Oligodendroglioma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A well-differentiated (WHO grade II), diffusely infiltrating neuroglial tumor, typically located in the cerebral hemispheres. It is composed predominantly of cells which morphologically resemble oligodendroglia. The neoplastic cells have rounded homogeneous nuclei and, on paraffin sections, a swollen, clear cytoplasm ('honeycomb' appearance). (Adapted from WHO.)|A relatively slow-growing glioma that is derived from oligodendrocytes and tends to occur in the cerebral hemispheres, thalamus, or lateral ventricle. They may present at any age, but are most frequent in the third to fifth decades, with an earlier incidence peak in the first decade. Histologically, these tumors are encapsulated, relatively avascular, and tend to form cysts and microcalcifications. Neoplastic cells tend to have small round nuclei surrounded by unstained nuclei. The tumors may vary from well-differentiated to highly anaplastic forms. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2052; Adams et al., Principles of Neurology, 6th ed, p655)|A well-differentiated (WHO grade II), diffusely infiltrating neuroglial tumor, typically located in the cerebral hemispheres. It is composed predominantly of cells which morphologically resemble oligodendroglia. The neoplastic cells have rounded homogeneous nuclei and, on paraffin sections, a swollen, clear cytoplasm ('honeycomb' appearance). (Adapted from WHO)|A well-differentiated (WHO grade II), diffusely infiltrating neuroglial tumor, typically located in the cerebral hemispheres. It is composed predominantly of cells which morphologically resemble oligodendroglia. The neoplastic cells have rounded homogeneous nuclei and, on paraffin sections, a swollen, clear cytoplasm ('honeycomb' appearance). (Adapted from WHO.)|A relatively slow-growing glioma that is derived from oligodendrocytes and tends to occur in the cerebral hemispheres, thalamus, or lateral ventricle. They may present at any age, but are most frequent in the third to fifth decades, with an earlier incidence peak in the first decade. Histologically, these tumors are encapsulated, relatively avascular, and tend to form cysts and microcalcifications. Neoplastic cells tend to have small round nuclei surrounded by unstained nuclei. The tumors may vary from well-differentiated to highly anaplastic forms (MeSH).|A well-differentiated (WHO grade II), diffusely infiltrating neuroglial tumor of adults, typically located in the cerebral hemispheres. It is composed predominantly of cells which morphologically resemble oligodendroglia. The neoplastic cells have rounded homogeneous nuclei and, on paraffin sections, a swollen, clear cytoplasm ('honeycomb' appearance). It generally recurs locally, with median post-operative survival times ranging from 3 to 5 years for patients with all histological grades. (Adapted from WHO.) (Experimental Factor Ontology, EFO_0000632)
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Genes

701 genes co-occuring with the disease Oligodendroglioma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 3.842
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 3.572
MGMT O-6-methylguanine-DNA methyltransferase 3.435
ATRX alpha thalassemia/mental retardation syndrome X-linked 3.406
FUBP1 far upstream element (FUSE) binding protein 1 3.124
OLIG2 oligodendrocyte lineage transcription factor 2 3.124
TERT telomerase reverse transcriptase 3.088
TP53 tumor protein p53 2.99
EGFR epidermal growth factor receptor 2.951
CDKN2A cyclin-dependent kinase inhibitor 2A 2.793
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.782
KIAA1549 KIAA1549 2.773
GFAP glial fibrillary acidic protein 2.75
PTEN phosphatase and tensin homolog 2.727
H3-3A H3.3 histone A 2.712
NF1 neurofibromin 1 2.619
NES nestin 2.586
BRAF B-Raf proto-oncogene, serine/threonine kinase 2.578
CIC capicua transcriptional repressor 2.526
SYP synaptophysin 2.475
H3-3B H3.3 histone B 2.455
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.376
PROM1 prominin 1 2.354
OLIG1 oligodendrocyte transcription factor 1 2.34
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 2.314
EGF epidermal growth factor 2.302
SOX2 SRY (sex determining region Y)-box 2 2.277
