| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.0492929 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.046102 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0431544 |
| VCL | vinculin | 0.0427227 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0406538 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0400202 |
| INTS6 | integrator complex subunit 6 | 0.0391258 |
| GPC6 | glypican 6 | 0.0375253 |
| NRP2 | neuropilin 2 | 0.034735 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0346429 |
| SEPTIN9 | septin 9 | 0.0344355 |
| SMAD3 | SMAD family member 3 | 0.0341586 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0339999 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0327555 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0319891 |
| KYNU | kynureninase | 0.0310343 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0299023 |
| ADM | adrenomedullin | 0.0291888 |
| EGFR | epidermal growth factor receptor | 0.0286591 |
| PALLD | palladin, cytoskeletal associated protein | 0.0273387 |
| TGFB2 | transforming growth factor, beta 2 | 0.0272838 |
| NUP98 | nucleoporin 98kDa | 0.0245058 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0243692 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0240953 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0237503 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0235934 |
| CMIP | c-Maf inducing protein | 0.023312 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0230048 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0229562 |
| TGM2 | transglutaminase 2 | 0.0224691 |
| RAD51B | RAD51 paralog B | 0.0223094 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0221544 |
| JAK1 | Janus kinase 1 | 0.0220857 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0220771 |
| MSN | moesin | 0.0217415 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0215639 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0213174 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0211539 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0211042 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0206992 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0206958 |
| PAX8 | paired box 8 | 0.0205353 |
| ITGAV | integrin, alpha V | 0.0202223 |
| MB21D2 | Mab-21 domain containing 2 | 0.0201477 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0200435 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0196042 |
| CUX1 | cut-like homeobox 1 | 0.0194514 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0194212 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0193793 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0192895 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0189943 |
| FAT1 | FAT atypical cadherin 1 | 0.0189874 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0182975 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0181688 |
| VMP1 | vacuole membrane protein 1 | 0.0179152 |
| CTBP2 | C-terminal binding protein 2 | 0.0176404 |
| PILRA | paired immunoglobin-like type 2 receptor alpha | 0.0175462 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0173989 |
| DST | dystonin | 0.0173952 |
| GOSR2 | golgi SNAP receptor complex member 2 | 0.017385 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0172399 |
| COPA | coatomer protein complex, subunit alpha | 0.0172037 |
| MKI67 | marker of proliferation Ki-67 | 0.0168757 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.01638 |
| RIC8B | RIC8 guanine nucleotide exchange factor B | 0.0163352 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0163118 |
| MYO1E | myosin IE | 0.0162961 |
| UBAP2 | ubiquitin associated protein 2 | 0.0160133 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0160079 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0159643 |
| LIMA1 | LIM domain and actin binding 1 | 0.0159085 |
| MRTFA | myocardin related transcription factor A | 0.0155554 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0154501 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.015407 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0153258 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0152857 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0151952 |
| SIK3 | SIK family kinase 3 | 0.0151914 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0149118 |
| TNS3 | tensin 3 | 0.0148315 |
| ATP13A3 | ATPase type 13A3 | 0.0147826 |
| RNF220 | ring finger protein 220 | 0.0146958 |
| USP47 | ubiquitin specific peptidase 47 | 0.0146784 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0145893 |
| BPTF | bromodomain PHD finger transcription factor | 0.0143007 |
| CPAP | centrosome assembly and centriole elongation protein | 0.0142785 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0140761 |
| CRY1 | cryptochrome circadian clock 1 | 0.0138717 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.01383 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0136806 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0135428 |
| MTAP | methylthioadenosine phosphorylase | 0.0135277 |
| GLIS3 | GLIS family zinc finger 3 | 0.0134188 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0133072 |
| SUCO | SUN domain containing ossification factor | 0.0132498 |
| VEGFA | vascular endothelial growth factor A | 0.0132417 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0131423 |
