Oleic acid_COLO 205 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Oleic acid perturbation in COLO 205 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Oleic acid_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
LMO7 LIM domain 7 0.270008
EXT1 exostosin glycosyltransferase 1 0.131961
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.129342
EPSTI1 epithelial stromal interaction 1 (breast) 0.12527
SMAD3 SMAD family member 3 0.122688
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.121153
RNF213 ring finger protein 213 0.109298
SPTBN1 spectrin, beta, non-erythrocytic 1 0.109053
ANXA2 annexin A2 0.101252
INTS6 integrator complex subunit 6 0.0975673
STS steroid sulfatase (microsomal), isozyme S 0.0893513
AKAP13 A kinase (PRKA) anchor protein 13 0.0889669
GMDS GDP-mannose 4,6-dehydratase 0.0872711
MYO1E myosin IE 0.087037
ARHGAP26 Rho GTPase activating protein 26 0.0819032
MX1 MX dynamin-like GTPase 1 0.0818856
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0816744
GCLC glutamate-cysteine ligase, catalytic subunit 0.0757006
ERBIN erbb2 interacting protein 0.0751074
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0736869
SP100 SP100 nuclear antigen 0.071191
ZSWIM6 zinc finger, SWIM-type containing 6 0.069831
FNDC3B fibronectin type III domain containing 3B 0.0664715
PRKCA protein kinase C, alpha 0.0651617
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0647209
LPP LIM domain containing preferred translocation partner in lipoma 0.0631875
EFNB2 ephrin-B2 0.0630962
TMC5 transmembrane channel-like 5 0.0616165
ASPH aspartate beta-hydroxylase 0.0612782
VCL vinculin 0.0583461
RIGI RNA sensor RIG-I 0.0582006
MCU mitochondrial calcium uniporter 0.0572804
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0563635
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0562098
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0.0562023
MSI2 musashi RNA-binding protein 2 0.0549168
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.0548215
CATSPERB catsper channel auxiliary subunit beta 0.0532756
FTH1 ferritin, heavy polypeptide 1 0.0530746
AREG amphiregulin 0.0526981
DSCAM Down syndrome cell adhesion molecule 0.0524624
TJP1 tight junction protein 1 0.0523217
ERN1 endoplasmic reticulum to nucleus signaling 1 0.0518255
MX2 MX dynamin-like GTPase 2 0.0510303
C6ORF132 chromosome 6 open reading frame 132 0.0508418
MACC1 metastasis associated in colon cancer 1 0.0497608
RAB7A RAB7A, member RAS oncogene family 0.0495144
BAIAP2L1 BAI1-associated protein 2-like 1 0.0480437
PHF3 PHD finger protein 3 0.0466907
MAP7 microtubule-associated protein 7 0.0457507
ETV6 ets variant 6 0.0455911
RABGAP1L RAB GTPase activating protein 1-like 0.0454677
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0452725
SEPTIN9 septin 9 0.0448386
ITGA6 integrin, alpha 6 0.0446736
PLSCR2 phospholipid scramblase 2 0.0446632
TSC22D1 TSC22 domain family, member 1 0.0443183
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0441893
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0436812
TSHZ2 teashirt zinc finger homeobox 2 0.0429154
KYNU kynureninase 0.0424599
PLSCR1 phospholipid scramblase 1 0.0423077
SIPA1L2 signal-induced proliferation-associated 1 like 2 0.0421942
FAT1 FAT atypical cadherin 1 0.0418645
HKDC1 hexokinase domain containing 1 0.0410768
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0404928
DST dystonin 0.0401923
SPATA13 spermatogenesis associated 13 0.0401227
SERINC5 serine incorporator 5 0.0400193
DIAPH1 diaphanous-related formin 1 0.0399832
MYO5B myosin VB 0.0397156
RBM47 RNA binding motif protein 47 0.0394577
ELOF1 elongation factor 1 homolog (S. cerevisiae) 0.0389117
IGFBP3 insulin-like growth factor binding protein 3 0.0385959
TM4SF19 transmembrane 4 L six family member 19 0.0375747
TRIO trio Rho guanine nucleotide exchange factor 0.0373662
CEMIP cell migration inducing protein, hyaluronan binding 0.0371864
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.0364504
SSH2 slingshot protein phosphatase 2 0.0363449
ATP11A ATPase, class VI, type 11A 0.0359971
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 0.0359516
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.0357282
VMP1 vacuole membrane protein 1 0.0356916
PDLIM5 PDZ and LIM domain 5 0.0351637
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.035044
MYH14 myosin, heavy chain 14, non-muscle 0.0349902
SHB Src homology 2 domain containing adaptor protein B 0.0349157
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0347053
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0344665
FNIP2 folliculin interacting protein 2 0.0344362
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.034328
SQSTM1 sequestosome 1 0.0343277
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.0336606
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.0335084
MCL1 myeloid cell leukemia 1 0.0334209
NCEH1 neutral cholesterol ester hydrolase 1 0.0330943