CDK4 cyclin-dependent kinase 4 2.277
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.269
H3C2 H3 clustered histone 2 2.267
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.264
PDGFB platelet-derived growth factor beta polypeptide 2.263
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 2.238
FGFR1 fibroblast growth factor receptor 1 2.213
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 2.202
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 2.192
H3C12 H3 clustered histone 12 2.19
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 2.19
EMP3 epithelial membrane protein 3 2.176
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 2.173
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 2.155
MTOR mechanistic target of rapamycin (serine/threonine kinase) 2.154
PHLDB1 pleckstrin homology-like domain, family B, member 1 2.147
SHH sonic hedgehog 2.118
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 2.098
MYB v-myb avian myeloblastosis viral oncogene homolog 2.094
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.088
FGF2 fibroblast growth factor 2 (basic) 2.085
DAXX death-domain associated protein 2.067
TACC3 transforming, acidic coiled-coil containing protein 3 2.047
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 2.044
PDGFRB platelet-derived growth factor receptor, beta polypeptide 2.043
NOTCH1 notch 1 2.037
TACC1 transforming, acidic coiled-coil containing protein 1 2.025
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 2.025
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.02
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.009
ENO2 enolase 2 (gamma, neuronal) 1.99
CD274 CD274 molecule 1.978
H3C3 H3 clustered histone 3 1.976
FGFR3 fibroblast growth factor receptor 3 1.975
CD34 CD34 molecule 1.975
MDM4 MDM4, p53 regulator 1.965
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.964
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.954
CDK6 cyclin-dependent kinase 6 1.953
ERBB2 erb-b2 receptor tyrosine kinase 2 1.95
CD8A CD8a molecule 1.95
PDGFA platelet-derived growth factor alpha polypeptide 1.946
CD44 CD44 molecule (Indian blood group) 1.945
CCND1 cyclin D1 1.938
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.936
H3C13 H3 clustered histone 13 1.934
SOX10 SRY (sex determining region Y)-box 10 1.934
PXDNL peroxidasin-like 1.933
PXDN peroxidasin 1.933
H3-5 H3.5 histone 1.931
TGFB1 transforming growth factor, beta 1 1.924
H3-4 H3.4 histone, cluster member 1.922
FAM131B family with sequence similarity 131, member B 1.919
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1.917
IL13RA2 interleukin 13 receptor, alpha 2 1.915
ACTB actin, beta 1.911
NF2 neurofibromin 2 (merlin) 1.91
AJAP1 adherens junctions associated protein 1 1.903
INA internexin neuronal intermediate filament protein, alpha 1.898
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.878
CSPG4 chondroitin sulfate proteoglycan 4 1.876
BICRA BRD4 interacting chromatin remodeling complex associated protein 1.867
CD4 CD4 molecule 1.866
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.853
BCAN brevican 1.847
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.843
MN1 meningioma (disrupted in balanced translocation) 1 1.843
MMUT methylmalonyl-CoA mutase 1.84
RTEL1 regulator of telomere elongation helicase 1 1.825
FOXR2 forkhead box R2 1.825
AGO2 argonaute RISC catalytic component 2 1.824
ETV1 ets variant 1 1.822
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 1.82
S100B S100 calcium binding protein B 1.817
MET MET proto-oncogene, receptor tyrosine kinase 1.816
ETV5 ets variant 5 1.813
BMI1 BMI1 proto-oncogene, polycomb ring finger 1.805
TCF12 transcription factor 12 1.8
NKX2-2 NK2 homeobox 2 1.796
ETV4 ets variant 4 1.794
MBP myelin basic protein 1.794
MSH6 mutS homolog 6 1.793
COMMD3-BMI1 COMMD3-BMI1 readthrough 1.791
MMP2 matrix metallopeptidase 2 1.791
AIF1 allograft inflammatory factor 1 1.79
ASCL1 achaete-scute family bHLH transcription factor 1 1.782
KRAS Kirsten rat sarcoma viral oncogene homolog 1.781
BCL2 B-cell CLL/lymphoma 2 1.772
FGFR2 fibroblast growth factor receptor 2 1.769
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.763
MMP9 matrix metallopeptidase 9 1.76
