Oleic acid_SW1417 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Oleic acid perturbation in SW1417 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Oleic acid_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.11412
NCEH1 neutral cholesterol ester hydrolase 1 0.109454
BCL2L1 BCL2-like 1 0.10824
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.102696
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.100596
MAML2 mastermind-like 2 (Drosophila) 0.099296
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0821167
NEBL nebulette 0.0806919
MYO1E myosin IE 0.0757653
CEMIP cell migration inducing protein, hyaluronan binding 0.0733564
VCL vinculin 0.0712769
FNDC3B fibronectin type III domain containing 3B 0.070651
FAT1 FAT atypical cadherin 1 0.0674935
EHBP1 EH domain binding protein 1 0.0659689
KRT18 keratin 18, type I 0.0620341
PMEPA1 prostate transmembrane protein, androgen induced 1 0.06123
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0588305
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0586471
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0585676
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0564131
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0546577
SAMD4A sterile alpha motif domain containing 4A 0.0546262
OSBPL10 oxysterol binding protein-like 10 0.0542658
SDK1 sidekick cell adhesion molecule 1 0.0537201
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0533601
ZBTB20 zinc finger and BTB domain containing 20 0.0529924
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0529031
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.0506417
SMAD3 SMAD family member 3 0.0505511
ZSWIM6 zinc finger, SWIM-type containing 6 0.050506
PCSK5 proprotein convertase subtilisin/kexin type 5 0.0495577
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 0.049509
PLEC plectin 0.0474344
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.047411
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0472901
LPP LIM domain containing preferred translocation partner in lipoma 0.0470405
MACC1 metastasis associated in colon cancer 1 0.0462859
YAP1 Yes-associated protein 1 0.0451683
GMDS GDP-mannose 4,6-dehydratase 0.0448569
EEF2 eukaryotic translation elongation factor 2 0.0446746
PTPRK protein tyrosine phosphatase, receptor type, K 0.0445433
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0440299
GOLGB1 golgin B1 0.043967
EXT1 exostosin glycosyltransferase 1 0.0436709
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.0428504
ARHGAP26 Rho GTPase activating protein 26 0.0428114
DSCAM Down syndrome cell adhesion molecule 0.0424639
SPTBN1 spectrin, beta, non-erythrocytic 1 0.041456
TJP1 tight junction protein 1 0.0413787
APLP2 amyloid beta (A4) precursor-like protein 2 0.0407308
ZBTB38 zinc finger and BTB domain containing 38 0.0406217
ADAM19 ADAM metallopeptidase domain 19 0.0403922
CDK13 cyclin-dependent kinase 13 0.0402906
MAN1A1 mannosidase, alpha, class 1A, member 1 0.0399197
CTBP2 C-terminal binding protein 2 0.0394027
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0388322
EXOC4 exocyst complex component 4 0.0387733
MYOF myoferlin 0.0385439
CADPS Ca++-dependent secretion activator 0.0385365
DSPP dentin sialophosphoprotein 0.0381778
SVIL supervillin 0.0379751
RALY RALY heterogeneous nuclear ribonucleoprotein 0.0375135
UBE2H ubiquitin-conjugating enzyme E2H 0.0371804
MYH9 myosin, heavy chain 9, non-muscle 0.0371201
EGFR epidermal growth factor receptor 0.0369968
PCLO piccolo presynaptic cytomatrix protein 0.0369712
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.0361795
CUX1 cut-like homeobox 1 0.0361359
AHNAK AHNAK nucleoprotein 0.0359306
FLNA filamin A, alpha 0.0359127
ETV6 ets variant 6 0.0353319
FTH1 ferritin, heavy polypeptide 1 0.0353306
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 0.0352205
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.035197
NKD1 naked cuticle homolog 1 (Drosophila) 0.0350721
WWC1 WW and C2 domain containing 1 0.034788
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0347855
PATJ PATJ crumbs cell polarity complex component 0.0347697
INTS6 integrator complex subunit 6 0.0345821
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0343407
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.0338741
EZR ezrin 0.0335127
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) 0.0331714
PDLIM5 PDZ and LIM domain 5 0.0329322
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0328651
LIMS1 LIM and senescent cell antigen-like domains 1 0.0328241
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0326906
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.0325605
TRIM2 tripartite motif containing 2 0.0323777
DOCK4 dedicator of cytokinesis 4 0.0322006
PPARD peroxisome proliferator-activated receptor delta 0.032081
MYH14 myosin, heavy chain 14, non-muscle 0.0316637
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0308042
UBAP2 ubiquitin associated protein 2 0.0307636
