| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Omeprazole (sodium)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NPAS3 | neuronal PAS domain protein 3 | 0.18541 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.141348 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.109206 |
| NEBL | nebulette | 0.0900532 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0824948 |
| RAD51B | RAD51 paralog B | 0.0666576 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0656447 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0622927 |
| EFNA5 | ephrin-A5 | 0.0529552 |
| SHROOM3 | shroom family member 3 | 0.0511164 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0445049 |
| RPL11 | ribosomal protein L11 | 0.0439655 |
| PGK1 | phosphoglycerate kinase 1 | 0.0431663 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0426493 |
| FMNL2 | formin-like 2 | 0.0412468 |
| TOX | thymocyte selection-associated high mobility group box | 0.0388175 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0380532 |
| TENM3 | teneurin transmembrane protein 3 | 0.0361404 |
| ENO1 | enolase 1, (alpha) | 0.0352724 |
| LDHA | lactate dehydrogenase A | 0.0350354 |
| FAT1 | FAT atypical cadherin 1 | 0.0349077 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.032764 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0319536 |
| HMGA1 | high mobility group AT-hook 1 | 0.0316821 |
| SET | SET nuclear proto-oncogene | 0.0315569 |
| WLS | wntless Wnt ligand secretion mediator | 0.0312575 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0311007 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0309194 |
| ZNF292 | zinc finger protein 292 | 0.0288034 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0287394 |
| PNN | pinin, desmosome associated protein | 0.0287249 |
| HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | 0.0281512 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0281333 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0281014 |
| RPS11 | ribosomal protein S11 | 0.0280663 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0277229 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0276049 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0270542 |
| RBM25 | RNA binding motif protein 25 | 0.0267844 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0264662 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0262486 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0258992 |
| SMYD3 | SET and MYND domain containing 3 | 0.0258954 |
| PEG10 | paternally expressed 10 | 0.0254216 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.0250463 |
| MKI67 | marker of proliferation Ki-67 | 0.0249972 |
| PTK2 | protein tyrosine kinase 2 | 0.0248787 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0245556 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0242934 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0242851 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0239369 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0231273 |
| RPL18 | ribosomal protein L18 | 0.0223634 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0223361 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0222612 |
| SHPRH | SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase | 0.0217678 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0217023 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0214875 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0211639 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.021031 |
| DOCK1 | dedicator of cytokinesis 1 | 0.020894 |
| RPL3 | ribosomal protein L3 | 0.0208293 |
| PAPOLA | poly(A) polymerase alpha | 0.0207619 |
| HDAC2 | histone deacetylase 2 | 0.0205817 |
| LMNB1 | lamin B1 | 0.0205612 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0205135 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0204166 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0201553 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0201512 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.020127 |
| VMP1 | vacuole membrane protein 1 | 0.0200176 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.01998 |
| VEGFC | vascular endothelial growth factor C | 0.0198988 |
| CHRM3 | cholinergic receptor, muscarinic 3 | 0.0198814 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0197941 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.019463 |
| COX5A | cytochrome c oxidase subunit Va | 0.0194566 |
| ZNF608 | zinc finger protein 608 | 0.0194408 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0194284 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0194257 |
| RFX7 | regulatory factor X, 7 | 0.0192681 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.019254 |
| TOB2 | transducer of ERBB2, 2 | 0.0190587 |
| TMEM14B | transmembrane protein 14B | 0.0190206 |
| SRP9 | signal recognition particle 9kDa | 0.0189551 |
| RNF220 | ring finger protein 220 | 0.0188593 |
| PCDH9 | protocadherin 9 | 0.0187687 |
| ZNF721 | zinc finger protein 721 | 0.0187004 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0186627 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0186552 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | 0.018472 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0184666 |
| GTPBP4 | GTP binding protein 4 | 0.0184181 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.0183778 |
| ADAR | adenosine deaminase, RNA-specific | 0.0183429 |
| TNPO3 | transportin 3 | 0.0182241 |
| NEO1 | neogenin 1 | 0.0181082 |
| DEK | DEK proto-oncogene | 0.0180753 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0180158 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0179682 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.100599 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0815338 |
| CADM2 | cell adhesion molecule 2 | -0.0606968 |
| JMJD1C | jumonji domain containing 1C | -0.058922 |
| RIGI | RNA sensor RIG-I | -0.0524107 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0470629 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0444631 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0419037 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0418836 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0416063 |
| HOMER1 | homer scaffolding protein 1 | -0.0409579 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0403906 |
| GNAS | GNAS complex locus | -0.0387426 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0385466 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0382164 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0374306 |
| SYAP1 | synapse associated protein 1 | -0.0373384 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.037304 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0369128 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0361742 |
| NFIB | nuclear factor I/B | -0.0356724 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0356668 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0354213 |
| FN1 | fibronectin 1 | -0.0346841 |
| ATP11A | ATPase, class VI, type 11A | -0.0346103 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0345346 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0334672 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0334193 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0329714 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.032701 |
| VWA8 | von Willebrand factor A domain containing 8 | -0.0323655 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0322507 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0321972 |
| EXOC6B | exocyst complex component 6B | -0.0317565 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0315981 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.031326 |
| FBXO11 | F-box protein 11 | -0.0311465 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0309063 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0306566 |
| MED13 | mediator complex subunit 13 | -0.0301161 |
| COL5A2 | collagen, type V, alpha 2 | -0.0300613 |
| NBEAL1 | neurobeachin-like 1 | -0.0298722 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0290792 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.029056 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.028868 |
| RBM39 | RNA binding motif protein 39 | -0.0287919 |
| PMP22 | peripheral myelin protein 22 | -0.0287248 |
| OLA1 | Obg-like ATPase 1 | -0.0285487 |
| FOSL2 | FOS-like antigen 2 | -0.0281582 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0281404 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0279671 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0279215 |
| PCNX4 | pecanex 4 | -0.0279024 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0276213 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.027458 |
| AHI1 | Abelson helper integration site 1 | -0.0270481 |
| USP34 | ubiquitin specific peptidase 34 | -0.026808 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0261627 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.025632 |
| OGA | O-GlcNAcase | -0.0255017 |
| YBX1 | Y box binding protein 1 | -0.0254221 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0254077 |
| NDRG1 | N-myc downstream regulated 1 | -0.0241316 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0240887 |
| TTC19 | tetratricopeptide repeat domain 19 | -0.0240564 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0240116 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0239671 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0238375 |
| SON | SON DNA binding protein | -0.0236569 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0235265 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0235092 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.023505 |
| RTN4 | reticulon 4 | -0.0234941 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.023351 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0230506 |
| ZNF10 | zinc finger protein 10 | -0.022891 |
| KDM6B | lysine (K)-specific demethylase 6B | -0.0227619 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.0226024 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0225439 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0223293 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0221645 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0221394 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0220996 |
| RPS20 | ribosomal protein S20 | -0.022009 |
| HMGB1 | high mobility group box 1 | -0.02193 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0217217 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0214491 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0213563 |
| RASAL2 | RAS protein activator like 2 | -0.0212798 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0212248 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0210728 |
| RPS24 | ribosomal protein S24 | -0.0210094 |
| FAM13A | family with sequence similarity 13, member A | -0.0208468 |
| TPD52 | tumor protein D52 | -0.0208069 |
| RHEB | Ras homolog enriched in brain | -0.0207794 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0207776 |
| RASA2 | RAS p21 protein activator 2 | -0.0205967 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0205949 |
| MORF4L2 | mortality factor 4 like 2 | -0.020386 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0203557 |
