| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oleic acid perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Oleic acid_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.255868 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.205906 |
| NDRG1 | N-myc downstream regulated 1 | 0.151359 |
| VEGFA | vascular endothelial growth factor A | 0.132588 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.120964 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.109511 |
| FNDC3B | fibronectin type III domain containing 3B | 0.10407 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.100561 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.091832 |
| CADM1 | cell adhesion molecule 1 | 0.0864731 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0833138 |
| CD44 | CD44 molecule (Indian blood group) | 0.0820337 |
| PLEC | plectin | 0.074591 |
| STC1 | stanniocalcin 1 | 0.0676507 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0648272 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0633504 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0596919 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0594532 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0587453 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0559704 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0538454 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0523517 |
| EXT1 | exostosin glycosyltransferase 1 | 0.051348 |
| CDH13 | cadherin 13 | 0.051341 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0497186 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0492544 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0488522 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0468705 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0460884 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0449928 |
| ARRDC3 | arrestin domain containing 3 | 0.0407938 |
| PDE10A | phosphodiesterase 10A | 0.0407861 |
| PTK2 | protein tyrosine kinase 2 | 0.0406584 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0397354 |
| FLNA | filamin A, alpha | 0.0371335 |
| GOLGB1 | golgin B1 | 0.0365866 |
| NAV2 | neuron navigator 2 | 0.0359797 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0357703 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0352972 |
| GOLGA4 | golgin A4 | 0.0352145 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0345244 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0342317 |
| SMAD3 | SMAD family member 3 | 0.0338553 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0338207 |
| MYO10 | myosin X | 0.0337062 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0336335 |
| LOXL2 | lysyl oxidase-like 2 | 0.0326472 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0319142 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0318243 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0308813 |
| HYOU1 | hypoxia up-regulated 1 | 0.0297562 |
| RUNX1 | runt-related transcription factor 1 | 0.0295877 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0293478 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0292507 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0286111 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0279686 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0279294 |
| SPAG9 | sperm associated antigen 9 | 0.0279123 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0270145 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0267692 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0266628 |
| EGFR | epidermal growth factor receptor | 0.0266452 |
| ANO6 | anoctamin 6 | 0.0265709 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0260313 |
| CALR | calreticulin | 0.025832 |
| STC2 | stanniocalcin 2 | 0.0258151 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0256893 |
| COPA | coatomer protein complex, subunit alpha | 0.0254926 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0251936 |
| HDLBP | high density lipoprotein binding protein | 0.0246728 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.024308 |
| NOTCH2 | notch 2 | 0.0242906 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0239157 |
| MLF1 | myeloid leukemia factor 1 | 0.023279 |
| PGM3 | phosphoglucomutase 3 | 0.0231985 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0231835 |
| SUCO | SUN domain containing ossification factor | 0.0231162 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0230045 |
| DSTN | destrin (actin depolymerizing factor) | 0.0229944 |
| RND3 | Rho family GTPase 3 | 0.0229275 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0228316 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0227815 |
| TFG | TRK-fused gene | 0.0226878 |
| LDHA | lactate dehydrogenase A | 0.0225478 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0222833 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0222111 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0219465 |
| SQSTM1 | sequestosome 1 | 0.0219154 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0219114 |
| EFNA5 | ephrin-A5 | 0.0218202 |
| CCNL1 | cyclin L1 | 0.0216258 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0215899 |
| SEPTIN9 | septin 9 | 0.0215683 |
| SRP54 | signal recognition particle 54kDa | 0.0215006 |
| ATP13A3 | ATPase type 13A3 | 0.0214376 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0213043 |
