Oleic acid_HEC-1-A Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Oleic acid perturbation in HEC-1-A cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Oleic acid_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.154354
MYH9 myosin, heavy chain 9, non-muscle 0.147963
EEF2 eukaryotic translation elongation factor 2 0.121467
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.107066
FLNA filamin A, alpha 0.0944763
FNDC3B fibronectin type III domain containing 3B 0.0929882
NDRG1 N-myc downstream regulated 1 0.0863429
SIPA1L3 signal-induced proliferation-associated 1 like 3 0.0835741
ANXA2 annexin A2 0.0823717
POTEF POTE ankyrin domain family, member F 0.0823512
FTH1 ferritin, heavy polypeptide 1 0.080323
PLEC plectin 0.0782863
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0758614
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0744824
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0729329
IGFBP3 insulin-like growth factor binding protein 3 0.0712523
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0688745
SMAD3 SMAD family member 3 0.067321
HELZ helicase with zinc finger 0.065973
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0649607
ASPH aspartate beta-hydroxylase 0.0615549
PSD3 pleckstrin and Sec7 domain containing 3 0.0605149
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0598839
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0594505
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.0593007
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.0584965
P4HB prolyl 4-hydroxylase, beta polypeptide 0.057935
RUNX1 runt-related transcription factor 1 0.0575404
LOC112694756 uncharaterized LOC112694756 0.0573581
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.0571997
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0565635
PKM pyruvate kinase, muscle 0.0562991
PRELID2 PRELI domain containing 2 0.0562511
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.055902
WWC1 WW and C2 domain containing 1 0.0555897
PAX8 paired box 8 0.0542208
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0539714
ECT2 epithelial cell transforming 2 0.0539305
KRT7 keratin 7, type II 0.0539252
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0535717
APLP2 amyloid beta (A4) precursor-like protein 2 0.0530296
NCEH1 neutral cholesterol ester hydrolase 1 0.0527298
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0525464
SVIL supervillin 0.0515018
APP amyloid beta (A4) precursor protein 0.0510912
SEPTIN9 septin 9 0.0507592
SPAG9 sperm associated antigen 9 0.050232
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0497705
ALCAM activated leukocyte cell adhesion molecule 0.0491241
TJP1 tight junction protein 1 0.0490592
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0481149
SNX9 sorting nexin 9 0.0474449
TRIO trio Rho guanine nucleotide exchange factor 0.0471261
FLNB filamin B, beta 0.0463055
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0459063
EZR ezrin 0.0455778
H1-0 H1.0 linker histone 0.0453196
ZSWIM6 zinc finger, SWIM-type containing 6 0.0452786
PCBP2 poly(rC) binding protein 2 0.0446637
ENO1 enolase 1, (alpha) 0.0436308
DIAPH1 diaphanous-related formin 1 0.043408
PCSK5 proprotein convertase subtilisin/kexin type 5 0.0426151
MYO1E myosin IE 0.0425339
OSBPL10 oxysterol binding protein-like 10 0.0418478
ITGB8 integrin, beta 8 0.0417939
IQGAP1 IQ motif containing GTPase activating protein 1 0.0411305
TPM4 tropomyosin 4 0.040896
ERRFI1 ERBB receptor feedback inhibitor 1 0.0407469
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0398395
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0397563
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0392423
AKAP9 A kinase (PRKA) anchor protein 9 0.0386481
SRRM2 serine/arginine repetitive matrix 2 0.0385935
ADAM9 ADAM metallopeptidase domain 9 0.0385752
SHB Src homology 2 domain containing adaptor protein B 0.038264
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0381249
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.0376356
ANKRD33B ankyrin repeat domain 33B 0.0376166
ATXN1 ataxin 1 0.0375308
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0370844
RPS2 ribosomal protein S2 0.0369223
MPRIP myosin phosphatase Rho interacting protein 0.0368441
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0365945
SET SET nuclear proto-oncogene 0.0364328
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0361803
LPP LIM domain containing preferred translocation partner in lipoma 0.0361628
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.0360317
DSPP dentin sialophosphoprotein 0.0359092
DSG2 desmoglein 2 0.0359027
RYBP RING1 and YY1 binding protein 0.0358312
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0358252
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.0357768
FXR1 fragile X mental retardation, autosomal homolog 1 0.035602
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0355502
ANXA1 annexin A1 0.0354777
MACF1 microtubule-actin crosslinking factor 1 0.0354184
