Oleic acid_C-33 A Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Oleic acid perturbation in C-33 A cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Oleic acid_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
SLIT2 slit homolog 2 (Drosophila) 0.178558
ZNF608 zinc finger protein 608 0.132121
ADGRG6 adhesion G protein-coupled receptor G6 0.0976228
EEF2 eukaryotic translation elongation factor 2 0.0935284
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.0874272
JMJD1C jumonji domain containing 1C 0.0870918
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 0.083486
VCL vinculin 0.0833161
TENM3 teneurin transmembrane protein 3 0.0804413
DST dystonin 0.079411
COL5A2 collagen, type V, alpha 2 0.0746813
ERBB4 erb-b2 receptor tyrosine kinase 4 0.0743218
NEBL nebulette 0.0695596
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0571506
ATP11A ATPase, class VI, type 11A 0.0552297
SIK3 SIK family kinase 3 0.053032
USP9X ubiquitin specific peptidase 9, X-linked 0.0526783
ZSWIM6 zinc finger, SWIM-type containing 6 0.0510369
TOX thymocyte selection-associated high mobility group box 0.0507615
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0455573
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0453159
NBEAL1 neurobeachin-like 1 0.0446312
SIK2 salt-inducible kinase 2 0.0429429
MLIP muscular LMNA-interacting protein 0.0426359
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0422119
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0407295
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0405639
SOX5 SRY (sex determining region Y)-box 5 0.0379934
VMP1 vacuole membrane protein 1 0.0369718
PCNX4 pecanex 4 0.0358303
PDE4D phosphodiesterase 4D, cAMP-specific 0.035675
HOMER1 homer scaffolding protein 1 0.0354365
EXT1 exostosin glycosyltransferase 1 0.0348898
TAS2R14 taste receptor, type 2, member 14 0.0346044
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0336469
BNC2 basonuclin 2 0.0330931
MCTP1 multiple C2 domains, transmembrane 1 0.0325723
TET2 tet methylcytosine dioxygenase 2 0.0320482
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.0316576
JARID2 jumonji, AT rich interactive domain 2 0.0311321
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0306742
WLS wntless Wnt ligand secretion mediator 0.0304599
ARFGEF3 ARFGEF family member 3 0.0303976
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0298011
ATP9A ATPase, class II, type 9A 0.0295047
STAT1 signal transducer and activator of transcription 1, 91kDa 0.029316
NGLY1 N-glycanase 1 0.0290937
NFIA nuclear factor I/A 0.0289439
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0284483
HHIP hedgehog interacting protein 0.0281604
ZFAND3 zinc finger, AN1-type domain 3 0.0279487
NBEA neurobeachin 0.0272757
DSCAM Down syndrome cell adhesion molecule 0.0270462
USP34 ubiquitin specific peptidase 34 0.0269828
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0267922
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 0.0267573
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.0265651
NFIB nuclear factor I/B 0.0256642
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0253063
FBXL17 F-box and leucine-rich repeat protein 17 0.02527
ANO6 anoctamin 6 0.0250673
CADM2 cell adhesion molecule 2 0.0250515
SMAD6 SMAD family member 6 0.0247385
CELF2 CUGBP, Elav-like family member 2 0.0243213
VEGFC vascular endothelial growth factor C 0.023896
WNK1 WNK lysine deficient protein kinase 1 0.0238624
EFNA5 ephrin-A5 0.023793
USP47 ubiquitin specific peptidase 47 0.0233162
ELF2 E74-like factor 2 (ets domain transcription factor) 0.0231713
RCOR1 REST corepressor 1 0.0230116
SERTAD2 SERTA domain containing 2 0.0228082
MYO1E myosin IE 0.0227011
LOC112694756 uncharaterized LOC112694756 0.022413
TBL1X transducin (beta)-like 1X-linked 0.0221586
RSU1 Ras suppressor protein 1 0.0220996
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0220458
YAP1 Yes-associated protein 1 0.0217487
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0213555
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.021243
CLTC clathrin, heavy chain (Hc) 0.0212178
ASCC3 activating signal cointegrator 1 complex subunit 3 0.0212177
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.0209551
PHF3 PHD finger protein 3 0.0207091
ATXN7 ataxin 7 0.0206423
ATF6 activating transcription factor 6 0.0201804
NALF1 NALCN channel auxiliary factor 1 0.0200921
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.0200724
MBD5 methyl-CpG binding domain protein 5 0.0200394
EPC2 enhancer of polycomb homolog 2 (Drosophila) 0.0200091
BCAS3 breast carcinoma amplified sequence 3 0.020002
FOSL2 FOS-like antigen 2 0.0198118
ATG10 autophagy related 10 0.0197634
ARB2A ARB2 cotranscriptional regulator A 0.0196552
AHI1 Abelson helper integration site 1 0.0196108
CABIN1 calcineurin binding protein 1 0.0196088
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0195428