| CMIP | c-Maf inducing protein | 0.0212582 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.021227 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0212187 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0211511 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.275744 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.12273 |
| TMSB10 | thymosin beta 10 | -0.119403 |
| VIM | vimentin | -0.0990169 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.080713 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0509204 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0458642 |
| HLA-B | major histocompatibility complex, class I, B | -0.0451314 |
| CALD1 | caldesmon 1 | -0.0438389 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0414437 |
| CAVIN1 | caveolae associated protein 1 | -0.0412046 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0402245 |
| COL1A2 | collagen, type I, alpha 2 | -0.0387537 |
| RPL37A | ribosomal protein L37a | -0.0381168 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0377445 |
| PTMA | prothymosin, alpha | -0.0370569 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0354571 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0340213 |
| ACTG1 | actin gamma 1 | -0.0337992 |
| RPLP2 | ribosomal protein, large, P2 | -0.0334452 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.033317 |
| IER3 | immediate early response 3 | -0.0316633 |
| SULF1 | sulfatase 1 | -0.0309912 |
| PRELID2 | PRELI domain containing 2 | -0.030899 |
| MT2A | metallothionein 2A | -0.0308951 |
| HMGA2 | high mobility group AT-hook 2 | -0.0308649 |
| RPL35A | ribosomal protein L35a | -0.0305745 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0305179 |
| EGR1 | early growth response 1 | -0.0287425 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0287134 |
| VCL | vinculin | -0.0261664 |
| CNTN5 | contactin 5 | -0.0258553 |
| PRSS23 | protease, serine, 23 | -0.0252123 |
| RPS12 | ribosomal protein S12 | -0.0251948 |
| NREP | neuronal regeneration related protein | -0.0248949 |
| VCAN | versican | -0.0248501 |
| S100A9 | S100 calcium binding protein A9 | -0.0247125 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0240484 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0233475 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0218689 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.02178 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0213164 |
| RPS27A | ribosomal protein S27a | -0.021234 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0207381 |
| RPL23 | ribosomal protein L23 | -0.0206835 |
| RPS29 | ribosomal protein S29 | -0.0205062 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0204248 |
| EBF1 | early B-cell factor 1 | -0.0202353 |
| FRMD4A | FERM domain containing 4A | -0.0199864 |
| FOXP1 | forkhead box P1 | -0.0197638 |
| PALLD | palladin, cytoskeletal associated protein | -0.0197516 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0197085 |
| RPL31 | ribosomal protein L31 | -0.019532 |
| FTL | ferritin, light polypeptide | -0.0193417 |
| TPM1 | tropomyosin 1 (alpha) | -0.0192245 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.0192079 |
| TPM4 | tropomyosin 4 | -0.0191223 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0190437 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0189801 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0187735 |
| RPL28 | ribosomal protein L28 | -0.0187534 |
| RPL38 | ribosomal protein L38 | -0.0183925 |
| LIMA1 | LIM domain and actin binding 1 | -0.0181392 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0180475 |
| S100A10 | S100 calcium binding protein A10 | -0.0178899 |
| RPS10 | ribosomal protein S10 | -0.0178432 |
| RPS8 | ribosomal protein S8 | -0.0174874 |
| RPS3 | ribosomal protein S3 | -0.0174662 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0172648 |
| RPS19 | ribosomal protein S19 | -0.0172146 |
| RASAL2 | RAS protein activator like 2 | -0.016658 |
| PGK1 | phosphoglycerate kinase 1 | -0.0165617 |
| RPL9 | ribosomal protein L9 | -0.0165314 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0165094 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0163772 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0162757 |
| RPL36 | ribosomal protein L36 | -0.0161869 |
| TRIM56 | tripartite motif containing 56 | -0.0161566 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0161065 |
| RPS25 | ribosomal protein S25 | -0.0157021 |
| LAMB3 | laminin, beta 3 | -0.0155688 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.015556 |
| FRMD5 | FERM domain containing 5 | -0.0155008 |
| HMCN1 | hemicentin 1 | -0.0154517 |
| ZNF804A | zinc finger protein 804A | -0.015382 |
| RPL26 | ribosomal protein L26 | -0.0153577 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0152794 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0152712 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0152175 |
| PDLIM5 | PDZ and LIM domain 5 | -0.015174 |
| PRR16 | proline rich 16 | -0.0149618 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.014954 |
| RPS23 | ribosomal protein S23 | -0.0148744 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.014871 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0147049 |
| RPS17 | ribosomal protein S17 | -0.0146591 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.014387 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0141427 |
| PRMT2 | protein arginine methyltransferase 2 | -0.0139784 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0138754 |