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.756
LEUTX leucine twenty homeobox 1.755
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.753
PECAM1 platelet/endothelial cell adhesion molecule 1 1.748
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.748
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.747
NANOG Nanog homeobox 1.733
NOTCH2 notch 2 1.717
QKI QKI, KH domain containing, RNA binding 1.715
MSI1 musashi RNA-binding protein 1 1.714
ZNF296 zinc finger protein 296 1.711
NLGN3 neuroligin 3 1.708
D2HGDH D-2-hydroxyglutarate dehydrogenase 1.703
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.701
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.698
DMBT1 deleted in malignant brain tumors 1 1.695
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.683
POU3F2 POU class 3 homeobox 2 1.677
H3C6 H3 clustered histone 6 1.671
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 1.67
PTN pleiotrophin 1.664
FABP7 fatty acid binding protein 7, brain 1.662
POU5F1 POU class 5 homeobox 1 1.662
IFNG interferon, gamma 1.661
BIRC5 baculoviral IAP repeat containing 5 1.659
PCNA proliferating cell nuclear antigen 1.659
TTYH1 tweety family member 1 1.658
DUX4 double homeobox 4 1.656
TET2 tet methylcytosine dioxygenase 2 1.655
HAVCR2 hepatitis A virus cellular receptor 2 1.655
KDR kinase insert domain receptor 1.652
L1CAM L1 cell adhesion molecule 1.652
EZHIP EZH inhibitory protein 1.652
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 1.646
ATM ATM serine/threonine kinase 1.642
MLH1 mutL homolog 1 1.64
TNF tumor necrosis factor 1.637
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 1.637
MAP2 microtubule-associated protein 2 1.635
FN1 fibronectin 1 1.629
EPHA2 EPH receptor A2 1.624
MSH2 mutS homolog 2 1.623
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.621
CD276 CD276 molecule 1.618
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 1.615
SOX8 SRY (sex determining region Y)-box 8 1.614
CA9 carbonic anhydrase IX 1.612
PARP1 poly (ADP-ribose) polymerase 1 1.61
ALK anaplastic lymphoma receptor tyrosine kinase 1.605
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.604
NFIA nuclear factor I/A 1.603
PDCD1 programmed cell death 1 1.599
PCDHGA11 protocadherin gamma subfamily A, 11 1.597
CD163 CD163 molecule 1.597
FGF3 fibroblast growth factor 3 1.594
RNF130 ring finger protein 130 1.594
DLL3 delta-like 3 (Drosophila) 1.593
YAP1 Yes-associated protein 1 1.593
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.592
FGF6 fibroblast growth factor 6 1.591
CSF1R colony stimulating factor 1 receptor 1.588
ANXA5 annexin A5 1.587
FGF17 fibroblast growth factor 17 1.586
GLI1 GLI family zinc finger 1 1.586
CXCR4 chemokine (C-X-C motif) receptor 4 1.585
IDO1 indoleamine 2,3-dioxygenase 1 1.584
FGF20 fibroblast growth factor 20 1.582
FGF5 fibroblast growth factor 5 1.58
FGF10 fibroblast growth factor 10 1.58
ACVR1 activin A receptor, type I 1.58
FGF22 fibroblast growth factor 22 1.579
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.579
FGF16 fibroblast growth factor 16 1.577
FGF9 fibroblast growth factor 9 1.577
LDHA lactate dehydrogenase A 1.576
FGF18 fibroblast growth factor 18 1.573
FGF8 fibroblast growth factor 8 (androgen-induced) 1.571
ALB albumin 1.566
FGF4 fibroblast growth factor 4 1.564
TCHP trichoplein, keratin filament binding 1.563
IL6 interleukin 6 1.563
PTCH1 patched 1 1.562
HRAS Harvey rat sarcoma viral oncogene homolog 1.561
CD68 CD68 molecule 1.558
PATZ1 POZ (BTB) and AT hook containing zinc finger 1 1.557
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.556
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 1.552
EPAS1 endothelial PAS domain protein 1 1.551
SALL2 spalt-like transcription factor 2 1.548
SOX9 SRY (sex determining region Y)-box 9 1.548
LAG3 lymphocyte-activation gene 3 1.547
AOC2 amine oxidase, copper containing 2 (retina-specific) 1.547
PTPRC protein tyrosine phosphatase, receptor type, C 1.546
SETD2 SET domain containing 2 1.544
FGF7 fibroblast growth factor 7 1.539
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.536
SZRD1 SUZ RNA binding domain containing 1 1.534
MAPK3 mitogen-activated protein kinase 3 1.532
CCND2 cyclin D2 1.532
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 1.529
