Oleic acid_SW480 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Oleic acid perturbation in SW480 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Oleic acid_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
NKD1 naked cuticle homolog 1 (Drosophila) 0.264105
KRT18 keratin 18, type I 0.173079
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.155356
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.148465
NAV2 neuron navigator 2 0.127646
EEF2 eukaryotic translation elongation factor 2 0.121549
PLEC plectin 0.119963
VCL vinculin 0.117053
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.112596
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.10431
CDK6 cyclin-dependent kinase 6 0.0885129
AHNAK AHNAK nucleoprotein 0.0848148
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0835802
CDH13 cadherin 13 0.08177
AKAP12 A kinase (PRKA) anchor protein 12 0.0806318
CCND1 cyclin D1 0.0794155
INTS6 integrator complex subunit 6 0.0790571
WWOX WW domain containing oxidoreductase 0.0785482
ASPH aspartate beta-hydroxylase 0.0756991
EZR ezrin 0.074152
TNS3 tensin 3 0.0720632
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0716412
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0702881
PTMA prothymosin, alpha 0.0693493
ENO1 enolase 1, (alpha) 0.0660712
MYH9 myosin, heavy chain 9, non-muscle 0.0640625
ANXA2 annexin A2 0.0636178
FTH1 ferritin, heavy polypeptide 1 0.0614214
SPATA13 spermatogenesis associated 13 0.0607673
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0601722
KRT8 keratin 8, type II 0.0588533
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0571551
SYT1 synaptotagmin I 0.0566759
FRMD5 FERM domain containing 5 0.0557113
SEPTIN9 septin 9 0.0556855
LOC102724023 ES1 protein homolog, mitochondrial 0.0548228
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0533088
RAD51B RAD51 paralog B 0.051854
ACTN1 actinin, alpha 1 0.0518466
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0515394
LPP LIM domain containing preferred translocation partner in lipoma 0.0513219
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0512775
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0506176
PDLIM5 PDZ and LIM domain 5 0.0505244
DSPP dentin sialophosphoprotein 0.0488646
MSI2 musashi RNA-binding protein 2 0.0486915
GMDS GDP-mannose 4,6-dehydratase 0.0486249
EXOC4 exocyst complex component 4 0.0485841
ADGRL2 adhesion G protein-coupled receptor L2 0.0485392
PDE4D phosphodiesterase 4D, cAMP-specific 0.0482983
SERINC5 serine incorporator 5 0.0480947
YAP1 Yes-associated protein 1 0.0478733
LOC112694756 uncharaterized LOC112694756 0.0477909
TMEM123 transmembrane protein 123 0.0475553
LMO7 LIM domain 7 0.0468643
VIM vimentin 0.04557
DST dystonin 0.0454713
H1-0 H1.0 linker histone 0.0454459
SKAP1 src kinase associated phosphoprotein 1 0.0453775
SDK1 sidekick cell adhesion molecule 1 0.0453215
FLNA filamin A, alpha 0.0452163
MAML2 mastermind-like 2 (Drosophila) 0.045096
BCL2L1 BCL2-like 1 0.0446134
CUX1 cut-like homeobox 1 0.0433364
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0424018
COBL cordon-bleu WH2 repeat protein 0.0423956
MYO1E myosin IE 0.0423128
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0413202
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0410429
ITGB4 integrin, beta 4 0.0408483
NPAS2 neuronal PAS domain protein 2 0.0407019
ACTN4 actinin, alpha 4 0.0406669
MACF1 microtubule-actin crosslinking factor 1 0.040167
NCEH1 neutral cholesterol ester hydrolase 1 0.0398534
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0397957
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.039714
HDAC4 histone deacetylase 4 0.0395914
SMAD3 SMAD family member 3 0.0393914
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 0.0389676
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.0387152
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0382698
RPS4X ribosomal protein S4, X-linked 0.0378842
MYOF myoferlin 0.0375453
ZBTB20 zinc finger and BTB domain containing 20 0.0372977
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0371841
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0370979
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.0356468
SERBP1 SERPINE1 mRNA binding protein 1 0.0355658
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0352859
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.0351981
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0345408
ITPRID2 ITPR interacting domain containing 2 0.0343701
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0341532
LDHA lactate dehydrogenase A 0.0340971
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0334794
ANO1 anoctamin 1, calcium activated chloride channel 0.0334179
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.0332586
TAS2R14 taste receptor, type 2, member 14 0.0330155
EHBP1 EH domain binding protein 1 0.0329353
FAT1 FAT atypical cadherin 1 0.0328801

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0558681
