Oleic acid_LoVo Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Oleic acid perturbation in LoVo cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Oleic acid_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
KRT18 keratin 18, type I 0.0975542
LMO7 LIM domain 7 0.0965213
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.0893601
EZR ezrin 0.0848933
EEF2 eukaryotic translation elongation factor 2 0.0778688
MYO1E myosin IE 0.0753118
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0745829
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0697658
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 0.0662561
DSPP dentin sialophosphoprotein 0.064622
ITPRID2 ITPR interacting domain containing 2 0.06378
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.058238
F3 coagulation factor III (thromboplastin, tissue factor) 0.0512059
MSI2 musashi RNA-binding protein 2 0.0499744
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0485019
ZSWIM6 zinc finger, SWIM-type containing 6 0.0462456
MPRIP myosin phosphatase Rho interacting protein 0.0460334
OXSR1 oxidative stress responsive 1 0.0457239
FAT1 FAT atypical cadherin 1 0.0430085
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0427351
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.0411802
MYH14 myosin, heavy chain 14, non-muscle 0.0393058
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0392847
LOC112694756 uncharaterized LOC112694756 0.0379633
FRMD5 FERM domain containing 5 0.0379082
DSG2 desmoglein 2 0.0369766
CATSPERB catsper channel auxiliary subunit beta 0.0368933
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.03685
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0360771
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0356193
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.0352977
AKAP13 A kinase (PRKA) anchor protein 13 0.0349506
PDLIM5 PDZ and LIM domain 5 0.0343638
LPP LIM domain containing preferred translocation partner in lipoma 0.0340187
SLTM SAFB-like, transcription modulator 0.0339937
FBXO11 F-box protein 11 0.0336013
PTPRB protein tyrosine phosphatase, receptor type, B 0.0329062
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0321289
PSD3 pleckstrin and Sec7 domain containing 3 0.032061
MYO5B myosin VB 0.0320417
INTS6 integrator complex subunit 6 0.0318722
EIF4A2 eukaryotic translation initiation factor 4A2 0.0309292
ITGB4 integrin, beta 4 0.0308566
POTEF POTE ankyrin domain family, member F 0.0304727
CUX1 cut-like homeobox 1 0.0302931
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0299254
PKM pyruvate kinase, muscle 0.0296545
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0296048
THSD4 thrombospondin, type I, domain containing 4 0.0293679
ESYT2 extended synaptotagmin-like protein 2 0.0291467
SP100 SP100 nuclear antigen 0.0288299
PTBP3 polypyrimidine tract binding protein 3 0.0287173
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.0283333
CALB1 calbindin 1, 28kDa 0.0280181
ZCCHC7 zinc finger, CCHC domain containing 7 0.0279238
LOC105378220 macrophage receptor MARCO-like 0.0273685
LOC102724023 ES1 protein homolog, mitochondrial 0.0270165
SVIL supervillin 0.0269002
TJP1 tight junction protein 1 0.0266837
LDHA lactate dehydrogenase A 0.0264829
MYH9 myosin, heavy chain 9, non-muscle 0.026455
NPSR1 neuropeptide S receptor 1 0.026118
ALCAM activated leukocyte cell adhesion molecule 0.0259764
STK39 serine threonine kinase 39 0.0259118
EGFR epidermal growth factor receptor 0.0257592
RCOR1 REST corepressor 1 0.0256649
KRT8 keratin 8, type II 0.0256642
GMDS GDP-mannose 4,6-dehydratase 0.0253294
AHNAK AHNAK nucleoprotein 0.0252697
SLCO1B3-SLCO1B7 SLCO1B3-SLCO1B7 readthrough 0.0252606
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0249871
KTN1 kinectin 1 (kinesin receptor) 0.0248568
RPL3 ribosomal protein L3 0.0247808
DIAPH1 diaphanous-related formin 1 0.0247036
PCBP2 poly(rC) binding protein 2 0.0247028
PLEC plectin 0.0246352
PELI1 pellino E3 ubiquitin protein ligase 1 0.0243386
ANXA2 annexin A2 0.0239559
MACF1 microtubule-actin crosslinking factor 1 0.0239389
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.0239367
NCOR2 nuclear receptor corepressor 2 0.0232469
BRD2 bromodomain containing 2 0.0232375
APP amyloid beta (A4) precursor protein 0.0231365
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0230962
CAV2 caveolin 2 0.0230955
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.023067
HSPA8 heat shock 70kDa protein 8 0.0225441
FMNL2 formin-like 2 0.0222512
RIMKLB ribosomal modification protein rimK-like family member B 0.0221946
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 0.0221337
PTK2 protein tyrosine kinase 2 0.0217701
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative) 0.0217256
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0216016
PGK1 phosphoglycerate kinase 1 0.0214607
DST dystonin 0.0214458
RABGAP1L RAB GTPase activating protein 1-like 0.0212831