KIF16B kinesin family member 16B 0.0329366
RSAD2 radical S-adenosyl methionine domain containing 2 0.0328557
ATXN1 ataxin 1 0.0325714
MAML2 mastermind-like 2 (Drosophila) 0.032542

decreased expression

Symbol Name Standardized Value
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.169157
TPT1 tumor protein, translationally-controlled 1 -0.10228
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0950279
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.079531
B2M beta-2-microglobulin -0.0510652
PDIA3 protein disulfide isomerase family A, member 3 -0.0477457
PTMA prothymosin, alpha -0.0457286
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0427468
RPS6 ribosomal protein S6 -0.0423196
HLA-B major histocompatibility complex, class I, B -0.0407289
RPL35A ribosomal protein L35a -0.0403826
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0397769
RNF149 ring finger protein 149 -0.0392818
TMSB10 thymosin beta 10 -0.0373449
RPLP1 ribosomal protein, large, P1 -0.0358895
EIF1 eukaryotic translation initiation factor 1 -0.0341859
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0339423
TXNIP thioredoxin interacting protein -0.0334273
RPL23 ribosomal protein L23 -0.0322903
CALR calreticulin -0.0314054
ACBD3 acyl-CoA binding domain containing 3 -0.030959
GOLGA4 golgin A4 -0.0302394
RHOBTB3 Rho-related BTB domain containing 3 -0.0298645
FTL ferritin, light polypeptide -0.0297483
RNF43 ring finger protein 43 -0.0295059
NDRG1 N-myc downstream regulated 1 -0.0290959
DIAPH3 diaphanous-related formin 3 -0.0284074
GNAS GNAS complex locus -0.0283355
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0282539
WSB1 WD repeat and SOCS box containing 1 -0.0281693
MKI67 marker of proliferation Ki-67 -0.0279806
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0278091
RPL34 ribosomal protein L34 -0.0277499
RPL12 ribosomal protein L12 -0.0275159
RPS19 ribosomal protein S19 -0.0265586
CANX calnexin -0.0259231
MT2A metallothionein 2A -0.0257163
RBM39 RNA binding motif protein 39 -0.0256094
NAMPT nicotinamide phosphoribosyltransferase -0.0255381
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0250785
RPS8 ribosomal protein S8 -0.0247515
RPS24 ribosomal protein S24 -0.0246353
RPS3 ribosomal protein S3 -0.0243069
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.0239709
RPL19 ribosomal protein L19 -0.0239546
SEC24D SEC24 family member D -0.0238314
AGR2 anterior gradient 2 -0.023754
USP3 ubiquitin specific peptidase 3 -0.0234803
CALU calumenin -0.0234018
RPL31 ribosomal protein L31 -0.0229428
RPL26 ribosomal protein L26 -0.0227503
ZMYM2 zinc finger, MYM-type 2 -0.0227422
NUCB2 nucleobindin 2 -0.0225071
AKAP9 A kinase (PRKA) anchor protein 9 -0.0220432
PTEN phosphatase and tensin homolog -0.0219679
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -0.0219175
TTC3 tetratricopeptide repeat domain 3 -0.0217948
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0215542
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0212805
TMEM263 transmembrane protein 263 -0.0212737
SMC4 structural maintenance of chromosomes 4 -0.0212426
RPL37A ribosomal protein L37a -0.0210492
MORF4L2 mortality factor 4 like 2 -0.0205905
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0202897
CENPF centromere protein F, 350/400kDa -0.0202471
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.0202055
LMAN1 lectin, mannose-binding, 1 -0.0201334
MT1X metallothionein 1X -0.0200508
RPS12 ribosomal protein S12 -0.0198869
RPS29 ribosomal protein S29 -0.0197972
MBNL2 muscleblind-like splicing regulator 2 -0.0197545
UBE2D3 ubiquitin-conjugating enzyme E2D 3 -0.0196686
RPLP2 ribosomal protein, large, P2 -0.0196188
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0191671
SBF2 SET binding factor 2 -0.0190762
RPL37 ribosomal protein L37 -0.018927
UFM1 ubiquitin-fold modifier 1 -0.0188243
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0185761
RPL28 ribosomal protein L28 -0.0181505
UQCRB ubiquinol-cytochrome c reductase binding protein -0.0180906
RPS23 ribosomal protein S23 -0.018085
RPL38 ribosomal protein L38 -0.0180546
RPS27 ribosomal protein S27 -0.0177094
RAB1A RAB1A, member RAS oncogene family -0.0176981
COG6 component of oligomeric golgi complex 6 -0.01768
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.0176118
RPS21 ribosomal protein S21 -0.0174905
RPL11 ribosomal protein L11 -0.017429
NRIP1 nuclear receptor interacting protein 1 -0.0172693
KDM3A lysine (K)-specific demethylase 3A -0.0172131
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -0.0171052
TMEM87A transmembrane protein 87A -0.0169791
RPS13 ribosomal protein S13 -0.0169085
MTDH metadherin -0.0168095
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.0167138
OGA O-GlcNAcase -0.0165575
MATR3 matrin 3 -0.01655
SREBF2 sterol regulatory element binding transcription factor 2 -0.0164016
FANCI Fanconi anemia, complementation group I -0.016398
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -0.0161299