| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.118491 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0729614 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0652831 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.060638 |
| VMP1 | vacuole membrane protein 1 | 0.0600534 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0536298 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.047303 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.04705 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0418945 |
| OSMR | oncostatin M receptor | 0.0410703 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0396175 |
| TMEM165 | transmembrane protein 165 | 0.0369322 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.036563 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0356759 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0354819 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0352373 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0332519 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0331114 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0329161 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0306825 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0301436 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0283978 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0281133 |
| DOCK5 | dedicator of cytokinesis 5 | 0.027601 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.0269861 |
| TMEM45B | transmembrane protein 45B | 0.0269672 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0264662 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0264225 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.0261085 |
| EZR | ezrin | 0.0257133 |
| LDLR | low density lipoprotein receptor | 0.0244948 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0241465 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0239977 |
| USP53 | ubiquitin specific peptidase 53 | 0.0237935 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.0237792 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | 0.0233199 |
| NTN4 | netrin 4 | 0.0232877 |
| KAZN | kazrin, periplakin interacting protein | 0.0227709 |
| KIAA1217 | KIAA1217 | 0.0226657 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0225488 |
| CFB | complement factor B | 0.0221738 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0219551 |
| INSIG1 | insulin induced gene 1 | 0.0217804 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0215406 |
| ABHD17C | abhydrolase domain containing 17C | 0.0215152 |
| FADS2 | fatty acid desaturase 2 | 0.0213256 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0211289 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0210444 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0206375 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0205928 |
| CCNL1 | cyclin L1 | 0.0205564 |
| KLF6 | Kruppel-like factor 6 | 0.0202912 |
| TP53INP2 | tumor protein p53 inducible nuclear protein 2 | 0.0201045 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | 0.0197827 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.019619 |
| DUSP16 | dual specificity phosphatase 16 | 0.0195476 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0192519 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0191544 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.0186999 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0177836 |
| TC2N | tandem C2 domains, nuclear | 0.0177228 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0176582 |
| VEGFA | vascular endothelial growth factor A | 0.0176022 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0176021 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0175977 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0175678 |
| RESF1 | retroelement silencing factor 1 | 0.0175185 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0174661 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0169018 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0168309 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.0167761 |
| AHR | aryl hydrocarbon receptor | 0.016757 |
| RAB22A | RAB22A, member RAS oncogene family | 0.016367 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0163542 |
| S100A9 | S100 calcium binding protein A9 | 0.0162828 |
| PGK1 | phosphoglycerate kinase 1 | 0.0161275 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0161042 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.015882 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0158647 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0158025 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.0157981 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.0156191 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0155223 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0154449 |
| DSG2 | desmoglein 2 | 0.0152317 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0151216 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0151094 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0149809 |
| CD9 | CD9 molecule | 0.0149788 |
| PLK2 | polo-like kinase 2 | 0.0149514 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0149473 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0149197 |
| SERINC3 | serine incorporator 3 | 0.0149179 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0148322 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0147689 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0146955 |
| DUSP4 | dual specificity phosphatase 4 | 0.0145645 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0144735 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0144355 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.014415 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.243355 |
| RPL19 | ribosomal protein L19 | -0.211103 |
| INTS6 | integrator complex subunit 6 | -0.0805537 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0665896 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.066272 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.063245 |
| CEP250 | centrosomal protein 250kDa | -0.0626257 |
| CDK12 | cyclin-dependent kinase 12 | -0.0572395 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.052447 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0519302 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0497792 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0490792 |
| RPL37A | ribosomal protein L37a | -0.0472834 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0460548 |
| ACTG1 | actin gamma 1 | -0.0448838 |
| SP100 | SP100 nuclear antigen | -0.0420799 |
| DTNA | dystrobrevin, alpha | -0.0410484 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0410029 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0405162 |
| RPL35A | ribosomal protein L35a | -0.0405092 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0399277 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0384232 |
| DENND1A | DENN/MADD domain containing 1A | -0.0384031 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0376443 |
| STXBP4 | syntaxin binding protein 4 | -0.0361074 |
| PLSCR2 | phospholipid scramblase 2 | -0.0345951 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0345776 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0344394 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0342304 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0340592 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0338529 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0336754 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | -0.0327651 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0323081 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0322408 |
| EFNA5 | ephrin-A5 | -0.031712 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0317078 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0313893 |
| VCP | valosin containing protein | -0.0303908 |
| RAD51B | RAD51 paralog B | -0.0297706 |
| RPS3 | ribosomal protein S3 | -0.0292733 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.02898 |
| CDK13 | cyclin-dependent kinase 13 | -0.0288791 |
| EXOC4 | exocyst complex component 4 | -0.0281912 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0281365 |
| RTN3 | reticulon 3 | -0.0280667 |
| PTK2 | protein tyrosine kinase 2 | -0.0278815 |
| CANX | calnexin | -0.0278665 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0278587 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0276936 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0273252 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | -0.0271956 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0271056 |
| ZNF207 | zinc finger protein 207 | -0.0269022 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0261171 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0261074 |
| UBAP2 | ubiquitin associated protein 2 | -0.0259432 |
| KRT86 | keratin 86, type II | -0.0255485 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0251754 |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit | -0.0249997 |
| MCL1 | myeloid cell leukemia 1 | -0.0249413 |
| RPL31 | ribosomal protein L31 | -0.0248208 |
| NDRG1 | N-myc downstream regulated 1 | -0.0246762 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0245558 |
| AEBP2 | AE binding protein 2 | -0.024442 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0240757 |
| MMP24OS | MMP24 opposite strand | -0.0240516 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0236819 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0234517 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.02334 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0232779 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.023209 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0232068 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.023096 |
| MSI2 | musashi RNA-binding protein 2 | -0.0230871 |
| PARD3 | par-3 family cell polarity regulator | -0.0228064 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.0226627 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0225289 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0225043 |
| ENO1 | enolase 1, (alpha) | -0.0222791 |
| RCOR1 | REST corepressor 1 | -0.0222761 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0221485 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0221408 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0221121 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0219731 |
| RPL27A | ribosomal protein L27a | -0.0219536 |
| MED13 | mediator complex subunit 13 | -0.0218986 |
| PRKCA | protein kinase C, alpha | -0.0218457 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0217863 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.021677 |
| RPS6 | ribosomal protein S6 | -0.0215302 |
| ANKRD12 | ankyrin repeat domain 12 | -0.021367 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0213237 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0212259 |
| SBF2 | SET binding factor 2 | -0.021183 |
| NABP1 | nucleic acid binding protein 1 | -0.0210084 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0210068 |
| RPS8 | ribosomal protein S8 | -0.0208133 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0207602 |
| RPL37 | ribosomal protein L37 | -0.0205622 |