GYS1 glycogen synthase 1 (muscle) 0.0195301
MCL1 myeloid cell leukemia 1 0.019472
RPL3 ribosomal protein L3 0.0194497
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0193063

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.1196
PTMA prothymosin, alpha -0.117106
CTNNA3 catenin (cadherin-associated protein), alpha 3 -0.105297
TMSB10 thymosin beta 10 -0.0950806
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0844269
RPS21 ribosomal protein S21 -0.0794742
ACTG1 actin gamma 1 -0.0703927
RPL11 ribosomal protein L11 -0.0701583
RPLP2 ribosomal protein, large, P2 -0.0649263
RPS6 ribosomal protein S6 -0.0630815
IFI6 interferon, alpha-inducible protein 6 -0.0620387
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0602442
NPAS3 neuronal PAS domain protein 3 -0.0586284
RPL37A ribosomal protein L37a -0.0577195
RPLP1 ribosomal protein, large, P1 -0.0558056
RPL23 ribosomal protein L23 -0.0544148
KPNB1 karyopherin (importin) beta 1 -0.0532251
RPS3 ribosomal protein S3 -0.0520608
CTNNA2 catenin (cadherin-associated protein), alpha 2 -0.0505317
RPS29 ribosomal protein S29 -0.0479301
RPS24 ribosomal protein S24 -0.0475633
RPS12 ribosomal protein S12 -0.0471158
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0470022
RPL12 ribosomal protein L12 -0.0460127
RPS8 ribosomal protein S8 -0.0450439
RPL34 ribosomal protein L34 -0.0448109
RBM25 RNA binding motif protein 25 -0.0447386
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0444047
PFN1 profilin 1 -0.0437521
HMGA1 high mobility group AT-hook 1 -0.0433587
SERBP1 SERPINE1 mRNA binding protein 1 -0.0433001
RPS19 ribosomal protein S19 -0.0425196
DEK DEK proto-oncogene -0.0410246
RPL35A ribosomal protein L35a -0.0406925
HMGB1 high mobility group box 1 -0.0404232
CENPF centromere protein F, 350/400kDa -0.0403132
RPL27A ribosomal protein L27a -0.0384489
RPS25 ribosomal protein S25 -0.0381747
RPS11 ribosomal protein S11 -0.0380907
LDHA lactate dehydrogenase A -0.037711
RPL32 ribosomal protein L32 -0.0376976
RPL26 ribosomal protein L26 -0.0372963
SOX4 SRY (sex determining region Y)-box 4 -0.0370927
RPL31 ribosomal protein L31 -0.036838
RPL28 ribosomal protein L28 -0.0368099
EIF4A1 eukaryotic translation initiation factor 4A1 -0.0352838
ACACA acetyl-CoA carboxylase alpha -0.0351818
EIF5B eukaryotic translation initiation factor 5B -0.0348805
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.034801
NAP1L1 nucleosome assembly protein 1-like 1 -0.0346295
FTL ferritin, light polypeptide -0.0338058
RPS15 ribosomal protein S15 -0.0328283
RPL19 ribosomal protein L19 -0.032485
TPT1 tumor protein, translationally-controlled 1 -0.0321636
RPS5 ribosomal protein S5 -0.0317294
RPL8 ribosomal protein L8 -0.0316787
RPL36 ribosomal protein L36 -0.0310709
RPS28 ribosomal protein S28 -0.0306229
RACK1 receptor for activated C kinase 1 -0.0300328
TUBB tubulin, beta class I -0.0298434
RPS27A ribosomal protein S27a -0.0292333
ZMYND8 zinc finger, MYND-type containing 8 -0.0292064
RSL1D1 ribosomal L1 domain containing 1 -0.0291738
RPS13 ribosomal protein S13 -0.0287867
VDAC1 voltage-dependent anion channel 1 -0.0286231
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0285926
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0283248
RPS23 ribosomal protein S23 -0.0282642
RPL36A ribosomal protein L36a -0.0282142
SOX2 SRY (sex determining region Y)-box 2 -0.0279988
MYL12B myosin, light chain 12B, regulatory -0.0277698
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.027434
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0274141
WSB1 WD repeat and SOCS box containing 1 -0.0273571
ISG15 ISG15 ubiquitin-like modifier -0.0270362
NOP56 NOP56 ribonucleoprotein -0.0269413
RPL30 ribosomal protein L30 -0.0268006
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -0.0265616
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.026476
RPL38 ribosomal protein L38 -0.0263088
RPL35 ribosomal protein L35 -0.0260744
RPS10 ribosomal protein S10 -0.0259078
RPL18 ribosomal protein L18 -0.0256072
RPS16 ribosomal protein S16 -0.025576
CBX3 chromobox homolog 3 -0.0255405
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0253956
NCOR1 nuclear receptor corepressor 1 -0.0252991
RPL9 ribosomal protein L9 -0.0249543
S100A9 S100 calcium binding protein A9 -0.0248937
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0246359
CCT4 chaperonin containing TCP1, subunit 4 (delta) -0.0238886
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.0237217
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0236617
RPL7A ribosomal protein L7a -0.0235946
FAM162A family with sequence similarity 162, member A -0.0235352
PNISR PNN-interacting serine/arginine-rich protein -0.0232906
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -0.023198
PA2G4 proliferation-associated 2G4, 38kDa -0.0231959
SHROOM3 shroom family member 3 -0.0227768
MT2A metallothionein 2A -0.0225442