TPM3 tropomyosin 3 0.0352719
SQSTM1 sequestosome 1 0.0352529
YBX1 Y box binding protein 1 0.0348498
MACC1 metastasis associated in colon cancer 1 0.0346941

decreased expression

Symbol Name Standardized Value
TMSB10 thymosin beta 10 -0.144196
TPT1 tumor protein, translationally-controlled 1 -0.132278
PTMA prothymosin, alpha -0.0820025
MT2A metallothionein 2A -0.0814418
RPL35A ribosomal protein L35a -0.0809052
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0774405
RHEX regulator of hemoglobinization and erythroid cell expansion -0.0608758
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.0604688
RPLP2 ribosomal protein, large, P2 -0.0579341
RPS19 ribosomal protein S19 -0.0571942
RPL31 ribosomal protein L31 -0.0567381
RPL32 ribosomal protein L32 -0.0552687
RPS29 ribosomal protein S29 -0.0545274
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -0.0533174
RPL37A ribosomal protein L37a -0.0523486
RPLP1 ribosomal protein, large, P1 -0.0414048
RPS27A ribosomal protein S27a -0.0404584
RPL38 ribosomal protein L38 -0.0396647
RPL19 ribosomal protein L19 -0.0383227
RPS24 ribosomal protein S24 -0.0369439
RPS3 ribosomal protein S3 -0.0340638
BICD1 bicaudal D homolog 1 (Drosophila) -0.0323165
RPL9 ribosomal protein L9 -0.0321409
RPS13 ribosomal protein S13 -0.0320894
RPS25 ribosomal protein S25 -0.0319469
RPL34 ribosomal protein L34 -0.0315145
RPS21 ribosomal protein S21 -0.030918
RPL26 ribosomal protein L26 -0.0308354
RPS23 ribosomal protein S23 -0.0306318
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0301782
RPL36 ribosomal protein L36 -0.0299508
TM9SF3 transmembrane 9 superfamily member 3 -0.0284388
EIF5B eukaryotic translation initiation factor 5B -0.0282545
DSCAML1 Down syndrome cell adhesion molecule like 1 -0.0282344
UQCRB ubiquinol-cytochrome c reductase binding protein -0.0279065
RPS15 ribosomal protein S15 -0.0274414
MYL12B myosin, light chain 12B, regulatory -0.0273576
RPS11 ribosomal protein S11 -0.0271022
RPL37 ribosomal protein L37 -0.0269647
DLC1 DLC1 Rho GTPase activating protein -0.0264387
RPS8 ribosomal protein S8 -0.0262849
RBM25 RNA binding motif protein 25 -0.0258568
WSB1 WD repeat and SOCS box containing 1 -0.0256409
GCC2 GRIP and coiled-coil domain containing 2 -0.0256402
RPL36A ribosomal protein L36a -0.0243659
EIF1 eukaryotic translation initiation factor 1 -0.0240462
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0233093
RPS10 ribosomal protein S10 -0.0231673
RPL7A ribosomal protein L7a -0.0228366
RPL23 ribosomal protein L23 -0.0227586
ZBTB20 zinc finger and BTB domain containing 20 -0.0221908
RAN RAN, member RAS oncogene family -0.0217531
ANKRD10 ankyrin repeat domain 10 -0.0216439
RPL28 ribosomal protein L28 -0.0214251
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -0.0213375
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -0.0212838
TMSB4X thymosin beta 4, X-linked -0.0211829
VDAC1 voltage-dependent anion channel 1 -0.020993
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0205634
RPS16 ribosomal protein S16 -0.0202948
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -0.0198931
RPS14 ribosomal protein S14 -0.0194019
PCED1B PC-esterase domain containing 1B -0.0193691
GSTP1 glutathione S-transferase pi 1 -0.0192506
ZMYND8 zinc finger, MYND-type containing 8 -0.0190634
RPL30 ribosomal protein L30 -0.0189562
EDF1 endothelial differentiation-related factor 1 -0.0187369
PNISR PNN-interacting serine/arginine-rich protein -0.0186074
ACACA acetyl-CoA carboxylase alpha -0.0185584
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0182706
TUBB4B tubulin, beta 4B class IVb -0.0182415
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -0.0182243
FIGN fidgetin -0.0180358
MT1X metallothionein 1X -0.0180223
RPL35 ribosomal protein L35 -0.0178756
RPL27 ribosomal protein L27 -0.0172433
POU5F1 POU class 5 homeobox 1 -0.0170586
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0169727
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0169117
S100A11 S100 calcium binding protein A11 -0.0167266
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -0.0166374
DEK DEK proto-oncogene -0.0165254
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0164969
LMNA lamin A/C -0.0163208
RPS12 ribosomal protein S12 -0.016243
ZRANB2 zinc finger, RAN-binding domain containing 2 -0.0161658
TUBB tubulin, beta class I -0.0160893
LITAF lipopolysaccharide-induced TNF factor -0.0160638
KHSRP KH-type splicing regulatory protein -0.016019
THOC2 THO complex 2 -0.0159555
MAML2 mastermind-like 2 (Drosophila) -0.0158405
ZBTB7A zinc finger and BTB domain containing 7A -0.0157867
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0156679
NME2 NME/NM23 nucleoside diphosphate kinase 2 -0.0156594
TRIM56 tripartite motif containing 56 -0.0152256
NDFIP1 Nedd4 family interacting protein 1 -0.0151607
RPL36AL ribosomal protein L36a-like -0.0150878
DLG1 discs, large homolog 1 (Drosophila) -0.0150604
SERF2 small EDRK-rich factor 2 -0.0150541
RPL5 ribosomal protein L5 -0.0150345