Oleic acid_J82 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Oleic acid perturbation in J82 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Oleic acid_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FTH1 ferritin, heavy polypeptide 1 0.170906
MYH9 myosin, heavy chain 9, non-muscle 0.0673328
INTS6 integrator complex subunit 6 0.0552908
AKAP12 A kinase (PRKA) anchor protein 12 0.046725
FLNA filamin A, alpha 0.0458171
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0411
PLEC plectin 0.0408331
TLE4 transducin-like enhancer of split 4 0.0394208
SLIT2 slit homolog 2 (Drosophila) 0.0391179
BZW1 basic leucine zipper and W2 domains 1 0.0382105
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0369622
ASPH aspartate beta-hydroxylase 0.0360174
DST dystonin 0.0357532
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0346854
EEF2 eukaryotic translation elongation factor 2 0.0341478
ANXA2 annexin A2 0.0336838
AHNAK AHNAK nucleoprotein 0.0313731
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0305933
HLA-C major histocompatibility complex, class I, C 0.0305732
EXT1 exostosin glycosyltransferase 1 0.0301886
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0301121
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0298074
ZSWIM6 zinc finger, SWIM-type containing 6 0.0296329
NAV2 neuron navigator 2 0.0294347
PDLIM5 PDZ and LIM domain 5 0.0284713
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.027416
HLA-E major histocompatibility complex, class I, E 0.0272258
KRT18 keratin 18, type I 0.0247089
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0246857
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0245122
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0237578
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0229423
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0224931
VCL vinculin 0.020818
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.0191425
TRIO trio Rho guanine nucleotide exchange factor 0.0190179
SEPTIN9 septin 9 0.0189626
ATXN1 ataxin 1 0.0189545
MYO1E myosin IE 0.0184601
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.0183915
MACF1 microtubule-actin crosslinking factor 1 0.0182798
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.0179601
SOD2 superoxide dismutase 2, mitochondrial 0.0177844
SMAD3 SMAD family member 3 0.0172713
ERBIN erbb2 interacting protein 0.017099
LPP LIM domain containing preferred translocation partner in lipoma 0.0169776
STIP1 stress-induced phosphoprotein 1 0.0169216
ANKRD33B ankyrin repeat domain 33B 0.0168979
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0168797
HSPH1 heat shock 105kDa/110kDa protein 1 0.0165796
MYO10 myosin X 0.0163291
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.0163198
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0161709
LOC102724023 ES1 protein homolog, mitochondrial 0.0161061
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0159613
AEBP2 AE binding protein 2 0.0156748
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.0155262
ERRFI1 ERBB receptor feedback inhibitor 1 0.0151849
DOCK5 dedicator of cytokinesis 5 0.0151545
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 0.0151301
CLIC4 chloride intracellular channel 4 0.0150432
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0149078
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0147057
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0146926
NABP1 nucleic acid binding protein 1 0.0144704
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0140398
PRELID2 PRELI domain containing 2 0.0139944
ADAM32 ADAM metallopeptidase domain 32 0.0138369
GOLGB1 golgin B1 0.0138346
ARHGAP29 Rho GTPase activating protein 29 0.0137466
MBNL1 muscleblind-like splicing regulator 1 0.0135452
KLF12 Kruppel-like factor 12 0.0132641
FRMD6 FERM domain containing 6 0.0131982
COL12A1 collagen, type XII, alpha 1 0.0131748
SP100 SP100 nuclear antigen 0.0130967
CALD1 caldesmon 1 0.0129536
SFTPA2 surfactant protein A2 0.0128829
RALY RALY heterogeneous nuclear ribonucleoprotein 0.0128594
SAMD4A sterile alpha motif domain containing 4A 0.0128501
SNX14 sorting nexin 14 0.0127287
PHF3 PHD finger protein 3 0.012718
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.0126654
DSCAM Down syndrome cell adhesion molecule 0.0126211
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0125571
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0125117
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.01238
SIPA1L3 signal-induced proliferation-associated 1 like 3 0.0123354
AGO3 argonaute RISC catalytic component 3 0.0123013
LIMA1 LIM domain and actin binding 1 0.0122445
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0122255
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.012213
SHB Src homology 2 domain containing adaptor protein B 0.0120908
LARP4B La ribonucleoprotein domain family, member 4B 0.0118772
BCAR3 breast cancer anti-estrogen resistance 3 0.0117788
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.0116224
FSTL1 follistatin-like 1 0.0115406