MAP2K1 mitogen-activated protein kinase kinase 1 1.528
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.527
BCL2L1 BCL2-like 1 1.527
JUN jun proto-oncogene 1.52
TP73 tumor protein p73 1.519
RB1 retinoblastoma 1 1.517
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 1.513
IL10 interleukin 10 1.508
CXCL12 chemokine (C-X-C motif) ligand 12 1.507
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 1.504
CNOT1 CCR4-NOT transcription complex, subunit 1 1.504
BAX BCL2-associated X protein 1.501
DCX doublecortin 1.498
ETDB embryonic testis differentiation homolog B 1.496
NCAM1 neural cell adhesion molecule 1 1.491
SHTN1 shootin 1 1.486
SYT1 synaptotagmin I 1.486
TUBB3 tubulin, beta 3 class III 1.482
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.478
HDAC9 histone deacetylase 9 1.477
BRCA1 breast cancer 1, early onset 1.474
GALC galactosylceramidase 1.472
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 1.469
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.463
E2F1 E2F transcription factor 1 1.462
TSC2 tuberous sclerosis 2 1.461
BCAT1 branched chain amino-acid transaminase 1, cytosolic 1.461
CCL2 chemokine (C-C motif) ligand 2 1.461
CDK2 cyclin-dependent kinase 2 1.46
ZNF606-AS1 ZNF606 antisense RNA 1 1.459
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 1.458
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.456
PLAUR plasminogen activator, urokinase receptor 1.453
L2HGDH L-2-hydroxyglutarate dehydrogenase 1.452
FOXM1 forkhead box M1 1.451
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.45
TGFB2 transforming growth factor, beta 2 1.447
FUBP3 far upstream element (FUSE) binding protein 3 1.444
SEPTIN14 septin 14 1.444
KLF4 Kruppel-like factor 4 (gut) 1.443
UBP1 upstream binding protein 1 (LBP-1a) 1.441
FGF13 fibroblast growth factor 13 1.438
IGF1R insulin-like growth factor 1 receptor 1.437
CHEK2 checkpoint kinase 2 1.431
SNAI1 snail family zinc finger 1 1.43
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 1.426
ITK IL2-inducible T-cell kinase 1.424
CSF1 colony stimulating factor 1 (macrophage) 1.424
ERBB3 erb-b2 receptor tyrosine kinase 3 1.422
IL1B interleukin 1, beta 1.42
PDCD1LG2 programmed cell death 1 ligand 2 1.418
VIM vimentin 1.418
FLT1 fms-related tyrosine kinase 1 1.416
KDM4A lysine (K)-specific demethylase 4A 1.413
ISL2 ISL LIM homeobox 2 1.412
CXCL8 chemokine (C-X-C motif) ligand 8 1.412
MKI67 marker of proliferation Ki-67 1.411
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.41
GJA1 gap junction protein, alpha 1, 43kDa 1.409
ETNPPL ethanolamine-phosphate phospho-lyase 1.405
ESR1 estrogen receptor 1 1.404
EWSR1 EWS RNA-binding protein 1 1.404
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.401
CD86 CD86 molecule 1.398
TK2 thymidine kinase 2, mitochondrial 1.398
IL2 interleukin 2 1.396
WNK2 WNK lysine deficient protein kinase 2 1.395
CD99 CD99 molecule 1.395
ZEB1 zinc finger E-box binding homeobox 1 1.393
SOX4 SRY (sex determining region Y)-box 4 1.388
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.387
SMOC1 SPARC related modular calcium binding 1 1.38
ITGA6 integrin, alpha 6 1.38
RHOA ras homolog family member A 1.379
IGF1 insulin-like growth factor 1 (somatomedin C) 1.377
MTDH metadherin 1.376
ERBB4 erb-b2 receptor tyrosine kinase 4 1.375
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 1.367
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.366
CTNNA3 catenin (cadherin-associated protein), alpha 3 1.364
TIMP3 TIMP metallopeptidase inhibitor 3 1.363
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.363
CDC42 cell division cycle 42 1.363
CHEK1 checkpoint kinase 1 1.363
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 1.362
AURKA aurora kinase A 1.362
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 1.361
ATXN1L ataxin 1-like 1.361
CSMD2 CUB and Sushi multiple domains 2 1.36
STAT1 signal transducer and activator of transcription 1, 91kDa 1.355
WT1 Wilms tumor 1 1.355
CCNL2 cyclin L2 1.354
NEFL neurofilament, light polypeptide 1.351
EP300 E1A binding protein p300 1.35
FOXP3 forkhead box P3 1.349
LGALS3 lectin, galactoside-binding, soluble, 3 1.348
PKM pyruvate kinase, muscle 1.348
GABPA GA binding protein transcription factor, alpha subunit 60kDa 1.348
