| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/6918509 |
| Similar Terms | |
| Downloads & Tools |
197 proteins with high or low expression in Olcegepant relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LIPT1 | lipoyltransferase 1 | 0.73 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 | 0.68 |
| SLC41A1 | solute carrier family 41 (magnesium transporter), member 1 | 0.67 |
| CAPN6 | calpain 6 | 0.63 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.6 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | 0.6 |
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 | 0.6 |
| SPOPL | speckle-type POZ protein-like | 0.51 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.5 |
| SH3D19 | SH3 domain containing 19 | 0.49 |
| PYGM | phosphorylase, glycogen, muscle | 0.48 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) | 0.48 |
| IFT22 | intraflagellar transport 22 | 0.47 |
| ZNF410 | zinc finger protein 410 | 0.46 |
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 | 0.45 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.45 |
| NHEJ1 | nonhomologous end-joining factor 1 | 0.45 |
| PLSCR3 | phospholipid scramblase 3 | 0.45 |
| TNS3 | tensin 3 | 0.44 |
| RAB6D | RAB6D, member RAS oncogene family | 0.44 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.43 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.43 |
| DMD | dystrophin | 0.43 |
| SPPL2A | signal peptide peptidase like 2A | 0.42 |
| TSPAN3 | tetraspanin 3 | 0.42 |
| ASTE1 | asteroid homolog 1 (Drosophila) | 0.41 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.4 |
| CEP70 | centrosomal protein 70kDa | 0.39 |
| ARL4A | ADP-ribosylation factor-like 4A | 0.39 |
| LACC1 | laccase (multicopper oxidoreductase) domain containing 1 | 0.38 |
| KLHL15 | kelch-like family member 15 | 0.37 |
| CCDC28A | coiled-coil domain containing 28A | 0.37 |
| ZNF624 | zinc finger protein 624 | 0.37 |
| JMJD8 | jumonji domain containing 8 | 0.37 |
| ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.36 |
| ZFAND2A | zinc finger, AN1-type domain 2A | 0.36 |
| SHANK3 | SH3 and multiple ankyrin repeat domains 3 | 0.35 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.35 |
| ZNF337 | zinc finger protein 337 | 0.35 |
| DUS4L | dihydrouridine synthase 4-like (S. cerevisiae) | 0.35 |
| BFAR | bifunctional apoptosis regulator | 0.34 |
| TPGS2 | tubulin polyglutamylase complex subunit 2 | 0.34 |
| ZNF354B | zinc finger protein 354B | 0.34 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.34 |
| FNIP1 | folliculin interacting protein 1 | 0.33 |
| SLC35A4 | solute carrier family 35, member A4 | 0.33 |
| ALDH1L2 | aldehyde dehydrogenase 1 family, member L2 | 0.32 |
| TSTD1 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 | 0.31 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | 0.31 |
| HAUS7 | HAUS augmin-like complex, subunit 7 | 0.31 |
| ZNF276 | zinc finger protein 276 | 0.31 |
| ATF3 | activating transcription factor 3 | 0.31 |
| ZNF552 | zinc finger protein 552 | 0.31 |
| GPR161 | G protein-coupled receptor 161 | 0.31 |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 0.31 |
| RP9 | retinitis pigmentosa 9 (autosomal dominant) | 0.31 |
| BAIAP2 | BAI1-associated protein 2 | 0.31 |
| SNX21 | sorting nexin family member 21 | 0.31 |
| DEPDC7 | DEP domain containing 7 | 0.31 |
| TMTC4 | transmembrane and tetratricopeptide repeat containing 4 | 0.3 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 0.3 |
| ZFPM1 | zinc finger protein, FOG family member 1 | 0.3 |
| RAD52 | RAD52 homolog (S. cerevisiae) | 0.3 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.3 |
| SNX33 | sorting nexin 33 | 0.3 |
| PRODH | proline dehydrogenase (oxidase) 1 | 0.3 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.29 |
| FAM53C | family with sequence similarity 53, member C | 0.29 |
| FBXL15 | F-box and leucine-rich repeat protein 15 | 0.29 |
| FRMD6 | FERM domain containing 6 | 0.29 |
| IL17RB | interleukin 17 receptor B | 0.29 |
| USP42 | ubiquitin specific peptidase 42 | 0.29 |
| SPIN2B | spindlin family, member 2B | 0.29 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.29 |
| RUNX2 | runt-related transcription factor 2 | 0.28 |
| COPZ1 | coatomer protein complex, subunit zeta 1 | 0.28 |
| HEMK1 | HemK methyltransferase family member 1 | 0.28 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.28 |
| RBAK | RB-associated KRAB zinc finger | 0.28 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.28 |
| ZC3H14 | zinc finger CCCH-type containing 14 | 0.28 |
| MFSD5 | major facilitator superfamily domain containing 5 | 0.27 |
| YIPF4 | Yip1 domain family, member 4 | 0.27 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.27 |
| ZNF106 | zinc finger protein 106 | 0.27 |
| E2F1 | E2F transcription factor 1 | 0.27 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.27 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.27 |
| KCTD21 | potassium channel tetramerization domain containing 21 | 0.27 |
| USP27X | ubiquitin specific peptidase 27, X-linked | 0.26 |
| SELENOF | selenoprotein F | 0.26 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.26 |
| SUPT7L | suppressor of Ty 7 (S. cerevisiae)-like | 0.26 |
| S100A5 | S100 calcium binding protein A5 | 0.26 |
| TMEM106C | transmembrane protein 106C | 0.26 |
