| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Olanzapine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Olanzapine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.0836323 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0688349 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0611125 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0584244 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0536004 |
| FLNA | filamin A, alpha | 0.0418037 |
| PLEC | plectin | 0.0356356 |
| TGM2 | transglutaminase 2 | 0.0344852 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0331887 |
| CEP250 | centrosomal protein 250kDa | 0.0327108 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0302685 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0300266 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0283076 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0273218 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0262302 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0257167 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0254594 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0249887 |
| CPNE1 | copine I | 0.0246069 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0242729 |
| MKI67 | marker of proliferation Ki-67 | 0.0239677 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0232199 |
| ANLN | anillin, actin binding protein | 0.0229233 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0223931 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0222515 |
| AREG | amphiregulin | 0.0220924 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0220146 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0215524 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0210106 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0208816 |
| KIAA0232 | KIAA0232 | 0.0205914 |
| SRCAP | Snf2-related CREBBP activator protein | 0.0203255 |
| SGO2 | shugoshin 2 | 0.0202395 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa | 0.0201578 |
| ACTN4 | actinin, alpha 4 | 0.0198986 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0198265 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0195655 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.0194024 |
| CENPE | centromere protein E, 312kDa | 0.0193389 |
| TTI1 | TELO2 interacting protein 1 | 0.0192284 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0191357 |
| PYGB | phosphorylase, glycogen; brain | 0.0191137 |
| KIAA1549L | KIAA1549-like | 0.019056 |
| UBAC2 | UBA domain containing 2 | 0.0187548 |
| SEPTIN9 | septin 9 | 0.0187236 |
| TXNRD1 | thioredoxin reductase 1 | 0.0186794 |
| CENPF | centromere protein F, 350/400kDa | 0.0186692 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0185931 |
| YAP1 | Yes-associated protein 1 | 0.018343 |
| CCNB1 | cyclin B1 | 0.0183071 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0182707 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0180809 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.018005 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0179256 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0177839 |
| FAM193B | family with sequence similarity 193, member B | 0.0177283 |
| CORO1C | coronin, actin binding protein, 1C | 0.0176481 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0175719 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.017405 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0173301 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0173108 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | 0.0172749 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0172646 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0172377 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0170523 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0170499 |
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.0170239 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0169971 |
| ZBTB44 | zinc finger and BTB domain containing 44 | 0.0169003 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0168258 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0164587 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0162674 |
| CSNK1D | casein kinase 1, delta | 0.0162498 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0161692 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0160025 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.015869 |
| ZC3H18 | zinc finger CCCH-type containing 18 | 0.0157848 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0157018 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0156069 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0155705 |
| RANBP9 | RAN binding protein 9 | 0.015553 |
| EHD4 | EH-domain containing 4 | 0.0155454 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | 0.0155218 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0154919 |
| FMNL2 | formin-like 2 | 0.0152683 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0151867 |
| SPAG5 | sperm associated antigen 5 | 0.0151791 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0151311 |
| TJP1 | tight junction protein 1 | 0.0151234 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | 0.0150309 |
| PER1 | period circadian clock 1 | 0.0150017 |
| TTC21B | tetratricopeptide repeat domain 21B | 0.0149965 |
| TMX1 | thioredoxin-related transmembrane protein 1 | 0.0149345 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0148837 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0148774 |
| CKAP2L | cytoskeleton associated protein 2-like | 0.0148254 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0147848 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0147368 |
| PTGES2 | prostaglandin E synthase 2 | 0.0147095 |
| WDR1 | WD repeat domain 1 | 0.0146714 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.329791 |
| PTMA | prothymosin, alpha | -0.111035 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.110116 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.10451 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0964605 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0953292 |
| TMSB10 | thymosin beta 10 | -0.0923972 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0877853 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0870142 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0790458 |
| VIM | vimentin | -0.0769036 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0740758 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0738105 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0735198 |
| GPC6 | glypican 6 | -0.068386 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.060007 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.059949 |
| EGR1 | early growth response 1 | -0.0592624 |
| GOLGA4 | golgin A4 | -0.0568162 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0568082 |
| RPLP1 | ribosomal protein, large, P1 | -0.0559327 |
| GNAS | GNAS complex locus | -0.0553462 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0543814 |
| RAD51B | RAD51 paralog B | -0.0541611 |
| ZNF609 | zinc finger protein 609 | -0.0525983 |
| SMYD3 | SET and MYND domain containing 3 | -0.0519649 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0519371 |
| IER3 | immediate early response 3 | -0.0502139 |
| PKM | pyruvate kinase, muscle | -0.0501275 |
| SDC4 | syndecan 4 | -0.050058 |
| LDHA | lactate dehydrogenase A | -0.0497604 |
| DST | dystonin | -0.0495006 |
| RAI14 | retinoic acid induced 14 | -0.049436 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0492636 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.049171 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0490753 |
| ZNF638 | zinc finger protein 638 | -0.0488051 |
| ATM | ATM serine/threonine kinase | -0.0486273 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0479988 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0477319 |
| IGF2 | insulin-like growth factor 2 | -0.0476284 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0471542 |
| ATG7 | autophagy related 7 | -0.0462601 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0449995 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0446615 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0443543 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0442611 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0439041 |
| BPTF | bromodomain PHD finger transcription factor | -0.0437701 |
| PRSS23 | protease, serine, 23 | -0.0431456 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0423836 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0421519 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0411421 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0408201 |
| RPL35A | ribosomal protein L35a | -0.0407569 |
| HMGA2 | high mobility group AT-hook 2 | -0.040272 |
| SPAG9 | sperm associated antigen 9 | -0.0399664 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0399002 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0394951 |
| PRKCA | protein kinase C, alpha | -0.0391956 |
| VMP1 | vacuole membrane protein 1 | -0.0390495 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0384497 |
| NCOR1 | nuclear receptor corepressor 1 | -0.038245 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0380238 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0375756 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0375399 |
| NDRG1 | N-myc downstream regulated 1 | -0.0374644 |
| RSF1 | remodeling and spacing factor 1 | -0.037404 |
| NGLY1 | N-glycanase 1 | -0.0372175 |
| SQSTM1 | sequestosome 1 | -0.0370527 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0362055 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0361739 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0361653 |
| OSMR | oncostatin M receptor | -0.0357742 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0355249 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0353013 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0351178 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0350955 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0350351 |
| USP34 | ubiquitin specific peptidase 34 | -0.0349993 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0348286 |
| RPS13 | ribosomal protein S13 | -0.0344699 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0340862 |
| SRPK2 | SRSF protein kinase 2 | -0.0338744 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0336969 |
| LRRC49 | leucine rich repeat containing 49 | -0.0332807 |
| SMAP1 | small ArfGAP 1 | -0.0329819 |
| CANX | calnexin | -0.0328308 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0326864 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0325249 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0325101 |
| GPHN | gephyrin | -0.0323301 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0322334 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0322099 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0319773 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0318398 |
| CD44 | CD44 molecule (Indian blood group) | -0.0317817 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0317384 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0314921 |
| PARD3 | par-3 family cell polarity regulator | -0.0313643 |