| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Olanzapine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Olanzapine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NTM | neurotrimin | 0.117916 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0814523 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0753893 |
| TENM3 | teneurin transmembrane protein 3 | 0.0736846 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.06929 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0622484 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0576405 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0571991 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0507171 |
| PCDH7 | protocadherin 7 | 0.0499768 |
| FAT1 | FAT atypical cadherin 1 | 0.0430779 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0387212 |
| FOXG1 | forkhead box G1 | 0.0377154 |
| ZNF608 | zinc finger protein 608 | 0.0356548 |
| ITSN2 | intersectin 2 | 0.0354328 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0351703 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0345154 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0341814 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0330771 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.032708 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0326942 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0318822 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.031822 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0315768 |
| DIDO1 | death inducer-obliterator 1 | 0.0312263 |
| ZNF638 | zinc finger protein 638 | 0.0301215 |
| HDAC9 | histone deacetylase 9 | 0.029851 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0295332 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0295085 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0292536 |
| WWOX | WW domain containing oxidoreductase | 0.0289192 |
| CFL2 | cofilin 2 (muscle) | 0.0288855 |
| ZNF146 | zinc finger protein 146 | 0.0285815 |
| DST | dystonin | 0.0280781 |
| EVI5 | ecotropic viral integration site 5 | 0.0279305 |
| RPL3 | ribosomal protein L3 | 0.02773 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0273874 |
| EXOC4 | exocyst complex component 4 | 0.0273271 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0272866 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0272664 |
| TAF4 | TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa | 0.0262225 |
| CCN2 | cellular communication network factor 2 | 0.0261129 |
| BRD2 | bromodomain containing 2 | 0.025976 |
| TGFB2 | transforming growth factor, beta 2 | 0.0255568 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0255421 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0253682 |
| XPO1 | exportin 1 | 0.0252151 |
| FLNA | filamin A, alpha | 0.0251767 |
| PCDH18 | protocadherin 18 | 0.0249636 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0247851 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0247199 |
| UTRN | utrophin | 0.0246829 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0246739 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0245835 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0242439 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0240873 |
| PCM1 | pericentriolar material 1 | 0.0240424 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0240231 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0240178 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0240075 |
| CTBP2 | C-terminal binding protein 2 | 0.0239517 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0237395 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0234445 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0233168 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.023268 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.023216 |
| VIM | vimentin | 0.0230015 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0229586 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0228329 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.02248 |
| COL5A2 | collagen, type V, alpha 2 | 0.0224435 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0222934 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0222523 |
| TPM3 | tropomyosin 3 | 0.0220506 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0218283 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0218241 |
| MACROD2 | MACRO domain containing 2 | 0.021742 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0215369 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | 0.0213239 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0211298 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0210008 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0208699 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0208382 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0207215 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0206331 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0202838 |
| CEP250 | centrosomal protein 250kDa | 0.0202342 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.019964 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.019818 |
| TAF3 | TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa | 0.0197999 |
| HADHB | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit | 0.0197602 |
| TRIM2 | tripartite motif containing 2 | 0.0195242 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0195201 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0194742 |
| BNC2 | basonuclin 2 | 0.0194733 |
| YBX1 | Y box binding protein 1 | 0.0194713 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0194093 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) | 0.0194093 |
| NFIB | nuclear factor I/B | 0.0194034 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0194002 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.208614 |
| PTMA | prothymosin, alpha | -0.141799 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0902019 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0886672 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0879359 |
| TMSB10 | thymosin beta 10 | -0.0857693 |
| RPS16 | ribosomal protein S16 | -0.0828678 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0826179 |
| AHNAK | AHNAK nucleoprotein | -0.0771026 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0715265 |
| SPAG9 | sperm associated antigen 9 | -0.0702081 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0689435 |
| ITGAV | integrin, alpha V | -0.0669355 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0646228 |
| PHIP | pleckstrin homology domain interacting protein | -0.0629973 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0622559 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0602243 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.059866 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.059758 |
| NRG1 | neuregulin 1 | -0.0591189 |
| ZNF217 | zinc finger protein 217 | -0.058476 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0578542 |
| PCDH9 | protocadherin 9 | -0.056756 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0564215 |
| GPC3 | glypican 3 | -0.0552051 |
| EMP1 | epithelial membrane protein 1 | -0.0529782 |
| RHEB | Ras homolog enriched in brain | -0.0512213 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0510078 |
| STAG2 | stromal antigen 2 | -0.0495811 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0493044 |
| ACTG1 | actin gamma 1 | -0.0483181 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0479406 |
| MAP4 | microtubule-associated protein 4 | -0.0479056 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0475255 |
| GNAS | GNAS complex locus | -0.047002 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0462906 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0452551 |
| PLPP1 | phospholipid phosphatase 1 | -0.0452362 |
| SNX6 | sorting nexin 6 | -0.044792 |
| MKI67 | marker of proliferation Ki-67 | -0.0439656 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0437296 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.043261 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0427738 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.042646 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.042344 |
| B2M | beta-2-microglobulin | -0.0422032 |
| ANXA2 | annexin A2 | -0.0416413 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0411986 |
| PFN1 | profilin 1 | -0.0409921 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0409545 |
| RBM39 | RNA binding motif protein 39 | -0.0404906 |
| TMSB4X | thymosin beta 4, X-linked | -0.0404516 |
| COL1A2 | collagen, type I, alpha 2 | -0.0402552 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0389585 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0385699 |
| MEIS2 | Meis homeobox 2 | -0.0382763 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0382479 |
| RPS21 | ribosomal protein S21 | -0.0382138 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0380965 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0380446 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0378306 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0375699 |
| CBX3 | chromobox homolog 3 | -0.0374528 |
| H1-0 | H1.0 linker histone | -0.036676 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0366461 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0365682 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0365244 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0365208 |
| FAM171B | family with sequence similarity 171, member B | -0.0364433 |
| NOP58 | NOP58 ribonucleoprotein | -0.0359015 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0354987 |
| TUT4 | terminal uridylyl transferase 4 | -0.0353879 |
| CENPE | centromere protein E, 312kDa | -0.0352696 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0346505 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0345339 |
| CALR | calreticulin | -0.0344396 |
| SRP54 | signal recognition particle 54kDa | -0.03424 |
| RPL26 | ribosomal protein L26 | -0.0341466 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0340037 |
| SHROOM3 | shroom family member 3 | -0.0339883 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.03373 |
| RPS8 | ribosomal protein S8 | -0.0337194 |
| RPL35A | ribosomal protein L35a | -0.0331055 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0330608 |
| RTN4 | reticulon 4 | -0.0329002 |
| RAD21 | RAD21 homolog (S. pombe) | -0.032892 |
| CAVIN1 | caveolae associated protein 1 | -0.0326481 |
| COL3A1 | collagen, type III, alpha 1 | -0.0326287 |
| TOX | thymocyte selection-associated high mobility group box | -0.0325899 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0325857 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0320317 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0319876 |
| DEK | DEK proto-oncogene | -0.031574 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0315626 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0311844 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0308516 |
| TMEM41B | transmembrane protein 41B | -0.0307568 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.03068 |
| ARF1 | ADP-ribosylation factor 1 | -0.0305516 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.030028 |
