| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.24306 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.112037 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0816909 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0717477 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0668418 |
| SLMAP | sarcolemma associated protein | 0.0639054 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0577372 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.0531458 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0452761 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0420265 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0401924 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0380008 |
| PGK1 | phosphoglycerate kinase 1 | 0.0373619 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0363172 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.036065 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0349769 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0348021 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 0.0342139 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0339965 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0331963 |
| POTEF | POTE ankyrin domain family, member F | 0.0327769 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.032362 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0321832 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0309965 |
| MXD1 | MAX dimerization protein 1 | 0.0305886 |
| NUP58 | nucleoporin 58 | 0.0301524 |
| TMEM41B | transmembrane protein 41B | 0.029302 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0287262 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0285855 |
| CORO1C | coronin, actin binding protein, 1C | 0.0278567 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0277798 |
| ZNF292 | zinc finger protein 292 | 0.0265649 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0263056 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0259674 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0254516 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0254331 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0252059 |
| MYO6 | myosin VI | 0.0247134 |
| RCOR1 | REST corepressor 1 | 0.0247026 |
| ATP13A3 | ATPase type 13A3 | 0.0246233 |
| FAM107B | family with sequence similarity 107, member B | 0.0245913 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0245375 |
| NEK7 | NIMA-related kinase 7 | 0.0241265 |
| SNX9 | sorting nexin 9 | 0.0240769 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.0239887 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0238784 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0231192 |
| NCKAP1 | NCK-associated protein 1 | 0.0230383 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0229314 |
| MUC17 | mucin 17, cell surface associated | 0.0225429 |
| SLK | STE20-like kinase | 0.0223142 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0223109 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0219583 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0216318 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0215718 |
| TPM3 | tropomyosin 3 | 0.0215456 |
| UPP1 | uridine phosphorylase 1 | 0.0211773 |
| FOSL1 | FOS-like antigen 1 | 0.0208706 |
| GDA | guanine deaminase | 0.0205437 |
| HPCAL1 | hippocalcin-like 1 | 0.0204847 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0203134 |
| MCU | mitochondrial calcium uniporter | 0.0202348 |
| TMF1 | TATA element modulatory factor 1 | 0.0199161 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0197167 |
| USP3 | ubiquitin specific peptidase 3 | 0.019339 |
| CD164 | CD164 molecule, sialomucin | 0.0190721 |
| FA2H | fatty acid 2-hydroxylase | 0.0188788 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0187969 |
| RNF145 | ring finger protein 145 | 0.018695 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0186675 |
| LMO7 | LIM domain 7 | 0.0186334 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0186071 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0185906 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0184371 |
| CCNL1 | cyclin L1 | 0.0183421 |
| UBAP1 | ubiquitin associated protein 1 | 0.018092 |
| THOC2 | THO complex 2 | 0.0179854 |
| C1ORF52 | chromosome 1 open reading frame 52 | 0.0176694 |
| MATR3 | matrin 3 | 0.0176204 |
| TJP2 | tight junction protein 2 | 0.0175644 |
| CLINT1 | clathrin interactor 1 | 0.0175163 |
| RHOF | ras homolog family member F (in filopodia) | 0.0171531 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0169551 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0168818 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0167956 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.016749 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.016636 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0165662 |
| PROSER2 | proline and serine rich 2 | 0.0165156 |
| SULF2 | sulfatase 2 | 0.0163814 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0163757 |
| CDC42SE2 | CDC42 small effector 2 | 0.0160356 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0159831 |
| OPTN | optineurin | 0.0159722 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0159565 |
| ABI1 | abl-interactor 1 | 0.0158279 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0155152 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0154844 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0154162 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0153587 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.167069 |
| TMSB10 | thymosin beta 10 | -0.160064 |
| EFNA5 | ephrin-A5 | -0.132103 |
| LAMB3 | laminin, beta 3 | -0.118987 |
| EGFR | epidermal growth factor receptor | -0.114684 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.104216 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.102379 |
| NDRG1 | N-myc downstream regulated 1 | -0.0960315 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0931757 |
| ASPH | aspartate beta-hydroxylase | -0.0877616 |
| ANXA2 | annexin A2 | -0.0873737 |
| AHNAK | AHNAK nucleoprotein | -0.0786167 |
| HMGA2 | high mobility group AT-hook 2 | -0.0714691 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0685923 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0679233 |
| S100A10 | S100 calcium binding protein A10 | -0.0675838 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0674538 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0664466 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0645861 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0624172 |
| NPSR1 | neuropeptide S receptor 1 | -0.0608295 |
| VIM | vimentin | -0.0601285 |
| INTS6 | integrator complex subunit 6 | -0.0589031 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.05818 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0579261 |
| LAMA4 | laminin, alpha 4 | -0.056307 |
| DIAPH2 | diaphanous-related formin 2 | -0.055197 |
| FLNB | filamin B, beta | -0.0546419 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0543029 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0542612 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0537632 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0512432 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0508018 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.050671 |
| SP100 | SP100 nuclear antigen | -0.0504629 |
| HDAC9 | histone deacetylase 9 | -0.0488668 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0481386 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0474431 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0462289 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.04555 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0444754 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0442305 |
| RPLP1 | ribosomal protein, large, P1 | -0.0435447 |
| PMM2 | phosphomannomutase 2 | -0.0427933 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0426671 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0424368 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.042427 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0417509 |
| NABP1 | nucleic acid binding protein 1 | -0.0412283 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0401779 |
| SMAD3 | SMAD family member 3 | -0.0399531 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0391453 |
| RASAL2 | RAS protein activator like 2 | -0.0388749 |
| LAMC2 | laminin, gamma 2 | -0.0386949 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0384057 |
| EHBP1 | EH domain binding protein 1 | -0.0382668 |
| HDLBP | high density lipoprotein binding protein | -0.0372206 |
| SDC4 | syndecan 4 | -0.0367292 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0364569 |
| PRELID2 | PRELI domain containing 2 | -0.036187 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0360286 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0359681 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0357338 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0356486 |
| ACTN4 | actinin, alpha 4 | -0.0353854 |
| RNF213 | ring finger protein 213 | -0.035276 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0352375 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0351233 |
| RIGI | RNA sensor RIG-I | -0.034706 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0340915 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0339702 |
| MYOF | myoferlin | -0.0339416 |
| PLEC | plectin | -0.033536 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0334668 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0334172 |
| MCL1 | myeloid cell leukemia 1 | -0.0328992 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0327172 |
| RPL23 | ribosomal protein L23 | -0.032686 |
| FBXO11 | F-box protein 11 | -0.0325401 |
| MYO1E | myosin IE | -0.0323695 |
| TGM2 | transglutaminase 2 | -0.0321758 |
| CDK13 | cyclin-dependent kinase 13 | -0.0320313 |
| FUS | FUS RNA binding protein | -0.0320033 |
| RPS6 | ribosomal protein S6 | -0.0314627 |
| RRBP1 | ribosome binding protein 1 | -0.0314279 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0311651 |
| RAD51B | RAD51 paralog B | -0.0310389 |
| ENO1 | enolase 1, (alpha) | -0.0309906 |
| EXOC4 | exocyst complex component 4 | -0.0308809 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0305813 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0303865 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0301411 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0299886 |
| SEM1 | SEM1 26S proteasome subunit | -0.0298166 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0293988 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0293242 |
| GOLGB1 | golgin B1 | -0.0292954 |
| MT2A | metallothionein 2A | -0.0290861 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0287812 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0286617 |