STARD13 StAR-related lipid transfer (START) domain containing 13 0.0111928
SQSTM1 sequestosome 1 0.0111591
FHL2 four and a half LIM domains 2 0.0111378
CAPN2 calpain 2, (m/II) large subunit 0.0110755

decreased expression

Symbol Name Standardized Value
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0982747
HLA-B major histocompatibility complex, class I, B -0.0869699
MT2A metallothionein 2A -0.0831368
TMSB10 thymosin beta 10 -0.0725718
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0609805
MT1X metallothionein 1X -0.0594593
NALF1 NALCN channel auxiliary factor 1 -0.0563831
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0554727
ABI3BP ABI family, member 3 (NESH) binding protein -0.0512252
FTL ferritin, light polypeptide -0.0495801
PTMA prothymosin, alpha -0.0468778
NAMPT nicotinamide phosphoribosyltransferase -0.0442641
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0436154
SLC12A8 solute carrier family 12, member 8 -0.0426166
RPLP2 ribosomal protein, large, P2 -0.0402763
UBC ubiquitin C -0.0393094
ENO1 enolase 1, (alpha) -0.0364908
PFN1 profilin 1 -0.0355749
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0333054
DLG1 discs, large homolog 1 (Drosophila) -0.0326448
IGFBP3 insulin-like growth factor binding protein 3 -0.0318608
UGCG UDP-glucose ceramide glucosyltransferase -0.0312254
B2M beta-2-microglobulin -0.0310231
RPL23 ribosomal protein L23 -0.0300178
ATP13A3 ATPase type 13A3 -0.0298249
POTEF POTE ankyrin domain family, member F -0.0297425
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -0.0275597
WSB1 WD repeat and SOCS box containing 1 -0.027532
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -0.0274009
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0271035
RPL35A ribosomal protein L35a -0.0262384
PCBP2 poly(rC) binding protein 2 -0.0256826
PDIA3 protein disulfide isomerase family A, member 3 -0.0252852
VIM vimentin -0.0251882
DEK DEK proto-oncogene -0.0239844
IFI6 interferon, alpha-inducible protein 6 -0.0239742
RPS6 ribosomal protein S6 -0.0229513
GOLGA4 golgin A4 -0.0225347
PPME1 protein phosphatase methylesterase 1 -0.0225343
EIF4A1 eukaryotic translation initiation factor 4A1 -0.022481
POSTN periostin, osteoblast specific factor -0.0219844
TPI1 triosephosphate isomerase 1 -0.0215244
ARF4 ADP-ribosylation factor 4 -0.0215128
CCBE1 collagen and calcium binding EGF domains 1 -0.0207487
RBM39 RNA binding motif protein 39 -0.0206765
RPS19 ribosomal protein S19 -0.0205739
RPS21 ribosomal protein S21 -0.0205733
CTSD cathepsin D -0.0201506
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0200339
S100A6 S100 calcium binding protein A6 -0.0195011
CALR calreticulin -0.018875
MYL12B myosin, light chain 12B, regulatory -0.0187347
PKM pyruvate kinase, muscle -0.0186298
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -0.0183556
NPEPPS aminopeptidase puromycin sensitive -0.0179615
RBM25 RNA binding motif protein 25 -0.0178551
RPS13 ribosomal protein S13 -0.0175691
IFITM3 interferon induced transmembrane protein 3 -0.0174857
TMEM41B transmembrane protein 41B -0.0171371
TPM1 tropomyosin 1 (alpha) -0.0170148
PLCB4 phospholipase C, beta 4 -0.0169457
MMP12 matrix metallopeptidase 12 -0.0167152
RPL35 ribosomal protein L35 -0.0167105
SRSF11 serine/arginine-rich splicing factor 11 -0.0162074
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.016145
RPL37 ribosomal protein L37 -0.0160545
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0160401
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0159974
RPL28 ribosomal protein L28 -0.0159056
TFG TRK-fused gene -0.0158322
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0154128
F3 coagulation factor III (thromboplastin, tissue factor) -0.0153944
KPNB1 karyopherin (importin) beta 1 -0.0153803
OSMR oncostatin M receptor -0.0153293
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0152962
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -0.0147195
TXNRD1 thioredoxin reductase 1 -0.014586
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.0144754
NAP1L1 nucleosome assembly protein 1-like 1 -0.0144169
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0143879
PTBP3 polypyrimidine tract binding protein 3 -0.013909
BASP1 brain abundant, membrane attached signal protein 1 -0.0138356
CANX calnexin -0.0138257
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -0.0137427
MATR3 matrin 3 -0.013672
RPL36A ribosomal protein L36a -0.0136548
PGK1 phosphoglycerate kinase 1 -0.0136462
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.0136096
IPO7 importin 7 -0.0135896
POMP proteasome maturation protein -0.0135111
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -0.0133694
SEPTIN7 septin 7 -0.0133425
S100A11 S100 calcium binding protein A11 -0.0133394
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.0133282
JUN jun proto-oncogene -0.0133103
VMP1 vacuole membrane protein 1 -0.0131133
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0130534
NPPB natriuretic peptide B -0.013012
IFITM1 interferon induced transmembrane protein 1 -0.0129743
RPS3 ribosomal protein S3 -0.0129259