MAML2 mastermind-like 2 (Drosophila) 0.0212721
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0212404
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.0211835
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.0205505

decreased expression

Symbol Name Standardized Value
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.131139
RPLP1 ribosomal protein, large, P1 -0.116774
TPT1 tumor protein, translationally-controlled 1 -0.114047
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.109894
TMSB10 thymosin beta 10 -0.0757944
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0755931
RPS12 ribosomal protein S12 -0.0661589
RPLP2 ribosomal protein, large, P2 -0.0645576
RPL35A ribosomal protein L35a -0.0644915
RPS19 ribosomal protein S19 -0.0602783
RPL13A ribosomal protein L13a -0.0582364
RPL26 ribosomal protein L26 -0.0575932
RPL37A ribosomal protein L37a -0.0569512
PKP2 plakophilin 2 -0.054962
PRELID2 PRELI domain containing 2 -0.0548613
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0546627
RPS8 ribosomal protein S8 -0.0530573
RPS29 ribosomal protein S29 -0.0504461
TXNRD1 thioredoxin reductase 1 -0.0500555
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0488777
PRSS3 protease, serine, 3 -0.047355
RPS23 ribosomal protein S23 -0.0471579
GARS1 glycyl-tRNA synthetase 1 -0.045617
RPS6 ribosomal protein S6 -0.0454356
RPLP0 ribosomal protein, large, P0 -0.0452845
RPL23 ribosomal protein L23 -0.0450678
RPL34 ribosomal protein L34 -0.0446075
RPL9 ribosomal protein L9 -0.044219
RPS27A ribosomal protein S27a -0.0439461
RPS3 ribosomal protein S3 -0.0424908
RPS21 ribosomal protein S21 -0.0409201
RPS24 ribosomal protein S24 -0.0407279
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0401068
RPL12 ribosomal protein L12 -0.0397972
ABHD17C abhydrolase domain containing 17C -0.0364472
BTBD9 BTB (POZ) domain containing 9 -0.0359019
RPS25 ribosomal protein S25 -0.035556
RPS16 ribosomal protein S16 -0.0353805
PTMA prothymosin, alpha -0.0350196
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0339662
RPL28 ribosomal protein L28 -0.0339279
EIF1 eukaryotic translation initiation factor 1 -0.0335669
RPL36 ribosomal protein L36 -0.0334873
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.0318106
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0315155
RPL11 ribosomal protein L11 -0.0312043
GOLGA4 golgin A4 -0.0310535
GDF15 growth differentiation factor 15 -0.0306213
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0300625
RBM39 RNA binding motif protein 39 -0.0291396
RPS20 ribosomal protein S20 -0.028973
RPS13 ribosomal protein S13 -0.0288907
RPS17 ribosomal protein S17 -0.0282651
PNISR PNN-interacting serine/arginine-rich protein -0.0282096
RPL38 ribosomal protein L38 -0.027676
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0275366
KCNK1 potassium channel, two pore domain subfamily K, member 1 -0.0275281
ARHGAP29 Rho GTPase activating protein 29 -0.0273438
RPL37 ribosomal protein L37 -0.0272838
RPL30 ribosomal protein L30 -0.0267281
MON2 MON2 homolog (S. cerevisiae) -0.0263158
RPL27A ribosomal protein L27a -0.0260334
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -0.0255645
EREG epiregulin -0.025234
ATXN1 ataxin 1 -0.0247519
RPL5 ribosomal protein L5 -0.0247137
PRAG1 PEAK1 related, kinase-activating pseudokinase 1 -0.0245279
RPL4 ribosomal protein L4 -0.0245128
RPL31 ribosomal protein L31 -0.0245053
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0240184
TMEM45B transmembrane protein 45B -0.0236198
RPL32 ribosomal protein L32 -0.0234551
RFX3 regulatory factor X, 3 (influences HLA class II expression) -0.0234418
SHROOM3 shroom family member 3 -0.0233984
WARS1 tryptophanyl-tRNA synthetase 1 -0.0230021
RAD21 RAD21 homolog (S. pombe) -0.022599
SMYD3 SET and MYND domain containing 3 -0.0224296
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme -0.0222837
RPS5 ribosomal protein S5 -0.0222734
PLAC8 placenta-specific 8 -0.0222298
PCDHB16 protocadherin beta 16 -0.0219825
RPS15 ribosomal protein S15 -0.0219243
RRBP1 ribosome binding protein 1 -0.0218854
HMGB2 high mobility group box 2 -0.0218164
CXADR coxsackie virus and adenovirus receptor -0.0217666
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0215341
ZFAND3 zinc finger, AN1-type domain 3 -0.0210312
NAP1L1 nucleosome assembly protein 1-like 1 -0.0208106
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0207844
CEP95 centrosomal protein 95kDa -0.0205347
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0203474
S100P S100 calcium binding protein P -0.0203341
COG5 component of oligomeric golgi complex 5 -0.0202321
UQCRB ubiquinol-cytochrome c reductase binding protein -0.02017
AVL9 AVL9 homolog (S. cerevisiase) -0.0199952
RPL36A ribosomal protein L36a -0.0197563
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 -0.0196728
OGA O-GlcNAcase -0.0194684
MATR3 matrin 3 -0.0193058
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) -0.019146