Oleic acid_Hs 766T Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Oleic acid perturbation in Hs 766T cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Oleic acid_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
CD44 CD44 molecule (Indian blood group) 0.127544
LMO7 LIM domain 7 0.105387
TGM2 transglutaminase 2 0.0954003
MTSS1 metastasis suppressor 1 0.0922936
MEF2A myocyte enhancer factor 2A 0.0874734
MYOF myoferlin 0.0796489
ESYT2 extended synaptotagmin-like protein 2 0.0702268
RAI14 retinoic acid induced 14 0.0674068
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0659486
STC1 stanniocalcin 1 0.0657871
H1-0 H1.0 linker histone 0.0637292
PLEC plectin 0.0626349
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.0624718
FLNB filamin B, beta 0.0611246
CLU clusterin 0.0606313
EXT1 exostosin glycosyltransferase 1 0.0540563
FOXO1 forkhead box O1 0.052221
TMSB4X thymosin beta 4, X-linked 0.05181
MYH9 myosin, heavy chain 9, non-muscle 0.0517994
KRT17 keratin 17, type I 0.0490313
TIMP3 TIMP metallopeptidase inhibitor 3 0.0486582
EZR ezrin 0.0478439
HLA-E major histocompatibility complex, class I, E 0.0478098
MBNL1 muscleblind-like splicing regulator 1 0.0475944
EMP1 epithelial membrane protein 1 0.0475849
KTN1 kinectin 1 (kinesin receptor) 0.0472149
LOC112694756 uncharaterized LOC112694756 0.0461391
AHNAK AHNAK nucleoprotein 0.0459914
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0457735
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0446762
NRIP1 nuclear receptor interacting protein 1 0.0445575
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0443897
EEF2 eukaryotic translation elongation factor 2 0.044013
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.0432585
ARHGAP21 Rho GTPase activating protein 21 0.0430952
FTH1 ferritin, heavy polypeptide 1 0.0430009
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.0425637
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0417309
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0409216
RERE arginine-glutamic acid dipeptide (RE) repeats 0.040144
FNDC3B fibronectin type III domain containing 3B 0.0395232
STAU1 staufen double-stranded RNA binding protein 1 0.0388286
ITCH itchy E3 ubiquitin protein ligase 0.038794
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.0386531
BZW1 basic leucine zipper and W2 domains 1 0.0382784
B2M beta-2-microglobulin 0.0379452
MACF1 microtubule-actin crosslinking factor 1 0.0373804
SQLE squalene epoxidase 0.0367004
NAMPT nicotinamide phosphoribosyltransferase 0.0364309
MBNL2 muscleblind-like splicing regulator 2 0.0359713
NDRG1 N-myc downstream regulated 1 0.0359451
ANKRD33B ankyrin repeat domain 33B 0.0355948
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0353587
KMT2E lysine (K)-specific methyltransferase 2E 0.0351908
ANXA2 annexin A2 0.0335804
BHLHE40 basic helix-loop-helix family, member e40 0.0334623
ARRDC3 arrestin domain containing 3 0.033231
AOPEP aminopeptidase O (putative) 0.0330752
CALU calumenin 0.0330456
PDE4D phosphodiesterase 4D, cAMP-specific 0.0330148
PGK1 phosphoglycerate kinase 1 0.0327879
IQGAP1 IQ motif containing GTPase activating protein 1 0.0327292
TRIO trio Rho guanine nucleotide exchange factor 0.0324598
COPB1 coatomer protein complex, subunit beta 1 0.032074
ITGB4 integrin, beta 4 0.0318259
SLK STE20-like kinase 0.0314491
RAB22A RAB22A, member RAS oncogene family 0.0312327
DSTN destrin (actin depolymerizing factor) 0.0312145
UBE2H ubiquitin-conjugating enzyme E2H 0.0311893
BCL2L1 BCL2-like 1 0.0311408
PRRC2C proline-rich coiled-coil 2C 0.0310256
IGFBP6 insulin-like growth factor binding protein 6 0.0308114
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0305901
SOD2 superoxide dismutase 2, mitochondrial 0.0302802
ENO1 enolase 1, (alpha) 0.0302453
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.0301262
JMJD1C jumonji domain containing 1C 0.030087
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0298593
PTK2 protein tyrosine kinase 2 0.0295151
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0294922
RFX2 regulatory factor X, 2 (influences HLA class II expression) 0.0292757
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.0290729
LMNA lamin A/C 0.0288445
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0287431
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0286662
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.0284965
CEMIP cell migration inducing protein, hyaluronan binding 0.0284799
SPAG9 sperm associated antigen 9 0.028359
FAM107B family with sequence similarity 107, member B 0.0283557
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0283385
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0283068
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0279272
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.027885
SFTPA2 surfactant protein A2 0.0278644
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 0.0271435
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.0270788
SIK3 SIK family kinase 3 0.0270339
