| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Olanzapine perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Olanzapine_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.199442 |
| PDE10A | phosphodiesterase 10A | 0.160808 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.159333 |
| IGF2 | insulin-like growth factor 2 | 0.15834 |
| RORA | RAR-related orphan receptor A | 0.157823 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.145866 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.138834 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.132593 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.127962 |
| RUNX1 | runt-related transcription factor 1 | 0.123115 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.121359 |
| PRELID2 | PRELI domain containing 2 | 0.114505 |
| EGFR | epidermal growth factor receptor | 0.111162 |
| SYT1 | synaptotagmin I | 0.108877 |
| HMGA2 | high mobility group AT-hook 2 | 0.0983796 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0956958 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0950512 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0894403 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0866848 |
| NAV2 | neuron navigator 2 | 0.0807886 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0773347 |
| EFNA5 | ephrin-A5 | 0.0758976 |
| COPA | coatomer protein complex, subunit alpha | 0.0755483 |
| TBC1D22A | TBC1 domain family, member 22A | 0.075426 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0744776 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0728871 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0697237 |
| CMIP | c-Maf inducing protein | 0.0691126 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0668424 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0665329 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0660547 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0655888 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0651414 |
| GOLGA4 | golgin A4 | 0.0650272 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0647723 |
| CANX | calnexin | 0.0647717 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.063195 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0596401 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0565704 |
| MYO1E | myosin IE | 0.0537623 |
| PRKCA | protein kinase C, alpha | 0.0527756 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0521639 |
| INTS6 | integrator complex subunit 6 | 0.0503538 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0502403 |
| PDE8A | phosphodiesterase 8A | 0.0486479 |
| HDLBP | high density lipoprotein binding protein | 0.0485897 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0485464 |
| SBF2 | SET binding factor 2 | 0.0483203 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0481486 |
| SMYD3 | SET and MYND domain containing 3 | 0.0477932 |
| NDRG1 | N-myc downstream regulated 1 | 0.0472803 |
| HM13 | histocompatibility (minor) 13 | 0.0452051 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0435614 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0423656 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0419291 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0409962 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0373471 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0368443 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0360167 |
| SLTM | SAFB-like, transcription modulator | 0.0358173 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.035665 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.035628 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0346714 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0296216 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0293482 |
| GPC6 | glypican 6 | 0.0290319 |
| FNIP1 | folliculin interacting protein 1 | 0.0285968 |
| PARD3 | par-3 family cell polarity regulator | 0.0255461 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0241412 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0239601 |
| ANO6 | anoctamin 6 | 0.0235461 |
| MCL1 | myeloid cell leukemia 1 | 0.023359 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0222947 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0217616 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0217487 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0207365 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0202588 |
| COL5A2 | collagen, type V, alpha 2 | 0.0174567 |
| PTK2 | protein tyrosine kinase 2 | 0.0156731 |
| TOP1 | topoisomerase (DNA) I | 0.0156252 |
| DIAPH1 | diaphanous-related formin 1 | 0.0154457 |
| KYNU | kynureninase | 0.0154422 |
| RACK1 | receptor for activated C kinase 1 | 0.0143629 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0129861 |
| TNS3 | tensin 3 | 0.0128007 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0125155 |
| STC1 | stanniocalcin 1 | 0.0123655 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0119792 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.00988107 |
| RPLP1 | ribosomal protein, large, P1 | 0.00933113 |
| NRXN3 | neurexin 3 | 0.0080675 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.00757016 |
| EGR1 | early growth response 1 | 0.00668298 |
| FOXP1 | forkhead box P1 | 0.00650383 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.00591477 |
| PATJ | PATJ crumbs cell polarity complex component | 0.00551346 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.00390212 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00330799 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00311745 |
| RPLP0 | ribosomal protein, large, P0 | 0.0029621 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.184325 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.167949 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.155256 |
| RPL35A | ribosomal protein L35a | -0.121296 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.108914 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.105497 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.102567 |
| FN1 | fibronectin 1 | -0.10254 |
| RPS6 | ribosomal protein S6 | -0.100813 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.098937 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0987871 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0949726 |
| RPL37A | ribosomal protein L37a | -0.0928216 |
| EXT1 | exostosin glycosyltransferase 1 | -0.090349 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0812958 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0764353 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0759364 |
| INHBA | inhibin, beta A | -0.0720693 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0715286 |
| PTMA | prothymosin, alpha | -0.0714726 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0695736 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0691139 |
| USP34 | ubiquitin specific peptidase 34 | -0.0664953 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0664351 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0653746 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0643656 |
| PKM | pyruvate kinase, muscle | -0.06276 |
| B2M | beta-2-microglobulin | -0.0618516 |
| LMO7 | LIM domain 7 | -0.0605887 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0600412 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0568746 |
| MED13L | mediator complex subunit 13-like | -0.0560775 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0559059 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0551545 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0547207 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0541568 |
| DST | dystonin | -0.0529607 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0521169 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0509589 |
| JMJD1C | jumonji domain containing 1C | -0.0508355 |
| YBX3 | Y box binding protein 3 | -0.0504138 |
| RNF213 | ring finger protein 213 | -0.0485738 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0485098 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0478616 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0461961 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0442277 |
| HLA-B | major histocompatibility complex, class I, B | -0.0440316 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0436366 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0434288 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0402001 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0385045 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0376277 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0370919 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0363632 |
| PGK1 | phosphoglycerate kinase 1 | -0.0346124 |
| ENO1 | enolase 1, (alpha) | -0.0345745 |
| VIM | vimentin | -0.0340397 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0339057 |
| NF1 | neurofibromin 1 | -0.0331303 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0327006 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0322743 |
| RIGI | RNA sensor RIG-I | -0.0317875 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0315832 |
| ERBIN | erbb2 interacting protein | -0.0310675 |
| ASPH | aspartate beta-hydroxylase | -0.0298142 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0282186 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0280015 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.027714 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0273375 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0272896 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0269872 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0265902 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0253684 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0251825 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0242455 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0235887 |
| COL6A1 | collagen, type VI, alpha 1 | -0.022559 |
| MT2A | metallothionein 2A | -0.0219064 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0217256 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0217127 |
| MED13 | mediator complex subunit 13 | -0.021103 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0206764 |
| NABP1 | nucleic acid binding protein 1 | -0.0198109 |
| TPM4 | tropomyosin 4 | -0.0193849 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0193576 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.018922 |
| TXNRD1 | thioredoxin reductase 1 | -0.0188496 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0184914 |
| CNKSR3 | CNKSR family member 3 | -0.0179797 |
| PCBP2 | poly(rC) binding protein 2 | -0.0176223 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0170695 |
| LAMA4 | laminin, alpha 4 | -0.0169424 |
| CD44 | CD44 molecule (Indian blood group) | -0.0166393 |
| RPL23 | ribosomal protein L23 | -0.0157324 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0146204 |
| GPHN | gephyrin | -0.0134436 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0130704 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0125827 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0124109 |
| CUX1 | cut-like homeobox 1 | -0.0123434 |