SOX11 SRY (sex determining region Y)-box 11 1.346
TTN titin 1.343
RET ret proto-oncogene 1.343
CCK cholecystokinin 1.343
TIMP1 TIMP metallopeptidase inhibitor 1 1.341
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.341
JAG1 jagged 1 1.34
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 1.34
RTN4 reticulon 4 1.34
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.338
PDPN podoplanin 1.337
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.336
GSK3B glycogen synthase kinase 3 beta 1.336
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.335
ETFA electron-transfer-flavoprotein, alpha polypeptide 1.335
HES5 hes family bHLH transcription factor 5 1.334
PAX6 paired box 6 1.332
PRKCA protein kinase C, alpha 1.331
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 1.331
CD99L2 CD99 molecule-like 2 1.33
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 1.329
MAGED4B melanoma antigen family D4B 1.329
TSPO translocator protein (18kDa) 1.328
POLE polymerase (DNA directed), epsilon, catalytic subunit 1.327
BMP4 bone morphogenetic protein 4 1.326
BDNF brain-derived neurotrophic factor 1.326
PLP1 proteolipid protein 1 1.326
AKT3 v-akt murine thymoma viral oncogene homolog 3 1.323
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 1.323
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 1.321
MSR1 macrophage scavenger receptor 1 1.319
NFIB nuclear factor I/B 1.319
SOX6 SRY (sex determining region Y)-box 6 1.317
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.317
CCNA2 cyclin A2 1.316
CD80 CD80 molecule 1.314
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.312
CDKN3 cyclin-dependent kinase inhibitor 3 1.31
DLL1 delta-like 1 (Drosophila) 1.307
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.305
CREB1 cAMP responsive element binding protein 1 1.304
MOBP myelin-associated oligodendrocyte basic protein 1.304
IFNB1 interferon, beta 1, fibroblast 1.297
STMN1 stathmin 1 1.294
THBS1 thrombospondin 1 1.293
SNAI2 snail family zinc finger 2 1.292
LOX lysyl oxidase 1.292
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.292
SEC61G Sec61 gamma subunit 1.291
NAPRT nicotinate phosphoribosyltransferase 1.29
ARHGAP35 Rho GTPase activating protein 35 1.29
GNG5 guanine nucleotide binding protein (G protein), gamma 5 1.289
HNF4A hepatocyte nuclear factor 4, alpha 1.289
FOS FBJ murine osteosarcoma viral oncogene homolog 1.288
CAMTA1 calmodulin binding transcription activator 1 1.288
GLS2 glutaminase 2 (liver, mitochondrial) 1.286
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.285
TRIM3 tripartite motif containing 3 1.283
KDM6A lysine (K)-specific demethylase 6A 1.283
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 1.282
PHGDH phosphoglycerate dehydrogenase 1.28
CREBBP CREB binding protein 1.279
WEE1 WEE1 G2 checkpoint kinase 1.278
HGFAC HGF activator 1.278
BEX2 brain expressed X-linked 2 1.276
GLI2 GLI family zinc finger 2 1.274
TMEM119 transmembrane protein 119 1.274
RAD51 RAD51 recombinase 1.272
CDK1 cyclin-dependent kinase 1 1.27
PCDHGA1 protocadherin gamma subfamily A, 1 1.27
MTAP methylthioadenosine phosphorylase 1.269
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) 1.269
MELK maternal embryonic leucine zipper kinase 1.268
SUFU suppressor of fused homolog (Drosophila) 1.268
GLUL glutamate-ammonia ligase 1.267
BRCA2 breast cancer 2, early onset 1.265
DAPK1 death-associated protein kinase 1 1.265
SLC16A4 solute carrier family 16, member 4 1.264
MAGED4 melanoma antigen family D4 1.263
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.263
CCNB1 cyclin B1 1.26
TIGIT T cell immunoreceptor with Ig and ITIM domains 1.259
GLIPR1 GLI pathogenesis-related 1 1.257
TOP2A topoisomerase (DNA) II alpha 170kDa 1.255
CCNA1 cyclin A1 1.255
PLK1 polo-like kinase 1 1.255
TET1 tet methylcytosine dioxygenase 1 1.254
PMEL premelanosome protein 1.254
ATAD2B ATPase family, AAA domain containing 2B 1.251
ARID1A AT rich interactive domain 1A (SWI-like) 1.249
ADAM10 ADAM metallopeptidase domain 10 1.247
MAGEA1 melanoma antigen family A1 1.247
GLS glutaminase 1.246
TWIST1 twist family bHLH transcription factor 1 1.245
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.242
CXCL10 chemokine (C-X-C motif) ligand 10 1.24
IQGAP1 IQ motif containing GTPase activating protein 1 1.24