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0270037
TPM3 tropomyosin 3 0.0268469
ANXA1 annexin A1 0.0265849

decreased expression

Symbol Name Standardized Value
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 -0.0899648
TMSB10 thymosin beta 10 -0.0614753
RPS12 ribosomal protein S12 -0.0548218
RPLP2 ribosomal protein, large, P2 -0.0485754
RPS3 ribosomal protein S3 -0.0402025
TPT1 tumor protein, translationally-controlled 1 -0.0394898
RPL37A ribosomal protein L37a -0.0373918
RPS19 ribosomal protein S19 -0.0364096
RPS29 ribosomal protein S29 -0.035642
HMGA2 high mobility group AT-hook 2 -0.0347521
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.0334822
SULF1 sulfatase 1 -0.033222
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0311866
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.0307043
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0302906
WSB1 WD repeat and SOCS box containing 1 -0.0297702
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0263493
ACTG1 actin gamma 1 -0.0258258
SLC35F3 solute carrier family 35, member F3 -0.0252081
EGR1 early growth response 1 -0.0246033
RPS21 ribosomal protein S21 -0.0245522
RPL11 ribosomal protein L11 -0.0244244
PTMA prothymosin, alpha -0.023559
RPS25 ribosomal protein S25 -0.0233133
CSMD2 CUB and Sushi multiple domains 2 -0.0232927
RPL36 ribosomal protein L36 -0.023004
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.0228259
RPLP1 ribosomal protein, large, P1 -0.0224559
RPL7A ribosomal protein L7a -0.0220197
RPS16 ribosomal protein S16 -0.0218769
RPL28 ribosomal protein L28 -0.0211414
UQCRB ubiquinol-cytochrome c reductase binding protein -0.0207072
RPS23 ribosomal protein S23 -0.0204907
INTS6 integrator complex subunit 6 -0.0196767
RPS24 ribosomal protein S24 -0.0190999
POMP proteasome maturation protein -0.0189685
RPL31 ribosomal protein L31 -0.0186847
SLC38A2 solute carrier family 38, member 2 -0.0186761
RPS27A ribosomal protein S27a -0.0185983
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.0180585
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0177039
RPS6 ribosomal protein S6 -0.0170639
RPL37 ribosomal protein L37 -0.0168047
RPS20 ribosomal protein S20 -0.0163457
DPYD dihydropyrimidine dehydrogenase -0.0162437
IFI6 interferon, alpha-inducible protein 6 -0.0160391
ABI3BP ABI family, member 3 (NESH) binding protein -0.0159757
RPL9 ribosomal protein L9 -0.0158428
RPL30 ribosomal protein L30 -0.0158145
RPL38 ribosomal protein L38 -0.0157377
PKM pyruvate kinase, muscle -0.015663
RPS11 ribosomal protein S11 -0.0156039
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.0152941
RPL19 ribosomal protein L19 -0.0152003
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0151428
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -0.0147468
RPS8 ribosomal protein S8 -0.0144489
ENO2 enolase 2 (gamma, neuronal) -0.0144282
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.0144088
ANO1 anoctamin 1, calcium activated chloride channel -0.0143661
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0142772
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0140733
CTSD cathepsin D -0.0140422
PLXNA2 plexin A2 -0.0139849
ADIRF adipogenesis regulatory factor -0.0139441
IFITM3 interferon induced transmembrane protein 3 -0.0138945
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -0.0138394
LAMB3 laminin, beta 3 -0.0138152
RPL36A ribosomal protein L36a -0.0135952
CST3 cystatin C -0.013489
RPS17 ribosomal protein S17 -0.0133734
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.0133712
S100A11 S100 calcium binding protein A11 -0.0132775
RGS4 regulator of G-protein signaling 4 -0.0128885
RPL35A ribosomal protein L35a -0.0127628
ABLIM3 actin binding LIM protein family, member 3 -0.0126527
DUSP5 dual specificity phosphatase 5 -0.0125125
DIAPH3 diaphanous-related formin 3 -0.0124282
AHI1 Abelson helper integration site 1 -0.0123824
CMTM7 CKLF-like MARVEL transmembrane domain containing 7 -0.0123272
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0122274
SMYD3 SET and MYND domain containing 3 -0.0121792
DNAJC18 DnaJ (Hsp40) homolog, subfamily C, member 18 -0.0121601
RAD51B RAD51 paralog B -0.0120634
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -0.0117863
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 -0.0117596
ERI2 ERI1 exoribonuclease family member 2 -0.0116536
RAB7A RAB7A, member RAS oncogene family -0.0116276
OCIAD2 OCIA domain containing 2 -0.0115084
RPS15 ribosomal protein S15 -0.0113683
MT2A metallothionein 2A -0.0113644
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -0.0113126
NLRC5 NLR family, CARD domain containing 5 -0.0111812
COX7B cytochrome c oxidase subunit VIIb -0.0111641
AFG2A AFG2 AAA ATPase homolog A -0.0110384
DDIT3 DNA-damage-inducible transcript 3 -0.0109757
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.0109309
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -0.0109147
OFD1 oral-facial-digital syndrome 1 -0.0108966
CNRIP1 cannabinoid receptor interacting protein 1 -0.0107487