RBM39 RNA binding motif protein 39 -0.0434936
ESYT2 extended synaptotagmin-like protein 2 -0.0393181
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0325105
GOLGA4 golgin A4 -0.0320845
DIAPH3 diaphanous-related formin 3 -0.0313434
MORF4L2 mortality factor 4 like 2 -0.0310097
ZNF292 zinc finger protein 292 -0.0292853
OXR1 oxidation resistance 1 -0.028525
BRWD3 bromodomain and WD repeat domain containing 3 -0.0277043
RPS3 ribosomal protein S3 -0.0275348
PCBP2 poly(rC) binding protein 2 -0.0260163
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.0258107
GARS1 glycyl-tRNA synthetase 1 -0.02567
PROX1 prospero homeobox 1 -0.0253636
OGA O-GlcNAcase -0.0253333
UBA6 ubiquitin-like modifier activating enzyme 6 -0.025106
EIF1 eukaryotic translation initiation factor 1 -0.0249905
TMSB10 thymosin beta 10 -0.0240684
TXNIP thioredoxin interacting protein -0.0235997
RPS2 ribosomal protein S2 -0.0230426
CCDC82 coiled-coil domain containing 82 -0.022981
MIS18BP1 MIS18 binding protein 1 -0.0227802
ARF4 ADP-ribosylation factor 4 -0.0227134
TMEM41B transmembrane protein 41B -0.0223241
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.0222258
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0221421
KMT2C lysine (K)-specific methyltransferase 2C -0.0217898
SMC4 structural maintenance of chromosomes 4 -0.0217317
RAB6A RAB6A, member RAS oncogene family -0.0214731
RPLP2 ribosomal protein, large, P2 -0.0213931
COG5 component of oligomeric golgi complex 5 -0.0211275
AKAP9 A kinase (PRKA) anchor protein 9 -0.0208806
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0208009
RPL35A ribosomal protein L35a -0.0207834
EXOC1 exocyst complex component 1 -0.0206728
NUP58 nucleoporin 58 -0.0205762
RPS29 ribosomal protein S29 -0.020434
TBC1D23 TBC1 domain family, member 23 -0.0202554
NKTR natural killer cell triggering receptor -0.020199
DDIT4 DNA-damage-inducible transcript 4 -0.0201024
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) -0.0197852
ADAM17 ADAM metallopeptidase domain 17 -0.0197347
ZMYM2 zinc finger, MYM-type 2 -0.0195511
PDE8A phosphodiesterase 8A -0.0193592
WASF2 WAS protein family, member 2 -0.0193189
PTEN phosphatase and tensin homolog -0.0192824
CEMIP2 cell migration inducing hyaluronidase 2 -0.0191948
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0191681
VGLL4 vestigial-like family member 4 -0.0186631
RPL36 ribosomal protein L36 -0.018586
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0182902
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.0181309
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0180888
USP3 ubiquitin specific peptidase 3 -0.0179445
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0178809
MED23 mediator complex subunit 23 -0.0177942
CD46 CD46 molecule, complement regulatory protein -0.0177698
SRP54 signal recognition particle 54kDa -0.0177363
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 -0.0177064
WDFY2 WD repeat and FYVE domain containing 2 -0.0176943
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -0.017653
STARD4 StAR-related lipid transfer (START) domain containing 4 -0.0176424
MTF2 metal response element binding transcription factor 2 -0.0173775
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0172878
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.017066
PDK3 pyruvate dehydrogenase kinase, isozyme 3 -0.0169579
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0169323
RPS19 ribosomal protein S19 -0.0169275
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 -0.0169071
GMCL1 germ cell-less, spermatogenesis associated 1 -0.0168138
TMF1 TATA element modulatory factor 1 -0.0166689
ACBD3 acyl-CoA binding domain containing 3 -0.0166508
KMT2E lysine (K)-specific methyltransferase 2E -0.016583
RPL36A ribosomal protein L36a -0.0163202
FANCL Fanconi anemia, complementation group L -0.0161256
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -0.0160501
WDR45B WD repeat domain 45B -0.0159701
RPL38 ribosomal protein L38 -0.0159431
CEP95 centrosomal protein 95kDa -0.0158535
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.015833
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 -0.015822
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0158181
CEP192 centrosomal protein 192kDa -0.0158053
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit -0.015786
WSB1 WD repeat and SOCS box containing 1 -0.0154806
RNF43 ring finger protein 43 -0.015475
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -0.0154602
RPS12 ribosomal protein S12 -0.0154442
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.0154266
CDK8 cyclin-dependent kinase 8 -0.0153456
MON2 MON2 homolog (S. cerevisiae) -0.015301
XPO1 exportin 1 -0.0152521
GOLT1B golgi transport 1B -0.0152418
RPL26 ribosomal protein L26 -0.0152225
YEATS2 YEATS domain containing 2 -0.0150159
AVL9 AVL9 homolog (S. cerevisiase) -0.0150095
RPL28 ribosomal protein L28 -0.0149994
RPS13 ribosomal protein S13 -0.0148456
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0148265