FH fumarate hydratase 1.24
INS insulin 1.239
SLITRK4 SLIT and NTRK-like family, member 4 1.237
ALKBH2 alkB, alkylation repair homolog 2 (E. coli) 1.236
CA11 carbonic anhydrase XI 1.235
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.235
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 1.234
SRSF1 serine/arginine-rich splicing factor 1 1.234
BRD4 bromodomain containing 4 1.233
CD24 CD24 molecule 1.23
CD47 CD47 molecule 1.23
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 1.229
ADGRL4 adhesion G protein-coupled receptor L4 1.229
ATXN1 ataxin 1 1.228
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 1.228
PNMA8A PNMA family member 8A 1.226
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1.226
TGFA transforming growth factor, alpha 1.226
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 1.225
IGF2 insulin-like growth factor 2 1.223
JAK2 Janus kinase 2 1.222
FGF1 fibroblast growth factor 1 (acidic) 1.221
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.22
NECAP2 NECAP endocytosis associated 2 1.219
PLAU plasminogen activator, urokinase 1.216
FOXG1 forkhead box G1 1.215
DICER1 dicer 1, ribonuclease type III 1.214
MAG myelin associated glycoprotein 1.21
POTEF POTE ankyrin domain family, member F 1.208
HDAC1 histone deacetylase 1 1.208
NGF nerve growth factor (beta polypeptide) 1.206
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.205
MAMLD1 mastermind-like domain containing 1 1.205
DES desmin 1.205
CENPK centromere protein K 1.202
CTCF CCCTC-binding factor (zinc finger protein) 1.202
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 1.202
SLC35G2 solute carrier family 35, member G2 1.201
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.201
PVR poliovirus receptor 1.201
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 1.198
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.198
TFRC transferrin receptor 1.196
WNT5A wingless-type MMTV integration site family, member 5A 1.194
KDM4C lysine (K)-specific demethylase 4C 1.193
GRB2 growth factor receptor-bound protein 2 1.193
CAV1 caveolin 1, caveolae protein, 22kDa 1.193
STAT5B signal transducer and activator of transcription 5B 1.192
GOPC golgi-associated PDZ and coiled-coil motif containing 1.192
CYCS cytochrome c, somatic 1.192
PRKDC protein kinase, DNA-activated, catalytic polypeptide 1.192
IL4 interleukin 4 1.191
BCL2L12 BCL2-like 12 (proline rich) 1.19
ANGPT2 angiopoietin 2 1.189
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.186
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.186
CD70 CD70 molecule 1.185
ASPA aspartoacylase 1.185
PTK2 protein tyrosine kinase 2 1.183
IL13 interleukin 13 1.181
HLA-A major histocompatibility complex, class I, A 1.18
MAPK1 mitogen-activated protein kinase 1 1.179
TEK TEK tyrosine kinase, endothelial 1.178
STMN3 stathmin-like 3 1.177
SOWAHA sosondowah ankyrin repeat domain family member A 1.176
GPNMB glycoprotein (transmembrane) nmb 1.176
FASLG Fas ligand (TNF superfamily, member 6) 1.173
ETV6 ets variant 6 1.172
BCR breakpoint cluster region 1.168
SSBP2 single-stranded DNA binding protein 2 1.167
SOX13 SRY (sex determining region Y)-box 13 1.166
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 1.166
BCAS1 breast carcinoma amplified sequence 1 1.165
ATOH1 atonal homolog 1 (Drosophila) 1.165
RHOC ras homolog family member C 1.162
CLCN6 chloride channel, voltage-sensitive 6 1.162
SSTR2 somatostatin receptor 2 1.16
BECN1 beclin 1, autophagy related 1.16
MOG myelin oligodendrocyte glycoprotein 1.16
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.16
OR5AC2 olfactory receptor, family 5, subfamily AC, member 2 1.159
OLIG3 oligodendrocyte transcription factor 3 1.158
C2ORF80 chromosome 2 open reading frame 80 1.158
PTBP1 polypyrimidine tract binding protein 1 1.157
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.157
KDM1A lysine (K)-specific demethylase 1A 1.157
NOP53 NOP53 ribosome biogenesis factor 1.157
AXL AXL receptor tyrosine kinase 1.155
SRY sex determining region Y 1.153
ANXA1 annexin A1 1.15
CHGA chromogranin A 1.15
CLIC1 chloride intracellular channel 1 1.149
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.149
REST RE1-silencing transcription factor 1.147
