.0235617 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0233107 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0232939 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0232257 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0230352 |
| RPL14 | ribosomal protein L14 | 0.0227621 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0226746 |
| ATF4 | activating transcription factor 4 | 0.022414 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0223844 |
| RPL13A | ribosomal protein L13a | 0.0222032 |
| FNBP4 | formin binding protein 4 | 0.0220819 |
| MAP1B | microtubule-associated protein 1B | 0.0219885 |
| XPO1 | exportin 1 | 0.0217703 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0216082 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0215556 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0212845 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0211078 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0208977 |
| CLIC4 | chloride intracellular channel 4 | 0.0207971 |
| HLA-A | major histocompatibility complex, class I, A | 0.0207008 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0204704 |
| TUFT1 | tuftelin 1 | 0.0203217 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.02022 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0199995 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.019802 |
| SET | SET nuclear proto-oncogene | 0.019643 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0194679 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0192891 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0192296 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0190735 |
| DTNA | dystrobrevin, alpha | 0.0190299 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0189795 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0187387 |
| EZR | ezrin | 0.0187038 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0184868 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0184336 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0182858 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.0182256 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0181417 |
| FMNL2 | formin-like 2 | 0.0180694 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0178166 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0177632 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0176465 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.33339 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.254276 |
| ASPH | aspartate beta-hydroxylase | -0.136132 |
| ACTG1 | actin gamma 1 | -0.13264 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.116567 |
| TMSB10 | thymosin beta 10 | -0.109192 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0944614 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0935114 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0895534 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0872888 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0829906 |
| RPL34 | ribosomal protein L34 | -0.0808 |
| S100A6 | S100 calcium binding protein A6 | -0.0759231 |
| POTEF | POTE ankyrin domain family, member F | -0.0707583 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0667992 |
| NDRG1 | N-myc downstream regulated 1 | -0.0654891 |
| CD2AP | CD2-associated protein | -0.064986 |
| LMO7 | LIM domain 7 | -0.0646652 |
| RPL35A | ribosomal protein L35a | -0.0646008 |
| S100A10 | S100 calcium binding protein A10 | -0.0645281 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0640206 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0636578 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0620284 |
| HMGA1 | high mobility group AT-hook 1 | -0.0614855 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0591798 |
| TFG | TRK-fused gene | -0.0569598 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0565262 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0535939 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0535546 |
| FN1 | fibronectin 1 | -0.0509437 |
| FAM3C | family with sequence similarity 3, member C | -0.0502566 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.049141 |
| PGK1 | phosphoglycerate kinase 1 | -0.0485847 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0477471 |
| RASA2 | RAS p21 protein activator 2 | -0.0475822 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0468127 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0462974 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.046268 |
| ANXA2 | annexin A2 | -0.0459423 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0458154 |
| RPL32 | ribosomal protein L32 | -0.0448386 |
| ZNF292 | zinc finger protein 292 | -0.043565 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0429549 |
| RBM39 | RNA binding motif protein 39 | -0.0427205 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0420825 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0409696 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0396597 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0394148 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.03931 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0387774 |
| DSG2 | desmoglein 2 | -0.0386034 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0379598 |
| CCNI | cyclin I | -0.0379138 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.037842 |
| RACK1 | receptor for activated C kinase 1 | -0.0376449 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0372675 |
| RPL8 | ribosomal protein L8 | -0.0371951 |
| RHEB | Ras homolog enriched in brain | -0.0371291 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0370424 |
| CDC73 | cell division cycle 73 | -0.0370388 |
| TMEM123 | transmembrane protein 123 | -0.0370181 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0365692 |
| UBC | ubiquitin C | -0.0365632 |
| RPLP0 | ribosomal protein, large, P0 | -0.0365385 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0364232 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0361881 |
| EPCAM | epithelial cell adhesion molecule | -0.035978 |
| ARF1 | ADP-ribosylation factor 1 | -0.0357116 |
| FNDC3B | fibronectin type III domain containing 3B | -0.034753 |
| TMEM263 | transmembrane protein 263 | -0.0346953 |
| TXNRD1 | thioredoxin reductase 1 | -0.034402 |
| RNF145 | ring finger protein 145 | -0.0343791 |
| SDC4 | syndecan 4 | -0.0341984 |
| CDK17 | cyclin-dependent kinase 17 | -0.0340777 |
| FAM162A | family with sequence similarity 162, member A | -0.034022 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0336793 |
| USP3 | ubiquitin specific peptidase 3 | -0.0335204 |
| OSMR | oncostatin M receptor | -0.0333434 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0333367 |
| GNAS | GNAS complex locus | -0.0327699 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0327541 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0324809 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0324246 |
| RPS23 | ribosomal protein S23 | -0.0323404 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0322774 |
| ECT2 | epithelial cell transforming 2 | -0.0316741 |
| LMAN1 | lectin, mannose-binding, 1 | -0.03122 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0311783 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0306851 |
| KRT7 | keratin 7, type II | -0.0304519 |
| RPL30 | ribosomal protein L30 | -0.0304375 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0304346 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.030358 |
| QKI | QKI, KH domain containing, RNA binding | -0.0303386 |
| TOP1 | topoisomerase (DNA) I | -0.0300802 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0300782 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0298581 |
| NCKAP1 | NCK-associated protein 1 | -0.0298136 |
| CCND1 | cyclin D1 | -0.0297588 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0296797 |