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.0306124
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0304811
ITGA6 integrin, alpha 6 0.0301922
USP34 ubiquitin specific peptidase 34 0.0301522
TGFA transforming growth factor, alpha 0.0301204
SETX senataxin 0.0300799

decreased expression

Symbol Name Standardized Value
FTL ferritin, light polypeptide -0.181672
PTMA prothymosin, alpha -0.157637
TMSB10 thymosin beta 10 -0.0915758
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0760181
RPL35A ribosomal protein L35a -0.0505231
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0448252
TPT1 tumor protein, translationally-controlled 1 -0.0431211
RPS6 ribosomal protein S6 -0.0393557
RPL23 ribosomal protein L23 -0.0386901
LOC102724023 ES1 protein homolog, mitochondrial -0.0383491
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0372799
RPL12 ribosomal protein L12 -0.0368323
RPLP2 ribosomal protein, large, P2 -0.0363745
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0354899
RPLP1 ribosomal protein, large, P1 -0.035356
RPL28 ribosomal protein L28 -0.034629
RPS21 ribosomal protein S21 -0.0343047
CST3 cystatin C -0.0341166
GSTP1 glutathione S-transferase pi 1 -0.0331799
GARS1 glycyl-tRNA synthetase 1 -0.033004
RPS3 ribosomal protein S3 -0.0325052
EIF1 eukaryotic translation initiation factor 1 -0.0322958
USP3 ubiquitin specific peptidase 3 -0.032249
B2M beta-2-microglobulin -0.0303516
S100A10 S100 calcium binding protein A10 -0.0302763
RPS13 ribosomal protein S13 -0.0298046
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.0298018
RPS25 ribosomal protein S25 -0.0294335
RAD21 RAD21 homolog (S. pombe) -0.0289409
RPL37A ribosomal protein L37a -0.0287563
RPL31 ribosomal protein L31 -0.0281555
RPS19 ribosomal protein S19 -0.0278438
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0276427
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.0275889
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0270024
RPL8 ribosomal protein L8 -0.0269433
NAMPT nicotinamide phosphoribosyltransferase -0.0261339
RPS5 ribosomal protein S5 -0.0255484
RPL19 ribosomal protein L19 -0.0254804
RPL32 ribosomal protein L32 -0.0254575
RPS24 ribosomal protein S24 -0.0251365
ZNF292 zinc finger protein 292 -0.0244776
SEPTIN7 septin 7 -0.0242644
MATR3 matrin 3 -0.0242413
GOLGA4 golgin A4 -0.024209
RBM39 RNA binding motif protein 39 -0.023388
RPL36 ribosomal protein L36 -0.0233623
RPS8 ribosomal protein S8 -0.0232933
ATP5F1E ATP synthase F1 subunit epsilon -0.0232096
S100A6 S100 calcium binding protein A6 -0.0232071
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -0.0229323
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0223371
RPS11 ribosomal protein S11 -0.0223226
S100A9 S100 calcium binding protein A9 -0.0222873
RBM25 RNA binding motif protein 25 -0.0212248
WSB1 WD repeat and SOCS box containing 1 -0.0211827
RNF145 ring finger protein 145 -0.0211512
RPS12 ribosomal protein S12 -0.0208291
RPS29 ribosomal protein S29 -0.0205512
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0203404
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.0202544
RPS15 ribosomal protein S15 -0.020079
RPL36A ribosomal protein L36a -0.0199946
RPL26 ribosomal protein L26 -0.0195995
RPS16 ribosomal protein S16 -0.0195743
TRA2A transformer 2 alpha homolog (Drosophila) -0.0195393
KMT2E lysine (K)-specific methyltransferase 2E -0.0195234
RAB1A RAB1A, member RAS oncogene family -0.0192952
UBE2C ubiquitin-conjugating enzyme E2C -0.019047
UGCG UDP-glucose ceramide glucosyltransferase -0.0186027
RPL18 ribosomal protein L18 -0.0182993
RPS27A ribosomal protein S27a -0.0181429
PERP PERP, TP53 apoptosis effector -0.0179117
CCNL1 cyclin L1 -0.0178875
H3-3B H3.3 histone B -0.017787
RPL34 ribosomal protein L34 -0.0177437
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0174963
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0174219
MYL12B myosin, light chain 12B, regulatory -0.0172325
EPCAM epithelial cell adhesion molecule -0.0171333
UBC ubiquitin C -0.0171047
RPLP0 ribosomal protein, large, P0 -0.0169437
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -0.0168144
FOSL1 FOS-like antigen 1 -0.0167598
RPL37 ribosomal protein L37 -0.0167044
PDIA3 protein disulfide isomerase family A, member 3 -0.0165878
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -0.0165877
FMR1 fragile X mental retardation 1 -0.0165488
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0165304
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.0163596
RPS14 ribosomal protein S14 -0.0162542
RPL27A ribosomal protein L27a -0.0159857
UBE2B ubiquitin-conjugating enzyme E2B -0.0158949
RNF149 ring finger protein 149 -0.0157933
RIOK3 RIO kinase 3 -0.0155655
RTN4 reticulon 4 -0.0153167
RACK1 receptor for activated C kinase 1 -0.0152851
GNAS GNAS complex locus -0.0151187
PLAUR plasminogen activator, urokinase receptor -0.0150174
ADAM17 ADAM metallopeptidase domain 17 -0.0147702