IL1A interleukin 1, alpha 1.146
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 1.146
P2RY12 purinergic receptor P2Y, G-protein coupled, 12 1.146
NEU2 sialidase 2 (cytosolic sialidase) 1.143
PGR progesterone receptor 1.143
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 1.143
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.139
ANXA2 annexin A2 1.138
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.135
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.134
STAT5A signal transducer and activator of transcription 5A 1.133
VCL vinculin 1.132
SPP1 secreted phosphoprotein 1 1.13
LGALS9 lectin, galactoside-binding, soluble, 9 1.128
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 1.127
SRI sorcin 1.127
S100A4 S100 calcium binding protein A4 1.126
ARG1 arginase 1 1.125
POLD2 polymerase (DNA directed), delta 2, accessory subunit 1.125
CLDN5 claudin 5 1.124
EPHB2 EPH receptor B2 1.123
SOX5 SRY (sex determining region Y)-box 5 1.122
CD28 CD28 molecule 1.12
IDO2 indoleamine 2,3-dioxygenase 2 1.118
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 1.117
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 1.116
CCR2 chemokine (C-C motif) receptor 2 1.115
EPHA3 EPH receptor A3 1.115
H3C14 H3 clustered histone 14 1.114
CDC20 cell division cycle 20 1.114
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 1.113
NOTCH3 notch 3 1.113
CCL5 chemokine (C-C motif) ligand 5 1.111
PDGFC platelet derived growth factor C 1.111
POSTN periostin, osteoblast specific factor 1.11
GABPB1 GA binding protein transcription factor, beta subunit 1 1.11
RUNX1 runt-related transcription factor 1 1.11
NKX6-2 NK6 homeobox 2 1.107
BMP2 bone morphogenetic protein 2 1.107
MCL1 myeloid cell leukemia 1 1.106
FLT3 fms-related tyrosine kinase 3 1.106
GPR17 G protein-coupled receptor 17 1.106
DNAH8 dynein, axonemal, heavy chain 8 1.105
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 1.105
MMP24 matrix metallopeptidase 24 (membrane-inserted) 1.103
PLCG1 phospholipase C, gamma 1 1.103
KHSRP KH-type splicing regulatory protein 1.102
SUZ12 SUZ12 polycomb repressive complex 2 subunit 1.101
NAMPT nicotinamide phosphoribosyltransferase 1.097
NEUROG2 neurogenin 2 1.097
SIRT1 sirtuin 1 1.096
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 1.096
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 1.095
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 1.095
BEX1 brain expressed, X-linked 1 1.095
MRC1 mannose receptor, C type 1 1.093
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.093
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 1.09
CD40 CD40 molecule, TNF receptor superfamily member 5 1.09
NGFR nerve growth factor receptor 1.087
SMAD4 SMAD family member 4 1.085
HK2 hexokinase 2 1.085
CD19 CD19 molecule 1.084
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.08
HSPB1 heat shock 27kDa protein 1 1.079
EIF4E eukaryotic translation initiation factor 4E 1.078
DRG2 developmentally regulated GTP binding protein 2 1.078
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.078
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 1.078
SOS1 son of sevenless homolog 1 (Drosophila) 1.077
RASA1 RAS p21 protein activator (GTPase activating protein) 1 1.077
SMC4 structural maintenance of chromosomes 4 1.076
ANXA7 annexin A7 1.075
TRIM67 tripartite motif containing 67 1.075
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.074
BSG basigin (Ok blood group) 1.074
EZR ezrin 1.074
AURKB aurora kinase B 1.072
TGFBI transforming growth factor, beta-induced, 68kDa 1.072
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.071
EPHA1 EPH receptor A1 1.071
H2BC21 H2B clustered histone 21 1.07
GDNF glial cell derived neurotrophic factor 1.07
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.07
TK1 thymidine kinase 1, soluble 1.07
HIP1R huntingtin interacting protein 1 related 1.069
C20ORF204 chromosome 20 open reading frame 204 1.069
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 1.069
EIF1AD eukaryotic translation initiation factor 1A domain containing 1.069
S100A10 S100 calcium binding protein A10 1.068
EGR1 early growth response 1 1.068
CNTF ciliary neurotrophic factor 1.067
E2F2 E2F transcription factor 2 1.067
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.067
