| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Omeprazole (sodium)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.0971119 |
| TMEM41B | transmembrane protein 41B | 0.0420505 |
| TXNRD1 | thioredoxin reductase 1 | 0.0308574 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0295319 |
| OXR1 | oxidation resistance 1 | 0.0270076 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0252479 |
| KIF5B | kinesin family member 5B | 0.0247582 |
| MKI67 | marker of proliferation Ki-67 | 0.0221627 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0217282 |
| MTAP | methylthioadenosine phosphorylase | 0.0203373 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0194672 |
| PGK1 | phosphoglycerate kinase 1 | 0.0183344 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0169988 |
| THOC2 | THO complex 2 | 0.0168489 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0163485 |
| CEP70 | centrosomal protein 70kDa | 0.0161252 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.0159766 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0159712 |
| SLC49A4 | solute carrier family 49 member 4 | 0.0158416 |
| FTL | ferritin, light polypeptide | 0.0152035 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0150555 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0150506 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0149432 |
| CCNL1 | cyclin L1 | 0.0145298 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.014241 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.0142247 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0138938 |
| PEX13 | peroxisomal biogenesis factor 13 | 0.013776 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | 0.0134102 |
| KLC1 | kinesin light chain 1 | 0.0131354 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0127902 |
| NKTR | natural killer cell triggering receptor | 0.0124078 |
| NIPSNAP2 | nipsnap homolog 2 | 0.012181 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0120549 |
| AXIN2 | axin 2 | 0.0120161 |
| TMEM123 | transmembrane protein 123 | 0.0119863 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0118021 |
| PRKCI | protein kinase C, iota | 0.0115973 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0115743 |
| PEG10 | paternally expressed 10 | 0.0114988 |
| NDC80 | NDC80 kinetochore complex component | 0.0114494 |
| EPS15 | epidermal growth factor receptor pathway substrate 15 | 0.0114026 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.0113092 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0112259 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0112085 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0109661 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0109118 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.010883 |
| PFN1 | profilin 1 | 0.0108711 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0108092 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0108032 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 | 0.0107912 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | 0.0107232 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | 0.0107188 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0106934 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0105062 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0104843 |
| VCL | vinculin | 0.0104427 |
| ZBTB41 | zinc finger and BTB domain containing 41 | 0.0103282 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0103117 |
| CCDC88A | coiled-coil domain containing 88A | 0.0102192 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0101165 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0100311 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.00962405 |
| KLHL24 | kelch-like family member 24 | 0.00959922 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.00958064 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.00952711 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.00951775 |
| RPS6 | ribosomal protein S6 | 0.00939914 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.00936476 |
| SP3 | Sp3 transcription factor | 0.00934224 |
| TMEM47 | transmembrane protein 47 | 0.00930924 |
| CCNG1 | cyclin G1 | 0.0092468 |
| LONRF1 | LON peptidase N-terminal domain and ring finger 1 | 0.00922838 |
| CCN2 | cellular communication network factor 2 | 0.00921522 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0091812 |
| ATN1 | atrophin 1 | 0.00910181 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.00909957 |
| TBK1 | TANK-binding kinase 1 | 0.00907161 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0090715 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.00905389 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00905378 |
| RNF13 | ring finger protein 13 | 0.0090385 |
| KIF18B | kinesin family member 18B | 0.00900299 |
| CISD1 | CDGSH iron sulfur domain 1 | 0.00895795 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein | 0.00893004 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.00892027 |
| ANKRD12 | ankyrin repeat domain 12 | 0.00886121 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.00885796 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.00876973 |
| ETNK1 | ethanolamine kinase 1 | 0.00873958 |
| PRR11 | proline rich 11 | 0.00866577 |
| DDHD1 | DDHD domain containing 1 | 0.0086549 |
| FBXO22 | F-box protein 22 | 0.00845342 |
| RBL2 | retinoblastoma-like 2 | 0.00842015 |
| TMEM167A | transmembrane protein 167A | 0.00830169 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.00827357 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.00823051 |
| UBE3A | ubiquitin protein ligase E3A | 0.00822601 |
| ERLEC1 | endoplasmic reticulum lectin 1 | 0.00819558 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.157991 |
| NLGN1 | neuroligin 1 | -0.147543 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.119155 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.103546 |
| HMGA2 | high mobility group AT-hook 2 | -0.0892978 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0789146 |
| PCDH7 | protocadherin 7 | -0.0761597 |
| VIM | vimentin | -0.0743706 |
| PCBP2 | poly(rC) binding protein 2 | -0.0732936 |
| TMSB10 | thymosin beta 10 | -0.0683229 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0644445 |
| AHNAK | AHNAK nucleoprotein | -0.0601773 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0554032 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0548135 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0542583 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.053626 |
| CANX | calnexin | -0.0530627 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0523376 |
| ASPH | aspartate beta-hydroxylase | -0.0522451 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0509185 |
| NHSL1 | NHS-like 1 | -0.0507469 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0505257 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0504572 |
| RPS27A | ribosomal protein S27a | -0.0493045 |
| YAP1 | Yes-associated protein 1 | -0.0489181 |
| UBC | ubiquitin C | -0.0488968 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0485994 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0481519 |
| ADIPOR2 | adiponectin receptor 2 | -0.0476243 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0475184 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0468017 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0458448 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0455186 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0451145 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0435099 |
| EHBP1 | EH domain binding protein 1 | -0.0434916 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0423165 |
| CALR | calreticulin | -0.0413297 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0407372 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0400306 |
| CMIP | c-Maf inducing protein | -0.0400199 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0398704 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0396578 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0396011 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0390857 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0382205 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0380847 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.038056 |
| INTS6 | integrator complex subunit 6 | -0.0376835 |
| RBM39 | RNA binding motif protein 39 | -0.0375672 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0374935 |
| RPL23 | ribosomal protein L23 | -0.0364555 |
| RRM2 | ribonucleotide reductase M2 | -0.0362708 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0355379 |
| ACTG1 | actin gamma 1 | -0.0351358 |
| ZNF638 | zinc finger protein 638 | -0.0348537 |
| PTMA | prothymosin, alpha | -0.0345248 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0338858 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0332976 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0330349 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0326263 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0325929 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0322214 |
| FUS | FUS RNA binding protein | -0.0318796 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.031847 |
| RASAL2 | RAS protein activator like 2 | -0.0318093 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0314696 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0309257 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0306334 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0305417 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0303429 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0300339 |
| MED13L | mediator complex subunit 13-like | -0.0298265 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0294945 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0294209 |
| LRRC23 | leucine rich repeat containing 23 | -0.0289445 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0289106 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0286521 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0283233 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | -0.0280319 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0275594 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0275568 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0274346 |
| ENO1 | enolase 1, (alpha) | -0.0272175 |
| DENND5A | DENN/MADD domain containing 5A | -0.0271684 |
| USP34 | ubiquitin specific peptidase 34 | -0.0266886 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0266774 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0265724 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.026537 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0265085 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0264762 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0263893 |
| CUX1 | cut-like homeobox 1 | -0.0263655 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0260939 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.025653 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.025528 |
| TPM3 | tropomyosin 3 | -0.0253229 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0252538 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0251942 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.025147 |
