| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.054641 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0440138 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.040118 |
| NDRG1 | N-myc downstream regulated 1 | 0.0361554 |
| MEF2A | myocyte enhancer factor 2A | 0.0335573 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0313686 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0313511 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0308842 |
| SPAG9 | sperm associated antigen 9 | 0.0303642 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0302639 |
| FAM13A | family with sequence similarity 13, member A | 0.0276235 |
| LAMA4 | laminin, alpha 4 | 0.0247009 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0244216 |
| RAB8B | RAB8B, member RAS oncogene family | 0.023841 |
| RTN4 | reticulon 4 | 0.0230138 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0205389 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0204712 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0204137 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0197446 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0192259 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0186661 |
| PGK1 | phosphoglycerate kinase 1 | 0.0183641 |
| PDZD8 | PDZ domain containing 8 | 0.0182937 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0181035 |
| POTEF | POTE ankyrin domain family, member F | 0.0180726 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0172803 |
| FNBP1L | formin binding protein 1-like | 0.0172677 |
| LAMC2 | laminin, gamma 2 | 0.0170901 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0164797 |
| EZR | ezrin | 0.0156624 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0155573 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.014425 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0143827 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0142371 |
| INSIG2 | insulin induced gene 2 | 0.0141834 |
| ABI1 | abl-interactor 1 | 0.0140778 |
| FLNB | filamin B, beta | 0.0140701 |
| RNF149 | ring finger protein 149 | 0.0139068 |
| SNX9 | sorting nexin 9 | 0.0138626 |
| CCNL1 | cyclin L1 | 0.0138254 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0137861 |
| TFG | TRK-fused gene | 0.0136734 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0135092 |
| HPCAL1 | hippocalcin-like 1 | 0.0134962 |
| AREG | amphiregulin | 0.0134174 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0134073 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.01328 |
| CDCP1 | CUB domain containing protein 1 | 0.0128835 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0128827 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0125147 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0123972 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0123811 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0120283 |
| ASPH | aspartate beta-hydroxylase | 0.0120226 |
| FOSL1 | FOS-like antigen 1 | 0.0119516 |
| HELZ | helicase with zinc finger | 0.0119495 |
| PEG10 | paternally expressed 10 | 0.0118805 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0114183 |
| YTHDC1 | YTH domain containing 1 | 0.0113006 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.011282 |
| CLDN4 | claudin 4 | 0.011224 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0112004 |
| ANO6 | anoctamin 6 | 0.0110457 |
| OPTN | optineurin | 0.0109938 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0109672 |
| OGA | O-GlcNAcase | 0.0108281 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0107759 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0107679 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0107425 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | 0.0105593 |
| CDK17 | cyclin-dependent kinase 17 | 0.0103286 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.010307 |
| NUP58 | nucleoporin 58 | 0.0103032 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.010216 |
| INSIG1 | insulin induced gene 1 | 0.0100957 |
| AFDN | afadin, adherens junction formation factor | 0.0100254 |
| TOP1 | topoisomerase (DNA) I | 0.0100001 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.00999697 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.00993453 |
| SLTM | SAFB-like, transcription modulator | 0.00979392 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.00967038 |
| IRF6 | interferon regulatory factor 6 | 0.00965207 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.00955404 |
| CD2AP | CD2-associated protein | 0.00951277 |
| HDAC3 | histone deacetylase 3 | 0.00947235 |
| MATR3 | matrin 3 | 0.00941688 |
| PLAU | plasminogen activator, urokinase | 0.00935208 |
| USP3 | ubiquitin specific peptidase 3 | 0.00934777 |
| RASA2 | RAS p21 protein activator 2 | 0.00930429 |
| RAB6A | RAB6A, member RAS oncogene family | 0.009288 |
| WAC | WW domain containing adaptor with coiled-coil | 0.00925574 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00922144 |
| MAP1B | microtubule-associated protein 1B | 0.00912393 |
| SLK | STE20-like kinase | 0.00902984 |
| FAM117B | family with sequence similarity 117, member B | 0.00881871 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0087693 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.00871235 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00867309 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.00864826 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.00863037 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CP | ceruloplasmin (ferroxidase) | -0.0784309 |