| CLIC4 | chloride intracellular channel 4 | 0.0130947 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0129372 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0129171 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.137776 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.12488 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.105457 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0907458 |
| VIM | vimentin | -0.0861956 |
| TMSB10 | thymosin beta 10 | -0.0800566 |
| ASPH | aspartate beta-hydroxylase | -0.0682234 |
| RRBP1 | ribosome binding protein 1 | -0.0675522 |
| TXNRD1 | thioredoxin reductase 1 | -0.0514203 |
| RPS4X | ribosomal protein S4, X-linked | -0.0490881 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0450195 |
| FTL | ferritin, light polypeptide | -0.0422865 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.041733 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0377712 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0373865 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0372468 |
| CANX | calnexin | -0.0372368 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0368268 |
| CALU | calumenin | -0.0368117 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0361448 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.036016 |
| RPL30 | ribosomal protein L30 | -0.0350697 |
| MAP1B | microtubule-associated protein 1B | -0.0350241 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0343929 |
| RPLP1 | ribosomal protein, large, P1 | -0.0342701 |
| ANXA2 | annexin A2 | -0.0338318 |
| LMNA | lamin A/C | -0.0336978 |
| RPS6 | ribosomal protein S6 | -0.0336896 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0331672 |
| RTN4 | reticulon 4 | -0.0327088 |
| CP | ceruloplasmin (ferroxidase) | -0.0327061 |
| GNAS | GNAS complex locus | -0.0314133 |
| HMGB1 | high mobility group box 1 | -0.03075 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0300959 |
| CBX3 | chromobox homolog 3 | -0.0299431 |
| RNF213 | ring finger protein 213 | -0.029785 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0296164 |
| TPM4 | tropomyosin 4 | -0.0292521 |
| RPL12 | ribosomal protein L12 | -0.0289346 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0289291 |
| PFN1 | profilin 1 | -0.0287617 |
| RPS19 | ribosomal protein S19 | -0.0282005 |
| RPL19 | ribosomal protein L19 | -0.0279953 |
| S100A6 | S100 calcium binding protein A6 | -0.0278742 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0276086 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0273607 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0256268 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0253924 |
| TUSC3 | tumor suppressor candidate 3 | -0.0253159 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.024821 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0245506 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0244949 |
| TKT | transketolase | -0.0243007 |
| CD44 | CD44 molecule (Indian blood group) | -0.023958 |
| RPLP0 | ribosomal protein, large, P0 | -0.0238558 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0236746 |
| RPL23 | ribosomal protein L23 | -0.0234412 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0233131 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0229028 |
| SDCBP | syndecan binding protein (syntenin) | -0.0226713 |
| B2M | beta-2-microglobulin | -0.0222047 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0215797 |
| RPL35 | ribosomal protein L35 | -0.0211753 |
| TRAM1 | translocation associated membrane protein 1 | -0.0207074 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G | -0.0206941 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0204356 |
| RIGI | RNA sensor RIG-I | -0.0203725 |
| SEPTIN7 | septin 7 | -0.0203485 |
| KLF6 | Kruppel-like factor 6 | -0.0201445 |
| RPL27A | ribosomal protein L27a | -0.0200996 |
| SRP72 | signal recognition particle 72kDa | -0.0200963 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0200501 |
| TAGLN2 | transgelin 2 | -0.0199535 |
| GDF15 | growth differentiation factor 15 | -0.019797 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0196049 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0195876 |
| HDLBP | high density lipoprotein binding protein | -0.0195667 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0195469 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0195137 |
| RPS2 | ribosomal protein S2 | -0.0195077 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.019325 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0188761 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0188008 |
| MYADM | myeloid-associated differentiation marker | -0.0184897 |
| MTDH | metadherin | -0.0184637 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0182363 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0181785 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0180363 |
| RPS5 | ribosomal protein S5 | -0.0179857 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0179755 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0179207 |
| ANXA1 | annexin A1 | -0.0178105 |
| GGNBP2 | gametogenetin binding protein 2 | -0.017718 |
| RPL36 | ribosomal protein L36 | -0.0176915 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0176531 |
| MT2A | metallothionein 2A | -0.0175127 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0174658 |
| NOP58 | NOP58 ribonucleoprotein | -0.0174422 |
| RPL7 | ribosomal protein L7 | -0.0173991 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.017368 |