| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.356247 |
| PEG10 | paternally expressed 10 | 0.111315 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.102734 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0942644 |
| CALR | calreticulin | 0.0651938 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0595508 |
| ZNF292 | zinc finger protein 292 | 0.0543827 |
| VCL | vinculin | 0.051846 |
| RNF145 | ring finger protein 145 | 0.0503242 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0495047 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0459183 |
| ITGAV | integrin, alpha V | 0.045204 |
| MEOX2 | mesenchyme homeobox 2 | 0.0447319 |
| SFTPA2 | surfactant protein A2 | 0.0441482 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0440341 |
| ANKRD17 | ankyrin repeat domain 17 | 0.043841 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0423057 |
| MKI67 | marker of proliferation Ki-67 | 0.0418713 |
| ENAH | enabled homolog (Drosophila) | 0.0417899 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0413387 |
| RPS2 | ribosomal protein S2 | 0.0410809 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.040594 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0404819 |
| MATR3 | matrin 3 | 0.0404164 |
| ENO1 | enolase 1, (alpha) | 0.0400295 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0398041 |
| PCM1 | pericentriolar material 1 | 0.0377601 |
| GOLGA4 | golgin A4 | 0.0369565 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0349025 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0344104 |
| SNX3 | sorting nexin 3 | 0.0338444 |
| RPL3 | ribosomal protein L3 | 0.0333685 |
| RBM39 | RNA binding motif protein 39 | 0.0328224 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0327837 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.0324078 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0320817 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0318606 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0312592 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0310929 |
| OGA | O-GlcNAcase | 0.0310732 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0309348 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0307922 |
| TMSB4X | thymosin beta 4, X-linked | 0.0307918 |
| SEPTIN11 | septin 11 | 0.0307598 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0303747 |
| SET | SET nuclear proto-oncogene | 0.0302805 |
| GMPS | guanine monphosphate synthase | 0.030195 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.029208 |
| MED13L | mediator complex subunit 13-like | 0.0290985 |
| UTRN | utrophin | 0.0290325 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0287188 |
| RSBN1L | round spermatid basic protein 1-like | 0.028712 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0284219 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0279737 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0279153 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0278991 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0277031 |
| CENPF | centromere protein F, 350/400kDa | 0.0276366 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0274743 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0274659 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0270203 |
| KLHDC10 | kelch domain containing 10 | 0.0268842 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0267952 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0267814 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0267642 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0267137 |
| TXNRD1 | thioredoxin reductase 1 | 0.0265683 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0264497 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0261384 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0260172 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0258568 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.0258388 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0255555 |
| YBX1 | Y box binding protein 1 | 0.0254008 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0250961 |
| B2M | beta-2-microglobulin | 0.0250106 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0248577 |
| BUB3 | BUB3 mitotic checkpoint protein | 0.0248233 |
| TNPO1 | transportin 1 | 0.0247924 |
| SETD2 | SET domain containing 2 | 0.0246672 |
| GTF2I | general transcription factor IIi | 0.0246369 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0245981 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0245643 |
| SGCE | sarcoglycan, epsilon | 0.0245599 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0244273 |
| CEP350 | centrosomal protein 350kDa | 0.0242077 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0241228 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.024096 |
| TPK1 | thiamin pyrophosphokinase 1 | 0.0236607 |
| PAPOLA | poly(A) polymerase alpha | 0.0235964 |
| PTMA | prothymosin, alpha | 0.0235388 |
| SEPTIN2 | septin 2 | 0.0235188 |
| TLK1 | tousled-like kinase 1 | 0.0234167 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0234086 |
| R3HDM1 | R3H domain containing 1 | 0.023299 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0230117 |
| SON | SON DNA binding protein | 0.0229851 |
| BOC | BOC cell adhesion associated, oncogene regulated | 0.0229109 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0227479 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0226852 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.126746 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.119778 |
