Oleic acid_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Oleic acid perturbation in SNU-1 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Oleic acid_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
SOX6 SRY (sex determining region Y)-box 6 0.0467721
PDGFC platelet derived growth factor C 0.0446508
HDAC9 histone deacetylase 9 0.0387155
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0368615
TJP1 tight junction protein 1 0.0354911
SSBP2 single-stranded DNA binding protein 2 0.035267
BMP2K BMP2 inducible kinase 0.0319029
PDE4B phosphodiesterase 4B, cAMP-specific 0.0314627
ZEB1 zinc finger E-box binding homeobox 1 0.0277531
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.0268484
ECT2 epithelial cell transforming 2 0.0226044
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0218092
EEF2 eukaryotic translation elongation factor 2 0.0205264
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0200428
QKI QKI, KH domain containing, RNA binding 0.019693
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 0.0183105
EML4 echinoderm microtubule associated protein like 4 0.017835
MYO5C myosin VC 0.0177586
SYNE2 spectrin repeat containing, nuclear envelope 2 0.017505
DPYD dihydropyrimidine dehydrogenase 0.0170112
NCKAP1 NCK-associated protein 1 0.0154074
CDC73 cell division cycle 73 0.0147888
NUP58 nucleoporin 58 0.0147378
GLI3 GLI family zinc finger 3 0.0144208
TGFBR3 transforming growth factor, beta receptor III 0.0143938
EVI5 ecotropic viral integration site 5 0.014365
HELZ helicase with zinc finger 0.0143071
USP47 ubiquitin specific peptidase 47 0.0143012
ANXA1 annexin A1 0.0142665
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0141841
MKI67 marker of proliferation Ki-67 0.0139582
RNF145 ring finger protein 145 0.0134617
MACROD2 MACRO domain containing 2 0.0133119
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0132855
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0131872
GSPT1 G1 to S phase transition 1 0.0131742
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0131093
DHFR dihydrofolate reductase 0.0130557
CCNL1 cyclin L1 0.0127704
PRELID2 PRELI domain containing 2 0.0123871
ITCH itchy E3 ubiquitin protein ligase 0.0123399
FBLN2 fibulin 2 0.0122924
DIAPH3 diaphanous-related formin 3 0.0122898
ZBTB38 zinc finger and BTB domain containing 38 0.0122163
TOB1 transducer of ERBB2, 1 0.0121215
ZNF608 zinc finger protein 608 0.0120932
FAT1 FAT atypical cadherin 1 0.0119025
SEPTIN11 septin 11 0.0114392
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0113793
ADAM10 ADAM metallopeptidase domain 10 0.0113393
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.0113284
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 0.0112182
TMEM65 transmembrane protein 65 0.0108732
LNPEP leucyl/cystinyl aminopeptidase 0.0108688
CNOT1 CCR4-NOT transcription complex, subunit 1 0.010817
LOC112694756 uncharaterized LOC112694756 0.0107801
ZFR zinc finger RNA binding protein 0.0107184
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0106039
YAP1 Yes-associated protein 1 0.0105683
ZCCHC8 zinc finger, CCHC domain containing 8 0.0105355
USP24 ubiquitin specific peptidase 24 0.0104455
GLS2 glutaminase 2 (liver, mitochondrial) 0.0104123
NCAPD2 non-SMC condensin I complex, subunit D2 0.0103934
MBNL2 muscleblind-like splicing regulator 2 0.0102075
UBA6 ubiquitin-like modifier activating enzyme 6 0.0101577
TSC22D1 TSC22 domain family, member 1 0.010124
CNOT6L CCR4-NOT transcription complex, subunit 6-like 0.0101196
ZNF292 zinc finger protein 292 0.0100573
FXR1 fragile X mental retardation, autosomal homolog 1 0.00988968
ARID1A AT rich interactive domain 1A (SWI-like) 0.00983622
MEF2A myocyte enhancer factor 2A 0.0098123
TPX2 TPX2, microtubule-associated 0.00978898
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.00968092
LPP LIM domain containing preferred translocation partner in lipoma 0.00958574
WDR33 WD repeat domain 33 0.00958005
LONRF2 LON peptidase N-terminal domain and ring finger 2 0.00955066
NAV2 neuron navigator 2 0.00931251
PKP4 plakophilin 4 0.00921975
KIF5C kinesin family member 5C 0.00919024
SMAD6 SMAD family member 6 0.00915863
SFTPA2 surfactant protein A2 0.00915585
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.00907719
EXOC4 exocyst complex component 4 0.00902753
EPC2 enhancer of polycomb homolog 2 (Drosophila) 0.00900879
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.00889691
NAMPT nicotinamide phosphoribosyltransferase 0.00889187
KDM6A lysine (K)-specific demethylase 6A 0.00883886
SPTBN1 spectrin, beta, non-erythrocytic 1 0.00877609
COPA coatomer protein complex, subunit alpha 0.00876945
PCGF5 polycomb group ring finger 5 0.0087638
TBC1D5 TBC1 domain family, member 5 0.00876092
PLK2 polo-like kinase 2 0.00873489
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.00872691