| CCDC14 | coiled-coil domain containing 14 | 0.26 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.26 |
| CDX2 | caudal type homeobox 2 | 0.25 |
| ANKRD36 | ankyrin repeat domain 36 | 0.25 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMOD1 | leiomodin 1 (smooth muscle) | -2.77 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -1.3 |
| PIP | prolactin-induced protein | -1.09 |
| BLOC1S3 | biogenesis of lysosomal organelles complex-1, subunit 3 | -0.88 |
| PALB2 | partner and localizer of BRCA2 | -0.7 |
| ITGA1 | integrin, alpha 1 | -0.68 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.66 |
| SLC6A17 | solute carrier family 6 (neutral amino acid transporter), member 17 | -0.61 |
| SAT2 | spermidine/spermine N1-acetyltransferase family member 2 | -0.6 |
| STMN1 | stathmin 1 | -0.58 |
| TRAK1 | trafficking protein, kinesin binding 1 | -0.55 |
| NCKAP5L | NCK-associated protein 5-like | -0.54 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.52 |
| STMN2 | stathmin 2 | -0.5 |
| MYO15B | myosin XVB | -0.5 |
| FAM174A | family with sequence similarity 174, member A | -0.47 |
| PPP1R2B | PPP1R2 family member B | -0.47 |
| TSPAN33 | tetraspanin 33 | -0.47 |
| TMEM222 | transmembrane protein 222 | -0.46 |
| ZYX | zyxin | -0.44 |
| KBTBD8 | kelch repeat and BTB (POZ) domain containing 8 | -0.42 |
| C11ORF95 | chromosome 11 open reading frame 95 | -0.42 |
| AOC1 | amine oxidase, copper containing 1 | -0.41 |
| MTRES1 | mitochondrial transcription rescue factor 1 | -0.41 |
| DERPC | DERPC proline and glycine rich nuclear protein | -0.41 |
| IER2 | immediate early response 2 | -0.4 |
| PRDM4 | PR domain containing 4 | -0.4 |
| B2M | beta-2-microglobulin | -0.4 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 | -0.39 |
| PRMT2IP | PRMT2 interacting protein | -0.39 |
| TMOD1 | tropomodulin 1 | -0.39 |
| WTAP | Wilms tumor 1 associated protein | -0.39 |
| MARVELD3 | MARVEL domain containing 3 | -0.37 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | -0.37 |
| CCDC90B | coiled-coil domain containing 90B | -0.37 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | -0.37 |
| CALU | calumenin | -0.37 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | -0.36 |
| MEGF6 | multiple EGF-like-domains 6 | -0.36 |
| PKM | pyruvate kinase, muscle | -0.35 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.35 |
| RNF126 | ring finger protein 126 | -0.35 |
| TSSC4 | tumor suppressing subtransferable candidate 4 | -0.34 |
| DCDC1 | doublecortin domain containing 1 | -0.34 |
| ZNF729 | zinc finger protein 729 | -0.34 |
| HMBOX1 | homeobox containing 1 | -0.34 |
| ZNF503 | zinc finger protein 503 | -0.33 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -0.33 |
| TRIAP1 | TP53 regulated inhibitor of apoptosis 1 | -0.33 |
| GLCCI1 | glucocorticoid induced 1 | -0.33 |
| SLC35A5 | solute carrier family 35, member A5 | -0.33 |
| ZNF791 | zinc finger protein 791 | -0.33 |
| CMC2 | C-x(9)-C motif containing 2 | -0.32 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | -0.32 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | -0.32 |
| SUCO | SUN domain containing ossification factor | -0.32 |
| CUEDC2 | CUE domain containing 2 | -0.32 |
| HMGB2 | high mobility group box 2 | -0.31 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.31 |
| CLASP1 | cytoplasmic linker associated protein 1 | -0.31 |
| BAG3 | BCL2-associated athanogene 3 | -0.31 |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) | -0.31 |
| STK19 | serine/threonine kinase 19 | -0.31 |
| TRAM2 | translocation associated membrane protein 2 | -0.31 |
| MED4 | mediator complex subunit 4 | -0.3 |
| ATXN1L | ataxin 1-like | -0.3 |
| MCRIP1 | MAPK regulated corepressor interacting protein 1 | -0.29 |
| SNAPIN | SNAP-associated protein | -0.29 |
| CCDC88A | coiled-coil domain containing 88A | -0.29 |
| CETN1 | centrin, EF-hand protein, 1 | -0.29 |
| SH3BP5L | SH3-binding domain protein 5-like | -0.29 |
| TPM4 | tropomyosin 4 | -0.29 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.28 |
| GAS2L1 | growth arrest-specific 2 like 1 | -0.28 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.28 |
| ENY2 | enhancer of yellow 2 homolog (Drosophila) | -0.28 |
| RILPL1 | Rab interacting lysosomal protein-like 1 | -0.28 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.28 |
| DDA1 | DET1 and DDB1 associated 1 | -0.28 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.28 |
| PSEN1 | presenilin 1 | -0.28 |
| ZMAT5 | zinc finger, matrin-type 5 | -0.28 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.27 |
| H2AZ1 | H2A.Z variant histone 1 | -0.27 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) | -0.27 |
| BORCS6 | BLOC-1 related complex subunit 6 | -0.27 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) | -0.27 |
| MYZAP | myocardial zonula adherens protein | -0.27 |
| NUCB2 | nucleobindin 2 | -0.27 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | -0.27 |
| DNPEP | aspartyl aminopeptidase | -0.27 |
| PDLIM1 | PDZ and LIM domain 1 | -0.27 |
| AP4S1 | adaptor-related protein complex 4, sigma 1 subunit | -0.27 |
| S100A4 | S100 calcium binding protein A4 | -0.27 |
| AMZ2 | archaelysin family metallopeptidase 2 | -0.26 |
| BHLHA15 | basic helix-loop-helix family, member a15 | -0.26 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | -0.26 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.26 |
