| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Olanzapine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Olanzapine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.282391 |
| VIM | vimentin | 0.122078 |
| GLIS3 | GLIS family zinc finger 3 | 0.115531 |
| HMGA2 | high mobility group AT-hook 2 | 0.0959354 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0926812 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0847133 |
| KYNU | kynureninase | 0.08091 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0793862 |
| EXT1 | exostosin glycosyltransferase 1 | 0.068788 |
| LDHA | lactate dehydrogenase A | 0.0686335 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0656929 |
| PLIN2 | perilipin 2 | 0.0633267 |
| RNF213 | ring finger protein 213 | 0.0603865 |
| HDAC9 | histone deacetylase 9 | 0.0578343 |
| BICC1 | BicC family RNA binding protein 1 | 0.0553514 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0541744 |
| C3 | complement component 3 | 0.0521788 |
| SMAD3 | SMAD family member 3 | 0.0494661 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0480923 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0474419 |
| VEGFA | vascular endothelial growth factor A | 0.0471255 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0469648 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0465787 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.043501 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0425056 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0403645 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0395938 |
| VCAN | versican | 0.038728 |
| HLA-A | major histocompatibility complex, class I, A | 0.0384938 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0374473 |
| RND3 | Rho family GTPase 3 | 0.037211 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0362358 |
| STC1 | stanniocalcin 1 | 0.0358378 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0354124 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0350357 |
| PGK1 | phosphoglycerate kinase 1 | 0.0341104 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.034009 |
| INHBA | inhibin, beta A | 0.0332481 |
| ZNF608 | zinc finger protein 608 | 0.0327235 |
| SFTPA2 | surfactant protein A2 | 0.0318792 |
| FBXO32 | F-box protein 32 | 0.0309438 |
| NRP1 | neuropilin 1 | 0.0307458 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0302479 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.030237 |
| TGM2 | transglutaminase 2 | 0.0299173 |
| ADM | adrenomedullin | 0.0298601 |
| CTSB | cathepsin B | 0.0297643 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0282707 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0279386 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | 0.0278544 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0259968 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0247172 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.024344 |
| PMP22 | peripheral myelin protein 22 | 0.0243025 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0240918 |
| HLA-E | major histocompatibility complex, class I, E | 0.0236545 |
| SH3BP4 | SH3-domain binding protein 4 | 0.0235255 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0232864 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0231085 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0225262 |
| EHBP1 | EH domain binding protein 1 | 0.0224949 |
| TUBB | tubulin, beta class I | 0.0219981 |
| KSR1 | kinase suppressor of ras 1 | 0.0218569 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0217131 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0215624 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0214926 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0210063 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0209927 |
| IL6ST | interleukin 6 signal transducer | 0.0209868 |
| NTN4 | netrin 4 | 0.0209591 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0208914 |
| EFNA5 | ephrin-A5 | 0.0208538 |
| CEP250 | centrosomal protein 250kDa | 0.0208199 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0207088 |
| SEPTIN9 | septin 9 | 0.0204749 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0201641 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0197147 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0194837 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.019442 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0194328 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0193297 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0192304 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.018916 |
| TMEM164 | transmembrane protein 164 | 0.0188679 |
| FLNA | filamin A, alpha | 0.0188481 |
| CLMP | CXADR-like membrane protein | 0.0188356 |
| CDK17 | cyclin-dependent kinase 17 | 0.0188225 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0184258 |
| ANGPTL4 | angiopoietin-like 4 | 0.0184016 |
| DIAPH3 | diaphanous-related formin 3 | 0.0183043 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0182929 |
| ATXN1 | ataxin 1 | 0.0182282 |
| RPS4X | ribosomal protein S4, X-linked | 0.0179211 |
| FHIT | fragile histidine triad | 0.0176426 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0174466 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0173505 |
| FLNB | filamin B, beta | 0.0172667 |
| RASAL2 | RAS protein activator like 2 | 0.0170345 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0170303 |