RAB27B RAB27B, member RAS oncogene family 0.00872388
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.00864819
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.00859672
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.00857213
TRIOBP TRIO and F-actin binding protein 0.00854507
TXNIP thioredoxin interacting protein 0.00853782
H1-4 H1.4 linker histone, cluster member 0.00829363

decreased expression

Symbol Name Standardized Value
PTMA prothymosin, alpha -0.353759
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.213352
TPT1 tumor protein, translationally-controlled 1 -0.113362
RPS6 ribosomal protein S6 -0.0955994
RPL35A ribosomal protein L35a -0.0838641
RPS8 ribosomal protein S8 -0.0822015
RPS27A ribosomal protein S27a -0.0764225
RPL31 ribosomal protein L31 -0.0704324
RPL37A ribosomal protein L37a -0.0668077
RPLP1 ribosomal protein, large, P1 -0.066529
RPS3 ribosomal protein S3 -0.0657397
RPL26 ribosomal protein L26 -0.0637295
RPL23 ribosomal protein L23 -0.0620324
RPS13 ribosomal protein S13 -0.061923
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0593469
RPS23 ribosomal protein S23 -0.0592611
S100A6 S100 calcium binding protein A6 -0.0585164
RPL34 ribosomal protein L34 -0.0580173
RPL9 ribosomal protein L9 -0.0573487
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0553273
RPS25 ribosomal protein S25 -0.0540525
RPLP2 ribosomal protein, large, P2 -0.0535993
ACTG1 actin gamma 1 -0.0523162
UBC ubiquitin C -0.0510354
EIF1 eukaryotic translation initiation factor 1 -0.0487794
RPS12 ribosomal protein S12 -0.0487706
RPL19 ribosomal protein L19 -0.0486507
RPL11 ribosomal protein L11 -0.0472876
RPS19 ribosomal protein S19 -0.0467467
RPS29 ribosomal protein S29 -0.0450792
S100A9 S100 calcium binding protein A9 -0.0408682
PKM pyruvate kinase, muscle -0.0403287
RPL36 ribosomal protein L36 -0.0397656
RPL8 ribosomal protein L8 -0.0375157
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0366702
RPS21 ribosomal protein S21 -0.0366517
RPS24 ribosomal protein S24 -0.0365649
NAP1L1 nucleosome assembly protein 1-like 1 -0.0365118
MYL12B myosin, light chain 12B, regulatory -0.0350409
ENO2 enolase 2 (gamma, neuronal) -0.0344535
RPL5 ribosomal protein L5 -0.0339174
RPL38 ribosomal protein L38 -0.0329625
TMSB10 thymosin beta 10 -0.0327537
RPL12 ribosomal protein L12 -0.0327253
RPL13A ribosomal protein L13a -0.032081
FLNB filamin B, beta -0.0320118
ENO1 enolase 1, (alpha) -0.0318401
RPL7A ribosomal protein L7a -0.0318265
AHNAK AHNAK nucleoprotein -0.0316038
RPL30 ribosomal protein L30 -0.0313856
RPL37 ribosomal protein L37 -0.0310235
RPS27 ribosomal protein S27 -0.0309417
FTL ferritin, light polypeptide -0.0308401
S100A10 S100 calcium binding protein A10 -0.0291524
RPS16 ribosomal protein S16 -0.0290041
HSPB1 heat shock 27kDa protein 1 -0.0287908
WSB1 WD repeat and SOCS box containing 1 -0.0287261
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.0275539
RPL32 ribosomal protein L32 -0.0268246
UQCRB ubiquinol-cytochrome c reductase binding protein -0.0264292
RPS17 ribosomal protein S17 -0.0263705
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0263208
RPL28 ribosomal protein L28 -0.0259528
ZMYND8 zinc finger, MYND-type containing 8 -0.0258534
LDHA lactate dehydrogenase A -0.025816
RPL15 ribosomal protein L15 -0.0258065
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0253552
B2M beta-2-microglobulin -0.0240801
RPS5 ribosomal protein S5 -0.0238158
RPS15 ribosomal protein S15 -0.0235824
RPL36A ribosomal protein L36a -0.0235073
ASPH aspartate beta-hydroxylase -0.0231525
RPS10 ribosomal protein S10 -0.022973
CCND1 cyclin D1 -0.022279
HLA-B major histocompatibility complex, class I, B -0.0222696
RPL27A ribosomal protein L27a -0.0221451
RPS11 ribosomal protein S11 -0.0219978
RACK1 receptor for activated C kinase 1 -0.0216572
TM4SF1 transmembrane 4 L six family member 1 -0.0216075
MT2A metallothionein 2A -0.0215707
VIM vimentin -0.0213802
RPS14 ribosomal protein S14 -0.0212343
KPNB1 karyopherin (importin) beta 1 -0.0207652
RPL10A ribosomal protein L10a -0.0207361
RPL35 ribosomal protein L35 -0.0204052
RPLP0 ribosomal protein, large, P0 -0.0199224
IFITM3 interferon induced transmembrane protein 3 -0.0198272
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0194448
RPL7 ribosomal protein L7 -0.0193977
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.0193304
COX4I1 cytochrome c oxidase subunit IV isoform 1 -0.019158
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0190233
IFI16 interferon, gamma-inducible protein 16 -0.0182238
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0177655
ZFAND3 zinc finger, AN1-type domain 3 -0.0176812
EIF4A1 eukaryotic translation initiation factor 4A1 -0.0175334
RTN4 reticulon 4 -0.0174518
BMP10 bone morphogenetic protein 10 -0.01727
RPL18 ribosomal protein L18 -0.0172189
ATF4 activating transcription factor 4 -0.0171978