Oleic acid_SNU-423 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Oleic acid perturbation in SNU-423 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Oleic acid_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
SOD2 superoxide dismutase 2, mitochondrial 0.297074
EEF2 eukaryotic translation elongation factor 2 0.204142
FN1 fibronectin 1 0.182452
MYH9 myosin, heavy chain 9, non-muscle 0.163961
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.147784
SFTPA2 surfactant protein A2 0.0964309
FTH1 ferritin, heavy polypeptide 1 0.0854372
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0840138
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.0765318
FNDC3B fibronectin type III domain containing 3B 0.0743708
HDAC9 histone deacetylase 9 0.0742834
UGCG UDP-glucose ceramide glucosyltransferase 0.0726443
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0716368
SPAG9 sperm associated antigen 9 0.0645172
FLNA filamin A, alpha 0.0640476
NAV2 neuron navigator 2 0.0639631
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0631797
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0600429
SMAD3 SMAD family member 3 0.0588639
VEGFA vascular endothelial growth factor A 0.0580713
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0575594
ARRDC3 arrestin domain containing 3 0.0563727
LOC112694756 uncharaterized LOC112694756 0.0500323
TRIO trio Rho guanine nucleotide exchange factor 0.0492007
LAMP2 lysosomal-associated membrane protein 2 0.0486152
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0461414
TNIP1 TNFAIP3 interacting protein 1 0.0460401
MSN moesin 0.0459409
CD44 CD44 molecule (Indian blood group) 0.0458181
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0455242
UBA6 ubiquitin-like modifier activating enzyme 6 0.0447167
TSC22D2 TSC22 domain family, member 2 0.0443529
HELZ helicase with zinc finger 0.0441948
ZNF292 zinc finger protein 292 0.0439243
APLP2 amyloid beta (A4) precursor-like protein 2 0.0436292
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0429467
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0425686
ZMIZ1 zinc finger, MIZ-type containing 1 0.04222
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0415516
USP9X ubiquitin specific peptidase 9, X-linked 0.0406766
JMJD1C jumonji domain containing 1C 0.0403281
TENT5A terminal nucleotidyltransferase 5A 0.0401413
ICAM1 intercellular adhesion molecule 1 0.0398643
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.0396906
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0389705
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0383631
RPS4X ribosomal protein S4, X-linked 0.0379654
YBX1 Y box binding protein 1 0.0378914
ANXA2 annexin A2 0.037808
MYOF myoferlin 0.0371475
PCBP2 poly(rC) binding protein 2 0.0371391
CCNL1 cyclin L1 0.0357129
SOX9 SRY (sex determining region Y)-box 9 0.0355209
SHB Src homology 2 domain containing adaptor protein B 0.035043
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0349787
CADM1 cell adhesion molecule 1 0.0345392
TXNIP thioredoxin interacting protein 0.0345339
ATXN1 ataxin 1 0.0339358
OGA O-GlcNAcase 0.033246
WTAP Wilms tumor 1 associated protein 0.0331475
KYNU kynureninase 0.0328037
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.0324436
RB1CC1 RB1-inducible coiled-coil 1 0.0323754
EDIL3 EGF-like repeats and discoidin I-like domains 3 0.0322312
CENPF centromere protein F, 350/400kDa 0.0319644
OPTN optineurin 0.0317217
KMT2E lysine (K)-specific methyltransferase 2E 0.0315017
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.031394
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.0300797
PPARD peroxisome proliferator-activated receptor delta 0.0298439
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.0293047
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.0292845
EXT1 exostosin glycosyltransferase 1 0.0292309
APP amyloid beta (A4) precursor protein 0.029169
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0287605
ANLN anillin, actin binding protein 0.0284407
FXR1 fragile X mental retardation, autosomal homolog 1 0.028279
SDC4 syndecan 4 0.0282496
RUNX1 runt-related transcription factor 1 0.0281015
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0280442
AHR aryl hydrocarbon receptor 0.0279871
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0279832
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0276302
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.0275168
VCAN versican 0.0272847
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0272707
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0270141
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.026987
SNX9 sorting nexin 9 0.0268696
EPS8 epidermal growth factor receptor pathway substrate 8 0.026716
ELL2 elongation factor, RNA polymerase II, 2 0.0267158
EEF1G eukaryotic translation elongation factor 1 gamma 0.0266575
MBNL1 muscleblind-like splicing regulator 1 0.0265798
MKI67 marker of proliferation Ki-67 0.0262333
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0258026
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.0252875
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0248959