| LOX | lysyl oxidase | 0.0169085 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.169483 |
| FRMD4A | FERM domain containing 4A | -0.114601 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.108312 |
| TMSB10 | thymosin beta 10 | -0.108296 |
| PDE10A | phosphodiesterase 10A | -0.105471 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0906468 |
| UBC | ubiquitin C | -0.0858146 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0802572 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0800067 |
| RPS27A | ribosomal protein S27a | -0.0797844 |
| CADM1 | cell adhesion molecule 1 | -0.0786733 |
| AHNAK | AHNAK nucleoprotein | -0.0782844 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0744229 |
| NAV2 | neuron navigator 2 | -0.0741238 |
| RPL23 | ribosomal protein L23 | -0.0724281 |
| ZNF292 | zinc finger protein 292 | -0.0686963 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0635953 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0606979 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0606781 |
| ENO1 | enolase 1, (alpha) | -0.0594265 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0574943 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0562464 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0532545 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0530536 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0528473 |
| RTN4 | reticulon 4 | -0.052244 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0517155 |
| COL1A1 | collagen, type I, alpha 1 | -0.0501485 |
| MT2A | metallothionein 2A | -0.0490008 |
| IER3 | immediate early response 3 | -0.0489498 |
| GOLGA4 | golgin A4 | -0.0488825 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0476598 |
| RBM39 | RNA binding motif protein 39 | -0.0465203 |
| RPLP2 | ribosomal protein, large, P2 | -0.0457494 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0450539 |
| TMEM132D | transmembrane protein 132D | -0.0445167 |
| PTMA | prothymosin, alpha | -0.04431 |
| MYOF | myoferlin | -0.0440817 |
| CDH13 | cadherin 13 | -0.0434655 |
| DST | dystonin | -0.0433453 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0420642 |
| AFF3 | AF4/FMR2 family, member 3 | -0.041645 |
| RPS12 | ribosomal protein S12 | -0.0388938 |
| PCBP2 | poly(rC) binding protein 2 | -0.0388144 |
| POTEF | POTE ankyrin domain family, member F | -0.0386094 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0367408 |
| VMP1 | vacuole membrane protein 1 | -0.0366855 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0363592 |
| ANXA2 | annexin A2 | -0.0360416 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0358702 |
| ARF4 | ADP-ribosylation factor 4 | -0.0358244 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0357336 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0356164 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0351509 |
| PTEN | phosphatase and tensin homolog | -0.0348103 |
| GOLGB1 | golgin B1 | -0.0343349 |
| OGA | O-GlcNAcase | -0.0342937 |
| NABP1 | nucleic acid binding protein 1 | -0.0341166 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0335012 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0333028 |
| RPS24 | ribosomal protein S24 | -0.0327915 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0326275 |
| QKI | QKI, KH domain containing, RNA binding | -0.0319584 |
| RPL26 | ribosomal protein L26 | -0.0318711 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0317892 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.03155 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0314933 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0314727 |
| AFDN | afadin, adherens junction formation factor | -0.0311314 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0304747 |
| SPAG9 | sperm associated antigen 9 | -0.0304402 |
| CALU | calumenin | -0.0301925 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0301532 |
| RPLP1 | ribosomal protein, large, P1 | -0.0300279 |
| RPL37A | ribosomal protein L37a | -0.0297258 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0296323 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0293657 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0293158 |
| MORF4L2 | mortality factor 4 like 2 | -0.0292735 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0292711 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0292563 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0290934 |
| COG5 | component of oligomeric golgi complex 5 | -0.0286309 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0283466 |
| RYBP | RING1 and YY1 binding protein | -0.0281834 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0281796 |
| HMGB2 | high mobility group box 2 | -0.0281471 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0281276 |
| ZNF207 | zinc finger protein 207 | -0.0279399 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0276588 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0276342 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0274764 |
| RPS8 | ribosomal protein S8 | -0.0274723 |
| CDYL | chromodomain protein, Y-like | -0.027453 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0273609 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0272726 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0271573 |
| CANX | calnexin | -0.0268419 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0266664 |
| RPL35A | ribosomal protein L35a | -0.02662 |