| TMSB10 | thymosin beta 10 | -0.0779804 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0695542 |
| MMP7 | matrix metallopeptidase 7 | -0.0670003 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0658732 |
| HLA-B | major histocompatibility complex, class I, B | -0.059478 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0572727 |
| PTMA | prothymosin, alpha | -0.0563177 |
| B2M | beta-2-microglobulin | -0.0500191 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0486796 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0444877 |
| RPL23 | ribosomal protein L23 | -0.0428854 |
| MT2A | metallothionein 2A | -0.0415301 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0404749 |
| LAMB3 | laminin, beta 3 | -0.0399149 |
| EFNA5 | ephrin-A5 | -0.0392611 |
| S100A6 | S100 calcium binding protein A6 | -0.038902 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0382554 |
| RPLP1 | ribosomal protein, large, P1 | -0.0376566 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.036188 |
| RPL19 | ribosomal protein L19 | -0.0345208 |
| RPS8 | ribosomal protein S8 | -0.0342366 |
| SP100 | SP100 nuclear antigen | -0.0335472 |
| HLA-A | major histocompatibility complex, class I, A | -0.0325193 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0321901 |
| VIM | vimentin | -0.0317061 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0314281 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0314139 |
| RNF213 | ring finger protein 213 | -0.0310567 |
| NRG3 | neuregulin 3 | -0.0310553 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0304811 |
| MX1 | MX dynamin-like GTPase 1 | -0.0299607 |
| ENO1 | enolase 1, (alpha) | -0.029939 |
| APOL1 | apolipoprotein L, 1 | -0.0299387 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0289109 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0287147 |
| RPL35A | ribosomal protein L35a | -0.0286796 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0286513 |
| HLA-E | major histocompatibility complex, class I, E | -0.0283605 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0283224 |
| NABP1 | nucleic acid binding protein 1 | -0.0281505 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0273535 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0267194 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0267075 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.026673 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0262122 |
| RPS6 | ribosomal protein S6 | -0.0255926 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.02545 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0249922 |
| RPS24 | ribosomal protein S24 | -0.0248036 |
| FTL | ferritin, light polypeptide | -0.0242869 |
| RPL37A | ribosomal protein L37a | -0.0241602 |
| LCN2 | lipocalin 2 | -0.0238948 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.023338 |
| RPL11 | ribosomal protein L11 | -0.0231514 |
| MX2 | MX dynamin-like GTPase 2 | -0.0228986 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0228729 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0224032 |
| PKM | pyruvate kinase, muscle | -0.0223547 |
| PRKCA | protein kinase C, alpha | -0.0222174 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0220558 |
| AHNAK | AHNAK nucleoprotein | -0.0219672 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0219282 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.021489 |
| TJP1 | tight junction protein 1 | -0.0213961 |
| RPS29 | ribosomal protein S29 | -0.0213815 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.021123 |
| RPS21 | ribosomal protein S21 | -0.0210884 |
| INTS6 | integrator complex subunit 6 | -0.0209589 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0209469 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0209409 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0208795 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.020845 |
| CANX | calnexin | -0.0208365 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.020835 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0206887 |
| EHBP1 | EH domain binding protein 1 | -0.0203985 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0203489 |
| PCDH7 | protocadherin 7 | -0.0200549 |
| RIGI | RNA sensor RIG-I | -0.0200431 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0200316 |
| TMC5 | transmembrane channel-like 5 | -0.0199643 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0198499 |
| SQSTM1 | sequestosome 1 | -0.0196803 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0195791 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0194817 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.019398 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0192174 |
| RPS19 | ribosomal protein S19 | -0.0191249 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0188762 |
| GNAS | GNAS complex locus | -0.0188142 |
| KRT19 | keratin 19, type I | -0.0187141 |
| RPL34 | ribosomal protein L34 | -0.0183896 |
| RPS25 | ribosomal protein S25 | -0.0183708 |
| ACTG1 | actin gamma 1 | -0.0183669 |
| KYNU | kynureninase | -0.0181922 |
| RRBP1 | ribosome binding protein 1 | -0.0181133 |
| RACK1 | receptor for activated C kinase 1 | -0.0179225 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0178563 |
| RUNX1 | runt-related transcription factor 1 | -0.0178183 |