GOLGA4 golgin A4 0.0246385
GLS2 glutaminase 2 (liver, mitochondrial) 0.0243046
NONO non-POU domain containing, octamer-binding 0.024209

decreased expression

Symbol Name Standardized Value
VIM vimentin -0.241589
TPT1 tumor protein, translationally-controlled 1 -0.131113
IGFBP3 insulin-like growth factor binding protein 3 -0.103826
AKAP12 A kinase (PRKA) anchor protein 12 -0.103465
ZMYND8 zinc finger, MYND-type containing 8 -0.102653
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0923401
TMSB10 thymosin beta 10 -0.0816277
HLA-B major histocompatibility complex, class I, B -0.0770754
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.0719299
GLIS3 GLIS family zinc finger 3 -0.0625021
RPL37A ribosomal protein L37a -0.06166
RAI14 retinoic acid induced 14 -0.0548741
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0531844
IER3 immediate early response 3 -0.0513864
FTL ferritin, light polypeptide -0.0510186
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0505301
CDH13 cadherin 13 -0.0493145
SLC38A1 solute carrier family 38, member 1 -0.0491964
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough -0.0482837
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0478803
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0459759
NAMPT nicotinamide phosphoribosyltransferase -0.0448108
RPL36A ribosomal protein L36a -0.0432291
RPS12 ribosomal protein S12 -0.0413034
FRMD4A FERM domain containing 4A -0.039604
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A -0.0387059
IFI16 interferon, gamma-inducible protein 16 -0.0383286
RPS3 ribosomal protein S3 -0.038048
TPM4 tropomyosin 4 -0.0369518
AFF3 AF4/FMR2 family, member 3 -0.0362037
WSB1 WD repeat and SOCS box containing 1 -0.0358886
RPLP2 ribosomal protein, large, P2 -0.0353701
COL1A1 collagen, type I, alpha 1 -0.035196
RRBP1 ribosome binding protein 1 -0.0350029
HMGA2 high mobility group AT-hook 2 -0.0346387
RPS24 ribosomal protein S24 -0.0345497
EGFR epidermal growth factor receptor -0.0341232
BTG1 B-cell translocation gene 1, anti-proliferative -0.0340146
FRMPD4 FERM and PDZ domain containing 4 -0.0339023
IFI6 interferon, alpha-inducible protein 6 -0.0338584
DIAPH2 diaphanous-related formin 2 -0.033655
RPL9 ribosomal protein L9 -0.0335675
CLMP CXADR-like membrane protein -0.0323924
RPS8 ribosomal protein S8 -0.032385
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.032255
RPS29 ribosomal protein S29 -0.0319784
IFITM3 interferon induced transmembrane protein 3 -0.0318982
RPL35A ribosomal protein L35a -0.0318023
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0304766
CAVIN1 caveolae associated protein 1 -0.0303296
RPL31 ribosomal protein L31 -0.0293898
PTMA prothymosin, alpha -0.029276
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -0.0292565
ENO2 enolase 2 (gamma, neuronal) -0.0291533
BASP1 brain abundant, membrane attached signal protein 1 -0.0288079
RPL38 ribosomal protein L38 -0.0282534
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0281716
RPS13 ribosomal protein S13 -0.0279562
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0276323
ARL4C ADP-ribosylation factor-like 4C -0.027431
RPL26 ribosomal protein L26 -0.0272712
SLC38A2 solute carrier family 38, member 2 -0.0271815
RPL37 ribosomal protein L37 -0.0269666
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 -0.0263834
SAMD3 sterile alpha motif domain containing 3 -0.0262149
KPNB1 karyopherin (importin) beta 1 -0.0260811
RPS27A ribosomal protein S27a -0.0260751
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.0256298
TMEM132D transmembrane protein 132D -0.0253462
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0252511
SDK1 sidekick cell adhesion molecule 1 -0.0249397
GNAS GNAS complex locus -0.0247589
TCEAL4 transcription elongation factor A (SII)-like 4 -0.0246547
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 -0.024248
RPL36 ribosomal protein L36 -0.0237311
ACTG1 actin gamma 1 -0.0234334
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0231334
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -0.0230458
DNAAF9 dynein axonemal assembly factor 9 -0.0229687
SOX5 SRY (sex determining region Y)-box 5 -0.0222459
SOX4 SRY (sex determining region Y)-box 4 -0.0222092
RPS23 ribosomal protein S23 -0.0220775
RPS25 ribosomal protein S25 -0.0219572
ADAM12 ADAM metallopeptidase domain 12 -0.0218158
ZFHX3 zinc finger homeobox 3 -0.0216778
ATRX alpha thalassemia/mental retardation syndrome X-linked -0.0215553
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0215175
ISG15 ISG15 ubiquitin-like modifier -0.0212463
KRT19 keratin 19, type I -0.0211822
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0209857
BNC2 basonuclin 2 -0.0207714
HM13 histocompatibility (minor) 13 -0.020717
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0204925
CP ceruloplasmin (ferroxidase) -0.0203136
SFRP1 secreted frizzled-related protein 1 -0.0202346
INHBA inhibin, beta A -0.0200402
MMP12 matrix metallopeptidase 12 -0.0199905
GREM1 gremlin 1, DAN family BMP antagonist -0.0197525
DENND2A DENN/MADD domain containing 2A -0.0196711
RPL34 ribosomal protein L34 -0.0194149