CA2 carbonic anhydrase II 1.066
TJP1 tight junction protein 1 1.064
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.063
GSX2 GS homeobox 2 1.063
RICTOR RPTOR independent companion of MTOR, complex 2 1.063
ALDOC aldolase C, fructose-bisphosphate 1.062
CHKA choline kinase alpha 1.061
ATP7A ATPase, Cu++ transporting, alpha polypeptide 1.06
ARNT aryl hydrocarbon receptor nuclear translocator 1.06
CNTN2 contactin 2 (axonal) 1.06
LATS2 large tumor suppressor kinase 2 1.058
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 1.057
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.057
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.056
H2AC18 H2A clustered histone 18 1.056
HSPA4 heat shock 70kDa protein 4 1.056
CXCL9 chemokine (C-X-C motif) ligand 9 1.056
KMT2A lysine (K)-specific methyltransferase 2A 1.055
YY1 YY1 transcription factor 1.054
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.052
HDAC2 histone deacetylase 2 1.052
PXN paxillin 1.051
FUS FUS RNA binding protein 1.051
SMO smoothened, frizzled class receptor 1.05
LIG4 ligase IV, DNA, ATP-dependent 1.05
NUMBL numb homolog (Drosophila)-like 1.05
CA12 carbonic anhydrase XII 1.049
NRCAM neuronal cell adhesion molecule 1.049
CCNE1 cyclin E1 1.048
ALKBH5 AlkB family member 5, RNA demethylase 1.048
SPRY4 sprouty homolog 4 (Drosophila) 1.047
IFNA1 interferon, alpha 1 1.047
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.044
LEF1 lymphoid enhancer-binding factor 1 1.044
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.042
NT5E 5'-nucleotidase, ecto (CD73) 1.041
SIRT2 sirtuin 2 1.04
APOE apolipoprotein E 1.04
BCORL1 BCL6 corepressor-like 1 1.038
GLUD2 glutamate dehydrogenase 2 1.036
HLA-DRA major histocompatibility complex, class II, DR alpha 1.036
ENG endoglin 1.036
TBP TATA box binding protein 1.034
DIRAS3 DIRAS family, GTP-binding RAS-like 3 1.031
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 1.03
CD3G CD3g molecule, gamma (CD3-TCR complex) 1.03
PC pyruvate carboxylase 1.029
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 1.028
NUMB numb homolog (Drosophila) 1.028
SMAD2 SMAD family member 2 1.028
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 1.027
ACSS2 acyl-CoA synthetase short-chain family member 2 1.026
PRMT5 protein arginine methyltransferase 5 1.026
RCOR3 REST corepressor 3 1.025
PRDX1 peroxiredoxin 1 1.025
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.025
SOX17 SRY (sex determining region Y)-box 17 1.025
SH3GL2 SH3-domain GRB2-like 2 1.025
TGIF1 TGFB-induced factor homeobox 1 1.024
DUSP4 dual specificity phosphatase 4 1.024
KAT2B K(lysine) acetyltransferase 2B 1.024
MDK midkine (neurite growth-promoting factor 2) 1.023
EFNB2 ephrin-B2 1.023
MYT1L myelin transcription factor 1-like 1.02
FOXO1 forkhead box O1 1.019
CD200 CD200 molecule 1.019
TTBK2 tau tubulin kinase 2 1.018
PDS5B PDS5 cohesin associated factor B 1.016
GAP43 growth associated protein 43 1.015
HMGA2 high mobility group AT-hook 2 1.015
ENO1 enolase 1, (alpha) 1.014
PGK1 phosphoglycerate kinase 1 1.014
CD63 CD63 molecule 1.014
SPTA1 spectrin, alpha, erythrocytic 1 1.014
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.013
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.013
SP1 Sp1 transcription factor 1.012
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.011
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 1.01
ACLY ATP citrate lyase 1.01
SNCAIP synuclein, alpha interacting protein 1.009
HOXA9 homeobox A9 1.008
H2AC20 H2A clustered histone 20 1.008
MLH3 mutL homolog 3 1.007
CCL22 chemokine (C-C motif) ligand 22 1.007
MYO1F myosin IF 1.007
RUNX3 runt-related transcription factor 3 1.007
THY1 Thy-1 cell surface antigen 1.006
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 1.006
SLITRK5 SLIT and NTRK-like family, member 5 1.005
CTSB cathepsin B 1.004
FYN FYN proto-oncogene, Src family tyrosine kinase 1.003
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 1.003
VEGFC vascular endothelial growth factor C 1.003
VTN vitronectin 1.003
LIN28A lin-28 homolog A (C. elegans) 1.001
HES6 hes family bHLH transcription factor 6 1.0
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.0
POU3F3 POU class 3 homeobox 3 1.0
SMAD3 SMAD family member 3 1.0