| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Omeprazole (sodium)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.117104 |
| EFNA5 | ephrin-A5 | 0.0942171 |
| PDE10A | phosphodiesterase 10A | 0.0535427 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0514709 |
| VCL | vinculin | 0.0498013 |
| SMAD3 | SMAD family member 3 | 0.0434247 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0424116 |
| ACTN4 | actinin, alpha 4 | 0.0405785 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0399278 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0396398 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0394784 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0393562 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0393209 |
| EGFR | epidermal growth factor receptor | 0.0341835 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0341754 |
| ACTG1 | actin gamma 1 | 0.0331882 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0327136 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0315851 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0313373 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0311316 |
| TPM1 | tropomyosin 1 (alpha) | 0.0300264 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0299798 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0296771 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0294243 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0289428 |
| NAV2 | neuron navigator 2 | 0.0285303 |
| MYO1E | myosin IE | 0.0282539 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0278578 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0276253 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.027227 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0268083 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0265732 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0259833 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.025889 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0258422 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0256272 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0252814 |
| LAMC2 | laminin, gamma 2 | 0.0248049 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0247252 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0244064 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0242909 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0240273 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0237535 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0236487 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0232274 |
| MSI2 | musashi RNA-binding protein 2 | 0.0231469 |
| OSMR | oncostatin M receptor | 0.0229902 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0229684 |
| CMIP | c-Maf inducing protein | 0.022472 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0221352 |
| GOLGB1 | golgin B1 | 0.0216992 |
| EXOC6B | exocyst complex component 6B | 0.0216825 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0214651 |
| RIN2 | Ras and Rab interactor 2 | 0.0213376 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0212866 |
| RASA2 | RAS p21 protein activator 2 | 0.0211261 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0210728 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.020909 |
| ZNF609 | zinc finger protein 609 | 0.0207933 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0207878 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0206827 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0206078 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0203968 |
| DST | dystonin | 0.020369 |
| WDR43 | WD repeat domain 43 | 0.0198567 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0198517 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0197417 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0196854 |
| GOLGA3 | golgin A3 | 0.019665 |
| TNS1 | tensin 1 | 0.019434 |
| TNS3 | tensin 3 | 0.0194213 |
| INTS6 | integrator complex subunit 6 | 0.0192623 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0190239 |
| DENND4A | DENN/MADD domain containing 4A | 0.019011 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.018896 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0187007 |
| LOXL2 | lysyl oxidase-like 2 | 0.0186261 |
| DAPK1 | death-associated protein kinase 1 | 0.0183493 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0179582 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0179412 |
| CDK13 | cyclin-dependent kinase 13 | 0.0179358 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0178742 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0177881 |
| TCF12 | transcription factor 12 | 0.0177458 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0177235 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0177121 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0176645 |
| CUX1 | cut-like homeobox 1 | 0.0174938 |
| EHBP1 | EH domain binding protein 1 | 0.0174708 |
| SFTPA2 | surfactant protein A2 | 0.0173751 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0173524 |
| FNIP1 | folliculin interacting protein 1 | 0.0173381 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0173047 |
| FLNA | filamin A, alpha | 0.0172642 |
| PRELID2 | PRELI domain containing 2 | 0.0172418 |
| ANXA4 | annexin A4 | 0.0168268 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0167941 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.016732 |
| HMGA2 | high mobility group AT-hook 2 | 0.016372 |
| PRKCA | protein kinase C, alpha | 0.0162563 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.205527 |
| MT2A | metallothionein 2A | -0.147596 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.132918 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.125932 |
| FTL | ferritin, light polypeptide | -0.112758 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.101347 |
| MT1X | metallothionein 1X | -0.0964502 |
| RPS6 | ribosomal protein S6 | -0.0898198 |
| RPS19 | ribosomal protein S19 | -0.0849952 |
| TMSB10 | thymosin beta 10 | -0.0649774 |
| VIM | vimentin | -0.0608155 |
| PFN1 | profilin 1 | -0.0543101 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0538443 |
| RPLP1 | ribosomal protein, large, P1 | -0.050846 |
| PCBP2 | poly(rC) binding protein 2 | -0.0451497 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0437159 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.039795 |
| RPLP0 | ribosomal protein, large, P0 | -0.0368435 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0356566 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0354851 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0351234 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.034707 |
| PTMA | prothymosin, alpha | -0.034596 |
| RTN4 | reticulon 4 | -0.0340667 |
| RPL19 | ribosomal protein L19 | -0.0333002 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0331688 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0331596 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0329399 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.032867 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0323972 |
| RPL12 | ribosomal protein L12 | -0.0318063 |
| RPS5 | ribosomal protein S5 | -0.0317537 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0314321 |
| USP3 | ubiquitin specific peptidase 3 | -0.0313528 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0311115 |
| TXNRD1 | thioredoxin reductase 1 | -0.03097 |
| UBC | ubiquitin C | -0.0305876 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0297964 |
| RPS16 | ribosomal protein S16 | -0.0297211 |
| S100A6 | S100 calcium binding protein A6 | -0.0293566 |
| NDRG1 | N-myc downstream regulated 1 | -0.0289656 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0286539 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0286426 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0285808 |
| LDHA | lactate dehydrogenase A | -0.0284359 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0274196 |
| HMGA1 | high mobility group AT-hook 1 | -0.0272211 |
| RPL18 | ribosomal protein L18 | -0.0271506 |
| RPS8 | ribosomal protein S8 | -0.0265265 |
| RPL23 | ribosomal protein L23 | -0.0265066 |
| RPS23 | ribosomal protein S23 | -0.0261924 |
| TKT | transketolase | -0.0260587 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0259354 |
| MYADM | myeloid-associated differentiation marker | -0.0248851 |
| TPI1 | triosephosphate isomerase 1 | -0.0246743 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0243519 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0243068 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0240319 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0235982 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0235492 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0234712 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0233344 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0231579 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0227701 |
| FOSL1 | FOS-like antigen 1 | -0.0225743 |
| RPS13 | ribosomal protein S13 | -0.0223531 |
| PKM | pyruvate kinase, muscle | -0.0219901 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0218048 |
| PERP | PERP, TP53 apoptosis effector | -0.0217732 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0211577 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0210218 |
| EREG | epiregulin | -0.0209575 |
| CCNL1 | cyclin L1 | -0.0206662 |
| S100A10 | S100 calcium binding protein A10 | -0.0205064 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0197426 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0195834 |
| WDR45B | WD repeat domain 45B | -0.0194152 |
| RPL32 | ribosomal protein L32 | -0.0193412 |
| RACK1 | receptor for activated C kinase 1 | -0.0190698 |
| RPS14 | ribosomal protein S14 | -0.0190252 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0189384 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.018937 |
| CENPF | centromere protein F, 350/400kDa | -0.0186673 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0185192 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0182501 |
| ENO1 | enolase 1, (alpha) | -0.0182096 |
| AXL | AXL receptor tyrosine kinase | -0.0181556 |
| RNF24 | ring finger protein 24 | -0.0179604 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0178618 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0177091 |
| RPL9 | ribosomal protein L9 | -0.0175393 |
| CDCA2 | cell division cycle associated 2 | -0.0173264 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0173259 |
| RPS11 | ribosomal protein S11 | -0.0169418 |
| RPS27L | ribosomal protein S27-like | -0.0167553 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0165589 |
| TUBA1B | tubulin, alpha 1b | -0.0163612 |
| CA12 | carbonic anhydrase XII | -0.0162987 |
| RPS12 | ribosomal protein S12 | -0.0162276 |
| ADM | adrenomedullin | -0.0162147 |