| CADM2 | cell adhesion molecule 2 | -0.101894 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0731646 |
| HMGA2 | high mobility group AT-hook 2 | -0.0704342 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0685112 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0570821 |
| MYOF | myoferlin | -0.0510261 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0490713 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0486184 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0476411 |
| RPS24 | ribosomal protein S24 | -0.041811 |
| EXOC4 | exocyst complex component 4 | -0.0415991 |
| CTBP2 | C-terminal binding protein 2 | -0.040389 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0396341 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0395854 |
| IER3 | immediate early response 3 | -0.0380912 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0370418 |
| DENND5A | DENN/MADD domain containing 5A | -0.035882 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0357693 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0348077 |
| DMXL1 | Dmx-like 1 | -0.034564 |
| RPL28 | ribosomal protein L28 | -0.0341066 |
| ANO6 | anoctamin 6 | -0.0339926 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0334182 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0333251 |
| MEIS2 | Meis homeobox 2 | -0.0332172 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0324941 |
| FBXO11 | F-box protein 11 | -0.0302898 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.030063 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0296745 |
| NBEA | neurobeachin | -0.0295582 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0293925 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0290099 |
| GPC6 | glypican 6 | -0.0284168 |
| VIM | vimentin | -0.0278525 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0277888 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0275801 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0271559 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0268658 |
| SMYD3 | SET and MYND domain containing 3 | -0.026044 |
| DENND1A | DENN/MADD domain containing 1A | -0.0259943 |
| INTS6 | integrator complex subunit 6 | -0.0256754 |
| TMSB10 | thymosin beta 10 | -0.0255136 |
| RPLP1 | ribosomal protein, large, P1 | -0.025432 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0252117 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0251236 |
| TRIM9 | tripartite motif containing 9 | -0.0241051 |
| FLNB | filamin B, beta | -0.0240517 |
| RSU1 | Ras suppressor protein 1 | -0.0238433 |
| HBP1 | HMG-box transcription factor 1 | -0.0237314 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0235714 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0231883 |
| DIAPH2 | diaphanous-related formin 2 | -0.0231645 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0231081 |
| FRMD6 | FERM domain containing 6 | -0.0228215 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0227973 |
| JAM3 | junctional adhesion molecule 3 | -0.0226903 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0225582 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0223065 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.0220831 |
| ANK2 | ankyrin 2, neuronal | -0.0219465 |
| RPLP2 | ribosomal protein, large, P2 | -0.0217467 |
| CMIP | c-Maf inducing protein | -0.0217238 |
| PARD3 | par-3 family cell polarity regulator | -0.0215595 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0214596 |
| PRKCE | protein kinase C, epsilon | -0.021164 |
| RAI1 | retinoic acid induced 1 | -0.020952 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0209135 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0208514 |
| EVL | Enah/Vasp-like | -0.0206916 |
| DENND5B | DENN/MADD domain containing 5B | -0.0205258 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0204979 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0204553 |
| ATXN2 | ataxin 2 | -0.0203887 |
| JMJD1C | jumonji domain containing 1C | -0.0203416 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0200628 |
| RPL35A | ribosomal protein L35a | -0.0200616 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | -0.0199221 |
| ZFHX3 | zinc finger homeobox 3 | -0.0199052 |
| NHSL1 | NHS-like 1 | -0.0198262 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0194607 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.019457 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0192768 |
| LRRC23 | leucine rich repeat containing 23 | -0.0192584 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0190169 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0189751 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0189286 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0188648 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0187643 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0186856 |
| MSI2 | musashi RNA-binding protein 2 | -0.0186734 |
| FBXO33 | F-box protein 33 | -0.0185084 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0183755 |
| AOPEP | aminopeptidase O (putative) | -0.0182471 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0181793 |
| PBRM1 | polybromo 1 | -0.0181569 |
| HMGB1 | high mobility group box 1 | -0.0180741 |
| AHI1 | Abelson helper integration site 1 | -0.0180497 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0179605 |